Anti-inflammatory activity of 6-hydroxy-2,7-dimethoxy-1,4-henanthraquinone from tuberous roots of Yam (Dioscorea batatas) through inhibition of prostaglandin D 2 and leukotriene C 4 production in mouse bone marrow-derived mast cells

Archives of Pharmacal Research

Volumn 34, Issue 9, 2011, Pages 1495-1501

  Jin, Meihua ^a,b   Lu, Yue ^a   Yang, Ju Hye ^a   Jo, Tae Hyung ^c   Park, Young In ^d   Lee, Chong Kil ^e   Park, Sang Jo ^f   Son, Kun Ho ^g   Chang, Hyeun Wook ^a  

^a Yeungnam University   (South Korea)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c Namyang Inc   (South Korea)

^d Korea University   (South Korea)

^e Chungbuk National University   (South Korea)

^f Gyeongsangbuk do Agricultural Research and Extension Services   (South Korea)

^g Andong National University   (South Korea)

Author keywords

6 Hydroxy 2,7 dimethoxy 1,4 phenanthraquinone; Bone marrow derived mast cells; Cyclooxygenase 2, 5 lipoxygenase; Yam

Indexed keywords

6 HYDROXY 2,7 DIMETHOXY 1,4 HENANTHRAQUINONE; ANTIINFLAMMATORY AGENT; ARACHIDONATE 5 LIPOXYGENASE; CYCLOOXYGENASE 2; LEUKOTRIENE C4; PROSTAGLANDIN D2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BONE MARROW; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIOSCOREA BATATAS; DOSE RESPONSE; IC 50; MALE; MAST CELL; MEDICINAL PLANT; MOUSE; NONHUMAN; PLANT ROOT; WESTERN BLOTTING; YAM;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOTTING, WESTERN; BONE MARROW CELLS; CELL SURVIVAL; DIOSCOREA; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; INHIBITORY CONCENTRATION 50; LEUKOTRIENE C4; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; PHENANTHRENES; PLANT TUBERS; PROSTAGLANDIN D2; QUINONES;

EID: 80755125537     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-011-0911-8     Document Type: Article

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