On-chip modulation of evanescent illumination and live-cell imaging with polymer waveguides

Optics Express

Volumn 19, Issue 23, 2011, Pages 22929-22935

  Agnarsson, Björn ^a,b   Jonsdottir, Asta B ^a,c   Arnfinnsdottir, Nina B ^a,d   Leosson, Kristjan ^a  

^a UNIVERSITY OF ICELAND   (Iceland)

^b CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^c HUTCHISON MRC RESEARCH CENTRE   (United Kingdom)

^d NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENCE MICROSCOPY; LIGHT MODULATORS; PHOTOBLEACHING;

EVANESCENT ILLUMINATION; EXCITATION LIGHT; HIGH-RESOLUTION IMAGING; LIVE CELL; LIVE-CELL IMAGING; NEAR-SURFACE; ON CHIPS; PHOTO-TOXICITY; POLYMER WAVEGUIDES;

WAVEGUIDE COMPONENTS;

POLYMER;

ANIMAL; ARTICLE; CELL STRAIN; CELL SURVIVAL; CHEMISTRY; FOCAL ADHESION; INTERFEROMETRY; LAB ON A CHIP; LIGHT; METABOLISM; METHODOLOGY; MICROSCOPY; SWINE; THREE DIMENSIONAL IMAGING;

ANIMALS; CELL SURVIVAL; FOCAL ADHESIONS; IMAGING, THREE-DIMENSIONAL; INTERFEROMETRY; LAB-ON-A-CHIP DEVICES; LIGHT; LLC-PK1 CELLS; MICROSCOPY; POLYMERS; SWINE;

EID: 80755180976     PISSN: None     EISSN: 10944087     Source Type: Journal    
DOI: 10.1364/OE.19.022929     Document Type: Article

References (29)

1. M. M. Frigault, J. Lacoste, J. L. Swift, and C. M. Brown, "Live-cell microscopy -tips and tools," J. Cell Sci. 122(6), 753-767 (2009).
2. D. J. Stephens and V. J. Allan, "Light microscopy techniques for live cell imaging," Science 300(5616), 82-86 (2003).
3. J. R. Lakowicz, Principles of Fluorescence Spectroscopy (Springer, 2006).
4. D. I. Pattison and M. J. Davies, "Actions of ultraviolet light on cellular structures," EXS 96, 131-157 (2006).
5. R. A. Hoebe, H. T. Van der Voort, J. Stap, C. J. Van Noorden, and E. M. Manders, "Quantitative determination of the reduction of phototoxicity and photobleaching by controlled light exposure microscopy," J. Microsc. 231(1), 9-20 (2008).
6. D. M. Benson, J. Bryan, A. L. Plant, A. M. Gotto, Jr., and L. C. Smith, "Digital imaging fluorescence microscopy: Spatial heterogeneity of photobleaching rate constants in individual cells," J. Cell Biol. 100(4), 1309-1323 (1985).
7. H. Schneckenburger, "Total internal reflection fluorescence microscopy: Technical innovations and novel applications," Curr. Opin. Biotechnol. 16(1), 13-18 (2005).
8. D. Axelrod, "Total internal reflection fluorescence microscopy in cell biology," Traffic 2(11), 764-774 (2001).
9. C. Joselevitch and D. Zenisek, "Imaging Exocytosis in Retinal Bipolar Cells with TIRF Microscopy," (2009) http://www.jove.com/video/1305/ imaging-exocytosis-in-retinal-bipolar-cells-with-tirf-microscopy.
10. A. Hassanzadeh and S. Mittler, "Waveguide evanescent field fluorescence microscopy: High contrast imaging of a domain forming mixed lipid Langmuir-Blodgett monolayer mimicking lung surfactant," J. Biomed. Opt. 16(4), 046022 (2011).
11. H. M. Grandin, B. Städler, M. Textor, and J. Vörös, "Waveguide excitation fluorescence microscopy: A new tool for sensing and imaging the biointerface," Biosens. Bioelectron. 21(8), 1476-1482 (2006).
12. R. Horvath, H. C. Pedersen, N. Skivesen, C. Svanberg, and N. B. Larsen, "Fabrication of reverse symmetry polymer waveguide sensor chips on nanoporous substrates using dip-floating," J. Micromech. Microeng. 15(6), 1260-1264 (2005).
13. R. Horváth, R. L. Lindvold, and N. B. Larsen, "Reverse symmetry waveguides: Theory and fabrication," Appl. Phys. B 74(4-5), 383-393 (2002).
14. R. Horvath, K. Cottier, H. C. Pedersen, and J. J. Ramsden, "Multidepth screening of living cells using optical waveguides," Biosens. Bioelectron. 24(4), 799-810 (2008).
15. J. J. Ramsden and R. Horvath, "Optical biosensors for cell adhesion," J. Recept. Signal Transduct. Res. 29(3-4), 211-223 (2009).
16. B. Agnarsson, S. Ingthorsson, T. Gudjonsson, and K. Leosson, "Evanescent-wave fluorescence microscopy using symmetric planar waveguides," Opt. Express 17(7), 5075-5082 (2009).
17. B. Agnarsson, J. Halldorsson, N. Arnfinnsdottir, S. Ingthorsson, T. Gudjonsson, and K. Leosson, "Fabrication of planar polymer waveguides for evanescent-wave sensing in aqueous environments," Microelectron. Eng. 87(1), 56-61 (2010).
18. J. Halldorsson, N. B. Arnfinnsdottir, A. B. Jonsdottir, B. Agnarsson, and K. Leosson, "High index contrast polymer waveguide platform for integrated biophotonics," Opt. Express 18(15), 16217-16226 (2010).
19. Z. Zhang, P. Zhao, P. Lin, and F. Sun, "Thermo-optic coefficients of polymers for optical waveguide applications," Polymer (Guildf.) 47(14), 4893-4896 (2006).
20. F. Prieto, B. Sepulveda, A. Calle, A. Llobera, C. Dominguez, A. Abad, A. Montoya, and L. Lechuga, "An integrated optical interferometric nanodevice based on silicon technology for biosensor applications," Nanotechnology 14(8), 907-912 (2003).
21. W. Lukosz, "Integrated optical chemical and direct biochemical sensors," Sensor. Actuat Biol. Chem. 29, 37-50 (1995).
22. A. Densmore, S. Janz, R. Ma, J. H. Schmid, D. X. Xu, A. Delâge, J. Lapointe, M. Vachon, and P. Cheben, "Compact and low power thermo-optic switch using folded silicon waveguides," Opt. Express 17(13), 10457-10465 (2009).
23. B. Maisenholder, H. Zappe, R. Kunz, P. Riel, M. Moser, and J. Edlinger, "A GaAs/AlGaAs-based refracto-meter platform for integrated optical sensing applications," Sensor. Actuat, Biol. Chem. 39, 324-329 (1997).
24. C. Vieu, F. Carcenac, A. Pepin, and Y. Chen, "Electron beam lithography: Resolution limits and applications," Appl. Surf. Sci. 164(1-4), 111-117 (2000).
25. G. Coppola, L. Sirleto, I. Rendina, and M. Iodice, "Advance in thermo-optical switches: Principles, materials, design, and device structure," Opt. Eng. 50(7), 071112 (2011).
26. T. Rosenzveig, P. Hermannsson, A. Boltasseva, and K. Leosson, "Optimizing performance of plasmonic devices for photonic circuits," Appl. Phys., A Mater. Sci. Process. 100(2), 341-346 (2010).
27. J. Kirchner, Z. Kam, G. Tzur, A. D. Bershadsky, and B. Geiger, "Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption," J. Cell Sci. 116(6), 975-986 (2003).
28. E. Zamir and B. Geiger, "Molecular complexity and dynamics of cell-matrix adhesions," J. Cell Sci. 114(Pt 20), 3583-3590 (2001).
29. G. Carpenter and S. Cohen, "Epidermal growth factor," J. Biol. Chem. 265(14), 7709-7712 (1990).