Effects of combinational adenoviral vector-mediated TGFβ3 transgene and shRNA silencing type I collagen on articular chondrogenesis of synovium-derived mesenchymal stem cells

Biotechnology and Bioengineering

Volumn 106, Issue 5, 2010, Pages 818-828

  Yao, Yongchang ^a   Zhang, Feng ^a   Zhou, Ruijie ^a   Su, Kai ^a   Fan, Jiabing ^a   Wang, Dong An ^a  

^a Nanyang Technological University   (Singapore)

Author keywords

Cartilage; Collagen; Hydrogel; shRNA; Synovium derived mesenchymal stem cells; TGF 3

Indexed keywords

CARTILAGE; CELL CULTURE; COLLAGEN; ENCODING (SYMBOLS); ENZYME INHIBITION; HYDROGELS; LIGAMENTS; PLANTS (BOTANY);

ADENOVIRAL VECTORS; ALGINATE HYDROGELS; CHONDROCYTES; CHONDROGENESIS; CHONDROGENIC; CHONDROGENIC DIFFERENTIATION; EXTRACELLULAR MATRIX COMPONENTS; FIBROCARTILAGE; IMMUNOHISTOCHEMICAL STAINING; MARKER GENES; MATRIX PROTEINS; MESENCHYMAL STEM CELL; Q-RT-PCR; REAL TIME RT-PCR; RECOMBINANT ADENOVIRUS; SYNOVIUM; SYNOVIUM-DERIVED MESENCHYMAL STEM CELLS; TRANSFORMING GROWTH FACTORS; TRANSGENE; TRANSGENICS; TYPE I COLLAGEN; TYPE II COLLAGENS; UP-REGULATION;

STEM CELLS;

ADENOVIRUS VECTOR; AGGRECAN; CARTILAGE OLIGOMERIC MATRIX PROTEIN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA3;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CHONDROGENESIS; EXTRACELLULAR MATRIX; GENE SILENCING; HISTOLOGY; IMMUNOHISTOCHEMISTRY; MARKER GENE; MESENCHYMAL STEM CELL; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; SYNOVIUM; TRANSGENE; UPREGULATION; ADENOVIRIDAE; ANTAGONISTS AND INHIBITORS; CYTOCHEMISTRY; CYTOLOGY; GENE EXPRESSION PROFILING; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENOVIRIDAE; CELL DIFFERENTIATION; CHONDROGENESIS; COLLAGEN TYPE I; GENE EXPRESSION PROFILING; GENE SILENCING; GENETIC VECTORS; HISTOCYTOCHEMISTRY; MESENCHYMAL STROMAL CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SYNOVIAL MEMBRANE; TRANSDUCTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA3; TRANSGENES;

EID: 77955368685     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22733     Document Type: Article

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