Meta-analysis of the effectiveness and safety of prophylactic use of nimodipine in patients with an aneurysmal subarachnoid haemorrhage

CNS and Neurological Disorders - Drug Targets

Volumn 10, Issue 7, 2011, Pages 834-844

  Liu, Guang Jian ^a   Luo, Jie ^a   Zhang, Li Ping ^a   Wang, Zheng Jun ^a   Xu, Li Li ^a   He, Guo Hou ^a   Zeng, Yan Jun ^b   Wang, Yun Fu ^a  

^a HUBEI UNIVERSITY OF MEDICINE   (China)

^b BEIJING UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Aneurysmal subarachnoid haemorrhage; Cerebral vasospasm; Clinical outcome; Delayed neurological function deficits; Meta analysis; Nimodipine

Indexed keywords

NIMODIPINE; PLACEBO;

ARTICLE; BRAIN INFARCTION; BRAIN VASOSPASM; COMPUTER ASSISTED TOMOGRAPHY; CONVALESCENCE; DEATH; DISABILITY; DRUG EFFICACY; DRUG SAFETY; HUMAN; META ANALYSIS; PERSISTENT VEGETATIVE STATE; RECURRENT DISEASE; SUBARACHNOID HEMORRHAGE; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT;

EID: 81155125753     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/187152711798072383     Document Type: Article

References (58)

1. th July, 2011]. Available from: http://www.freefullpdf.com/results.html?cref=http%3A%2F%cof=FORID%3A11&q=Acute+systemic+erythropoietin+therapy+to+reduce+delayed+ischemic+deficits+following+aneurysmal+subarachnoid+hemorrhage%3A+a+Phase+II+randomized%2C+double-blind%2C+placebo-controlled+trial&sa=Search&as_qdr=all#815
2. Schmidt, U.; Bittner, E.; Pivi, S.; Marota, J.J. Hemodynamic management and outcome of patients treated for cerebral vasospasm with intraarterial nicardipine and/or milrinone. Anesth. Analg., 2010, 110, 895-902.
3. Nishiguchi, M.; Ono, S.; Iseda, K.; Manabe, H.; Hishikawa, T.; Date, I. Effect of vasodilation by milrinone, a phosphodiesterase III inhibitor, on vasospastic arteries after a subarachnoid hemorrhage in vitro and in vivo, effectiveness of cisternal injection of milrinone. Neurosurgery, 2010, 66, 158-164.
4. Pierot, L.; Aggour, M.; Moret, J. Vasospasm after aneurismal subarachnoid hemorrhage, recent advances in endovascular management. Curr. Opin. Crit. Care, 2010, epub ahead of print.
5. Kramer, A.; Fletcher, J. Do endothelin-receptor antagonists prevent delayed neurological deficits and poor outcomes after aneurysmal subarachnoid hemorrhage? A meta-analysis. Stroke, 2009, 40, 3403-3406.
6. Zhang, S.; Wang, L.; Liu, M.; Wu, B. Tirilazad for aneurismal subarachnoid haemorrhage. Cochrane Database Syst. Rev., 2010, 2, CD006778.
7. Jang, Y.G.; Ilodigwe, D.; Macdonald, R.L. Metaanalysis of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage. Neurocrit. Care, 2009, 10, 141-147.
8. Zwienenberg-Lee, M.; Hartman, J.; Rudisill, N.; Madden, L.K.; Smith, K.; Eskridge, J.; Newell, D.; Verweij, B.; Bullock, M.R.; Baker, A.; Coplin, W.; Mericle, R.; Dai, J.; Rocke, D.; Muizelaar, J.P. Effect of prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with Fisher grade III subarachnoid hemorrhage, results of a phase II multicenter, randomized, clinical trial. Stroke, 2008, 39, 1759-1765.
9. Treggiari, M.M.; Deem, S. Which H is the most important in triple-H therapy for cerebral vasospasm. Curr. Opin. Crit. Care, 2009, 15, 83-86.
10. Liu, X.B.; Wang, J.A.; Yu, S.P.; Keogh, C.L.; Wei, L. Therapeutic strategy of erythropoietin in neurological disorders. CNS Neurol. Disord. Drug Targets, 2008, 7, 227-234.
11. Tseng, M.Y.; Hutchinson, P.J.; Richards, H.K.; Czosnyka, M.; Pickard, J.D.; Erber, W.N.; Brown, S.; Kirkpatrick, P.J. Acute systemic erythropoietin therapy to reduce delayed ischemic deficits following aneurysmal subarachnoid hemorrhage, a Phase II randomized, double-blind, placebo-controlled trial. Clinical article. J. Neurosurg., 2009, 111, 171-180.
12. th July, 2011).
13. Turner, J.D.; Mammis, A.; Prestigiacomo, C.J. Erythropoietin for the treatment of subarachnoid hemorrhage, a review. World Neurosurg., 2010, 73, 500-507.
14. Yin, Y.H.; Wang, F.; Pan, Y.H.; Wang, Y.; Wang, Y.; Luo, Q.Z.; Jiang, J.Y. Effects of dose-response of topical administration of nimodipine on cerebral vasospasm after subarachnoid hemorrhage in rabbits. Am. J. Med. Sci., 2009, 337, 123-125.
15. Allen, G.S.; Ahn, H.S.; Preziosi, T.J.; Battye, R.; Boone, S.C.; Boone, S.C.; Chou, S.N.; Kelly, D.L.; Weir, B.K.; Crabbe, R.A.; Lavik, P.J.; Rosenbloom, S.B.; Dorsey, F.C.; Ingram, C.R.; Mellits, D.E.; Bertsch, L.A.; Boisvert, D.P.; Hundley, M.B.; Johnson, R.K.; Strom, J.A.; Transou, C.R. Cerebral arterial spasm--a controlled trial of nimodipine in patients with subarachnoid hemorrhage. N. Engl. J. Med., 1983, 308, 619-624.
16. Philippon, J.; Grob, R.; Dagreou, F.; Guggiari, M.; Rivierez, M.; Viars, P. Prevention of vasospasm in subarachnoid haemorrhage. A controlled study with nimodipine. Acta Neurochir., 1986, 82, 110-114.
17. Messeter, K.; Brandt, L.; Ljunggren, B.; Svendgaard, N.A.; Algotsson, L.; Romner, B.; Ryding, E. Prediction and prevention of delayed ischemic dysfunction after aneurysmal subarachnoid hemorrhage and early operation. Neurosurgery, 1987, 20, 548-553.
18. Jan, M.; Buchheit, F.; Tremoulet, M. Therapeutic trial of intravenous nimodipine in patients with established cerebral vasospasm after rupture of intracranial aneurysms. Neurosurgery, 1988, 23, 154-157.
19. Mee, E.; Dorrance, D.; Lowe, D.; Neil-Dwyer, G. Controlled study of nimodipine in aneurysm patients treated early after subarachnoid hemorrhage. Neurosurgery, 1988, 22, 484-491.
20. Petruk, K.C.; West, M.; Mohr, G.; Weir, B.K.; Benoit, B.G.; Gentili, F.; Disney, L.B.; Khan, M.I.; Grace, M.; Holness, R.O. Nimodipine treatment in poor-grade aneurysm patients. Results of a multicenter double-blind placebo-controlled trial. J. Neurosurg., 1988, 68, 505-517.
21. Pickard, J.D.; Murray, G.D.; Illingworth, R.; Shaw, M.D.; Teasdale, G.M.; Foy, P.M.; Humphrey, P.R.; Lang, D.A.; Nelson, R.; Richards, P. Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage, British aneurysm nimodipine trial. BMJ, 1989, 298, 636-642.
22. Ohman, J.; Servo, A.; Heiskanen, O. Risks factors for cerebral infarction in good-grade patients after aneurysmal subarachnoid hemorrhage and surgery, a prospective study. J. Neurosurg., 1991, 74, 14-20.
23. Han, D.H.; Lee, S.H.; Lee, S.H. Effect of nimodipine treatment on outcome in surgical cases of aneurysmal SAH. J. Neurosurg., 1993, 78, 346A.
24. Toni, D.; Frontoni, M.; Argentino, C.; Sacchetti, M.L.; De Michele, M.; Fieschi, C. Update on calcium antagonists in cerebrovascular diseases. J. Cardiovasc. Pharmacol., 1991, 18(Suppl 8), S10-S14.
25. Barker, F.G.; Ogilvy, C.S. Efficacy of prophylactic nimodipine for delayed ischemic deficit after subarachnoid hemorrhage, a metaanalysis. J. Neurosurg., 1996, 84, 405-414.
26. Dorhout-Mees, S.M.; Rinkel, G.J.; Feigin, V.L.; Algra, A.; den Bergh, W.M.; Vermeulen, M.; van Glin, J. Calcium antagonists for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst. Rev., 2007, CD000277.
27. Zhu, Y.H. Clinical study of nimodipine in preventing and treating cerebral vasospasm after subarachnoid hemorrhage. Chin. J. Prim. Med. Pharm, 2001, 8, 256-257.
28. Jennett, B.; Bond, M. Assessment of outcome after severe brain damage. Lancet, 1975, 1, 480-484.
29. Jadad, A.R.; Moore, R.A.; Carroll, D.; Jenkinson, C.; Reynolds, D.J.; Gavaghan, D.J.; McQuay, H.J. Assessing the quality of reports of randomized clinical trials, is blinding necessary. Control. Clin. Trials, 1996, 17, 1-12.
30. Lu, L.H.; Ren, Z.H.; Xiao, S.D. Calcium for preventing colorectal cancer and adenomatous polyps, a meta-analysis. Chin. J. Gastroenterol., 2007, 27, 178-181.
31. Hunt, W.E.; Hess, R.M. Surgical risk as related to time of intervention in the repair of intracranial aneurysms. J. Neurosurg., 1968, 28, 14-20.
32. Teasdale, G.; Jennett, B. Assessment of coma and impaired consciousness. A practical scale. Lancet, 1974, 2, 81-84.
33. Qureshi, A.I.; Sung, G.Y.; Razumovsky, A.Y.; Lane, K.; Straw, R.N.; Ulatowski, J.A. Early identification of patients at risk for symptomatic vasospasm after aneurysmal subarachnoid hemorrhage. Crit. Care Med., 2000, 28, 984-990.
34. Rosenthal, R. The "file drawer problem" and tolerance for null results. Psychol. Bull., 1979, 86, 638-641.
35. Cao, H.J.; Liu, J.P. Number needed to treat (NNT), an index for clinical therapeutic efficacy assessment-its significance and application. Chin. J. Integr. Tradit. West. Med., 2010, 30, 752-756.
36. Neil-Dwyer, G.; Mee, E.; Dorrance, D.; Lowe, D. Early intervention with nimodipine in subarachnoid haemorrhage. Eur. Heart J., 1987, 8(Suppl K), 41-47.
37. Kronvall, E.; Undren, P.; Romner, B.; Saveland, H.; Cronqvist, M.; Nilsson, O.G. Nimodipine in aneurysmal subarachnoid hemorrhage, a randomized study of intravenous or peroral administration. J. Neurosurg., 2009, 110, 58-63.
38. Mayberg, M.R.; Batjer, H.H.; Dacey, R.; Diringer, M.; Haley, E.C.; Heros, R.C.; Sternau, L.L.; Torner, J.; Adams, H.P., Jr.; Feinberg, W.; Thies, W. Guidelines for the management of aneurysmal subarachnoid hemorrhage. A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Circulation, 1994, 90, 2592-2605.
39. Bederson, J.B.; Connolly, E.S., Jr.; Batjer, H.H.; Dacey, R.G.; Dion, J.E.; Diringer, M.N.; Duldner, J.E., Jr.; Harbaugh, R.E.; Patel, A.B.; Rosenwasser, R.H. Guidelines for the management of aneurysmal subarachnoid hemorrhage, a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke, 2009, 40, 994-1025.
40. The Neurosurgery Section of Chinese Medical Association. Neurosurgical Expert Consensus on Prevention and Treatment of Cerebral Vasospasm. Chin. J. Stroke, 2008, 13, 356-362.
41. th July 2011] http://www.cochrane.org/training/cochrane-handbook
42. Moher, D.; Cook, D.J.; Eastwood, S.; Olkin, I.; Rennie, D.; Stroup, D.F. Improving the quality of reports of meta-analyses of randomised controlled trials, the QUOROM statement. Quality of Reporting of Meta-analyses. Lancet, 1999, 354, 1896-1900.
43. Saveland, H.; Ljunggren, B.; Brandt, L.; Messeter, K. Delayed ischemic deterioration in patients with early aneurysm operation and intravenous nimodipine. Neurosurgery, 1986, 18, 146-150.
44. Brandt, L.; Saveland, H.; Romner, B.; Ryman, T. Does nimodipine eliminate arterial hypertension as a prognostic risk factor in subarachnoid haemorrhage. Br. J. Neurosurg., 1991, 5, 485-489.
45. Popovic, E.A.; Danks, R.A.; Siu, K.H. Experience with nimodipine in aneurysmal subarachnoid haemorrhage. Med. J. Aust., 1993, 158, 91-94.
46. Mercier, P.; Alhayek, G.; Rizk, T.; Fournier, D.; Menei, P.; Guy, G. Are the calcium antagonists really useful in cerebral aneurysmal surgery? A retrospective study. Neurosurgery, 1994, 34, 30-36.
47. Pellettieri, L.; Bolander, H.; Carlsson, H.; Sjolander, U. Nimodipine treatment of selected good-risk patients with subarachnoid hemorrhage, no significant difference between present and historical results. Surg. Neurol., 1988, 30, 180-186.
48. Zhu, S.; Liu, X.; Li, Y.; Hou, Q.; Cai, P. Observation of therapeutic effect of combined nimodipine and magnesium sulphate after subarachnoid haemorrhage. Stroke Nerv. Dis., 1996, 3, 163.
49. Frerebeau, P.H.; Janny, P.; Taquoi, G.; Besson, G.; Buchheit, F.; Childs, M. Curative intravenous nimodipine treatment of subarachnoidal hemorrhage of vasospasm origine intracranial- aneurysms. Neurochirurgie, 1988, 34, 383-388.
50. Desbordes, J.M.; Ades, P.E.; Guggiari, M. Intravenous nimodipine in the treatment of cerebral vasospasm following subarachnoid hemorrhage caused by aneurysm rupture, a comparative multicenter study. Agressologie, 1989, 30, 438-440.
51. Islekel, S.; Oktar, N.; Yurtseven, T.; Ozdamar, N. Effect of nimodipine on the outcome of patients after aneurysm surgery. J. Neurol. Sci., 1999, 16, 4.
52. Maldonado, J.A.; Milchorena, G.; Lopez-Camacho, O.; Madrazo, I. Management with nimodipine of the cerebral vasospasm secondary to subarachnoid hemorrhage due to the rupture of an intracranial aneurysm. Arch. Invest. Med., 1990, 21, 179-187.
53. Wang, H.; Song, D.; Lu, J.; Jia, S. Preventive effect of nimodipine on SAH and CVS. J. Apopl. Nerv. Dis., 1995, 12, 237.
54. Gilsbach, J.M.; Reulen, H.J.; Ljunggren, B.; Brandt, L.; von HH, Mokry M, von Essen, C.; Conzen, M.A. Early aneurysm surgery and preventive therapy with intravenously administered nimodipine, a multicenter, double-blind, dose-comparison study. Neurosurgery, 1990, 26, 458-464.
55. Cabral, N.D.; Scaff, M. Use of nimodipine in spontaneous meningeal haemorrhage through aneurysm rupture. Rev. Bras. Neurol., 1991, 27, 21-22.
56. Xie, R.; Yao, J. Observation on the therapeutic effect of nimodipine versus kang-xuan-ding versus placebo for 14 days. J. Clin. Neurol., 1994, 7, 48-49.
57. Schmid-Elsaesser, R.; Kunz, M.; Zausinger, S.; Prueckner, S.; Briegel, J.; Steiger, H.J. Intravenous magnesium versus nimodipine in the treatment of patients with aneurysmal subarachnoid hemorrhage, a randomized study. Neurosurgery, 2006, 58, 1054-1065.
58. Zhao, J.Z.; Zhou, D.B.; Guo, J.; Ren, Z.Y.; Zhou, L.F.; Wang, S.; Xu, B.N.; Wang, R.Z. Effect of fasudil hydrochloride, a protein kinase inhibitor, on cerebral vasospasm and delayed cerebral ischemic symptoms after aneurysmal subarachnoid hemorrhage. Neurol. Med. Chir., 2006, 46, 421-428.