Effect of vasodilation by milrinone, a phosphodiesterase III inhibitor, on vasospastic arteries after a subarachnoid hemorrhage in vitro and in vivo: Effectiveness of cisternal injection of milrinone

Neurosurgery

Volumn 66, Issue 1, 2010, Pages 158-164

  Nishiguchi, Mitsuhisa ^a   Ono, Shigeki ^a   Iseda, Keiichi ^a   Manabe, Hiroaki ^a   Hishikawa, Tomohito ^a   Date, Isao ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Canine model; Intra arterial injection; Intracisternal injection; Milrinone; Vasospasm

Indexed keywords

MILRINONE; PHOSPHODIESTERASE III INHIBITOR;

ANGIOGRAPHY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY DIAMETER; ARTICLE; BASILAR ARTERY; BRAIN VASOSPASM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; SUBARACHNOID HEMORRHAGE; VASODILATATION;

ANGIOGRAPHY; ANIMALS; BASILAR ARTERY; CYCLIC AMP; DISEASE MODELS, ANIMAL; DOGS; FEMALE; INJECTIONS, INTRA-ARTERIAL; MALE; MILRINONE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; PHOSPHODIESTERASE INHIBITORS; SUBARACHNOID HEMORRHAGE; TIME FACTORS; VASODILATION; VASOSPASM, INTRACRANIAL;

EID: 77249090706     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000363153.62579.FF     Document Type: Article

References (15)

1. Honerjäger P. Pharmacology of bipyridine phosphodiesterase III inhibitors. Am Heart J. 1991;121(6 Pt 2):1939-1944.
2. Arakawa Y, Kikuta K, Hojo M, Goto Y, Ishii A, Yamagata S. Milrinone for the treatment of cerebral vasospasm after subarachnoid hemorrhage: report of seven cases. Neurosurgery. 2001;48(4):723-728.
3. Arakawa Y, Kikuta K, Hojo M, et al. Milrinone reduces cerebral vasospasm after subarachnoid hemorrhage of WFNS Grade IV or V. Neurol Med Chir (Tokyo). 2004;44(8):393-400.
4. Khajavi K, Ayzman I, Shearer D, et al. Prevention of chronic cerebral vasospasm in dogs with milrinone. Neurosurgery. 1997;40(2):354-362.
5. Varsos VG, Liszczak TM, Han DH, et al. Delayed cerebral vasospasm is not reversible by aminophylline, nifedipine, or papaverine in a "two- hemorrhage" canine model. J Neurosurg. 1983;58(1):11-17.
6. Kimura H, Sasaki K, Megro T, Zhang JH. Phosphatidylinositol 3-kinase inhibitor failed to reduce cerebral vasospasm in dog model of experimental subarachnoid hemorrhage. Stroke. 2002;33(2):593-599.
7. Mustafa S, Thulesius O. Cooling-induced carotid artery dilatation: an experimental study in isolated vessels. Stroke. 2002;33(1):256-260.
8. Onoue H, Tsutsui M, Smith L, Stelter A, O'Brien T, Katusic ZS. Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery after experimental subarachnoid hemorrhage. Stroke. 1998;29(9):1959-1966.
9. Stoodley M, Weihl CC, Zhang Z, et al. Effect of adenovirus-mediated nitric oxide synthase gene transfer on vasospasm after experimental subarachnoid hemorrhage. Neurosurgery. 2000;46(5):1193-1203.
10. Zubkov AY, Rollins KS, McGehee B, Parent AD, Zhang JH. Relaxant effect of U0126 in hemolysate-, oxyhemoglobin-, and bloody cerebrospinal fluid-induced contraction in rabbit basilar artery. Stroke. 2001;32(1):154-161.
11. Monrad ES, Baim DS, Smith HS, Lanoue AS. Milrinone, dobutamine, and nitroprusside: comparative effects on hemodynamics and myocardial energetics in patients with severe congestive heart failure. Circulation. 1986;73(3 Pt 2):III168-III174.
12. Anderson JL. Hemodynamic and clinical benefits with intravenous milrinone in severe chronic heart failure: results of a multicenter study in the United States. Am Heart J. 1991;121(6 Pt 2):1956-1964.
13. Awad IA, Carter LP, Spetzler RF, Medina M, Williams FC Jr. Clinical vasospasm after subarachnoid hemorrhage: response to hypervolemic hemodilution and hypertension. Stroke. 1987;18(2):365-372.
14. Stroshane RM, Koss RF, Biddlecome CE, Luczkowec C, Edelson J. Oral and intravenous pharmacokinetics of milrinone in human volunteers. J Pharm Sci. 1984;73(10):1438-1441.
15. Kodama N, Sasaki T, Kawatani M, Sato M, Asari J. Cisternal irrigation therapy with urokinase and ascorbic acid for prevention of vasospasm after aneurismal subarachnoid hemorrhage. Outcome in 217 patients. Surg Neurol. 2000;53(2):110-118.