Toll-like receptor 4 potentiates Ca 2+-dependent secretion of electrolytes from swine tracheal glands

American Journal of Respiratory Cell and Molecular Biology

Volumn 45, Issue 5, 2011, Pages 1101-1110

  Murakami, Koji ^a   Tamada, Tsutomu ^a   Nara, Masayuki ^a   Muramatsu, Soshi ^a   Kikuchi, Toshiaki ^a   Kanehira, Masahiko ^a   Maruyama, Yoshio ^a   Ebina, Masahito ^a   Nukiwa, Toshihiro ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

cGMP dependent protein kinase; Clca; LPS; Nitric oxide; Patch clamp

Indexed keywords

ACETYLCHOLINE; CALCIUM; CYCLIC GMP; CYCLIC GUANOSINE MONOPHOSPHATE DEPENDENT PROTEIN KINASE INHIBITOR; ELECTROLYTE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PEPTIDOGLYCAN; PROTEIN KINASE INHIBITOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ACINAR CELL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ELECTROLYTE TRANSPORT; IMMUNOFLUORESCENCE; ION CURRENT; NONHUMAN; PATCH CLAMP; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SWINE; TRACHEA;

ACETYLCHOLINE; ACINAR CELLS; ANIMALS; CALCIUM; CYCLIC GMP-DEPENDENT PROTEIN KINASES; ELECTROLYTES; ENZYME INHIBITORS; ION CHANNELS; LIPOPOLYSACCHARIDES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SWINE; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TRACHEA;

SUIDAE;

EID: 80555157595     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2011-0020OC     Document Type: Article

References (39)

1. Basbaum CB, Jany B, Finkbeiner WE. The serous cell. Annu Rev Physiol 1990;52:97-113. (Pubitemid 20103529)
2. Widdicombe JH, Bastacky SJ, Wu DX, Lee CY. Regulation of depth and composition of airway surface liquid. Eur Respir J 1997;10:2892-2897. (Pubitemid 28052807)
3. Knowles MR, Boucher RC. Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Invest 2002;109:571-577. (Pubitemid 34204834)
4. Fahy JV, Dickey BF. Medical progress: airway mucus function and dysfunction. N Engl J Med 2010;363:2233-2247.
5. Boucher RC. Human airway ion transport: part one. Am J Respir Crit Care Med 1994;150:271-281.
6. 2- induced bronchitis in rabbit. J Clin Invest 1997;99:1651-1661.
7. Quinton PM. Composition and control of secretions from tracheal bronchial submucosal glands. Nature 1979;279:551-552. (Pubitemid 10232470)
8. Ballard ST, Spadafora D. Fluid secretion by submucosal glands of the tracheobronchial airways. Respir Physiol Neurobiol 2007;159:271-277. (Pubitemid 350116735)
9. 2+-stimulated fluid secretion by porcine bronchial submucosal gland serous acinar cells. Am J Physiol Lung Cell Mol Physiol 2010;298:L210-L231.
10. Joo NS, Cho HJ, Khansaheb M, Wine JJ. Hyposecretion of fluid from tracheal submucosal glands of CFTR-deficient pigs. J Clin Invest 2010;120:3161-3166.
11. Pilette C, Ouadrhiri Y, Godding V, Vaerman JP, Sibille Y. Lung mucosal immunity: immunoglobulin-A revisited. Eur Respir J 2001;18:571-588. (Pubitemid 32895645)
12. Green FH, Williams DJ, James A, McPhee LJ, Mitchell I, Mauad T. Increased myoepithelial cells of bronchial submucosal glands in fatal asthma. Thorax 2010;65:32-38.
13. Tamada T, Nara M, Kanatsuka H, Nagaoka M, Koshida R, Tamura G, Hattori T. A potentiating effect of endogenous NO in the physiologic secretion from airway submucosal glands. Am J Respir Cell Mol Biol 2007;37:357-365. (Pubitemid 350067615)
14. 3 receptors control chloride current in airway gland acinar cells. Am J Physiol 1994;267:L152-L158.
15. Irokawa T, Sasaki T, Shimura S, Sasamori K, Oshiro T, Nara M, Tamada T, Shirato K. Cholinomimetic action of macrolide antibiotics on airway gland electrolyte secretion. Am J Physiol 1999;276:L951-L957. (Pubitemid 29321172)
16. Tamada T, Sasaki T, Saitoh H, Ohkawara Y, Irokawa T, Sasamori K, Oshiro T, Tamura G, Shimura S, Shirato K. A novel function of thyrotropin as a potentiator of electrolyte secretion from the tracheal gland. Am J Respir Cell Mol Biol 2000;22:566-573. (Pubitemid 30319543)
17. 2+-dependent chloride transport. J Biol Chem 2009;284:28698-28703.
18. Iwase N, Sasaki T, Oshiro T, Tamada T, Nara M, Sasamori K, Hattori T, Shirato K, Maruyama Y. Differential effect of epidermal growth factor on serous and mucous cells in porcine airway submucosal gland. Respir Physiol Neurobiol 2002;132:307-319.
19. 2+-mobilizing second messenger, operates in submucosal gland acinar cells. Am J Physiol Lung Cell Mol Physiol 2004;287:L69-L78.
20. Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006;124:783-801. (Pubitemid 43261452)
21. Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010;11:373-384.
22. Sha Q, Truong-Tran AQ, Plitt JR, Beck LA, Schleimer RP. Activation of airway epithelial cells by Toll-like receptor agonists. Am J Respir Cell Mol Biol 2004;31:358-364. (Pubitemid 39180307)
23. Maris NA, Dessing MC, de Vos AF, Bresser P, van der Zee JS, Jansen HM, Spek CA, van der Poll T. Toll-like receptor mRNA levels in alveolar macrophages after inhalation of endotoxin. Eur Respir J 2006;28:622-626. (Pubitemid 44794679)
24. Moue M, Tohno M, Shimazu T, Kido T, Aso H, Saito T, Kitazawa H. Toll-like receptor 4 and cytokine expression involved in functional immune response in an originally established porcine intestinal epitheliocyte cell line. Biochim Biophys Acta 2008;1780:134-144.
25. Akiyama T, Ogawara H. Use and specificity of genistein as inhibitor of protein-tyrosine kinases. Methods Enzymol 1991;201:362-370.
26. Uehara Y, Fukazawa H. Use and selectivity of herbimycin A as inhibitor of protein-tyrosine kinases. Methods Enzymol 1991;201:370-379.
27. - cotransport via PTK-dependent mechanisms in human airway epithelium. Am J Respir Cell Mol Biol 2009;41:688-695.
28. Nadel JA, Davis B. Parasympathetic and sympathetic regulation of secretion from submucosal glands in airways. Fed Proc 1980;39:3075-3079. (Pubitemid 11214764)
29. Tom-Moy M, Basbaum CB, Nadel JA. Localization and release of lysozyme from ferret trachea: effects of adrenergic and cholinergic drugs. Cell Tissue Res 1983;228:549-562. (Pubitemid 13148703)
30. Wine JJ. Parasympathetic control of airway submucosal glands: central reflexes and the airway intrinsic nervous system. Auton Neurosci 2007;133:35-54. (Pubitemid 46505121)
31. Liu X, Engelhardt JF. The glandular stem/progenitor cell niche in airway development and repair. Proc Am Thorac Soc 2008;5:682-688.
32. Delavoie F, Molinari M, Milliot M, Zahm JM, Coraux C, Michel J, Balossier G. Salmeterol restores secretory functions in cystic fibrosis airway submucosal gland serous cells. Am J Respir Cell Mol Biol 2009;40:388-397.
33. Joo NS, Wine JJ, Cuthbert AW. Lubiprostone stimulates secretion from tracheal submucosal glands of sheep, pigs, and humans. Am J Physiol Lung Cell Mol Physiol 2009;296:L811-L824.
34. Cho HJ, Joo NS, Wine JJ. Mucus secretion from individual submucosal glands of the ferret trachea. Am J Physiol Lung Cell Mol Physiol 2010;299:L124-L136.
35. +] and pH but elevated viscosity. Proc Natl Acad Sci USA 2001;98:8119-8123.
36. Joo NS, Wu JV, Krouse ME, Saenz Y, Wine JJ. Optical method for quantifying rates of mucus secretion from single submucosal glands. Am J Physiol Lung Cell Mol Physiol 2001;281:L458-L468.
37. Joo NS, Saenz Y, Krouse ME, Wine JJ. Mucus secretion from single submucosal glands of pig: stimulation by carbachol and vasoactive intestinal peptide. J Biol Chem 2002;277:28167-28175. (Pubitemid 34966770)
38. Koff JL, Shao MX, Ueki IF, Nadel JA. Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium. Am J Physiol Lung Cell Mol Physiol 2008;294:L1068-L1075.
39. Zhang G, Han J, Welch EJ, Ye RD, Voyno-Yasenetskaya TA, Malik AB, Du X, Li Z. Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway. J Immunol 2009;182:7997-8004.