Evaluation of cholinesterase inhibitory and antioxidant activities of wild and cultivated samples of sage (Salvia fruticosa) by activity-guided fractionation

Journal of Medicinal Food

Volumn 14, Issue 11, 2011, Pages 1476-1483

  Şenol, Fatma Sezer ^a   Orhan, Ilkay Erdogan ^a   Erdem, Sinem Aslan ^b   Kartal, Murat ^b   Şener, Bilge ^a   Kan, Yüksel ^c   Celep, Ferhat ^d   Kahraman, Ahmet ^d   Dogan, Musa ^d  

^a GAZI UNIVERSITY   (Turkey)

^b ANKARA UNIVERSITY   (Turkey)

^c SELCUK UNIVERSITY   (Turkey)

^d MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

Author keywords

antioxidant activity; cholinesterase inhibition; chromatography; essential oil; Salvia fruticosa

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ACETIC ACID ETHYL ESTER; ALCOHOL; ANTIOXIDANT; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; DICHLOROMETHANE; PLANT EXTRACT; SALVIA FRUTICOSA EXTRACT; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLINESTERASE INHIBITION; COLUMN CHROMATOGRAPHY; COMPARATIVE STUDY; CULTIVATED SPECIES; EVALUATION; FRACTIONATION; GAS CHROMATOGRAPHY; IRON CHELATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SALVIA; SALVIA FRUTICOSA; SAMPLE; SPECTROPHOTOMETRY; WILD PLANT;

ACETYLCHOLINESTERASE; ANTIOXIDANTS; BIPHENYL COMPOUNDS; BUTYRYLCHOLINESTERASE; CHEMICAL FRACTIONATION; CHOLINESTERASE INHIBITORS; CHOLINESTERASES; FREE RADICAL SCAVENGERS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; OILS, VOLATILE; PICRATES; PLANT EXTRACTS; SALVIA OFFICINALIS;

SALVIA; SALVIA FRUTICOSA;

EID: 80755182259     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2010.0158     Document Type: Article

References (24)

1. Scarpini E, Scheltens P, Feldman H: Treatment of Alzheimer's disease: current status and new perspectives. Lancet 2003;2:539-547. (Pubitemid 36994993)
2. Fillit H, Hill J: Economics of dementia and pharmacoeconomics of dementia therapy. Am J Geriat Pharmacother 2005;3:39-49. (Pubitemid 41122357)
3. Grossberg G: Cholinesterase inhibitors for the treatment of Alzheimer's disease: getting on and staying on. Curr Therap Res 2003;64:216-235. (Pubitemid 36692841)
4. Perry N, Court G, Bidet N, Court J, Perry EK: Cholinergic activities of European herbs and potential for dementia therapy. J Ger Psych 1996;11:1063-1069. (Pubitemid 27029813)
5. Celep F, Dogan M, Duran A: A new record for the Flora of Turkey: Salvia viscosa Jacq. (Labiatae). Turk J Bot 2009;33:57-60
6. Baytop T: Therapy with Medicinal Plants in Turkey (Past and Present). Istanbul University Publications No 3255. Istanbul, Turkey, Nobel Press House, 1999.
7. Orhan I, Kartal M, Naz Q, et al.: Antioxidant and anticholinesterase evaluation of selected Turkish Salvia species. Food Chem 2007;103:1247-1254. (Pubitemid 46467116)
8. Sxenol FS, Orhan I, Celep F, et al.: Survey of 55 Turkish Salvia taxa for their acetylcholinesterase and antioxidant activities. Food Chem 2010;120:34-43.
9. Mandel S, Amit T, Bar-Am O, Youdim MBH: Iron dysregulation in Alzheimer's disease: Multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents. Prog Neurobiol 2007;82:348-360. (Pubitemid 47126678)
10. Ellman GL, Courtney KD, Andres V, Featherstone RM: A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961;7:88-95.
11. Blois MS: Antioxidant determinations by the use of a stable free radical. Nature 1958;181:1199-1200.
12. Chua MT, Tung YT, Chang ST: Antioxidant activities of ethanolic extracts from the twigs of Cinnamomum osmophleum. Biores Technol 2008;99:1918-1925.
13. Oyaizu M: Studies on products of browning reactions-antioxidative activities of products of browning reaction prepared from glucosamine. Jap J Nutr 1986;44:307-315.
14. Perry N, Houghton PJ, Theobold A, Jenner P, Perry EK: In vitro inhibition of human erythrocyte acetylcholinesterase by Salvia lavandulaefolia essential oil and constituent terpenes. J Pharm Pharmacol 2000;52:895-902. (Pubitemid 30461925)
15. Savelev SU, Okello EJ, Perry EK: Butyryl- and acetyl-cholinesterase inhibitory activities in essential oils of Salvia species and their constituents. Phytother Res 2004;18:315-324. (Pubitemid 38619534)
16. Orhan I, Aslan M: Appraisal of scopolamine-induced antiamnesic effect in mice and in vitro antiacetylcholinesterase and antioxidant activities of some traditionally used Lamiaceae plants. J Ethnopharmacol 2009;122:327-332.
17. Ren Y, Houghton PJ, Hider RC, Howes MR: Novel diterpenoid acetylcholinesterase inhibitors. Planta Med 2004;70:201-204.
18. Lin HQ, Ho MT, Lau LS, et al.: Anti-acetylcholinesterase activities of traditional Chinese medicine for treating Alzheimer's disease. Chemico-Biol Int 2008;175:352-354.
19. Kim DH, Jeon SJ, Jung JW, et al.: Tanshinone congeners improve memory impairments induced by scopolamine on passive avoidance tasks in mice. Eur J Pharmacol 2007;574:140-147. (Pubitemid 47592846)
20. Mehmood S, Riaz N, Nawaz SA, et al.: New butyrylcholinesterase inhibitory triterpenes from Salvia santolinifolia. Arch Pharm Res 2006;29:195-198. (Pubitemid 43699529)
21. Salah SM, Jager AK: Screening of traditionally used Lebanese herbs for neurological activities. J Ethnopharmacol 2005;97:145-149. (Pubitemid 40094540)
22. Triantaphyllou K, Blekas G, Boskou D: Antioxidative properties of water extracts obtained from herbs of the species Lamiaceae. Int J Food Sci Nutr 2001;52:313-317. (Pubitemid 32677278)
23. Pizzale L, Bortolomeazzi R, Vichi S, et al.: Antioxidant activity of sage (Salvia officinalis and S. fruticosa) and oregano (Origanum onites and O. intercedens) extracts related to their phenolic compound content. J Sci Food Agric 2002;82:1645-1651.
24. Ü rek Ö ztürk R, Kayali Ayar H, Nakiboglu M, Tarhan L: Comparison of antioxidant capacities of the leaves and flowers of Salvia fruticosa grown in Turkey. Asian J Chem 2008;20:2091-2098.