Polymorphism in the KCNA3 gene is associated with susceptibility to autoimmune pancreatitis in the Japanese population

Disease Markers

Volumn 31, Issue 4, 2011, Pages 223-229

  Ota, Masao ^a   Ito, Tetsuya ^a   Umemura, Takeji ^a   Katsuyama, Yoshihiko ^a   Yoshizawa, Kaname ^a   Hamano, Hideaki ^a   Kawa, Shigeyuki ^b  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHINSHU UNIVERSITY   (Japan)

Author keywords

AIP; autoimmune pancreatitis; disease susceptibility; KCNA3; SNPs

Indexed keywords

POTASSIUM CHANNEL KV1.3;

ADULT; AGED; ARTICLE; AUTOIMMUNE PANCREATITIS; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOME ANALYSIS; GENOTYPE; HUMAN; JAPANESE; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE MARKER; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 81055144317     PISSN: 02780240     EISSN: 18758630     Source Type: Journal    
DOI: 10.3233/DMA-2011-0820     Document Type: Article

References (34)

1. H. Sarles, J.C. Sarles, R.Muratore et al., Chronic inflammatory sclerosis of the pancreas-an autonomous pancreatic disease Am J Dig Dis 6 (1961), 688-698.
2. K. Kawaguchi, M. Koike, K. Tsuruta et al., Lymphoplasmacytic sclerosing pancreatitis with cholangitis: a variant of primary sclerosing cholangitis extensively involving pancreas, Hum Pathol 22 (1991), 387-395.
3. K. Yoshida, F. Toki, T. Takeuchi et al., Chronic pancreatitis caused by an autoimmune abnormality, proposal of the concept of autoimmune pancreatitis, Dig Dis Sci 40 (1995), 1561-1568.
4. K. Horiuchi, S. Kawa, T. Akamatsu et al., Characteristic pancreatic duct appearance in autoimmune chronic pancreatitis: a case report and review of the Japanese literature, Am J Gastroenterol 93 (1998), 260-263. (Pubitemid 29063980)
5. G.W. Erkelens, F.P Vleggaar, W. Lesterhuis et al., Sclerosing pancreatico-cholangitis responsive to steroid therapy, Lancet 354 (1999), 43-44. (Pubitemid 29304304)
6. H. Hamano, S. Kawa, A. Horiuchi et al., High serum IgG4 concentrations in patients with sclerosing pancreatitis, New Engl J Med 344 (2001), 732-738. (Pubitemid 32204991)
7. H. Hamano, S. Kawa, Y. Ochi et al., Hydronephrosis associated with retroperitoneal fibrosis and sclerosing pancreatitis, Lancet 359 (2002), 1403-1404. (Pubitemid 34442382)
8. T. Kamisawa, N. Egawa, H. Nakajima et al., Clinical difficulties in the differentiation of autoimmune pancreatitis and pancreatic carcinoma, Am J Gastroenterol 98 (2003), 2694-2699. (Pubitemid 38020110)
9. T. Kamisawa, N. Funata, Y. Hayashi et al., Close relationship between autoimmune pancreatitis and multifocal fibrosclerosis, Gut 52 (2003), 683-687. (Pubitemid 36528870)
10. H. Saegusa, M. Momose, S. Kawa et al., Hilar and pancreatic gallium-67 accumulation is characteristic feature of autoimmune pancreatitis, Pancreas 27 (2003), 20-25. (Pubitemid 36775974)
11. K. Komatsu, H. Hamano and Y. Ochi et al., High Prevalence of Hypothyroidism in Patients with Autoimmune Pancreatitis, Dig Dis Sci 50 (2005), 1052-1057. (Pubitemid 40864006)
12. K. Taniguchi, M. Ko, S. Seko et al., Interstitial pneumonia associated with autoimmune pancreatitis, Gut 70 (2004), 770.
13. S. Takeda, J. Haratake, T. Kasai et al., IgG4-associated idiopathic tubulointerstitial nephritis complicating autoimmune pancreatitis, Nephrol Dial Transplant 19 (2004), 474-476. (Pubitemid 38196002)
14. K. Okazaki, K. Uchida, M. Ohana et al., Autoimmune-related pancreatitis is associated with autoantibodies and Th1/Th2- type cellular immune response, Gastroenterology 118 (2000), 573-581. (Pubitemid 30140856)
15. K. Okazaki, K. Uchida and T. Chiba, Recent concept of autoimmune-related pancreatitis, J Gastroenterol 36 (2001), 293-302. (Pubitemid 32515075)
16. T. Umemura, Y. Zen, H. Hamano et al., Immunoglobin G4- hepatopathy: association of immunoglobin G4-bearing plasma cells in liver with autoimmune pancreatitis, Hepatology 46 (2007), 463-471. (Pubitemid 47344782)
17. S. Kawa, M. Ota, K. Yoshizawa et al., HLA DRB10405- DQB10401 haplotype is associated with autoimmune pancreatitis in the Japanese population, Gastroenterology 122 (2002), 1264-1269. (Pubitemid 34465169)
18. T. Umemura, M. Ota, H. Hamano et al., Genetic association of Fc receptor-like 3 polymorphisms with autoimmune pancreatitis in Japanese patients, Gut 55 (2006), 1367-1368. (Pubitemid 44277378)
19. T.Umemura,M.Ota, H.Hamano et al., Association of autoimmune pancreatitis with cytotoxic T-lymphocyte antigen 4 gene polymorphisms in Japanese patients, Am J Gastroenterol 103 (2008), 588-594. (Pubitemid 351406007)
20. K. Okazaki, S. Kawa, T. Kamisawa et al., Research Committee of Intractable Diseases of the Pancreas. Clinical diagnostic criteria of autoimmune pancreatitis: revised proposal, J Gastroenterol 41 (2006), 626-631. (Pubitemid 44288525)
21. H. Hamano, N. Arakura, T. Muraki et al., Prevalence and distribution of extrapancreatic lesions complicating autoimmune pancreatitis, J Gastroenterol 41 (2006), 1197-1205. (Pubitemid 46487210)
22. S.B. Gabriel, S.F. Schaffner, H. Nguyen et al., The structure of haplotype blocks in the human genome, Science 296 (2002), 2225-2229. (Pubitemid 34680308)
23. J.C. Barrett, B. Fry, J. Maller et al., Haploview: Analysis and visualization of LD and haplotype maps, Bioinformatics 21 (2005), 263-265. (Pubitemid 40202029)
24. S. Kawa, K. Kitahara, H. Hamano et al., A novel immunoglobulin- immunoglobulin interaction in autoimmunity, PLoS ONE 3 (2008), e1637.
25. L.R. Cardon and J.I. Bell, Association study designs for complex diseases, Nat Rev Genet 2 (2001), 91-99. (Pubitemid 33674000)
26. G. Tamiya,M. Shinya, T. Imanishi et al.,Whole genome association study of rheumatoid arthritis using 27039 microsatellites, Hum Mol Genet 14 (2005), 2305-2321. (Pubitemid 41417994)
27. K. Folander, L. Douglass and R. Swanson, Confirmation of the assignment of the gene encoding Kv1.3, a voltage-gated potassium channel (KCNA3) to the proximal short arm of human chromosome 1, Genomics 23 (1994), 295-296. (Pubitemid 24296976)
28. G.C.Koo, J.T. Blake, A.Talento et al., Blockade of the voltagegated potassium channel Kv1.3 inhibits immune responses in vivo, J Immunol 158 (1997), 5120-5128. (Pubitemid 127681213)
29. C.M. Fanger, H. Rauer, A.L. Neben et al., Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels, J Biol Chem 276 (2001), 12249-12256.
30. O. Tschritter, F.Machicao, N. Stefan et al., Anewvariant in the human Kv1.3 gene is associated with low insulin sensitivity and impaired glucose tolerance, J Clin Endocrinol Metab 60 (2006), 734-739.
31. M. Levite, L. Cahalon, A. Peretz et al., Extracellular K(+) and opening of voltage-gated potassium channels activated T cell integrin function:physical and functional association between Kv1.3 and beta 1 integrins, JExpMed 191 (2000), 1167-1176. (Pubitemid 30207679)
32. C. Beeton, H.Wulff, N.E. Standifer et al., Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune disease, Proc Natl Acad Sci 103 (2006), 17414-17419. (Pubitemid 44788983)
33. H. Wulff, H.G. Knaus, M. Pennington et al., K+ channel expression during B cell differentiation:implications for immunomodulation and autoimmunity, J Immunol 173 (2004), 776-786. (Pubitemid 38924252)
34. O. Tschritter, F.Machicao, N. Stefan et al., Anewvariant in the human Kv1.3 gene is associated with low insulin sensitivity and impaired glucose tolerance, J Clin Endocrinol Metab 91 (2006), 654-658. (Pubitemid 43236939)