Biosynthesis of naphthylisoquinoline alkaloids: synthesis and incorporation of an advanced 13C2-labeled isoquinoline precursor

Tetrahedron

Volumn 63, Issue 8, 2007, Pages 1755-1761

  Bringmann, Gerhard ^a   Mutanyatta Comar, Joan ^a   Greb, Marco ^a   Rüdenauer, Stefan ^a   Noll, Torsten F ^a   Irmer, Andreas ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

13C2 labeling; Biosynthesis; Dioncophylline A; Naphthylisoquinoline alkaloids; Triphyophyllum peltatum

Indexed keywords

ALKALOID DERIVATIVE; CARBON 13; DIONCOPHYLLINE A; HYDROGEN; ISOQUINOLINE DERIVATIVE; TETRAHYDROISOQUINOLINE DERIVATIVE;

ARTICLE; CALLUS CULTURE; DRUG LABELING; DRUG SYNTHESIS; MEDICINAL PLANT; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SPECTROSCOPY; TRIPHYOPHYLLUM PELTATUM;

TRIPHYOPHYLLUM PELTATUM;

EID: 33846222797     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2006.12.022     Document Type: Article

References (32)

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21. The initially observed formation of the respective O,N-bistriflated compound as an undesired byproduct was avoided by first diluting the triflic anhydride, see Section 4.
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31. 19 value is for the non-labeled analog.
32. 19 value is only given for the hydrobromide.