Antioxidant enzymes are induced during recovery from acute lung injury

Critical Care Medicine

Volumn 28, Issue 7, 2000, Pages 2486-2491

  Kozar, Rosemary A ^a   Weibel, Christopher J ^b   Cipolla, James ^b   Klein, Andrew J P ^b   Abedin, Mohammed Z ^b   Trooskin, Stanley Z ^b   Haber, Marion M ^b  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Acute lung injury; Acute respiratory distress syndrome; Antioxidant; Free radicals; Glutathione; Hexose monophosphate shunt; Phorbol myristate acetate

Indexed keywords

ANTIOXIDANT; FREE RADICAL; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE PEROXIDASE; HEXOSE PHOSPHATE; LUNG ENZYME; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOGLUCONATE DEHYDROGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CONVALESCENCE; DISEASE COURSE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INDUCTION; GLUTATHIONE METABOLISM; HEXOSE MONOPHOSPHATE SHUNT; HISTOPATHOLOGY; LUNG FUNCTION; LUNG INJURY; LUNG LAVAGE; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RABBIT; RESPIRATORY DISTRESS SYNDROME; SCORING SYSTEM;

EID: 0033859818     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200007000-00050     Document Type: Article

References (37)

1. 1. Fulkerson WJ, MacIntyre N, Stamler J, et al: Pathogenesis and treatment of adult respiratory distress syndrome. Arch Intern Med 1996; 156:29-38
2. 2. Cochrane G, Spragg R, Revak S: Studies on the pathogenesis of the adult respiratory distress syndrome: Evidence of oxidant activity in bronchial alveolar lavage fluid. J Clin Invest 1983; 71:754-761
3. 3. Chabot F, Mitchell JS, Gutteridge JM, et al: Reactive oxygen species in acute lung injury. Eur Respir J 1998; 11:745-757
4. 4. Tagan MC, Market M, Schaller MD, et al: Oxidative metabolism of circulating granulocytes in adult respiratory distress syndrome. Am J Med 1991; 91:725-785
5. 5. Davreux CJ, Soric I, Nathens AB, et al: N-acetyl cysteine attenuates acute lung injury in the rat. Shock 1997; 8:432-438
6. 6. Goodman RB, Streiter RM, Martin DP, et al: Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome. Am J Respir Crit Care Med 1996; 154(3 Pt 1):602-611
7. 7. Strieter RM, Kunkel SL: Acute lung injury: The role of cytokines in the elicitation of neutrophils. J Invest Med 1994; 42:640-651
8. 8. Shasby DM, Vanbenthuysen KA, Tate RM, et al: Granulocytes mediate acute edematous lung injury in rabbits and in isolated rabbit lungs perfused with phorbol myristate acetate: Role of oxygen radicals. Am Rev Respir Dis 1982; 125:443-447
9. 9. Kurfoda M, Murakami K, Ishikawa Y: Role of hydroxyl radicals derived from granulocytes in lung injury induced by phorbol myristate acetate. Am Rev Respir Dis 1987; 136: 1435-1444
10. 10. McCall CE, Taylor RG, Cousart SL, et al: Pulmonary injury induced by phorbol myristate acetate following intravenous administration in rabbits. Am J Pathol 1983; 111: 258-262
11. 11. Bardales RH, Xie SS, Schaefer RF, et al: Apoptosis is a major pathway responsible for the resolution of type II pneumocytes in acute lung injury. Am J Pathol 1996; 149: 845-852
12. 12. Kollef MH, Schuster DP: The acute respiratory distress syndrome. N Engl J Med 1995; 332:27-37
13. 13. Kletzein RF, Harris PR, Foellmi LA: Glucose-6-phosphate dehydrogenase: A housekeeping enzyme subject to tissue-specific regulation by hormones, nutrients, and oxidant stress. FASEB J 1994; 8:174-181
14. 14. Pandolfi PP, Sonati F, Rivi R, et al: Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress. EMBO J 1995; 14:5209-5215
15. 15. Zimniak L, Awasthi S, Srivastava SK: Increased resistance to oxidative stress in transfected cultured cells over expressing glutathione S-transferase mGSTA4-4. Toxicol Appl Pharmacol 1997; 143:221-229
16. 16. Chow CK, Tappel AL: An enzymatic protective mechanism against lipid peroxidation damage to lungs of ozone-exposed rats. Lipids 1972; 7:518-524
17. 17. Tierney D, Ayers L, Herza S, et al: Pentose pathway and production of reduced nicotinamide adenine dinucleotide phosphate. A mechanism that may protect lungs from oxidants. Am Rev Respir Dis 1973; 108: 1348-1351
18. 18. White CW, Ghezzi P, Dinarello SA, et al: Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia. J Clin Invest 1987; 79:1868-1873
19. 19. Kimball RE, Reddy K, Peirce TH, et al: Oxygen toxicity: Augmentation of antioxidant defense mechanisms in rat lung. Am J Physiol 1976; 230:1425-1431
20. 20. Knickelbein RG, Ingbar DH, Seres T, et al: Hyperoxia enhances expression of ã-glutamyl transpeptidase and increases protein S-glutathiolation in rat lung. Am J Physiol 1996; 270(1 Pt 1):L115-L121
21. 21. White CW, Ghezzi P, McMahon S, et al: Cytokines increase rat lung antioxidant enzymes during exposure to hyperoxia. J Appl Physiol 1989; 66:1003-1007
22. 22. Lorry OH, Rosebrough NJ, Farr AL, et al: Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193:265-275
23. 23. Doumas BT, Watson WA, Briggs HG: Albumin standards and the measurement of serum albumin with bromcresol green. Clin Chim Acta 1971; 31:87-96
24. 24. Glock GE, MacLean F: Further studies on the properties of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase of rat liver. Biochem J 1953; 55: 400-408
25. 25. Horn D: Glutathione reductase. In: Methods of Enzymatic Analysis. Bergmeyer HU (Ed). New York, Academic Press, 1963, pp. 876-877
26. 26. Little C, O'Brian PJ: An intracellular GSH peroxidase with a lipid peroxidase substrate. Biochem Biophys Res Commun 1968; 31: 145-150
27. 27. Mikulaschek A, Trooskin SZ, Winfield J, et al: Pulmonary fibroblast function in an acute lung injury model. J Trauma 1995; 39:59-66
28. 28. White CW, Mimmack RF, Repine JE: Accumulation of lung tissue. Oxidized glutathione (GSSG) as a marker of oxidant induced lung injury. Chest 1986; 89:111S-113S
29. 29. Domenici-Lombardo L, Adembri C, Consalvo M, et al: Evolution of endotoxin induced acute lung injury in the rat. Int J Exp Pathol 1995; 76:381-390
30. 30. Kennedy KA: Effect of hyperoxia on antioxidants in neonatal rat type II cells in vitro and in vivo. Pediatr Res 1989; 26:400-403
31. 31. Brandes ME, Finkelstein JN: Stimulated rabbit alveolar macrophages secrete a growth factor for type II pneumocytes. Am J Respir Cell Mol Biol 1989; 1:101-109
32. 32. Winfield JP, Trooskin SZ, Mikulaschek AW, et al: Alveolar macrophages stimulate surfactant secretion by the lung cells. Surg Forum 1992; 43:62-63
33. 33. Gadek JE, Pacht ER: The interdependence of lung antioxidants and antiprotease defense in ARDS. Chest 1996; 110:273S-277S
34. 34. Gillissen A, Nowak D: Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy. Respir Med 1998; 92: 609-623
35. 35. Bernard GR, Wheeler AP, Arons MM, et al: A trial of anti-oxidants N-acetyl cysteine and procysteine in ARDS. The Antioxidant in ARDS Study Group. Chest 1997; 112: 164-172
36. 36. Buhl R, Meyer A, Vogelmeier C: Oxidant-protease interaction in the lung. Prospects for antioxidant therapy. Chest 1996; 110: 267S-272S
37. 37. Laurent T, Markert M, Feihl F, et al: Oxidant-antioxidant balance in granulocytes during ARDS. Effect of N-acetyl cysteine. Chest 1996; 109:163-166