Study of GT-repeat expansion in Heme oxygenase-1 gene promoter as genetic cause of male infertility

Journal of Assisted Reproduction and Genetics

Volumn 28, Issue 8, 2011, Pages 737-741

  Siasi, Elham ^a   Aleyasin, Ahmad ^b   Mowla, Seyed Javad ^a   Sahebkashaf, Hamid ^c  

^a TARBIAT MODARES UNIVERSITY   (Iran)

^b NATIONAL INSTITUTE OF GENETIC ENGINEERING AND BIOTECHNOLOGY   (Iran)

^c Navide Institute of Infertility   (Iran)

Author keywords

Heme oxygenase 1 gene; Male infertility; Oxidative stress; Polymorphism

Indexed keywords

HEME OXYGENASE 1;

ALLELE; ARTICLE; AZOOSPERMIA; CONTROL GROUP; GENE FREQUENCY; GENOTYPE; HUMAN; IRAN; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; OLIGOSPERMIA; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS;

ALLELES; AZOOSPERMIA; CASE-CONTROL STUDIES; DINUCLEOTIDE REPEATS; GENOTYPE; HEME OXYGENASE-1; HUMANS; IRAN; MALE; OLIGOSPERMIA; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; SEMEN;

EID: 80755190121     PISSN: 10580468     EISSN: 15737330     Source Type: Journal    
DOI: 10.1007/s10815-011-9574-0     Document Type: Article

References (27)

1. Rao AV, Rao GL. Carotenoids and human health. Pharmacol Res. 2007; 55: 207-16. (Pubitemid 46518154)
2. Iwasaki A, Gagnon C. Formation of reactive oxygen species in spermatozoa of infertile patients. Fertile Steril. 1992; 57: 409-16.
3. Zini A, de Lamirande E, Gagnon C. Reactive oxygen species in semen of infertile patients: levels of superoxide dismutase and catalase-like activities in seminal plasma and spermatozoa. Int J Androl. 1993; 16: 183-8. (Pubitemid 23241013)
4. Lewin A, Lavon H. The effect of coenzyme Q10 on sperm motility and function. Mol Aspects Med. 1997; 18(suppl): 213-9.
5. Moncada ML, Vicari E, Cimino C, Calogero AE, Mongioi A, D'Agata R. Effect of actylcamitine in oligoasthenospermia patients. Acta Eur Fertil. 2002; 23: 221-4.
6. McCoubrey KJ, Maines M. The structure, organization, and differential expression of the gene encoding rat heme oxygenase 2. Gene. 1994; 139: 155-61. (Pubitemid 24078716)
7. Agarwal A, Nick HS. Renal responses to tissue injury: lessons from heme oxygenase-1. Ablation and expression. J Am Soc Nephrol. 2000; 11: 965-73. (Pubitemid 30241733)
8. Lavrovsky Y, Schwartzman MC, Levere RD, Kappas A, Abraham NG. Identification of binding sites for transcription factors NF-kB and AP-2 in the promoter region of the human heme oxygenase-1 gene. Proc Natl Acad Sci USA. 1994; 91: 5987-91. (Pubitemid 24188267)
9. Deshane J, Wright M, Agarwal A. Heme oxygenase-1 expression in disease states. Acta Biochim Pol. 2005; 52: 273-84. (Pubitemid 41133762)
10. Yamada N, Yamada M, Okinaga S. Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. Am J Hum Genet. 2000; 66: 187-95. (Pubitemid 30481482)
11. Chen YH, Chau LY, Lin MW, Chen LC, Yo MH, Chen JW, et al. Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with angiographic restenosis after coronary stenting. Eur Heart J. 2004; 25: 39-47.
12. Chen YH, Chen JW, Chau LY, Lin SJ. Serum bilirubin and ferritin levels link heme oxygenase-1 gene promoter polymorphism and susceptibility to coronary artery disease in diabetic patients. Diabetes Care. 2008; 31(8): 1615-20.
13. Vashist YK, Blessmann M, Trump F, Kalinin V, Kutup A, Schneider C, et al. Microsatellite GTn-repeat polymorphism in the promoter of heme oxygenase-1 gene is an independent predictor of tumor recurrence in male oral squamous cell carcinoma patients. J Oral Pathol Med. 2008; 37: 480-4.
14. Wu MM, Chiou HY, Lee TC, Chen CL, Hsu L, Wang YH, et al. GT- repeat polymorphism in the heme oxygenase-1 gene promoter and the risk of carotid atherosclerosis related to arsenic exposure. J Biomed Sci. 2010; 17(70): 1-11.
15. Aitken RJ. Molecular mechanisms regulating human sperm function. Mol Hum Reprod. 1997; 3: 169-73.
16. Aitken RJ. The human spermatozoon a cell in crisis? J Reprod Fertile. 1999; 115: 1-7.
17. Saleh RA, Agarwal A, Nada EA, El-Tonsy MH, Sharma RK, Meyer A, et al. Negative effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility. Fertile Steril. 2003; 79: 1597-605. (Pubitemid 36687939)
18. Agarwal A, Prabakaran SA. Oxidative stress and antioxidants inmale infertility: a difficult balance. Iran J Reprod Med. 2005; 3(1): 1-8.
19. Agarwal A, Makker K, Sharma R. Clinical relevance of oxidative stress in male factor infertility: an update. Am J Reprod Immunol. 2008; 59: 2-11. (Pubitemid 350285578)
20. Verit FF, Verit A, Ciftci H, Erel O, Celik H. Paraoxonase-1 activity in subfertile men and relationship to sperm parameters. J Androl. 2009; 30(2): 183-9.
21. Abdel Aziz MT, Mostafa T, Roshdy N, Hosni H, Rashed L, Sabry D, et al. Heme oxygenase enzyme activity in human seminal plasma of fertile and infertile males. Andrologia. 2008; 40: 292-7.
22. Pasqualotto FF, Sharma RK, Nelson DR, Thomas AJ, Agarwal A. Relationship between oxidative stress, semen characteristics, and clinical diagnosis in men undergoing infertility investigation. Fertile Steril. 2000; 73(3): 459-64. (Pubitemid 30109638)
23. Sambrook J, Fritsch E, Maniatis T. Isolation of DNA from mammalian cells. Molecular Cloning Cold Spring Harbour Press, Cold Spring Harbour Laboratory, New York, USA 1989, Vol 7, Chap 6.
24. Shibahara S, Sato M, Muller RM, Yoshida T. Structural organization of the human heme oxygenase gene and the function of its promoter. Eur J Biochem. 1989; 179: 557-63. (Pubitemid 19062330)
25. Chen YH, Lin SJ, Lin MW, Tsai HL, Kuo SS, Chen JW, et al. Microsatellite polymorphism in promoter of heme oxygenase-1 gene associated with susceptibility to coronary artery disease in type 2 diabetic patients. Hum Genet. 2002; 111: 1-8.
26. Kaneda H, Ohno M, Taguchi J, Togo M, Hashimoto H, Ogasawara K, et al. Heme oxygenase-1 gene promoter polymorphism is associated with coronary artery disease in Japanese patients with coronary risk factors. Arterioscler Thromb Vasc Biol. 2002; 22: 1680-5.
27. Lin Q, Weis S, Yang G, Weng YH, Helston R, Rish K, et al. Heme oxygenase-1 protein localises to the nucleus and activates transcription factors important in oxidative stress. J Biol Chem. 2007; 282: 20621-33. (Pubitemid 47100046)