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Volumn 11, Issue 6, 2011, Pages 482-490

Diagnostic exercise challenge testing

Author keywords

Asthma diagnostic challenge; Athlete; Exercise; Exercise challenge; Exercise induced bronchoconstriction; Pulmonary function; Surrogate; Testing

Indexed keywords

ADENOSINE PHOSPHATE; CORTICOSTEROID; HISTAMINE; MANNITOL; METHACHOLINE; SODIUM CHLORIDE;

EID: 81155152240     PISSN: 15297322     EISSN: 15346315     Source Type: Journal    
DOI: 10.1007/s11882-011-0225-4     Document Type: Review
Times cited : (15)

References (77)
  • 1
    • 78650832411 scopus 로고    scopus 로고
    • Bronchial provocation testing; The future
    • 21150437 10.1097/ACI.0b013e3283423183 This is an excellent discussion of the rationale and performance of the present direct and indirect challenges and the future of this testing
    • SD Anderson JD Brannan 2011 Bronchial provocation testing; the future Current Opinion in Allergy and Clinical Immunology 11 46 52 21150437 10.1097/ACI.0b013e3283423183 This is an excellent discussion of the rationale and performance of the present direct and indirect challenges and the future of this testing
    • (2011) Current Opinion in Allergy and Clinical Immunology , vol.11 , pp. 46-52
    • Anderson, S.D.1    Brannan, J.D.2
  • 2
    • 78650568036 scopus 로고    scopus 로고
    • Pathogenesis, prevalence, diagnosis and management of exercise-induced bronchoconstriction: A practice parameter
    • 10.1016/j.anai.2010.09.021 This is a comprehensive, state-of-the-art discussion developed by an international workforce of experts of the practice parameters for EIB. The discussion encompasses evidence-based guidelines for the definition, pathogenesis, diagnosis, and management of EIB with and without asthma for the recreational and competitive or elite athlete
    • J Weiler SD Anderson CC Randolph, et al. 2010 Pathogenesis, prevalence, diagnosis and management of exercise-induced bronchoconstriction: a practice parameter Annals Allergy Asthma Immunol 105 S1 S48 10.1016/j.anai.2010.09.021 This is a comprehensive, state-of-the-art discussion developed by an international workforce of experts of the practice parameters for EIB. The discussion encompasses evidence-based guidelines for the definition, pathogenesis, diagnosis, and management of EIB with and without asthma for the recreational and competitive or elite athlete
    • (2010) Annals Allergy Asthma Immunol , vol.105
    • Weiler, J.1    Anderson, S.D.2    Randolph, C.C.3
  • 3
    • 56649088178 scopus 로고    scopus 로고
    • Overdiagnosis of asthma in obese and nonobese adults
    • 19015563 10.1503/cmaj.081332
    • SD Aaron KL Vandemheem LP Boulet, et al. 2008 Overdiagnosis of asthma in obese and nonobese adults CMAJ 179 1121 1131 19015563 10.1503/cmaj.081332
    • (2008) CMAJ , vol.179 , pp. 1121-1131
    • Aaron, S.D.1    Vandemheem, K.L.2    Boulet, L.P.3
  • 4
    • 34250831546 scopus 로고    scopus 로고
    • Diagnostic tests for asthma in firefighters
    • DOI 10.1378/chest.06-2218
    • D Miedinger PN Chhajped M Tamm, et al. 2007 Diagnostic tests for asthma in firefighters Chest 131 1760 67 17400683 10.1378/chest.06-2218 (Pubitemid 46981631)
    • (2007) Chest , vol.131 , Issue.6 , pp. 1760-1767
    • David, M.1    Chhajed, P.N.2    Tamm, M.3    Stolz, D.4    Surber, C.5    Leuppi, J.D.6
  • 5
    • 74049156320 scopus 로고    scopus 로고
    • Asthma tests in the assessment of military conscripts
    • 19895592 10.1111/j.1365-2222.2009.03387.x 1:STN:280: DC%2BC3c7msVahug%3D%3D This was the first investigation using mannitol in a military setting. Mannitol and methacholine had similar sensitivity and specificity to physician diagnosis. Mannitol was less expensive because it did not require a nebulizer. Bronchoprovocation tests are useful as objective measures to confirm asthma in those candidates without objective testing
    • D Miedinger Mosimann R Meier, et al. 2010 Asthma tests in the assessment of military conscripts Clin Exp Allergy 40 224 31 19895592 10.1111/j.1365-2222. 2009.03387.x 1:STN:280:DC%2BC3c7msVahug%3D%3D This was the first investigation using mannitol in a military setting. Mannitol and methacholine had similar sensitivity and specificity to physician diagnosis. Mannitol was less expensive because it did not require a nebulizer. Bronchoprovocation tests are useful as objective measures to confirm asthma in those candidates without objective testing
    • (2010) Clin Exp Allergy , vol.40 , pp. 224-31
    • Miedinger, D.1    Mosimann2    Meier, R.3
  • 6
    • 78650554931 scopus 로고    scopus 로고
    • Diagnosis of exercise-induced bronchoconstriction: Eucapnic voluntary hyperpnea challenges identify previously undiagnosed elite athletes with exercise-induced bronchoconstriction
    • Epub ahead of print
    • Dickinson J, McConnell A, Whyte G. Diagnosis of exercise-induced bronchoconstriction: eucapnic voluntary hyperpnea challenges identify previously undiagnosed elite athletes with exercise-induced bronchoconstriction. Br J Sport Med 2010, Epub ahead of print.
    • (2010) Br J Sport Med
    • Dickinson, J.1    McConnell, A.2    Whyte, G.3
  • 10
    • 74049159957 scopus 로고    scopus 로고
    • Direct and indirect challenges in the clinical assessment of asthma
    • 10.1016/S1081-1206(10)60353-5 This is a comprehensive elucidation of the rationale for and performance of direct and indirect challenges
    • D Cockroft B Davis 2009 Direct and indirect challenges in the clinical assessment of asthma Ann Allergy Asthma Immunol 103 363 370 10.1016/S1081- 1206(10)60353-5 This is a comprehensive elucidation of the rationale for and performance of direct and indirect challenges
    • (2009) Ann Allergy Asthma Immunol , vol.103 , pp. 363-370
    • Cockroft, D.1    Davis, B.2
  • 11
    • 77956842995 scopus 로고    scopus 로고
    • Direct challenge tests
    • 20 less than 1 mg/mL, particularly if symptoms are reproducible from the history
    • 20 less than 1 mg/mL, particularly if symptoms are reproducible from the history
    • (2010) Chest , vol.138
    • Cockroft, D.W.1
  • 12
    • 77956832793 scopus 로고    scopus 로고
    • Indirect challenge tests: Airway hyperresponsiveness in asthma: Its measurement and clinical significance
    • 20668015 10.1378/chest.10-0116 1:CAS:528:DC%2BC3cXhtFaht77L This is a comprehensive discussion of the rationale and performance of indirect challenges for asthma diagnosis
    • SD Anderson 2010 Indirect challenge tests: Airway hyperresponsiveness in asthma: its measurement and clinical significance Chest 138 2 Suppl 25S 30S 20668015 10.1378/chest.10-0116 1:CAS:528:DC%2BC3cXhtFaht77L This is a comprehensive discussion of the rationale and performance of indirect challenges for asthma diagnosis
    • (2010) Chest , vol.138 , Issue.2 SUPPL.
    • Anderson, S.D.1
  • 13
    • 0018669745 scopus 로고
    • Bronchial responsiveness to inhaled histamine and exercise
    • DOI 10.1016/0091-6749(79)90125-8
    • SD Anderson J Brannan J Spring, et al. 1979 Bronchial responsiveness to inhaled histamine and exercise J Allergy Clin Immunol 63 5 315 320 10.1016/0091-6749(79)90125-8 (Pubitemid 10218812)
    • (1979) Journal of Allergy and Clinical Immunology , vol.63 , Issue.5 , pp. 315-320
    • Anderton, R.C.1    Cuff, M.T.2    Frith, P.A.3
  • 14
    • 0018759746 scopus 로고
    • A comparison of the asthmatic response to methacholine and exercise
    • PA Eggleston 1979 A comparison of the asthmatic response to methacholine and exercise J Allergy Clin Immunol 63 2 104 110 759463 10.1016/0091-6749(79) 90199-4 1:STN:280:DyaE1M%2FovFaktw%3D%3D (Pubitemid 9117174)
    • (1979) Journal of Allergy and Clinical Immunology , vol.63 , Issue.2 , pp. 104-110
    • Eggleston, P.A.1
  • 15
    • 0025174585 scopus 로고
    • Inhalational challenge using hypertonic saline in asthmatic subjects: A comparison with responses to hyperpnoea, methacholine and water
    • CM Smith SD Anderson 1990 Inhalational challenge using hypertonic saline in asthmatic subjects: a comparison with responses to hyperpnea, methacholine and water Eur Respir J 3920 144 151 (Pubitemid 20066914)
    • (1990) European Respiratory Journal , vol.3 , Issue.2 , pp. 144-151
    • Smith, C.M.1    Anderson, S.D.2
  • 16
    • 0345732433 scopus 로고    scopus 로고
    • Responsiveness to Three Bronchial Provocation Tests in Patients with Asthma
    • DOI 10.1378/chest.124.6.2171
    • HO Koskela L Hyvarinen JD Brannan, et al. 2003 Responsiveness to three bronchial provocation tests in patients with asthma Chest 124 6 2171 2177 14665497 10.1378/chest.124.6.2171 (Pubitemid 38010586)
    • (2003) Chest , vol.124 , Issue.6 , pp. 2171-2177
    • Koskela, H.O.1    Hyvarinen, L.2    Brannan, J.D.3    Chan, H.-K.4    Anderson, S.D.5
  • 17
    • 81155149118 scopus 로고    scopus 로고
    • Airway hyperresponsiveness to mannitol and methacholine in a random population sample of adolescents
    • Cockcroft 2010 35-40
    • Sverrild A, Porsbjerg C, Thomson SF, et al. Airway hyperresponsiveness to mannitol and methacholine in a random population sample of adolescents. J Allergy Clin Immunol 2009, 279: A2415 Cockcroft 2010: 35-40.
    • (2009) J Allergy Clin Immunol , vol.279
    • Sverrild, A.1    Porsbjerg, C.2    Thomson, S.F.3
  • 18
    • 36849010983 scopus 로고    scopus 로고
    • Relationship between airway responsiveness to mannitol and to methacholine and markers of airway inflammation, peak flow variability and quality of life in asthma patients
    • DOI 10.1111/j.1365-2222.2007.02878.x
    • C Porsbjerg JD Brannan SD Anderson, et al. 2008 Relationship between airway responsiveness to mannitol and to methacholine and markers of airway inflammation, peak flow variability and quality of life in asthma patients Clin Exp Allergy 38 1 43 50 18028458 1:STN:280:DC%2BD2sjkt12ksQ%3D%3D (Pubitemid 350233397)
    • (2008) Clinical and Experimental Allergy , vol.38 , Issue.1 , pp. 43-50
    • Porsbjerg, C.1    Brannan, J.D.2    Anderson, S.D.3    Backer, V.4
  • 19
    • 0036916503 scopus 로고    scopus 로고
    • Changes in sputum counts and airway hyperresponsiveness after budesonide: Monitoring anti-inflammatory response on the basis of surrogate markers of airway inflammation
    • DOI 10.1067/mai.2002.130050
    • G Prosperini K Rajakulasingam RR Cacciola, et al. 2002 Changes in sputum counts and airway hyperresponsiveness after budesonide monitoring anti-inflammatory response on the basis of surrogate markers of inflammation J Allergy Clin Immunol 110 6 855 61 12464950 10.1067/mai.2002.130050 1:CAS:528:DC%2BD3sXlvFegtA%3D%3D (Pubitemid 36005871)
    • (2002) Journal of Allergy and Clinical Immunology , vol.110 , Issue.6 , pp. 855-861
    • Prosperini, G.1    Rajakulasingam, K.2    Cacciola, R.R.3    Spicuzza, L.4    Rorke, S.5    Holgate, S.T.6    Di Maria, G.U.7    Polosa, R.8
  • 21
    • 79954571050 scopus 로고    scopus 로고
    • The occurrence of refractoriness and mast cell mediator release following mannitol-induced bronchoconstriction
    • 21252215 10.1152/japplphysiol.00978.2010
    • JR Larsson CP Perry SD Anderson, et al. 2011 The occurrence of refractoriness and mast cell mediator release following mannitol-induced bronchoconstriction J Appl Physiol 110 4 1029 35 21252215 10.1152/japplphysiol. 00978.2010
    • (2011) J Appl Physiol , vol.110 , Issue.4 , pp. 1029-35
    • Larsson, J.R.1    Perry, C.P.2    Anderson, S.D.3
  • 22
    • 77956570676 scopus 로고    scopus 로고
    • Airway hyperresponsiveness to methacholine, adenosine 5 monophosphate, mannitol, eucapnic voluntary hyperpoea and field exercise challenge in elite cross country skiers
    • 20460257 10.1136/bjsm.2009.071043 This study elucidated the lack of correlation between methacholine hyperresponsiveness, which is more common in asymptomatic skiers, and hyperresponsiveness to mannitol and hyperpnea. These results imply differences in the pathogenesis of methacholine hyperresponsiveness in elite skiers and individuals who are not athletes.
    • M Sue-Chu JD Brannan DS Anderson, et al. 2010 Airway hyperresponsiveness to methacholine, adenosine 5 monophosphate, mannitol, eucapnic voluntary hyperpoea and field exercise challenge in elite cross country skiers Br J Sports Med 44 827 832 20460257 10.1136/bjsm.2009.071043 This study elucidated the lack of correlation between methacholine hyperresponsiveness, which is more common in asymptomatic skiers, and hyperresponsiveness to mannitol and hyperpnea. These results imply differences in the pathogenesis of methacholine hyperresponsiveness in elite skiers and individuals who are not athletes.
    • (2010) Br J Sports Med , vol.44 , pp. 827-832
    • Sue-Chu, M.1    Brannan, J.D.2    Anderson, D.S.3
  • 23
    • 34848836705 scopus 로고    scopus 로고
    • Bronchial hyperresponsiveness in skiers: Field test versus methacholine provocation?
    • DOI 10.1249/mss.0b013e31813738ac, PII 0000576820071000000001
    • T Stensrud KV Mykland K Gabrielson, et al. 2007 Bronchial hyperresponsiveness in skiers: field test versus methacholine provocation Med Sci Sports Exerc 39 1681 1686 17909392 10.1249/mss.0b013e31813738ac (Pubitemid 47511472)
    • (2007) Medicine and Science in Sports and Exercise , vol.39 , Issue.10 , pp. 1681-1686
    • Stensrud, T.1    Mykland, K.V.2    Gabrielsen, K.3    Carlsen, K.-H.4
  • 24
    • 48349140740 scopus 로고    scopus 로고
    • Airway injury as a mechanism for exercise-induced bronchoconstriction in elite athletes
    • 18554705 10.1016/j.jaci.2008.05.001
    • SD Anderson P Kippelen 2008 Airway injury as a mechanism for exercise-induced bronchoconstriction in elite athletes J Allergy Clin Immunol 122 225 235 18554705 10.1016/j.jaci.2008.05.001
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 225-235
    • Anderson, S.D.1    Kippelen, P.2
  • 25
    • 70349244870 scopus 로고    scopus 로고
    • Current and future use of the mannitol bronchial challenge in every day clinical practice
    • 10.1111/j.1752-699X.2009.00161.x 1:CAS:528:DC%2BD1MXhtlehsrfI
    • C Porsbjerg V Backer G Joos, et al. 2009 Current and future use of the mannitol bronchial challenge in every day clinical practice Clin Resp J 3 189 197 10.1111/j.1752-699X.2009.00161.x 1:CAS:528:DC%2BD1MXhtlehsrfI
    • (2009) Clin Resp J , vol.3 , pp. 189-197
    • Porsbjerg, C.1    Backer, V.2    Joos, G.3
  • 26
    • 38749144863 scopus 로고    scopus 로고
    • Monitoring asthma therapy using indirect bronchoprovocation tests
    • 10.1111/j.1752-699X.2007.00004.x
    • JD Brannan H Koskela SD Anderson 2007 Monitoring asthma therapy using indirect bronchoprovocation tests Clin Resp J 1 3 15 10.1111/j.1752-699X.2007. 00004.x
    • (2007) Clin Resp J , vol.1 , pp. 3-15
    • Brannan, J.D.1    Koskela, H.2    Anderson, S.D.3
  • 27
    • 77956853364 scopus 로고    scopus 로고
    • Bronchial challenges and respiratory symptoms in elite swimmers and winter sports athletes
    • 10.1378/chest.09-1689
    • V Bougault LP Boulet J Turmel 2010 Bronchial challenges and respiratory symptoms in elite swimmers and winter sports athletes Chest 18 31S 37S 10.1378/chest.09-1689
    • (2010) Chest , vol.18
    • Bougault, V.1    Boulet, L.P.2    Turmel, J.3
  • 28
    • 79952104573 scopus 로고    scopus 로고
    • Respiratory symptoms and bronchial responsiveness in competitive swimmers
    • K Stadelmann T Stensrud KH Carlsen 2010 Respiratory symptoms and bronchial responsiveness in competitive swimmers Med Sci Sports Exerc 43 3 375 81
    • (2010) Med Sci Sports Exerc , vol.43 , Issue.3 , pp. 375-81
    • Stadelmann, K.1    Stensrud, T.2    Carlsen, K.H.3
  • 29
    • 34249738747 scopus 로고    scopus 로고
    • Airway reactivity to inhaled mannitol in cigarette smokers: A longitudinal study
    • DOI 10.1016/j.rmed.2007.01.008, PII S0954611107000145
    • D Stolz SD Anderson C Gysin, et al. 2007 Airway reactivity to inhaled mannitol in cigarette smokers: a longitudinal study Respir Med 101 1470 1476 17324566 10.1016/j.rmed.2007.01.008 (Pubitemid 46832228)
    • (2007) Respiratory Medicine , vol.101 , Issue.7 , pp. 1470-1476
    • Stolz, D.1    Anderson, S.D.2    Gysin, C.3    Miedinger, D.4    Surber, C.5    Tamm, M.6    D. Leuppi, J.7
  • 30
    • 61549111538 scopus 로고    scopus 로고
    • Comparison of mannitol and methacholine to predict exercise-induced bronchoconstriction and a clinical diagnosis of asthma
    • 19161635 This is a rigorous, state-of-the-art comparison of direct and indirect challenges for diagnosis of EIB in individuals without a defined diagnosis of asthma. The challenges were conducted after two traditional treadmill exercise challenges for reproducibility. The physician investigators made the diagnosis based on exercise challenge, pulmonary function data, and questionnaire blinded to the mannitol and methacholine challenge results. The sensitivity and specificity of methacholine and mannitol testing were similar at 55% to 65%
    • SD Anderson B Charlton JM Weiler, et al. 2009 Comparison of mannitol and methacholine to predict exercise-induced bronchoconstriction and a clinical diagnosis of asthma Respir Res 10 4 19161635 This is a rigorous, state-of-the-art comparison of direct and indirect challenges for diagnosis of EIB in individuals without a defined diagnosis of asthma. The challenges were conducted after two traditional treadmill exercise challenges for reproducibility. The physician investigators made the diagnosis based on exercise challenge, pulmonary function data, and questionnaire blinded to the mannitol and methacholine challenge results. The sensitivity and specificity of methacholine and mannitol testing were similar at 55% to 65%
    • (2009) Respir Res , vol.10 , pp. 4
    • Anderson, S.D.1    Charlton, B.2    Weiler, J.M.3
  • 31
    • 67650129284 scopus 로고    scopus 로고
    • Mannitol and exercise challenge tests in asthmatic children
    • 19499571 10.1002/ppul.21034 This was a pediatric study with mannitol versus exercise in the cold air concluding that mannitol is reliable as a diagnostic test to exclude EIB. The mannitol test had a median time of 24 minutes, compared with 40 minutes for exercise. The positive mannitol test had a median time of only 16 minutes
    • ET Kersten JM Driessen JD van der Berg, et al. 2009 Mannitol and exercise challenge tests in asthmatic children Pediatr Pulmonol 44 655 661 19499571 10.1002/ppul.21034 This was a pediatric study with mannitol versus exercise in the cold air concluding that mannitol is reliable as a diagnostic test to exclude EIB. The mannitol test had a median time of 24 minutes, compared with 40 minutes for exercise. The positive mannitol test had a median time of only 16 minutes
    • (2009) Pediatr Pulmonol , vol.44 , pp. 655-661
    • Kersten, E.T.1    Driessen, J.M.2    Van Der Berg, J.D.3
  • 32
    • 57249111844 scopus 로고    scopus 로고
    • The utility of the mannitol challenge in the assessment of chronic cough: A pilot study
    • 19017380 10.1186/1745-9974-4-10
    • A Singapuri S McKenna CE Brightling 2008 The utility of the mannitol challenge in the assessment of chronic cough: a pilot study Cough 4 10 19017380 10.1186/1745-9974-4-10
    • (2008) Cough , vol.4 , pp. 10
    • Singapuri, A.1    McKenna, S.2    Brightling, C.E.3
  • 33
    • 68849129027 scopus 로고    scopus 로고
    • Airway response to mannitol challenge in asthmatic children using impulse oscillometry
    • 19657902 10.1080/02770900903006265 1:CAS:528:DC%2BD1MXps1Krs7c%3D
    • TA Horsman RK Duke PW Davenport 2009 Airway response to mannitol challenge in asthmatic children using impulse oscillometry J Asthma 46 600 603 19657902 10.1080/02770900903006265 1:CAS:528:DC%2BD1MXps1Krs7c%3D
    • (2009) J Asthma , vol.46 , pp. 600-603
    • Horsman, T.A.1    Duke, R.K.2    Davenport, P.W.3
  • 34
    • 66749103923 scopus 로고    scopus 로고
    • The bronchial response to mannitol is attenuated by previous methacholine not vice versa
    • Gade E, Thomsen SF, Porsbjerg C, et al. The bronchial response to mannitol is attenuated by previous methacholine not vice versa. Clin Exp Allergy 2009, 966-971.
    • (2009) Clin Exp Allergy , pp. 966-971
    • Gade, E.1    Thomsen, S.F.2    Porsbjerg, C.3
  • 35
    • 77953329105 scopus 로고    scopus 로고
    • Sodium cromoglycate alone and in combination with montelukast on the airway response to mannitol in asthmatic subjects
    • 20528598 10.3109/02770900903584043 1:CAS:528:DC%2BC3cXnt12htLs%3D
    • SD Anderson JD Brannan CP Perry, et al. 2010 Sodium cromoglycate alone and in combination with montelukast on the airway response to mannitol in asthmatic subjects J Asthma 47 429 433 20528598 10.3109/02770900903584043 1:CAS:528:DC%2BC3cXnt12htLs%3D
    • (2010) J Asthma , vol.47 , pp. 429-433
    • Anderson, S.D.1    Brannan, J.D.2    Perry, C.P.3
  • 36
    • 77957350004 scopus 로고    scopus 로고
    • Effect of sodium cromoglycate on mast cell mediators during hyperpnea in athletes
    • 20216468 10.1249/MSS.0b013e3181da4f7d 1:CAS:528:DC%2BC3cXhtFOktLzF
    • P Kippelen J Larsson SD Anderson, et al. 2010 Effect of sodium cromoglycate on mast cell mediators during hyperpnea in athletes Med Sci Sports Exerc 42 10 1853 60 20216468 10.1249/MSS.0b013e3181da4f7d 1:CAS:528: DC%2BC3cXhtFOktLzF
    • (2010) Med Sci Sports Exerc , vol.42 , Issue.10 , pp. 1853-60
    • Kippelen, P.1    Larsson, J.2    Anderson, S.D.3
  • 37
    • 75149135700 scopus 로고    scopus 로고
    • Acute effects of beclometasone on hypnoea-induced bronchoconstriction
    • 19927031 10.1249/MSS.0b013e3181b541b1 1:CAS:528:DC%2BC3cXpsVSnsw%3D%3D
    • P Kippelen J Larsson SD Anderson, et al. 2010 Acute effects of beclometasone on hypnoea-induced bronchoconstriction Med Sci Sports Exerc 42 2 273 80 19927031 10.1249/MSS.0b013e3181b541b1 1:CAS:528:DC%2BC3cXpsVSnsw%3D%3D
    • (2010) Med Sci Sports Exerc , vol.42 , Issue.2 , pp. 273-80
    • Kippelen, P.1    Larsson, J.2    Anderson, S.D.3
  • 39
    • 48449087408 scopus 로고    scopus 로고
    • Asthma and the elite athlete: Summary of the International Olympic Committee's Consensus Conference, Lausanne, Switzerland, Jan 22-24
    • 18678340 10.1016/j.jaci.2008.07.003
    • KD Fitch M Sue-Chu SD Anderson, et al. 2008 Asthma and the elite athlete: summary of the International Olympic Committee's Consensus Conference, Lausanne, Switzerland, Jan 22-24 J Allergy Clin Immunol 122 254 260 18678340 10.1016/j.jaci.2008.07.003
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 254-260
    • Fitch, K.D.1    Sue-Chu, M.2    Anderson, S.D.3
  • 40
    • 0015456129 scopus 로고
    • Standardization of exercise tests in asthmatic children
    • 4647044 10.1136/adc.47.256.882 1:STN:280:DyaE3s%2FotVSlsg%3D%3D
    • M Silverman SD Anderson 1972 Standardization of exercise tests in asthmatic children Arch Dis Child 47 882 9 4647044 10.1136/adc.47.256.882 1:STN:280:DyaE3s%2FotVSlsg%3D%3D
    • (1972) Arch Dis Child , vol.47 , pp. 882-9
    • Silverman, M.1    Anderson, S.D.2
  • 41
    • 1642289193 scopus 로고    scopus 로고
    • Field exercise vs laboratory eucapnic voluntary hyperventilation to identify airway hyperresponsiveness in elite cold weather athletes
    • DOI 10.1378/chest.125.3.909
    • KW Rundell SD Anderson BA Spiering, et al. 2004 Field exercise vs. laboratory eucapnic voluntary hyperventilation to identify airway hyperresponsiveness in elite cold weather athletes Chest 125 909 915 15006949 10.1378/chest.125.3.909 (Pubitemid 38367281)
    • (2004) Chest , vol.125 , Issue.3 , pp. 909-915
    • Rundell, K.W.1    Anderson, S.D.2    Spiering, B.A.3    Judelson, D.A.4
  • 42
    • 70249120670 scopus 로고    scopus 로고
    • The clinical utility of eucapnic voluntary hyperventilation for the diagnosis of exercise induced bronchospasm
    • 10.1080/02770900902972178 This was the first study of eucapnic hyperventilation used in a tertiary care center pulmonary laboratory in the United States. The usefulness of the test was evaluated for diagnosis of EIB with threshold ventilation of 60% of maximum voluntary ventilation required for an acceptable test, with 80% of males, but only 55% of females successfully reaching the threshold. A total of 81% of the tests were diagnostic, with 28% diagnosed with EIB. A total of 33% of the inadequate tests were EIB positive, and 16 of 17 were female. The authors concluded that EVH is a reliable modality to diagnose EIB in a pulmonary practice setting
    • NE Bummel JG Mastronarde D Rittinger, et al. 2009 The clinical utility of eucapnic voluntary hyperventilation for the diagnosis of exercise induced bronchospasm J Asthma 46 683 686 10.1080/02770900902972178 This was the first study of eucapnic hyperventilation used in a tertiary care center pulmonary laboratory in the United States. The usefulness of the test was evaluated for diagnosis of EIB with threshold ventilation of 60% of maximum voluntary ventilation required for an acceptable test, with 80% of males, but only 55% of females successfully reaching the threshold. A total of 81% of the tests were diagnostic, with 28% diagnosed with EIB. A total of 33% of the inadequate tests were EIB positive, and 16 of 17 were female. The authors concluded that EVH is a reliable modality to diagnose EIB in a pulmonary practice setting
    • (2009) J Asthma , vol.46 , pp. 683-686
    • Bummel, N.E.1    Mastronarde, J.G.2    Rittinger, D.3
  • 43
    • 68849086058 scopus 로고    scopus 로고
    • Inflammatory subtypes on asthma are related to airway hyperresponsiveness to mannitol and exhaled nitric oxide
    • 19657904 10.1080/02770900903015654 1:CAS:528:DC%2BD1MXps1Krs7Y%3D
    • C Porsbjerg TK Lund L Pedersn, et al. 2009 Inflammatory subtypes on asthma are related to airway hyperresponsiveness to mannitol and exhaled nitric oxide J Asthma 46 606 612 19657904 10.1080/02770900903015654 1:CAS:528:DC%2BD1MXps1Krs7Y%3D
    • (2009) J Asthma , vol.46 , pp. 606-612
    • Porsbjerg, C.1    Lund, T.K.2    Pedersn, L.3
  • 44
    • 74049089321 scopus 로고    scopus 로고
    • Mannitol challenge for assessment of airway responsiveness, airway inflammation and inflammatory phenotype in asthma
    • 19878195 10.1111/j.1365-2222.2009.03371.x 1:CAS:528:DC%2BC3cXitFKgsLY%3D
    • LG Wood H Powell PG Gibson 2010 Mannitol challenge for assessment of airway responsiveness, airway inflammation and inflammatory phenotype in asthma Clin Exp Allergy 40 232 41 19878195 10.1111/j.1365-2222.2009.03371.x 1:CAS:528:DC%2BC3cXitFKgsLY%3D
    • (2010) Clin Exp Allergy , vol.40 , pp. 232-41
    • Wood, L.G.1    Powell, H.2    Gibson, P.G.3
  • 45
    • 10744233004 scopus 로고    scopus 로고
    • Sensitivity and Validity of Three Bronchial Provocation Tests to Demonstrate the Effect of Inhaled Corticosteroids in Asthma
    • DOI 10.1378/chest.124.4.1341
    • H Koskela L Hyvarinen JD Brannan, et al. 2003 Sensitivity and validity of three bronchial provocation tests to demonstrate the effect of inhaled corticosteroids in asthma Chest 124 1341 9 14555564 10.1378/chest.124.4.1341 1:CAS:528:DC%2BD3sXovF2hs78%3D (Pubitemid 37290044)
    • (2003) Chest , vol.124 , Issue.4 , pp. 1341-1349
    • Koskela, H.O.1    Hyvarinen, L.2    Brannan, J.D.3    Chan, H.-K.4    Anderson, S.D.5
  • 46
    • 77951735251 scopus 로고    scopus 로고
    • Exercise-induced wheeze: Fraction of exhaled nitric oxide directed management
    • 20337988 10.1111/j.1440-1843.2010.01740.x
    • SC Cowan RS Hewitt JO Cowan, et al. 2010 Exercise-induced wheeze: fraction of exhaled nitric oxide directed management Respirology 15 683 690 20337988 10.1111/j.1440-1843.2010.01740.x
    • (2010) Respirology , vol.15 , pp. 683-690
    • Cowan, S.C.1    Hewitt, R.S.2    Cowan, J.O.3
  • 47
    • 33646901630 scopus 로고    scopus 로고
    • The role of the mast cell in the pathophysiology of asthma
    • DOI 10.1016/j.jaci.2006.02.039, PII S0091674906005148
    • P Bradding AF Walls ST Holgate 2006 The role of the mast cell in the pathophysiology of asthma J Allergy Clin Immunol 117 1277 1284 16750987 10.1016/j.jaci.2006.02.039 1:CAS:528:DC%2BD28XlsVaqt7c%3D (Pubitemid 43795741)
    • (2006) Journal of Allergy and Clinical Immunology , vol.117 , Issue.6 , pp. 1277-1284
    • Bradding, P.1    Walls, A.F.2    Holgate, S.T.3
  • 48
    • 0034047733 scopus 로고    scopus 로고
    • Evidence of airway inflammation and remodeling in ski athletes with and without bronchial hyperresponsiveness to methacholine
    • EM Karjalainen A Laitinen M Sue-Chu, et al. 2000 Evidence of airway inflammation and remodeling in ski athletes with and without bronchial hyperresponsiveness to methacholine Am J Respir Crit Care 161 2089 91
    • (2000) Am J Respir Crit Care , vol.161 , pp. 2089-91
    • Karjalainen, E.M.1    Laitinen, A.2    Sue-Chu, M.3
  • 49
    • 0036023682 scopus 로고    scopus 로고
    • A study of the association between exercise-induced wheeze and exercise versus methacholine-induced bronchoconstriction in adolescents
    • 12144643 10.1034/j.1399-3038.2002.01034.x
    • AN Henriksen KH Tveit TL Holmen, et al. 2002 A study of the association between exercise-induced wheeze and exercise versus methacholine-induced bronchoconstriction in adolescents Pediatr Allergy Immunol 13 203 8 12144643 10.1034/j.1399-3038.2002.01034.x
    • (2002) Pediatr Allergy Immunol , vol.13 , pp. 203-8
    • Henriksen, A.N.1    Tveit, K.H.2    Holmen, T.L.3
  • 50
    • 48349104221 scopus 로고    scopus 로고
    • Exercise and other indirect challenges to demonstrate asthma or exercise-induced bronchoconstriction in athletes
    • 18678339 10.1016/j.jaci.2008.06.014 This is a comprehensive review of direct and indirect challenges, the rationale and performance, as well as the necessity to diagnose asthma- or exercise-induced bronchoconstriction
    • KW Rundell JB Slee 2008 Exercise and other indirect challenges to demonstrate asthma or exercise-induced bronchoconstriction in athletes J Allergy Clin Immunol 122 238 48 18678339 10.1016/j.jaci.2008.06.014 This is a comprehensive review of direct and indirect challenges, the rationale and performance, as well as the necessity to diagnose asthma- or exercise-induced bronchoconstriction
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 238-48
    • Rundell, K.W.1    Slee, J.B.2
  • 52
    • 0033859934 scopus 로고    scopus 로고
    • Exercise-induced bronchoconstriction depends on exercise load
    • DOI 10.1053/rmed.2000.0809
    • KH Carlsen G Enigh M Mork 2000 Exercise-induced bronchoconstriction depends on exercise load Respir Med 94 750 5 10955749 10.1053/rmed.2000.0809 1:STN:280:DC%2BD3cvjtFemtA%3D%3D (Pubitemid 30628235)
    • (2000) Respiratory Medicine , vol.94 , Issue.8 , pp. 750-755
    • Carlsen, K.-H.1    Engh, G.2    MOrk, M.3
  • 53
    • 0019941156 scopus 로고
    • Sensitivity to heat and water loss at rest and during exercise in asthmatic patients
    • SD Anderson RE Schoeffel R Follet, et al. 1982 Sensitivity to heat and water loss at rest and during exercise in asthmatic patients Eur J Resp Dis 63 459 71 1:STN:280:DyaL3s%2FltlKrtw%3D%3D (Pubitemid 12029106)
    • (1982) European Journal of Respiratory Diseases , vol.63 , Issue.5 , pp. 459-471
    • Anderson, S.D.1    Schoeffel, R.E.2    Follet, R.3
  • 54
    • 33745578569 scopus 로고    scopus 로고
    • Vehicular air pollution, playgrounds, and youth athletic fields
    • DOI 10.1080/08958370600685640, PII H8237013750153
    • KW Rundell R Caviston AM Hollenbach, et al. 2006 Vehicular air pollution, playgrounds and youth athletic fields Inhal Toxicol 18 541 7 16717025 10.1080/08958370600685640 1:CAS:528:DC%2BD28XmvVamtLc%3D (Pubitemid 43977249)
    • (2006) Inhalation Toxicology , vol.18 , Issue.8 , pp. 541-547
    • Rundell, K.1    Caviston, R.2    Hollenbach, A.3    Murphy, K.4
  • 55
    • 16444365629 scopus 로고    scopus 로고
    • Cold air inhalation does not affect the severity of EIB after exercise or eucapnic voluntary hyperventilation
    • DOI 10.1249/01.MSS.0000158186.32450.EC
    • TM Evans KW Rundell KC Beck, et al. 2005 Cold air inhalation does not affect the severity of EIB after exercise or eucapneic hyperventilation Med Sci Sports Exerc 37 544 9 15809550 10.1249/01.MSS.0000158186.32450.EC (Pubitemid 40478457)
    • (2005) Medicine and Science in Sports and Exercise , vol.37 , Issue.4 , pp. 544-549
    • Evans, T.M.1    Rundell, K.W.2    Beck, K.C.3    Levine, A.M.4    Baumann, J.M.5
  • 56
    • 0016660108 scopus 로고
    • The use of treadmill for assessing exercise-induced asthma and the effect of varying the severity and the duration of exercise
    • SUPPL 1187281 1:STN:280:DyaE28%2Flt1WrtA%3D%3D
    • S Godfrey M Silverman SD Anderson, et al. 1975 The use of treadmill for assessing exercise-induced asthma and the effect of varying the severity and the duration of exercise Pediatrics 56 5, pt 2 suppl 893 8 1187281 1:STN:280:DyaE28%2Flt1WrtA%3D%3D
    • (1975) Pediatrics , vol.56 , Issue.5 PART 2 , pp. 893-8
    • Godfrey, S.1    Silverman, M.2    Anderson, S.D.3
  • 57
    • 0029076944 scopus 로고
    • An exercise challenge for epidemiological studies of childhood asthma: Validity and repeatability
    • 1:STN:280:DyaK2MzosFOmuw%3D%3D
    • MM Haby JK Peat CM Mellis, et al. 1995 An exercise challenge for epidemiological studies of childhood asthma: validity and repeatability Eur Resp J 8 729 36 1:STN:280:DyaK2MzosFOmuw%3D%3D
    • (1995) Eur Resp J , vol.8 , pp. 729-36
    • Haby, M.M.1    Peat, J.K.2    Mellis, C.M.3
  • 58
    • 0032885305 scopus 로고    scopus 로고
    • Cut-off points defining normal and asthmatic bronchial reactivity to exercise and inhalation challenges in children and young adults
    • DOI 10.1034/j.1399-3003.1999.14c28.x
    • S Godfrey C Springer E Bar-Yishay, et al. 1999 Cut-off points defining normal and asthmatic bronchial reactivity to exercise and inhalation challenges in children and young adults Eur Respir J 14 659 68 10543290 10.1034/j.1399-3003.1999.14c28.x 1:STN:280:DC%2BD3c%2FgvVKhtQ%3D%3D (Pubitemid 29479734)
    • (1999) European Respiratory Journal , vol.14 , Issue.3 , pp. 659-668
    • Godfrey, S.1    Springer, C.2    Bar-Yishay, E.3    Avital, A.4
  • 61
    • 0033966788 scopus 로고    scopus 로고
    • Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board Directors July 1999
    • 10619836 1:STN:280:DC%2BD3c%2FoslelsA%3D%3D
    • RO Crapo R Casaburi AL Coates, et al. 2000 Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board Directors July 1999 Am J Resp Crit Care Med 161 309 329 10619836 1:STN:280:DC%2BD3c%2FoslelsA%3D%3D
    • (2000) Am J Resp Crit Care Med , vol.161 , pp. 309-329
    • Crapo, R.O.1    Casaburi, R.2    Coates, A.L.3
  • 62
    • 0242624327 scopus 로고    scopus 로고
    • Clinical exercise testing with reference to lung disease: Indication, standardization and interpretation strategies
    • ERS Task Force on Standardization of Clinical Exercise Testing: European Respiratory Society
    • Clinical exercise testing with reference to lung disease: indication, standardization and interpretation strategies. ERS Task Force on Standardization of Clinical Exercise Testing: European Respiratory Society. Eur Resp J 1997, 10:2662-89.
    • (1997) Eur Resp J , vol.10 , pp. 2662-89
  • 63
    • 0035162504 scopus 로고    scopus 로고
    • Age-predicted maximal heart rate revisited
    • DOI 10.1016/S0735-1097(00)01054-8, PII S0735109700010548
    • H Tanaka KD Monahan DR Seals 2001 Age-predicted maximal heart rate revisited J Am Coll Cardiol 37 153 6 11153730 10.1016/S0735-1097(00)01054-8 1:STN:280:DC%2BD3M%2Fptlyrsg%3D%3D (Pubitemid 32051731)
    • (2001) Journal of the American College of Cardiology , vol.37 , Issue.1 , pp. 153-156
    • Tanaka, H.1    Monahan, K.D.2    Seals, D.R.3
  • 65
    • 9144230358 scopus 로고    scopus 로고
    • 1
    • DOI 10.1081/JAS-200028004
    • BA Spiering DA Judelson KW Rundell 2004 An evaluation of standardized target ventilation for eucapnic voluntary hyperventilation using FEVI J Asthma 41 745 9 15584634 10.1081/JAS-200028004 (Pubitemid 39546320)
    • (2004) Journal of Asthma , vol.41 , Issue.7 , pp. 745-749
    • Spiering, B.A.1    Judelson, D.A.2    Rundell, K.W.3
  • 67
    • 0028219979 scopus 로고
    • An exercise challenge protocol for epidemiological studies of asthma in children: Comparison with histamine challenge
    • MM Haby SD Anderson JK Peat, et al. 1994 An exercise challenge protocol for epidemiological studies of asthma in children: comparison with histamine challenge Eur Respir J 7 43 9 8143831 10.1183/09031936.94.07010043 1:STN:280:DyaK2c7pt1Orsw%3D%3D (Pubitemid 24075123)
    • (1994) European Respiratory Journal , vol.7 , Issue.1 , pp. 43-49
    • Haby, M.M.1    Anderson, S.D.2    Peat, J.K.3    Mellis, C.M.4    Toelle, B.G.5    Woolcock, A.J.6
  • 69
    • 0037227670 scopus 로고    scopus 로고
    • Bronchoconstriction during cross-country skiing: Is there really a refractory period?
    • DOI 10.1097/00005768-200301000-00004
    • KW Rundell BA Spierling DA Judelson, et al. 2003 Bronchconstriction during cross-country skiing: is there really a refractory period? Med Sci Sports 35 1 18 26 10.1097/00005768-200301000-00004 (Pubitemid 36084135)
    • (2003) Medicine and Science in Sports and Exercise , vol.35 , Issue.1 , pp. 18-26
    • Rundell, K.W.1    Spiering, B.A.2    Judelson, D.A.3    Wilson, M.H.4
  • 70
    • 2442642872 scopus 로고    scopus 로고
    • Screening of athletes for exercise-induced bronchoconstriction
    • DOI 10.1097/00042752-200405000-00005
    • K Holzer P Brukner 2004 Screening of athletes for exercise-induced bronchoconstriction Clin J Sports Medicine 14 3 134 8 10.1097/00042752- 200405000-00005 (Pubitemid 38669020)
    • (2004) Clinical Journal of Sport Medicine , vol.14 , Issue.3 , pp. 134-138
    • Holzer, K.1    Brukner, P.2
  • 71
    • 0028297802 scopus 로고
    • Eucapnic voluntary hyperventilation as a bronchoprovocation technique: Comparison with methacholine inhalation in asthmatics
    • JM Roach KM Hurwitz GJ Argyros, et al. 1994 Eucapnic voluntary hyperventilation as a bronchoprovocation technique. Comparison with methacholine inhalation in asthmatic Chest 105 667 72 8131523 10.1378/chest.105.3.667 1:STN:280:DyaK2c7nsl2rtg%3D%3D (Pubitemid 24088438)
    • (1994) Chest , vol.105 , Issue.3 , pp. 667-672
    • Roach, J.M.1    Hurwitz, K.M.2    Argyros, G.J.3    Eliasson, A.H.4    Phillips, Y.Y.5
  • 72
    • 0036738469 scopus 로고    scopus 로고
    • Exercise in elite summer athletes: Challenges for diagnosis
    • 12209082 10.1067/mai.2002.127784
    • K Holzer SD Anderson J Douglass 2002 Exercise in elite summer athletes: challenges for diagnosis J Allergy Clin Immunol 110 3 374 80 12209082 10.1067/mai.2002.127784
    • (2002) J Allergy Clin Immunol , vol.110 , Issue.3 , pp. 374-80
    • Holzer, K.1    Anderson, S.D.2    Douglass, J.3
  • 73
    • 0034805658 scopus 로고    scopus 로고
    • Provocation by eucapnic voluntary hyperpnoea to identify exercise induced bronchoconstriction
    • DOI 10.1136/bjsm.35.5.344
    • SD Anderson GJ Argyros H Magnussen, et al. 2001 Provocation by eucapnic voluntary hyperpnea to identify exercise-induced bronchoconstriction Br J Sports Medical 5 344 7 10.1136/bjsm.35.5.344 (Pubitemid 32929823)
    • (2001) British Journal of Sports Medicine , vol.35 , Issue.5 , pp. 344-347
    • Anderson, S.D.1    Argyros, G.J.2    Magnussen, H.3    Holzer, K.4
  • 74
    • 77955286981 scopus 로고    scopus 로고
    • The role of bronchial provocation challenge in the diagnosis of exercise-induced bronchoconstriction in elite swimmers
    • 18948353 10.1136/bjsm.2008.051169 1:STN:280:DC%2BC3cjhtVyhtw%3D%3D
    • A Castricum K Holzer P Brukner, et al. 2010 The role of bronchial provocation challenge in the diagnosis of exercise-induced bronchoconstriction in elite swimmers Br J Sports Med 44 736 40 18948353 10.1136/bjsm.2008.051169 1:STN:280:DC%2BC3cjhtVyhtw%3D%3D
    • (2010) Br J Sports Med , vol.44 , pp. 736-40
    • Castricum, A.1    Holzer, K.2    Brukner, P.3
  • 75
    • 0037441782 scopus 로고    scopus 로고
    • Mannitol as a challenge test to identify exercise induced bronchoconstriction in elite athletes
    • 10.1164/rccm.200208-916OC
    • K Holzer SD Anderson HK Chan, et al. 2003 Mannitol as a challenge test to identify exercise induced bronchoconstriction in elite athletes Am J Respir Crit Care Med 15 167 534 7 10.1164/rccm.200208-916OC
    • (2003) Am J Respir Crit Care Med , vol.15 , Issue.167 , pp. 534-7
    • Holzer, K.1    Anderson, S.D.2    Chan, H.K.3
  • 76
    • 81155146328 scopus 로고    scopus 로고
    • Simplified method for eucapnic voluntary hyperventilation (EVH) challenge abstract #26 online
    • Rosenthal R, Howe H: Simplified method for eucapnic voluntary hyperventilation (EVH) challenge abstract #26 online. J Allergy Clin Immunol 2011.
    • (2011) J Allergy Clin Immunol
    • Rosenthal, R.1    Howe, H.2
  • 77
    • 0036338813 scopus 로고    scopus 로고
    • Budesonide reduces sensitivity and reactivity to inhaled mannitol in asthmatic subjects
    • DOI 10.1046/j.1440-1843.2002.00357.x
    • JD Brannan H Koskela SD Anderson, et al. 2002 Budesonide reduces sensitivity and reactivity to inhaled mannitol in asthmatic subjects Respirology 7 37 44 11896899 10.1046/j.1440-1843.2002.00357.x (Pubitemid 34856893)
    • (2002) Respirology , vol.7 , Issue.1 , pp. 37-44
    • Brannan, J.D.1    Koskela, H.2    Anderson, S.D.3    Chan, H.K.4


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