Efficacy of prophylactic nimodipine for delayed ischemic deficit after subarachnoid hemorrhage: A metaanalysis

Journal of Neurosurgery

Volumn 84, Issue 3, 1996, Pages 405-414

  Barker II, Fred G ^a   Ogilvy, Christopher S ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NONE

Author keywords

delayed ischemic deficit; metaanalysis; nimodipine; subarachnoid hemorrhage; vasospasm

Indexed keywords

NIMODIPINE;

ADULT; AGED; ARTICLE; BRAIN ISCHEMIA; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; HUMAN; MAJOR CLINICAL STUDY; META ANALYSIS; PRIORITY JOURNAL; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL; REGRESSION ANALYSIS; SUBARACHNOID HEMORRHAGE; TREATMENT OUTCOME; VASOSPASM;

EID: 0030030221     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.1996.84.3.0405     Document Type: Article

References (85)

1. Adams HP Jr: Calcium antagonists in the management of patients with aneurysmal subarachnoid hemorrhage: a review. Angiology 41:1010-1016, 1990
2. Agresti A: Categorical Data Analysis. New York: John Wiley & Sons, 1990
3. Allen GS, Ahn HS, Preziosi TJ, et al: Cerebral arterial spasm - a controlled trial of nimodipine in patients with subarachnoid hemorrhage. N Engl J Med 308:619-624, 1983
4. Anderson JL, Platia EV, Hallstrom A, et al: Interaction of baseline characteristics with the hazard of encainide, flecainide, and moricizine therapy in patients with myocardial infarction. A possible explanation for increased mortality in the Cardiac Arrhythmia Suppression Trial (CAST). Circulation 90: 2843-2852, 1994
5. Barker FG II: Efficacy of prophylactic antibiotics for craniotomy: a metaanalysis. Neurosurgery 35:484-492, 1994
6. Barker FG II, Heros RC: Clinical aspects of vasospasm. Neurosurg Clin North Am 1:277-288, 1990
7. Begg CB, Berlin JA: Publication bias: a problem in interpreting medical data. J R Stat Soc (A) 151:419-463, 1988
8. Berlin JA, Antman EM: Advantages and limitations of metaanalytic regressions of clinical trials data. Online J Curr Clin Trials 4:Doc No 134, 1994
9. Berlin JA, Laird NM, Sacks HS, et al: A comparison of statistical methods for combining event rates from clinical trials. Stat Med 8:141-151, 1989
10. Brand R, Kragt H: Importance of trends in the interpretation of an overall odds ratio in the meta-analysis of clinical trials. Stat Med 11:2077-2082, 1992
11. Brandt L, Säveland H, Romner B, et al: Does nimodipine eliminate arterial hypertension as a prognostic risk factor in subarachnoid haemorrhage? Br J Neurosurg 5:485-489, 1991
12. Cardiac Arrhythmia Pilot Study (CAPS) Investigators: Effects of encainide, flecainide, imipramine and moricizine on ventricular arrhythmias during the year after acute myocardial infarction: the CAPS. Am J Cardiol 61:501-509, 1988
13. Cardiac Arrhythmia Suppression Trial Investigators: Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. N Engl J Med 321:406-412, 1989
14. Chalmers TC: Problems induced by meta-analyses. Stat Med 10:971-980, 1991
15. Chyatte D, Fode NC, Sundt TM Jr: Early versus late intracranial aneurysm surgery in subarachnoid hemorrhage. J Neurosurg 69:326-331, 1988
16. Cochran WG: The combination of estimates from different experiments. Biometrics 10:101-129, 1954
17. Cook DJ, Sackett DL, Spitzer WO: Methodologic guidelines for systematic reviews of randomized control trials in health care from the Potsdam Consultation on Meta-Analysis. J Clin Epidemiol 48:167-171, 1995
18. Cook RJ, Sackett DL: The number needed to treat: a clinically useful measure of treatment effect. Br Med J 310:452-454, 1995
19. DerSimonian R, Laird N: Meta-analysis in clinical trials. Control Clin Trials 7:177-188, 1986
20. Desbordes JM, Ades PE, Guggiari M: Nimodipine intraveineuse dans le traitement curatif du vasospasme cérébral secondaire aux hémorragies méningées par rupture anévrysmale: étude comparative multicentrique. Agressologie 30:438-440, 1989
21. Di Mascio R, Marchioli R, Tognoni G: From pharmacological promises to controlled clinical trials to meta-analysis and back: the case of nimodipine in cerebrovascular disorders. Clin Trials Meta-Analysis 29:57-79, 1994
22. Dickersin K, Min YI: Publication bias: the problem that won't go away. Ann N Y Acad Sci 703:135-148, 1993
23. Dickersin K, Min YI, Meinert CL: Factors influencing publication of research results. Follow-up of applications submitted to two institutional review boards. JAMA 267:374-378, 1992
24. Dorsch NWC: A review of cerebral vasospasm in aneurysmal subarachnoid haemorrhage. Part II: Management. J Clin Neurosci 1:78-92, 1994
25. Dorsch NWC, King MT: A review of cerebral vasospasm in aneurysmal subarachnoid haemorrhage. Part I: Incidence and effects. J Clin Neurosci 1:19-26, 1994
26. Easterbrook PJ, Berlin JA, Gopalan R, et al: Publication bias in clinical research. Lancet 337:867-872, 1991
27. Echt DS, Liebson PR, Mitchell LB, et al: Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med 324:781-788, 1991
28. Eskridge JM, Newell DW, Winn HR: Endovascular treatment of vasospasm. Neurosurg Clin North Am 5:437-447, 1994
29. Felson DT: Bias in meta-analytic research. J Clin Epidemiol 45:885-892, 1992
30. Flamm ES, Adams HP Jr, Beck DW, et al: Dose-escalation study of intravenous nicardipine in patients with aneurysmal subarachnoid hemorrhage. J Neurosurg 68:393-400, 1988
31. Fleiss JL: Statistical Methods for Rates and Proportions, ed 2. New York: Wiley, 1981
32. Frerebeau P, Janny P, Taquoi G, et al: Traitement curatif du vasospasme des hémorragies méningées d'origine anévrysmale par la nimodipine intraveineuse. Etude coopérative multicentrique. Neurochirurgie 34:383-388, 1988
33. Fujita S, Kawaguchi T, Shose Y, et al: Flunarizine treatment in poor-grade aneurysm patients. Acta Neurochir 103:11-17, 1990
34. Gilsbach JM: Nimodipine in the prevention of ischaemic deficits after aneurysmal subarachnoid haemorrhage. An analysis of recent clinical studies. Acta Neurochir Suppl 45:41-50, 1988
35. Gilsbach JM, Reulen HJ, Ljunggren B, et al: Early aneurysm surgery and preventive therapy with intravenously administered nimodipine: a multicenter, double-blind, dose-comparison study. Neurosurgery 26:458-464, 1990
36. Haley EC Jr, Kassell NF, Alves WM, et al: Phase II trial of tirilazad in aneurysmal subarachnoid hemorrhage. A report of the Cooperative Aneurysm Study. J Neurosurg 82:786-790, 1995
37. Haley EC Jr, Kassell NF, Torner JC, et al: A randomized controlled trial of high-dose intravenous nicardipine in aneurysmal subarachnoid hemorrhage. A report of the Cooperative Aneurysm Study. J Neurosurg 78:537-547, 1993
38. Haley EC Jr, Kassell NF, Torner JC, et al: A randomized trial of nicardipine in subarachnoid hemorrhage: angiographic and transcranial Doppler ultrasound results. A report of the Cooperative Aneurysm Study. J Neurosurg 78:548-553, 1993
39. Han DH, Lee SH, Lee SH: Effect of nimodipine treatment on outcome in surgical cases of aneurysmal SAH. J Neurosurg 78:346A, 1993
40. Higashida RT, Halbach VV, Cahan LD, et al: Transluminal angioplasty for treatment of intracranial arterial vasospasm. J Neurosurg 71:648-653, 1989
41. Hongo K, Kobayashi S: Calcium antagonists for the treatment of vasospasm following subarachnoid haemorrhage. Neurol Res 15:218-224, 1993
42. Horner SM: Efficacy of intravenous magnesium in acute myocardial infarction in reducing arrhythmias and mortality. Meta-analysis of magnesium in acute myocardial infarction. Circulation 86:774-779, 1992
43. Hunt WE, Hess RM: Surgical risk as related to time of intervention in the repair of intracranial aneurysms. J Neurosurg 28:14-20, 1968
44. ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group: ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. Lancet 345:669-685, 1995
45. Jan M, Buchheit F, Tremoulet M: Therapeutic trial of intravenous nimodipine in patients with established cerebral vasospasm after rupture of intracranial aneurysms. Neurosurgery 23:154-157, 1988
46. Jennett B, Bond M: Assessment of outcome after severe brain damage. A practical scale. Lancet 1:480-484, 1975
47. Jones DR: Meta-analysis: weighing the evidence. Stat Med 14: 137-149, 1995
48. Kassell NF, Torner JC, Haley EC Jr, et al: The International Cooperative Study on the Timing of Aneurysm Surgery. Part 1: Overall management results. J Neurosurg 73:18-36, 1990
49. Langley MS, Sorkin EM: Nimodipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in cerebrovascular disease. Drugs 37:669-699, 1989
50. Mayberg MR, Batjer HH, Dacey R, et al: Guidelines for the management of aneurysmal subarachnoid hemorrhage. A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke 25: 2315-2328, 1994
51. Mee E, Dorrance D, Lowe D, et al: Controlled study of nimodipine in aneurysm patients treated early after subarachnoid hemorrhage. Neurosurgery 22:484-491, 1988
52. Mehta CR, Patel NR, Gray R: On computing an exact confidence interval for the common odds ratio in several 2 × 2 contingency tables. J Am Stat Assoc 80:969-973, 1985
53. Mercier P, Alhayek G, Rizk T, et al: Are the calcium antagonists really useful in cerebral aneurysmal surgery? A retrospective study. Neurosurgery 34:30-37, 1994
54. Mercier P, Alhayek G, Rizk T, et al: Are the calcium antagonists really useful in cerebral aneurysmal surgery? A retrospective study. Neurosurgery 35:542, 1994 (Letter)
55. Mercier P, Alhayek G, Rizk T, et al: Les anticalciques sont-ils réellement utiles en chirurgie anévrysmale cérébrale? Neurochirurgie 39:149-156, 1993
56. Messeter K, Brandt L, Ljunggren B, et al: Prediction and prevention of delayed ischemic dysfunction after aneurysmal subarachnoid hemorrhage and early operation. Neurosurgery 20: 548-553, 1987
57. Miyaoka M, Sato K, Ishii S: A clinical study of the relationship of timing to outcome of surgery for ruptured cerebral aneurysms. A retrospective analysis of 1622 cases. J Neurosurg 79: 373-378, 1993
58. Neil-Dwyer G, Mee E, Dorrance D, et al: Early intervention with nimodipine in subarachnoid haemorrhage. Eur Heart J 8 (Suppl K):41-47, 1987
59. Newell DW, Eskridge JM, Mayberg MR, et al: Angioplasty for the treatment of symptomatic vasospasm following subarachnoid hemorrhage. J Neurosurg 71:654-660, 1989
60. Öhman J, Heiskanen O: Effect of nimodipine on the outcome of patients after aneurysmal subarachnoid hemorrhage and surgery. J Neurosurg 69:683-686, 1988
61. Öhman J, Servo A, Heiskanen O: Long-term effects of nimodipine on cerebral infarcts and outcome after aneurysmal subarachnoid hemorrhage and surgery. J Neurosurg 74:8-13, 1991
62. Öhman J, Servo A, Heiskanen O: Risks factors for cerebral infarction in good-grade patients after aneurysmal subarachnoid hemorrhage and surgery: a prospective study. J Neurosurg 74:14-20, 1991
63. Olkin I: Meta-analysis: reconciling the results of independent studies. Stat Med 14:457-472, 1995
64. Origitano TC, Wascher TM, Reichman OH, et al: Sustained increased cerebral blood flow with prophylactic hypertensive hypervolemic hemodilution ("Triple-H") therapy after subarachnoid hemorrhage. Neurosurgery 27:729-740, 1990
65. Pellettieri L, Bolander H, Carlsson H, et al: Nimodipine treatment of selected good-risk patients with subarachnoid hemorrhage: no significant difference between present and historical results. Surg Neurol 30:180-186, 1988
66. Peroutka SJ, Banghart SB, Allen GS: Relative potency and selectivity of calcium antagonists used in the treatment of migraine. Headache 24:55-58, 1984
67. Petruk KC, West M, Mohr G, et al: Nimodipine treatment in poor-grade aneurysm patients. Results of a multicenter double-blind placebo-controlled trial. J Neurosurg 68:505-517, 1988
68. Philippon J, Grob R, Dagreou F, et al: Prevention of vasospasm in subarachnoid haemorrhage. A controlled study with nimodipine. Acta Neurochir 82:110-114, 1986
69. Pickard JD, Murray GD, Illingworth R, et al: Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial. Br Med J 298:636-642, 1989
70. Popovic EA, Danks RA, Siu KH: Experience with nimodipine in aneurysmal subarachnoid haemorrhage. Med J Aust 158: 91-94, 1993
71. Rosenthal R: The "file drawer problem" and tolerance for null results. Psychol Bull 86:638-641, 1979
72. Rousseaux P, Gomis P, Bazin A, et al: Comparaison de deux séries consécutives d'hemorragies méningées anévrysmales avec et sans nimodipine et étude de la courbe thermique. Neurochirurgie 39:157-165, 1993
73. Sekhar LN, Wechsler LR, Yonas H, et al: Value of transcranial Doppler examination in the diagnosis of cerebral vasospasm after subarachnoid hemorrhage. Neurosurgery 22:813-821, 1988
74. Senn S: Importance of trends in the interpretation of an overall odds ratio in the meta-analysis of clinical trials. Stat Med 13:293-296, 1994 (Letter)
75. Shibuya M, Suzuki Y, Sugita K, et al: Dose escalation trial of a novel calcium antagonist, AT877, in patients with aneurysmal subarachnoid haemorrhage. Acta Neurochir 107:11-15, 1990
76. Shibuya M, Suzuki Y, Sugita K, et al: Effect of AT877 on cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Results of a prospective placebo-controlled double-blind trial. J Neurosurg 76:571-577, 1992
77. Sprent P: Applied Nonparametric Statistical Methods, ed 2. London: Chapman & Hall, 1993
78. Sundt TM Jr, Kobayashi S, Fode NC, et al: Results and complications of surgical management of 809 intracranial aneurysms in 722 cases. Related and unrelated to grade of patient, type of aneurysm, and timing of surgery. J Neurosurg 56: 753-765, 1982
79. Takagi T, Kuwahara M, Nagai H, et al: [Effect of calcium antagonist (diltiazem) on symptomatic cerebral vasospasm.] Neurol Med Chir 26:863-869, 1986 (Jpn)
80. Teo KK, Yusuf S: Role of magnesium in reducing mortality in acute myocardial infarction. A review of the evidence. Drugs 46:347-359, 1993
81. Teo KK, Yusuf S, Collins R, et al: Effects of intravenous magnesium in suspected acute myocardial infarction: overview of randomised trials. Br Med J 303:1499-1503, 1991
82. Tettenborn D, Dycka J: Prevention and treatment of delayed ischemic dysfunction in patients with aneurysmal subarachnoid hemorrhage. Stroke 21 (Suppl IV):85-89, 1990
83. Thompson SG: Why sources of heterogeneity in meta-analysis should be investigated. Br Med J 309:1351-1355, 1994
84. Welty TE: Use of nimodipine for prevention and treatment of cerebral arterial spasm in patients with subarachnoid hemorrhage. Clin Pharmacol 6:940-946, 1987
85. Zelen M: The analysis of several 2×2 contingency tables. Biometrika 58:129-137, 1971