Reg IV protein and mRNA expression in different rat organs

Acta Histochemica

Volumn 113, Issue 8, 2011, Pages 793-797

  Azman, Josip ^a   Starcevic Klasan, Gordana ^b   Ivanac, Danijel ^b   Picard, Anne ^c   Jurisic Erzen, Dubravka ^a   Nikolic, Marina ^b   Malnar, Daniela ^b   Arbanas, Juraj ^b   Jerkovic, Romana ^b  

^a KBC RIJEKA   (Croatia)

^b UNIVERSITY OF RIJEKA   (Croatia)

^c UNIVERSITY OF PADOVA   (Italy)

Author keywords

Gene expression; Immunohistochemistry; Rat; Reg IV; Western blot

Indexed keywords

GROWTH FACTOR; MESSENGER RNA; REGENERATING IV PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; REGENERATING IV GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRUCTURE ACTIVITY RELATION; TISSUE DISTRIBUTION; WESTERN BLOTTING;

ANIMALS; ANTIGENS, NEOPLASM; CELL PROLIFERATION; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; LECTINS, C-TYPE; MALE; ORGAN SPECIFICITY; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL;

RATTUS; RATTUS NORVEGICUS;

EID: 80855136454     PISSN: 00651281     EISSN: 16180372     Source Type: Journal    
DOI: 10.1016/j.acthis.2010.11.008     Document Type: Article

References (30)

1. Baskin L.S., Hayward S.W., Sutherland R.A., DiSandro M.S., Thomson A.A., Cunha G.R. Cellular signaling in the bladder. Front Biosci 1997, 2:592-595.
2. Bishnupuri K.S., Luo Q., Murmu N., Houchen C.W., Anant S., Dieckgraefe B.K. Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas. Gastroenterology 2006, 130:137-149.
3. De la Monte S.M., Ozturk M., Wands J.R. Enhanced expression of a pancreatic protein in Alzheimer′s disease and the developing human brain. J Clin Invest 1990, 86:1004-1010.
4. Gobé G., Zhang X.J., Willgoss D.A., Schoch E., Hogg N.A., Endre Z.H. Relationship between expression of Bcl-2 genes and growth factors in ischemic acute renal failure in the rat. J Am Soc Nephrol 2000, 11:454-467.
5. Gu Z., Rubin M.A., Yang Y., Deprimo S.E., Zhao H., Horvath S., et al. A promising marker of hormone refractory metastatic prostate cancer. Clin Cancer Res 2005, 11:2237-2243.
6. Hartupee J.C., Zhang H., Bonaldo M.F., Soares M.B., Dieckgraefe B.K. Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV. Biochim Biophys Acta 2001, 1518:287-293.
7. Holdsworth R.J. Regeneration of the spleen and splenic autotransplantation. Br J Surg 1991, 78:270-278.
8. Kämäräinen M., Heiskala K., Knuutila S., Heiskala M., Winqvist O., Andersson L.C. RELP, a novel human reg-like protein with up-regulated expression in inflammatory and metaplastic gastrointestinal mucosa. Am J Pathol 2003, 163:11-20.
9. Kodama S., Kühtreiber W., Fujimura S., Dale E.A., Faustman D.L. Islet regeneration during the reversal of autoimmune diabetes in NOD mice. Science 2003, 302:1223-1227.
10. Lasserre C., Colnot C., Brechot C., Poirier F. HIP/PAP gene, encoding a C-type lectin overexpressed in primary liver cancer, is expressed in nervous system as well as in intestine and pancreas of the postimplantation mouse embryo. Am J Pathol 1999, 154:1601-1610.
11. Livesey F.J., O' Brien J.A., Li M., Smith A.G., Murphy L.J., Hunt S.P. A Schwann cell mitogen accompanying regeneration of motor neurons. Nature 1997, 390:614-618.
12. Lonyai A., Kodama S., Burger D., Davis M., Faustman D.L. The promise of Hox11+ stem cells of the spleen for treating autoimmune diseases. Horm Metab Res 2008, 40:137-146.
13. Mitani Y., Oue N., Matsumura S., Yoshida K., Noguchi T., Ito M., et al. Reg IV is a serum biomarker for gastric cancer patients and predicts response to 5-fluorouracil-based chemotherapy. Oncogene 2007, 26:4383-4393.
14. Namikawa H., Fukushima M., Murakami K., Suzuki A., Takasawa S., Okamoto H., et al. Expression of Reg/PAP family members during motor nerve regeneration in rat. Biochem Biophys Res Commun 2005, 24:126-134.
15. Nanakin A., Fukui H., Fujii S., Sekikawa A., Kanda N., Hisatsune H., et al. Expression of the Reg IV gene in ulcerative colitis. Lab Invest 2007, 87:304-314.
16. Okamoto H. The reg gene family and reg proteins: with special attention to the regeneration of pancreatic β-cells. J Hepatobiliary Pancreat Surg 1999, 6:254-262.
17. Okamoto H., Takasawa S. Recent advances in the Okamoto model. The CD38-cyclic ADP-ribose signal system and the regenerating gene protein (reg)-reg receptor system in β-cells. Diabetes 2002, 51:462-473.
18. Orenes-Piñero E., Corton M., Gonzales-Peramato P., Algaba F., Casal I., Serrano A., et al. Searching urinary tumor markers for bladder cancer using a two-dimensional differential gel electrophoresis (2D-DIGE) approach. J Proteome Res 2007, 6:4440-4448.
19. Oue N., Mitani Y., Aung P.P., Sakakura C., Takeshima Y., Kaneko M., et al. Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma. J Pathol 2005, 207:185-198.
20. Ozturk M., de la Monte S.M., Gross J., Wands J.R. Elevated levels of an exocrine pancreatic secretory protein in Alzheimer disease brain. Proc Natl Acad Sci USA 1989, 86:419-423.
21. Roufosse C., Cook H.T. Stem cells and renal regeneration. Nephron Exp Nephrol 2008, 109:39-45.
22. Staack A., Hayward S.W., Baskin L.S., Cunha G.R. Molecular, cellular and developmental biology of urothelium as a basis of bladder regeneration. Differentiation 2005, 73:121-133.
23. Starcevic-Klasan G., Azman J., Picard A., Jurisic-Erzen D., Nikolic M., Jerkovic R. Reg IV protein is expressed in normal rat tissue. Coll Antropol 2008, 32:89-93.
24. Sutherland R.S., Baskin L.S., Hayward S.W., Cunha G.R. Regeneration of bladder urothelium, smooth muscle, blood vessels and nerves into an acellular tissue matrix. J Urol 1996, 156:571-577.
25. Takehara A., Eguchi H., Ohigashi H., Ishikawa O., Kasugai T., Hosokawa M., et al. Novel tumor marker REG 4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4. Cancer Sci 2006, 11:1191-1197.
26. Terazono K., Yamamoto H., Takasawa S., Shiga K., Yonemura Y., Tochino Y., et al. A novel gene activated in regenerating islets. J Biol Chem 1988, 263:2111-2114.
27. Violette S., Festor E., Pandrea-Vasile I., Mitchell V., Adida C., Dussaulx E., et al. Reg IV, a new member of the regenerating gene family, is overexpressed in colorectal carcinomas. Int J Cancer 2003, 103:185-193.
28. Watanabe T., Yonekura H., Terazono K., Yamamoto H., Okamoto H. Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues. The reg protein, pancreatic stone protein, and pancreatic thread protein is one and the same product of the gene. J Biol Chem 1993, 268:7432-7439.
29. Yonemura Y., Takashima T., Miwa K., Miyazaki I., Yamamoto H., Okamoto H. Amelioration of diabetes mellitus in partially depancreatized rats by poly(ADP-ribose) synthetase inhibitors. Evidence of islets B-cell regeneration. Diabetes 1984, 33:401-404.
30. Zhang Y., Lai M., Lv B., Gu X., Wang H., Zhu Y., et al. Overexpression of Reg IV in colorectal adenoma. Cancer Lett 2003, 200:69-76.