Distinct DNA methylation patterns of lysophosphatidic acid receptor genes during rat hepatocarcinogenesis induced by a choline-deficient l-amino acid-defined diet

Archives of Toxicology

Volumn 85, Issue 10, 2011, Pages 1303-1310

  Okabe, Kyoko ^a   Hayashi, Mai ^a   Yoshida, Ikuma ^a   Nishimura, Kazuki ^a   Fukushima, Nobuyuki ^a   Tsujiuchi, Toshifumi ^a  

^a KINKI UNIVERSITY   (Japan)

Author keywords

CDAA diet; Hepatocarcinogenesis; LPA receptor; Methylation; Rat

Indexed keywords

AMINO ACID; BISULFITE; CHOLINE; DNA; GENOMIC DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA EXTRACTION; DNA METHYLATION; FOOD INTAKE; GENE EXPRESSION; HISTOPATHOLOGY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER PARENCHYMA; LYSOPHOSPHATIDIC ACID RECEPTOR 1 GENE; LYSOPHOSPHATIDIC ACID RECEPTOR 2 GENE; LYSOPHOSPHATIDIC ACID RECEPTOR 3 GENE; LYSOPHOSPHATIDIC ACID RECEPTOR GENE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; NUTRITIONAL DEFICIENCY; PRIORITY JOURNAL; RAT; RECEPTOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CHOLINE DEFICIENCY; DIET; DNA METHYLATION; GENE EXPRESSION REGULATION, NEOPLASTIC; LIVER; LIVER NEOPLASMS; MALE; RATS; RATS, INBRED F344; RECEPTORS, LYSOPHOSPHATIDIC ACID;

ANIMALIA; RATTUS;

EID: 80755136567     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0656-7     Document Type: Article

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