Research in practice: Antimicrobial peptides of the skin;Forschen für die Praxis: Antimikrobielle Peptide der Haut

JDDG - Journal of the German Society of Dermatology

Volumn 9, Issue 9, 2011, Pages 678-680

  Gläser, Regine ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

antimicrobial peptides; bacterial infection; barrier; immunity; keratinocyte

Indexed keywords

BETA DEFENSIN; POLYPEPTIDE ANTIBIOTIC AGENT; PSORIASIN; RIBONUCLEASE; RIBONUCLEASE 7; UNCLASSIFIED DRUG;

ATOPIC DERMATITIS; BACTERIAL COLONIZATION; ESCHERICHIA COLI; HUMAN; NONHUMAN; PSORIASIS; PSORIASIS VULGARIS; REVIEW; SKIN INFECTION; SKIN PROTECTION; STAPHYLOCOCCUS AUREUS; ULTRAVIOLET B RADIATION;

EID: 80955180933     PISSN: 16100379     EISSN: 16100387     Source Type: Journal    
DOI: 10.1111/j.1610-0387.2011.07708.x     Document Type: Review

References (12)

1. Henseler T, Christophers E,. Disease concomitance in psoriasis. J Am Acad Dermatol 1995; 32: 982-6.
2. Harder J, Bartels J, Christophers E, Schröder JM,. A peptide antibiotic from human skin. Nature 1997; 387: 861.
3. Harder J, Bartels J, Christophers E, Schröder JM,. Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic. J Biol Chem 2001; 276: 5707-13.
4. Harder J, Schröder JM,. RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin. J Biol Chem 2002; 277: 46779-84. (Pubitemid 35417681)
5. Gläser R, Harder J, Lange H, Bartels J, Christophers E, Schröder JM,. Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection. Nat Immunol 2005; 6: 57-64.
6. Simanski M, Dressel S, Gläser R, Harder J,. RNase 7 protects healthy skin from Staphylococcus aureus colonization. J Invest Dermatol 2010; 130: 2836-8.
7. Abtin A, Eckhart L, Mildner M, Gruber F, Schröder JM, Tschachler E,. Flagellin is the principal inducer of the antimicrobial peptide S100A7c (psoriasin) in human epidermal keratinocytes exposed to Escherichia coli. Faseb J 2008; 22: 2168-76. (Pubitemid 351948636)
8. Gläser R, Meyer-Hoffert U, Harder J, Cordes J, Wittersheim M, Kobliakova J, Fölster-Holst R, Proksch E, Schröder JM, Schwarz T,. The antimicrobial protein psoriasin (S100A7) is upregulated in atopic dermatitis and after experimental skin barrier disruption. J Invest Dermatol 2009; 129: 641-9.
9. Harder J, Dressel S, Wittersheim M, Cordes J, Meyer-Hoffert U, Mrowietz U, Fölster-Holst R, Proksch E, Schrö-der JM, Schwarz T, Gläser R,. Enhanced expression and secretion of antimicrobial peptides in atopic dermatitis and after superficial skin injury. J Invest Dermatol 2010; 130: 1355-64.
10. Dressel S, Harder J, Cordes J, Witters-heim M, Meyer-Hoffert U, Sunderköt-ter C, Gläser R,. Differential expression of antimicrobial peptides in margins of chronic wounds. Exp Dermatol 2010; 19: 628-32.
11. Gläser R, Navid F, Schuller W, Jant-schitsch C, Harder J, Schröder JM, Schwarz A, Schwarz T,. UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo. J Allergy Clin Immunol 2009; 123: 1117-23.
12. Köten B, Simanski M, Gläser R, Pod-schun R, Schröder JM, Harder J,. RNase 7 contributes to the cutaneous defense against Enterococcus faecium. PLoS One 2009; 4: e6424.