Redifferentiation of dedifferentiated chondrocytes by adenoviral vector-mediated TGF-β3 and collagen-1 silencing shRNA in 3D culture

Annals of Biomedical Engineering

Volumn 39, Issue 12, 2011, Pages 3042-3054

  Zhang, Feng ^a   Yao, Yongchang ^a,b   Su, Kai ^a   Pang, Patricia Xiaotian ^a   Zhou, Ruijie ^a   Wang, Yingjun ^b   Wang, Dong An ^a,b  

^a Nanyang Technological University   (Singapore)

^b SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Alginate; Chondrocyte; Dedifferentiation; Redifferentiation; shRNA; TGF 3

Indexed keywords

3D CULTURE; CELL EXPANSION; CHONDROCYTES; CHONDROCYTIC; CHONDROGENESIS; COLLAGEN TYPE I; CONTROL GROUPS; DEDIFFERENTIATION; DOWN-REGULATION; GENE DELIVERY; GENETIC MODIFICATIONS; HIGH EFFICACY; MATRIX PROTEINS; REAL TIME RT-PCR; RECOMBINANT ADENOVIRUS; REDIFFERENTIATION; REGENERATIVE MEDICINE; SHORT HAIRPIN RNA (SHRNA); SHRNA; TRANSFORMING GROWTH FACTORS; TYPE II COLLAGENS;

CARTILAGE; CELL CULTURE; COLLAGEN; ENZYME INHIBITION; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; MONOLAYERS; OLIGOMERS; PLANTS (BOTANY); POLYMERASE CHAIN REACTION; RESTORATION; RNA;

BODY FLUIDS;

AGGRECAN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; TRANSFORMING GROWTH FACTOR BETA3;

ADENOVIRUS; ANIMAL; ARTICLE; BIOSYNTHESIS; CARTILAGE CELL; CELL CULTURE; CELL DEDIFFERENTIATION; CELL DIFFERENTIATION; CYTOLOGY; GENE SILENCING; GENE VECTOR; GENETICS; HUMAN; SWINE;

ADENOVIRIDAE; AGGRECANS; ANIMALS; CELL DEDIFFERENTIATION; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE I; COLLAGEN TYPE II; GENE SILENCING; GENETIC VECTORS; HUMANS; SWINE; TRANSFORMING GROWTH FACTOR BETA3;

EID: 80755147134     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-011-0398-y     Document Type: Article

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