메뉴 건너뛰기




Volumn 348, Issue 1, 2012, Pages 189-197

A physiological role for androgen actions in the absence of androgen receptor DNA binding activity

Author keywords

Androgen receptor; Bone; ERK 1 2 phosphorylation; Genomic; Knockout; Signaling

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANOLONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; ZINC FINGER PROTEIN;

EID: 80755140656     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2011.08.017     Document Type: Article
Times cited : (25)

References (50)
  • 1
    • 77954492880 scopus 로고    scopus 로고
    • Estradiol induction of spermatogenesis is mediated via an estrogen receptor-α mechanism involving neuroendocrine activation of follicle-stimulating hormone secretion
    • Allan C.M., Couse J.F., Simanainen U., Spaliviero J., Jimenez M., Rodriguez K., Korach K.S., Handelsman D.J. Estradiol induction of spermatogenesis is mediated via an estrogen receptor-α mechanism involving neuroendocrine activation of follicle-stimulating hormone secretion. Endocrinology 2010, 151:2800-2810.
    • (2010) Endocrinology , vol.151 , pp. 2800-2810
    • Allan, C.M.1    Couse, J.F.2    Simanainen, U.3    Spaliviero, J.4    Jimenez, M.5    Rodriguez, K.6    Korach, K.S.7    Handelsman, D.J.8
  • 3
    • 0018263644 scopus 로고
    • Effect of testosterone therapy on bone formation in an osteoporotic hypogonadal male
    • Baran D.T., Bergfeld M.A., Teitelbaum S.L., Avioli L.V. Effect of testosterone therapy on bone formation in an osteoporotic hypogonadal male. Calcif. Tissue Res. 1978, 26:103-106.
    • (1978) Calcif. Tissue Res. , vol.26 , pp. 103-106
    • Baran, D.T.1    Bergfeld, M.A.2    Teitelbaum, S.L.3    Avioli, L.V.4
  • 5
    • 0036924729 scopus 로고    scopus 로고
    • Single and combined effects of growth hormone and testosterone administration on measures of body composition, physical performance, mood, sexual function, bone turnover, and muscle gene expression in healthy older men
    • Brill K.T., Weltman A.L., Gentili A., Patrie J.T., Fryburg D.A., Hanks J.B., Urban R.J., Veldhuis J.D. Single and combined effects of growth hormone and testosterone administration on measures of body composition, physical performance, mood, sexual function, bone turnover, and muscle gene expression in healthy older men. J. Clin. Endocrinol. Metab. 2002, 87:5649-5657.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 5649-5657
    • Brill, K.T.1    Weltman, A.L.2    Gentili, A.3    Patrie, J.T.4    Fryburg, D.A.5    Hanks, J.B.6    Urban, R.J.7    Veldhuis, J.D.8
  • 9
    • 0026603452 scopus 로고
    • Comparison of androgen regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase gene expression in rodent kidney and accessory sex organs
    • Crozat A., Palvimo J.J., Julkunen M., Jänne O.A. Comparison of androgen regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase gene expression in rodent kidney and accessory sex organs. Endocrinology 1992, 130:1131-1144.
    • (1992) Endocrinology , vol.130 , pp. 1131-1144
    • Crozat, A.1    Palvimo, J.J.2    Julkunen, M.3    Jänne, O.A.4
  • 10
    • 43149125406 scopus 로고    scopus 로고
    • Structural basis for the nuclear import of the human androgen receptor
    • Cutress M.L., Whitaker H.C., Mills I.G., Stewart M., Neal D.E. Structural basis for the nuclear import of the human androgen receptor. J. Cell Sci. 2008, 121:957-968.
    • (2008) J. Cell Sci. , vol.121 , pp. 957-968
    • Cutress, M.L.1    Whitaker, H.C.2    Mills, I.G.3    Stewart, M.4    Neal, D.E.5
  • 13
    • 0033854046 scopus 로고    scopus 로고
    • Aldosterone- and testosterone-mediated intracellular calcium response in skeletal muscle cell cultures
    • Estrada M., Liberona J.L., Miranda M., Jaimovich E. Aldosterone- and testosterone-mediated intracellular calcium response in skeletal muscle cell cultures. Am. J. Physiol. Endocrinol. Metab. 2000, 279:E132-E139.
    • (2000) Am. J. Physiol. Endocrinol. Metab. , vol.279
    • Estrada, M.1    Liberona, J.L.2    Miranda, M.3    Jaimovich, E.4
  • 14
    • 0042315340 scopus 로고    scopus 로고
    • Testosterone stimulates intracellular calcium release and mitogen-activated protein kinases via a G protein-coupled receptor in skeletal muscle cells
    • Estrada M., Espinosa A., Muller M., Jaimovich E. Testosterone stimulates intracellular calcium release and mitogen-activated protein kinases via a G protein-coupled receptor in skeletal muscle cells. Endocrinology 2003, 144:3586-3597.
    • (2003) Endocrinology , vol.144 , pp. 3586-3597
    • Estrada, M.1    Espinosa, A.2    Muller, M.3    Jaimovich, E.4
  • 15
    • 0032837376 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay in health and disease
    • Frischmeyer P.A., Dietz H.C. Nonsense-mediated mRNA decay in health and disease. Hum. Mol. Genet. 1999, 8:1893-1900.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 1893-1900
    • Frischmeyer, P.A.1    Dietz, H.C.2
  • 16
    • 0346656465 scopus 로고    scopus 로고
    • Androgens promote maturation and signaling in mouse oocytes independent of transcription: a release of inhibition model for mammalian oocyte meiosis
    • Gill A., Jamnongjit M., Hammes S.R. Androgens promote maturation and signaling in mouse oocytes independent of transcription: a release of inhibition model for mammalian oocyte meiosis. Mol. Endocrinol. 2004, 18:97-104.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 97-104
    • Gill, A.1    Jamnongjit, M.2    Hammes, S.R.3
  • 17
    • 0033304579 scopus 로고    scopus 로고
    • Spermatogenesis without gonadotropins: maintenance has a lower testosterone threshold than initiation
    • Handelsman D.J., Spaliviero J.A., Simpson J.M., Allan C.M., Singh J. Spermatogenesis without gonadotropins: maintenance has a lower testosterone threshold than initiation. Endocrinology 1999, 140:3938-3946.
    • (1999) Endocrinology , vol.140 , pp. 3938-3946
    • Handelsman, D.J.1    Spaliviero, J.A.2    Simpson, J.M.3    Allan, C.M.4    Singh, J.5
  • 20
    • 0036795423 scopus 로고    scopus 로고
    • An estrogen receptor (ER)α deoxyribonucleic acid-binding domain knock-in mutation provides evidence for nonclassical ER pathway signaling in vivo
    • Jakacka M., Ito M., Martinson F., Ishikawa T., Lee E.J., Jameson J.L. An estrogen receptor (ER)α deoxyribonucleic acid-binding domain knock-in mutation provides evidence for nonclassical ER pathway signaling in vivo. Mol. Endocrinol. 2002, 16:2188-2201.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 2188-2201
    • Jakacka, M.1    Ito, M.2    Martinson, F.3    Ishikawa, T.4    Lee, E.J.5    Jameson, J.L.6
  • 21
    • 0029098252 scopus 로고
    • Androgen receptor-mediated transcriptional regulation in the absence of direct interaction with a specific DNA element
    • Kallio P.J., Poukka H., Moilanen A., Jänne O.A., Palvimo J.J. Androgen receptor-mediated transcriptional regulation in the absence of direct interaction with a specific DNA element. Mol. Endocrinol. 1995, 9:1017-1028.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 1017-1028
    • Kallio, P.J.1    Poukka, H.2    Moilanen, A.3    Jänne, O.A.4    Palvimo, J.J.5
  • 24
    • 0038819062 scopus 로고    scopus 로고
    • Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids
    • Kousteni S., Han L., Chen J.R., Almeida M., Plotkin L.I., Bellido T., Manolagas S.C. Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids. J. Clin. Invest. 2003, 111:1651-1664.
    • (2003) J. Clin. Invest. , vol.111 , pp. 1651-1664
    • Kousteni, S.1    Han, L.2    Chen, J.R.3    Almeida, M.4    Plotkin, L.I.5    Bellido, T.6    Manolagas, S.C.7
  • 27
    • 20044369200 scopus 로고    scopus 로고
    • Insulin and leptin resistance with hyperleptinemia in mice lacking androgen receptor
    • Lin H.Y., Xu Q., Yeh S., Wang R.S., Sparks J.D., Chang C. Insulin and leptin resistance with hyperleptinemia in mice lacking androgen receptor. Diabetes 2005, 54:1717-1725.
    • (2005) Diabetes , vol.54 , pp. 1717-1725
    • Lin, H.Y.1    Xu, Q.2    Yeh, S.3    Wang, R.S.4    Sparks, J.D.5    Chang, C.6
  • 29
    • 0028843242 scopus 로고
    • Abnormal androgen receptor binding affinity in subjects with Kennedy's disease (spinal and bulbar muscular atrophy)
    • MacLean H.E., Choi W.T., Rekaris G., Warne G.L., Zajac J.D. Abnormal androgen receptor binding affinity in subjects with Kennedy's disease (spinal and bulbar muscular atrophy). J. Clin. Endocrinol. Metab. 1995, 80:508-516.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 508-516
    • MacLean, H.E.1    Choi, W.T.2    Rekaris, G.3    Warne, G.L.4    Zajac, J.D.5
  • 34
    • 29744441949 scopus 로고    scopus 로고
    • Genomic actions of the androgen receptor are required for normal male sexual differentiation in a mouse model
    • Notini A.J., Davey R.A., McManus J.F., Bate K.L., Zajac J.D. Genomic actions of the androgen receptor are required for normal male sexual differentiation in a mouse model. J. Mol. Endocrinol. 2005, 35:547-555.
    • (2005) J. Mol. Endocrinol. , vol.35 , pp. 547-555
    • Notini, A.J.1    Davey, R.A.2    McManus, J.F.3    Bate, K.L.4    Zajac, J.D.5
  • 39
    • 0026643472 scopus 로고
    • Complete androgen insensitivity due to deletion of exon C of the androgen receptor gene highlights the functional importance of the second zinc finger of the androgen receptor in vivo
    • Quigley C.A., Evans B.A., Simental J.A., Marschke K.B., Sar M., Lubahn D.B., Davies P., Hughes I.A., Wilson E.M., French F.S. Complete androgen insensitivity due to deletion of exon C of the androgen receptor gene highlights the functional importance of the second zinc finger of the androgen receptor in vivo. Mol. Endocrinol. 1992, 6:1103-1112.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1103-1112
    • Quigley, C.A.1    Evans, B.A.2    Simental, J.A.3    Marschke, K.B.4    Sar, M.5    Lubahn, D.B.6    Davies, P.7    Hughes, I.A.8    Wilson, E.M.9    French, F.S.10
  • 41
    • 0029793329 scopus 로고    scopus 로고
    • Androgen receptor-Ets protein interaction is a novel mechanism for steroid hormone-mediated down-modulation of matrix metalloproteinase expression
    • Schneikert J., Peterziel H., Defossez P.A., Klocker H., Launoit Y., Cato A.C. Androgen receptor-Ets protein interaction is a novel mechanism for steroid hormone-mediated down-modulation of matrix metalloproteinase expression. J. Biol. Chem. 1996, 271:23907-23913.
    • (1996) J. Biol. Chem. , vol.271 , pp. 23907-23913
    • Schneikert, J.1    Peterziel, H.2    Defossez, P.A.3    Klocker, H.4    Launoit, Y.5    Cato, A.C.6
  • 42
    • 0034751519 scopus 로고    scopus 로고
    • Clinical review 137: sexual dimorphism in skeletal size, density, and strength
    • Seeman E. Clinical review 137: sexual dimorphism in skeletal size, density, and strength. J. Clin. Endocrinol. Metab. 2001, 86:4576-4584.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 4576-4584
    • Seeman, E.1
  • 44
    • 0242290354 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase/Akt pathway by androgen through interaction of p85α, androgen receptor, and Src
    • Sun M., Yang L., Feldman R.I., Sun X.M., Bhalla K.N., Jove R., Nicosia S.V., Cheng J.Q. Activation of phosphatidylinositol 3-kinase/Akt pathway by androgen through interaction of p85α, androgen receptor, and Src. J. Biol. Chem. 2003, 278:42992-43000.
    • (2003) J. Biol. Chem. , vol.278 , pp. 42992-43000
    • Sun, M.1    Yang, L.2    Feldman, R.I.3    Sun, X.M.4    Bhalla, K.N.5    Jove, R.6    Nicosia, S.V.7    Cheng, J.Q.8
  • 45
    • 4944237502 scopus 로고    scopus 로고
    • Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence
    • Unni E., Sun S., Nan B., McPhaul M.J., Cheskis B., Mancini M.A., Marcelli M. Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence. Cancer Res. 2004, 64:7156-7168.
    • (2004) Cancer Res. , vol.64 , pp. 7156-7168
    • Unni, E.1    Sun, S.2    Nan, B.3    McPhaul, M.J.4    Cheskis, B.5    Mancini, M.A.6    Marcelli, M.7
  • 47
    • 33645329097 scopus 로고    scopus 로고
    • Relative impact of androgen and estrogen receptor activation in the effects of androgens on trabecular and cortical bone in growing male mice: a study in the androgen receptor knockout mouse model
    • Venken K., De Gendt K., Boonen S., Ophoff J., Bouillon R., Swinnen J.V., Verhoeven G., Vanderschueren D. Relative impact of androgen and estrogen receptor activation in the effects of androgens on trabecular and cortical bone in growing male mice: a study in the androgen receptor knockout mouse model. J. Bone Miner. Res. 2006, 21:576-585.
    • (2006) J. Bone Miner. Res. , vol.21 , pp. 576-585
    • Venken, K.1    De Gendt, K.2    Boonen, S.3    Ophoff, J.4    Bouillon, R.5    Swinnen, J.V.6    Verhoeven, G.7    Vanderschueren, D.8
  • 48
    • 49149119954 scopus 로고    scopus 로고
    • Targeting of androgen receptor in bone reveals a lack of androgen anabolic action and inhibition of osteogenesis: a model for compartment-specific androgen action in the skeleton
    • Wiren K.M., Semirale A.A., Zhang X.W., Woo A., Tommasini S.M., Price C., Schaffler M.B., Jepsen K.J. Targeting of androgen receptor in bone reveals a lack of androgen anabolic action and inhibition of osteogenesis: a model for compartment-specific androgen action in the skeleton. Bone 2008, 43:440-451.
    • (2008) Bone , vol.43 , pp. 440-451
    • Wiren, K.M.1    Semirale, A.A.2    Zhang, X.W.3    Woo, A.4    Tommasini, S.M.5    Price, C.6    Schaffler, M.B.7    Jepsen, K.J.8
  • 49
    • 0037396460 scopus 로고    scopus 로고
    • Androgens and coronary artery disease
    • Wu F.C., von Eckardstein A. Androgens and coronary artery disease. Endocr. Rev. 2003, 24:183-217.
    • (2003) Endocr. Rev. , vol.24 , pp. 183-217
    • Wu, F.C.1    von Eckardstein, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.