Baicalin inhibits TLR2/4 signaling pathway in rat brain following permanent cerebral ischemia

Inflammation

Volumn 34, Issue 5, 2011, Pages 463-470

  Tu, Xian Kun ^a,b   Yang, Wei Zhong ^a,b   Shi, Song Sheng ^a   Chen, Ye ^c   Wang, Chun Hua ^b   Chen, Chun Mei ^a   Chen, Zhen ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

^b Fujian Neurosurgical Institute   (China)

^c FUJIAN PROVINCIAL HOSPITAL   (China)

Author keywords

Baicalin; Cerebral ischemia; Cyclooxygenase 2; Inducible nitric oxide synthase; Inflammation; Interleukin 1 ; Nuclear factor kappa B; Toll like receptors; Tumor necrosis factor

Indexed keywords

BAICALIN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MESSENGER RNA; NITRIC OXIDE; PROSTAGLANDIN E2; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; MALE; NEUROPROTECTION; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRAIN; BRAIN ISCHEMIA; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; FLAVONOIDS; INFARCTION, MIDDLE CEREBRAL ARTERY; INTERLEUKIN-1BETA; MALE; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 80655146260     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-010-9254-8     Document Type: Article

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