Apocynin attenuates ventilator-induced lung injury in an isolated and perfused rat lung model

Intensive Care Medicine

Volumn 37, Issue 8, 2011, Pages 1360-1367

  Chiang, Chi Huei ^a,b   Chuang, Chiao Hui ^a   Liu, Shiou Ling ^a   Lee, Tzong Shyuan ^b   Kou, Yu Ru ^b   Zhang, Haibo ^c,d,e  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c ST MICHAEL'S HOSPITAL   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

ARDS; Inflammation; MAPK; NADPH; NF B

Indexed keywords

APOCYNIN; CARBONYL DERIVATIVE; CASPASE 3; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOPEROXIDASE; STRESS ACTIVATED PROTEIN KINASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ARTIFICIAL VENTILATION; ATTENUATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; INFLAMMATION; LUNG HEMODYNAMICS; LUNG LAVAGE; LUNG PARENCHYMA; LUNG PERFUSION; LUNG WEIGHT; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; TIDAL VOLUME; VENTILATOR INDUCED LUNG INJURY;

ACETOPHENONES; ANALYSIS OF VARIANCE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; DISEASE MODELS, ANIMAL; LUNG; RATS; REACTIVE OXYGEN SPECIES; TIDAL VOLUME; VENTILATOR-INDUCED LUNG INJURY;

EID: 80955180996     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-011-2251-z     Document Type: Article

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