Does functional brown adipose tissue play an integral role in pediatric energy balance and metabolism?

Journal of Pediatrics

Volumn 159, Issue 6, 2011, Pages 881-883

  Kohn, Brenda ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; FLUORODEOXYGLUCOSE F 18; GASTROINTESTINAL HORMONE; GHRELIN; INSULIN; LEPTIN; LEPTIN RECEPTOR; NEUROPEPTIDE Y; OSTEOGENIC PROTEIN 1; PROOPIOMELANOCORTIN; UNCOUPLING PROTEIN 1;

ADIPOGENESIS; ADRENERGIC STIMULATION; APPETITE; BONE MATURATION; BROWN ADIPOSE TISSUE; CANCER EPIDEMIOLOGY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; EDITORIAL; ENERGY BALANCE; ENERGY METABOLISM; FEMALE; HUMAN; INSULIN SENSITIVITY; LIPID METABOLISM; LIVER FUNCTION; MALE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUBERTY; REPRODUCTION; SYMPATHETIC INNERVATION; THERMOGENESIS;

ADIPOSE TISSUE, BROWN; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; MALE; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS;

EID: 80755132117     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2011.08.021     Document Type: Editorial

References (19)

1. M. Stephens, M. Ludgate, and D.A. Rees Brown fat and obesity: the next big thing? Clin Endocrinol 74 2011 661 670
2. A.M. Cypess, S. Lehman, G. Williams, I. Tal, D. Rodman, and A.B. Goldfine Identification and importance of brown adipose tissue in adult humans N Engl J Med 360 2009 1509 1517
3. V. Gilsanz, S.A. Chung, H. Jackson, F. Dorey, and H.H. Hu Functional brown adipose tissue is related to muscle volume in children and teenagers J Pediatr 158 2011 722 726
4. L.A. Drubach, E.L. Palmer III, L.P. Connolly, A. Baker, D. Zurakowski, and A.M. Cypess Pediatric brown adipose tissue: detection, epidemiology, and differences from adults J Pediatr 159 2011 939 941
5. M.S. Styne, and M.M. Grumbach Puberty: ontogeny, neuroendocrinology, physiology, and disorders. Williams textbook of endocrinology S. Melmed, K.S. Polonsky, P.R. Larsen, H.M. Kronenberg, 2011 Saunders Philadelphia, PA 1054 1201
6. S.M. Harlan, D.A. Morgan, K. Agassandian, D.F. Guo, M.D. Cassell, and C.D. Sigmund Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation Circ Res 108 2011 808 812
7. S.L.J. Wijers, P. Schauwen, M.A. van Baak, W.H.M. Saris, and W.D. van Marken Lichtenbelt β- adrenergic receptor blockade does not inhibit cold-induced thermogenesis in humans: possible involvement of brown adipose tissue J Clin Endocrinol Metab 96 2011 E598 E605
8. M. Lopez, L. Varela, M.J. Vasquez, S. Rodriguez-Cuenca, C.R. Gonzalez, and V.R. Velagapudi Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance Nat Med 16 2010 1001 1008
9. M.C. Skarulis, F.S. Celi, E. Mueller, M. Zemskova, R. Malek, and L. Hugendubler Thyroid hormone induced brown adipose tissue and amelioration of diabetes in a patient with extreme insulin resistance J Clin Endocrinol Metab 95 2010 256 262
10. P.T. Chao, Yang, S. Aja, T.H. Moran, and S. Bi Knockdown of NPY expression in the dorsomedial hypothalamus promotes development of brown adipocytes and prevents diet-induced obesity Cell Metab 13 2011 573 583
11. L.P. Kozak Brown fat and the myth of diet-induced thermogenesis Cell Metab 11 2010 263 267
12. P. Seale, B. Bjork, W. Yang, S. Kajimura, S. Chin, and S. Kuang PRDM16 controls a brown fat/ skeletal muscle switch Nature 454 2008 961 967
13. J. Nedergaard, T. Bengtsson, and B. Cannon Unexpected evidence for active brown adipose tissue in adult humans Am J Phys Endocr Metab 293 2007 E444 E452
14. K.A. Virtanen, and P. Nuutila Brown adipose tissue in humans Curr Opin Lipidol 22 2011 49 54
15. D. Tews, and M. Wabitsch Renaissance of brown fat Horm Res Paediatr 75 2011 231 239
16. A.M. Cypess, and C.R. Kahn Brown fat as a therapy for obesity and diabetes Cur Opin Endocr Diab Obes 17 2010 143 149
17. S. Rodriguez-Cuenca, M. Monjo, M. Gianotti, A.M. Proenza, and P. Roca Expression of mitochondrial biogenesis signaling factors in brown adipocytes is influenced specifically by 17-β estradiol, testosterone and progesterone Am J Phys Endocr Metab 292 2007 E340 E346
18. S. Rodriguez-Cuenca, M. Monjo, M. Frontera, M. Gianotti, A.M. Proenza, and P. Roca Sex steroid receptor profile in brown adipose tissue; effects of hormone status Cell Physiol Biochem 20 2007 877 886
19. P. Lee, J.T. Zhao, M.M. Swarbrick, G. Gracie, R. Bova, and J.R. Greenfield High prevalence of brown adipose tissue in adult humans J Clin Endocrinol Metab 96 2011 2450 2455