Anion effects on sodium ion and acid molecule adduction to protein ions in electrospray ionization mass spectrometry

Journal of the American Society for Mass Spectrometry

Volumn 22, Issue 11, 2011, Pages 1968-1977

  Flick, Tawnya G ^a   Merenbloom, Samuel I ^a   Williams, Evan R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adduction; Anion; Electrospray; Hofmeister series; Proteins; Sodium

Indexed keywords

ACID MOLECULES; ADDUCTION; ANION; ANION EFFECTS; CHARGED PROTEINS; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; ELECTROSPRAYS; HOFMEISTER SERIES; ION INTERACTIONS; MILLIMOLAR CONCENTRATIONS; PROTEIN IONS; PROTEIN STRUCTURES; PROTON AFFINITY; SODIUM IONS; SODIUM SALT;

COMPLEXATION; ELECTROSPRAY IONIZATION; IONIZATION; MASS SPECTROMETRY; METAL IONS; MOLECULES; NEGATIVE IONS; SALTS;

PROTEINS;

ALPHA LACTALBUMIN; ANION; BETA LACTOGLOBULIN; CALMODULIN; MYOGLOBIN; PROTEIN; SODIUM ION;

ADDUCTION; ARTICLE; ELECTROSPRAY MASS SPECTROMETRY; ENTHALPY; ISOELECTRIC POINT; PROTEIN DENATURATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTON TRANSPORT; SOLUBILITY; TEMPERATURE DEPENDENCE; UBIQUITINATION; VISCOSITY;

ACIDS; ANIMALS; ANIONS; PROTEINS; PROTONS; SODIUM; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 80755171167     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-011-0218-5     Document Type: Article

References (49)

1. R MacKinnon 2004 Potassium Channels and the Atomic Basis of Selective Ion Conduction (Nobel Lecture) Angew. Chem. Int. Edit. 43 4265 4277 10.1002/anie.200400662 1:CAS:528:DC%2BD2cXnsVOmur0%3D (Pubitemid 39257401)
2. WA Catterall 1995 Structure and Function of Voltage-Gated Ion Channels Annu. Rev. Biochem. 64 493 531 10.1146/annurev.bi.64.070195.002425 1:CAS:528:DyaK2MXmsl2qsbc%3D
3. M Hiraoka S Kawano Y Hirano T Furukawa 1998 Role of Cardiac Chloride Currents in Changes in Action Potential Characteristics and Arrhythmias Cardiovasc. Res. 40 23 33 10.1016/S0008-6363(98)00173-4 1:CAS:528: DyaK1cXmt12ns7k%3D (Pubitemid 28435426)
4. A Crivici M Ikura 1995 Molecular and Structural Basis of Target Recognition by Calmodulin Annu. Rev. Biophys. Biomol. Struct. 24 85 116 10.1146/annurev.bb.24.060195.000505 1:CAS:528:DyaK2MXmt1ams7g%3D
5. 2+, Ionic-Strength, and pH J. Biochem. 97 1011 1023 1:CAS:528:DyaL2MXhvF2rt78%3D (Pubitemid 15097910)
6. GS Jackson I Murray LLP Hosszu N Gibbs JP Waltho AR Clarke J Collinge 2001 Location and Properties of Metal-Binding Sites on the Human Prion Protein Proc. Natl. Acad. Sci. U.S.A. 98 8531 8535 10.1073/pnas.151038498 1:CAS:528:DC%2BD3MXls1Wisbo%3D (Pubitemid 32678062)
7. S Lehmann 2002 Metal Ions and Prion Diseases Curr. Opin. Chem. Biol. 6 187 192 10.1016/S1367-5931(02)00295-8 1:CAS:528:DC%2BD38XitlGnsrw%3D (Pubitemid 34251374)
8. BS Wong SG Chen M Colucci ZL Xie T Pan T Liu RL Li P Gambetti MS Sy DR Brown 2001 Aberrant Metal Binding by Prion Protein in Human Prion Disease J. Neurochem. 78 1400 1408 10.1046/j.1471-4159.2001.00522.x 1:CAS:528: DC%2BD3MXnt12isL4%3D (Pubitemid 32899771)
9. JA Duce AI Bush 2010 Biological Metals and Alzheimer's Disease: Implications for Therapeutics and Diagnostics Prog. Neurobiol. 92 1 18 10.1016/j.pneurobio.2010.04.003 1:CAS:528:DC%2BC3cXpvVKmtbk%3D
10. AI Bush 2003 The Metallobiology of Alzheimer's Disease Trends Neurosci. 26 207 214 10.1016/S0166-2236(03)00067-5 1:CAS:528:DC%2BD3sXis12nsb8%3D (Pubitemid 36412003)
11. F Hofmeister 1888 Arch. Exp. Pathol. Pharmakol. 24 247 260 10.1007/BF01918191
12. W Kunz J Henle BW Ninham 2004 'Zur Lehre Von Der Wirkung Der Salze' (About the Science of the Effect of Salts): Franz Hofmeister's Historical Papers Curr. Opin. Colloid Interface Sci. 9 19 37 10.1016/j.cocis.2004.05.005 1:CAS:528:DC%2BD2cXntlSrtLo%3D (Pubitemid 39194131)
13. J Cheng CD Vecitis MR Hoffmann AJ Colussi 2006 Experimental Anion Affinities for the Air/Water Interface J. Phys. Chem. B 110 25598 25602 10.1021/jp066197k 1:CAS:528:DC%2BD28Xht1Chsb7E (Pubitemid 46133262)
14. YJ Zhang PS Cremer 2009 The Inverse and Direct Hofmeister Series for Lysozyme Proc. Natl. Acad. Sci. U.S.A. 106 15249 15253 10.1073/pnas.0907616106 1:CAS:528:DC%2BD1MXhtFGgtr7N
15. B Hribar NT Southall V Vlachy KA Dill 2002 How Ions Affect the Structure of Water J. Am. Chem. Soc. 124 12302 12311 10.1021/ja026014h 1:CAS:528:DC%2BD38XntFeisLY%3D (Pubitemid 35157776)
16. YH Cho YJ Zhang T Christensen LB Sagle A Chilkoti PS Cremer 2008 Effects of Hofmeister Anions on the Phase Transition Temperature of Elastin-Like Polypeptides J. Phys. Chem. B 112 13765 13771 10.1021/jp8062977 1:CAS:528:DC%2BD1cXht1ahs7fK
17. Y Zhang S Furyk LB Sagle Y Cho DE Bergbreiter PS Cremer 2007 Effects of Hofmeister Anions on the LCST of PNIPAM as a Function of Molecular Weight J. Phys. Chem. C 111 8916 8924 10.1021/jp0690603 1:CAS:528:DC%2BD2sXktVWmtr4%3D (Pubitemid 47152601)
18. MW Washabaugh KD Collins 1986 The Systematic Characterization by Aqueous Column Chromatography of Solutes which Affect Protein Stability J. Biol. Chem. 261 2477 2485
19. M Bostrom FW Tavares S Finet F Skouri-Panet A Tardieu BW Ninham 2005 Why Forces between Proteins Follow Different Hofmeister Series for pH above and Below pI Biophys. Chem. 117 217 224 10.1016/j.bpc.2005.05.010 1:STN:280:DC%2BD2MvotVGrsw%3D%3D (Pubitemid 41253596)
20. S Finet F Skouri-Panet M Casselyn F Bonnete A Tardieu 2004 The Hofmeister Effect as Seen by SAXS in Protein Solutions Curr. Opin. Colloid Interface Sci. 9 112 116 10.1016/j.cocis.2004.05.014 1:CAS:528:DC%2BD2cXntlSrtbc%3D (Pubitemid 39194145)
21. JS Uejio CP Schwartz AM Duffin WS Drisdell RC Cohen RJ Saykally 2008 Characterization of Selective Binding of Alkali Cations with Carboxylate by X-Ray Absorption Spectroscopy of Liquid Microjets Proc. Natl. Acad. Sci. U.S.A. 105 6809 6812 10.1073/pnas.0800181105 1:CAS:528:DC%2BD1cXmt1GisrY%3D (Pubitemid 351754486)
22. JD Smith RJ Saykally PL Geissler 2007 The Effects of Dissolved Halide Anions on Hydrogen Bonding in Liquid Water J. Am. Chem. Soc. 129 13847 13856 10.1021/ja071933z 1:CAS:528:DC%2BD2sXht1WltLjI (Pubitemid 350106074)
23. MG Freire C Neves AMS Silva L Santos IM Marrucho LPN Rebelo JK Shah EJ Maginn JAP Coutinho 2010 H-1 NMR and Molecular Dynamics Evidence for an Unexpected Interaction on the Origin of Salting-In/Salting-Out Phenomena J. Phys. Chem. B 114 2004 2014 10.1021/jp9095634 1:CAS:528:DC%2BC3cXot1Kqtg%3D%3D
24. X Chen T Yang S Kataoka PS Cremer 2007 Specific Ion Effects on Interfacial Water Structure near Macromolecules J. Am. Chem. Soc. 129 12272 12279 10.1021/ja073869r 1:CAS:528:DC%2BD2sXhtVGhtrfL (Pubitemid 47556862)
25. JT O'Brien JS Prell MF Bush ER Williams 2010 Sulfate Ion Patterns Water at Long Distance J. Am. Chem. Soc. 132 8248 8249 10.1021/ja1024113
26. AW Omta MF Kropman S Woutersen HJ Bakker 2003 Negligible Effect of Ions on the Hydrogen-Bond Structure in Liquid Water Science 301 347 349 10.1126/science.1084801 1:CAS:528:DC%2BD3sXls1yhsLo%3D (Pubitemid 36877064)
27. JS Prell JT O'Brien ER Williams 2011 Structural and Electric Field Effects of Ions in Aqueous Nanodrops J. Am. Chem. Soc. 133 4810 4818 10.1021/ja108341t 1:CAS:528:DC%2BC3MXjt1yru7k%3D
28. JX Pan K Xu XD Yang WY Choy L Konermann 2009 Solution-Phase Chelators for Suppressing Nonspecific Protein-Metal Interactions in Electrospray Mass Spectrometry Anal. Chem. 81 5008 5015 10.1021/ac900423x 1:CAS:528: DC%2BD1MXlvVyru78%3D
29. TG Flick SI Merenbloom ER Williams 2011 A Simple and Robust Method for Determining the Number of Basic Sites in Peptides and Proteins Using Electrospray Ionization Mass Spectrometry Anal. Chem. 83 2210 2214 10.1021/ac1031012 1:CAS:528:DC%2BC3MXit1Wjt7g%3D
30. SK Chowdhury V Katta RC Beavis BT Chait 1990 Origin and Removal of Adducts (Molecular Mass=98 U) Attached to Peptide and Protein Ions in Electrospray Ionization Mass-Spectra J. Am. Soc. Mass Spectrom. 1 382 388 10.1016/1044-0305(90)85018-H 1:CAS:528:DyaK3MXmt1KrsQ%3D%3D
31. P Pan HP Gunawardena Y Xia SA McLuckey 2004 Nanoelectrospray Ionization of Protein Mixtures: Solution pH and Protein pI Anal. Chem. 76 1165 1174 10.1021/ac035209k 1:CAS:528:DC%2BD2cXhtFCksLw%3D (Pubitemid 38235567)
32. CL Liu QY Wu AC Harms RD Smith 1996 On Line Microdialysis Sample Cleanup for Electrospray Ionization Mass-Spectrometry of Nucleic Acid Samples Anal. Chem. 68 3295 3299 10.1021/ac960286j 1:CAS:528:DyaK28XkvVektbs%3D (Pubitemid 26320501)
33. P Pan SA McLuckey 2003 The Effect of Small Cations on the Positive Electrospray Responses of Proteins at Low pH Anal. Chem. 75 5468 5474 10.1021/ac034344u 1:CAS:528:DC%2BD3sXmsl2gurk%3D (Pubitemid 37280574)
34. AT Iavarone OA Udekwu ER Williams 2004 Buffer Loading for Counteracting Metal Salt-Induced Signal Suppression in Electrospray Ionization Anal. Chem. 76 3944 3950 10.1021/ac049724+ 1:CAS:528:DC%2BD2cXktlymtbk%3D (Pubitemid 38943663)
35. HJ Sterling JD Batchelor DE Wemmer ER Williams 2010 Effects of Buffer Loading for Electrospray Ionization Mass Spectrometry of a Noncovalent Protein Complex That Requires High Concentrations of Essential Salts J. Am. Soc. Mass Spectrom. 21 1045 1049 10.1016/j.jasms.2010.02.003 1:CAS:528: DC%2BC3cXmt1ensbc%3D
36. KH Bauer TP Knepper A Maes V Schatz M Voihsel 1999 Analysis of Polar Organic Micropollutants in Water with Ion Chromatography Electrospray Mass Spectrometry J. Chromatogr. A 837 117 128 10.1016/S0021-9673(99)00048-5 1:CAS:528:DyaK1MXitlKjsLs%3D (Pubitemid 29219352)
37. JJ Dalluge 2000 Mass Spectrometry for Direct Determination of Proteins in Cells: Applications in Biotechnology and Microbiology Fresenius J. Anal. Chem. 366 701 711 10.1007/s002160051564 1:CAS:528:DC%2BD3cXhvF2ls7o%3D
38. SD Friess JM Daniel R Hartmann R Zenobi 2002 Mass Spectrometric Noncovalent Probing of Amino Acids in Peptides and Proteins Int. J. Mass Spectrom. 219 269 281 10.1016/S1387-3806(01)00581-4 1:CAS:528: DC%2BD38XmtVWks7k%3D
39. SD Friess R Zenobi 2001 Protein Structure Information from Mass Spectrometry? Selective Titration of Arginine Residues by Sulfonates J. Am. Soc. Mass Spectrom. 12 810 818 10.1016/S1044-0305(01)00257-4 1:CAS:528: DC%2BD3MXksFKksLw%3D (Pubitemid 34546568)
40. B Salih R Zenobi 1998 Maldi Mass Spectrometry of Dye-Peptide and Dye-Protein Complexes Anal. Chem. 70 1536 1543 10.1021/ac9708506 1:CAS:528:DyaK1cXhs1Grt7Y%3D
41. GD Wang RB Cole 1994 Effect of Solution Ionic-Strength on Analyte Charge-State Distributions in Positive and Negative-Ion Electrospray Mass-Spectrometry Anal. Chem. 66 3702 3708 10.1021/ac00093a026 1:CAS:528:DyaK2cXmtVSju70%3D
42. KB Turner SA Monti D Fabris 2008 Like Polarity Ion/Ion Reactions Enable the Investigation of Specific Metal Interactions in Nucleic Acids and Their Noncovalent Assemblies J. Am. Chem. Soc. 130 13353 13363 10.1021/ja8045734 1:CAS:528:DC%2BD1cXhtFaqtLbF
43. YJ Jiang RB Cole 2005 Oligosaccharide Analysis Using Anion Attachment in Negative Mode Electrospray Mass Spectrometry J. Am. Soc. Mass Spectrom. 16 60 70 10.1016/j.jasms.2004.09.006 1:CAS:528:DC%2BD2MXksVGhug%3D%3D (Pubitemid 40093801)
44. Y Cai RB Cole 2002 Stabilization of Anionic Adducts in Negative Ion Electrospray Mass Spectrometry Anal. Chem. 74 985 991 10.1021/ac0108818 1:CAS:528:DC%2BD38Xns1Gquw%3D%3D (Pubitemid 34203020)
45. JL Stephenson SA McLuckey 1997 Gaseous Protein Cations are Amphoteric J. Am. Chem. Soc. 119 1688 1696 10.1021/ja9632973 1:CAS:528:DyaK2sXhvFGnsrg%3D (Pubitemid 27145514)
46. JL Stephenson SA McLuckey 1997 Counting Basic Sites in Oligopeptides Via Gas-Phase Ion Chemistry Anal. Chem. 69 281 285 10.1021/ac961119m 1:CAS:528:DyaK2sXptVagsg%3D%3D (Pubitemid 27101308)
47. JCY Leblanc D Beuchemin KWM Siu R Guevremont SS Berman 1991 Thermal-Denaturation of Some Proteins and Its Effect on Their Electrospray Mass-Spectra Org. Mass Spectrom. 26 831 839 10.1002/oms.1210261005 1:CAS:528:DyaK3MXmsFSmu74%3D
48. CL Gatlin F Tureček 1994 Acidity Determination in Droplets Formed by Electrospraying Methanol-Water Solutions Anal. Chem. 66 712 718 10.1021/ac00077a021 1:CAS:528:DyaK2cXhslCrtr8%3D
49. J Simons HA Kosters RW Visschers HHJ de Jongh 2002 Role of Calcium as Trigger in Thermal β-Lactoglobulin Aggregation Arch. Biochem. Biophys. 406 143 152 10.1016/S0003-9861(02)00429-0 1:CAS:528:DC%2BD38XntlamtL8%3D (Pubitemid 35216340)