Anti-tumoral activities of dioncoquinones B and C and related naphthoquinones gained from total synthesis or isolation from plants

European Journal of Medicinal Chemistry

Volumn 46, Issue 12, 2011, Pages 5778-5789

  Bringmann, Gerhard ^a   Zhang, Guoliang ^a   Hager, Anastasia ^a,c   Moos, Michael ^a   Irmer, Andreas ^a   Bargou, Ralf ^b   Chatterjee, Manik ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b Hospital of Würzburg   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Antitumor activity; Dioncoquinones A E; Multiple myeloma; Naphthoquinones; Triphyophyllum peltatum

Indexed keywords

3 HYDROXY 5,6 DIMETHOXY 2 METHYL 1,4 NAPHTHOQUINONE; 3 HYDROXY 5,6,7 TRIMETHOXY 2 METHYL 1,4 NAPHTHOQUINONE; 3,5,6 TRIHYDROXY 2 METHYL 1,4 NAPHTHOQUINONE; 3,5,6 TRIHYDROXY 7 METHOXY 2 METHYL 1,4 NAPHTHOQUINONE; 3,5,6,7 TETRAHYDROXY 2 METHYL 1,4 NAPHTHOQUINONE; 4 (2' BROMO 4',5' DIMETHOXYPHENYL) 3 METHOXYCARBONYL 3 BUTENOIC ACID; 5 METHOXY 2 METHYL 4 NAPHTHOL; 5,6 DIMETHOXY 2 METHYL 1,2 NAPHTHOQUINONE; 5,6 DIMETHOXY 2 METHYL 1,4 NAPHTHOQUINONE; 5,6 DIMETHOXY 2 METHYL 4 NAPHTHOL; 5,6,7 TRIMETHOXY 2 METHYL 1,2 NAPHTHOQUINONE; 5,6,7 TRIMETHOXY 2 METHYL 1,4 NAPHTHOQUINONE; 5,6,7 TRIMETHOXY 2 METHYL 4 NAPHTHOL; 8 HYDROXYDROSERONE; ANTINEOPLASTIC AGENT; DIONCOQUINONE A; DIONCOQUINONE D; DIONCOQUINONE E; DROSERONE; MELPHALAN; METHYL 4 ACETOXY 8 BROMO 5,6 DIMETHOXY 2 NAPHTHOATE; METHYL 4 HYDROXY 5,6 DIMETHOXY 2 NAPHTHOATE; N,N DIETHYL 2,3 DIMETHOXY 6 (2 METHYLALLYL)BENZAMIDE; N,N DIETHYL 2,3 DIMETHOXYBENZAMIDE; N,N DIETHYL 2,3,4 TRIMETHOXY 6 (2 METHYLALLYL)BENZAMIDE; N,N DIETHYL 2,3,4 TRIMETHOXYBENZAMIDE; NAPHTHOQUINONE; PLUMBAGIN; QUINONE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DIONCOPHYLLACEAE; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MEDICINAL PLANT; PLANT CELL CULTURE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; TRIPHYOPHYLLUM PELTATUM;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; DIONCOPHYLLACEAE; HUMANS; MULTIPLE MYELOMA; NAPHTHOQUINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80955136642     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.09.012     Document Type: Article

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