Arthropathy in long-term cured acromeagaly is characterised by osteophytes without joint space narrowing: A comparison with generalised osteoarthritis

Annals of the Rheumatic Diseases

Volumn 70, Issue 2, 2011, Pages 320-325

  Wassenaar, M J E ^a   Biermasz, N R ^a   Bijsterbosch, J ^a   Pereira, A M ^a   Meulenbelt, I ^a   Smit, J W A ^a   Roelfsema, F ^a   Kroon, H M ^a   Romijn, J A ^a   Kloppenburg, M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN C;

ACROMEGALY; ADULT; ARTICLE; BODY MASS; CONTROLLED STUDY; FEMALE; FUNCTIONAL DISEASE; GROWTH HORMONE BLOOD LEVEL; HIP RADIOGRAPHY; HUMAN; JOINT CAVITY; KNEE RADIOGRAPHY; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; OSTEOPHYTE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SCORING SYSTEM; SELF REPORT;

ACROMEGALY; ADULT; AGED; CROSS-SECTIONAL STUDIES; DISABILITY EVALUATION; FEMALE; HIP JOINT; HUMANS; KNEE JOINT; MALE; MIDDLE AGED; OSTEOARTHRITIS, HIP; OSTEOARTHRITIS, KNEE; OSTEOPHYTE;

EID: 78751701848     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2010.131698     Document Type: Article

References (27)

1. Felson DT, Lawrence RC, Dieppe PA, et al. Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med 2000 ; 133:635-46.
2. Biermasz NR, Pereira AM, Smit JW, et al. Morbidity after long-term remission for acromegaly: persisting joint-related complaints cause reduced quality of life. J Clin Endocrinol Metab 2005 ; 90:2731-9.
3. Bluestone R, Bywaters EG, Hartog M, et al. Acromegalic arthropathy. Ann Rheum Dis 1971 ; 30:243-58.
4. Colao A, Marzullo P, Vallone G, et al. Ultrasonographic evidence of joint thickening reversibility in acromegalic patients treated with lanreotide for 12 months. Clin Endocrinol (Oxf) 1999;51:611-18.
5. Dons RF, Rosselet P, Pastakia B, et al. Arthropathy in acromegalic patients before and after treatment: a long-term follow-up study. Clin Endocrinol (Oxf) 1988;28:515-24.
6. Layton MW, Fudman EJ, Barkan A, et al. Acromegalic arthropathy. Characteristics and response to therapy. Arthritis Rheum 1988;31:1022-7.
7. Scarpa R, De Brasi D, Pivonello R, et al. Acromegalic axial arthropathy: a clinical case-control study. J Clin Endocrinol Metab 2004;89:598-603. (Pubitemid 38269864)
8. Wassenaar MJ, Biermasz NR, van Duinen N, et al. High prevalence of arthropathy, according to the definitions of radiological and clinical osteoarthritis, in patients with long-term cure of acromegaly: a case-control study. Eur J Endocrinol 2009;160:357-65.
9. Maor G, Hochberg Z, Silbermann M. Insulin-like growth factor I accelerates proliferation and differentiation of cartilage progenitor cells in cultures of neonatal mandibular condyles. Acta Endocrinol 1993;128:56-64. (Pubitemid 23055242)
10. Tsukazaki T, Usa T, Matsumoto T, et al. Effect of transforming growth factor-beta on the insulin-like growth factor-I autocrine/paracrine axis in cultured rat articular chondrocytes. Exp Cell Res 1994;215:9-16.
11. Schalkwijk J, Joosten LA, van den Berg WB, et al. Insulin-like growth factor stimulation of chondrocyte proteoglycan synthesis by human synovial fluid. Arthritis Rheum 1989;32:66-71. (Pubitemid 19034926)
12. Guenther HL, Guenther HE, Froesch ER, et al. Effect of insulin-like growth factor on collagen and glycosaminoglycan synthesis by rabbit articular chondrocytes in culture. Experientia 1982 ; 38:979-81.
13. Giustina A, Mazziotti G, Canalis E. Growth hormone, insulin-like growth factors, and the skeleton. Endocr Rev 2008;29:535-59.
14. Riyazi N, Meulenbelt I, Kroon HM, et al. Evidence for familial aggregation of hand, hip, and spine but not knee osteoarthritis in siblings with multiple joint involvement: the GARP study. Ann Rheum Dis 2005;64:438-43.
15. Bellamy N, Buchanan WW, Goldsmith CH, et al. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 1988;15:1833-40. (Pubitemid 19037656)
16. Peterfy C, Li J, Zaim S, et al. Comparison of fixed-flexion positioning with fluoroscopic semi-flexed positioning for quantifying radiographic joint-space width in the knee:test-retest reproducibility. Skeletal Radiol 2003;32:128-32.
17. Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957;16:494-502.
18. Altman RD, Hochberg M, Murphy WA, Jr, et al. Atlas of individual radiographic features in osteoarthritis. Osteoarthr Cartil 1995;3 Suppl A: 3-70.
19. Botha-Scheepers SA, Watt I, Slagboom E, et al. Influence of familial factors on radiologic disease progression over two years in siblings with osteoarthritis at multiple sites: a prospective longitudinal cohort study. Arthritis Rheum 2007;57:626-32. (Pubitemid 46764053)
20. Cole TJ. The LMS method for constructing normalized growth standards. Eur J Clin Nutr 1990;44:45-60.
21. Rikken B, van Doorn J, Ringeling A, et al. Plasma levels of insulin-like growth factor (IGF)-I, IGF-II and IGF-binding protein-3 in the evaluation of childhood growth hormone deficiency. Horm Res 1998;50:166-76. (Pubitemid 28472846)
22. van der Kraan PM, van den Berg WB. Osteophytes: relevance and biology. Osteoarthr Cartil 2007;15:237-44.
23. Okazaki K, Jingushi S, Ikenoue T, et al. Expression of insulin-like growth factor I messenger ribonucleic acid in developing osteophytes in murine experimental osteoarthritis and in rats inoculated with growth hormone-secreting tumor. Endocrinology 1999;140:4821-30.
24. Barkan A. Acromegalic arthropathy and sleep apnea. J Endocrinol 1997;155 (Suppl 1):S41-4; discussion S45.
25. Chrisman OD. The effect of growth hormone on established cartilage lesions. A presidential address to the Association of Bone and Joint Surgeons, 1974. Clin Orthop Relat Res 1975:232-8.
26. Sledge CB. Growth hormone and articular cartilage. Fed Proc 1973;32:1503-5.
27. Keefe FJ, Lefebvre JC, Egert JR, et al. The relationship of gender to pain, pain behavior, and disability in osteoarthritis patients: the role of catastrophizing. Pain 2000;87:325-34.