Body weight reducing effect of oral boric acid intake

International Journal of Medical Sciences

Volumn 8, Issue 8, 2011, Pages 653-658

  Aysan, Erhan ^a   Sahin, Fikrettin ^b   Telci, Dilek ^b   Yalvac, Mehmet Emir ^b   Emre, Sinem Hocaoglu ^c   Karaca, Cetin ^d   Muslumanoglu, Mahmut ^a  

^a BEZMIALEM VAKIF UNIVERSITY   (Turkey)

^b YEDITEPE UNIVERSITY   (Turkey)

^c Istanbul Educational and Research Hospital ^*  (Turkey)

^d ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Body weight; Boric acid; Oral intake

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; AMYLASE; ASPARTATE AMINOTRANSFERASE; BILE ACID; BILIRUBIN; BORIC ACID; CALCIUM; CHOLESTEROL; CREATINE KINASE; CREATINE KINASE MB; CREATININE; DRINKING WATER; HIGH DENSITY LIPOPROTEIN; LACTATE DEHYDROGENASE; LOW DENSITY LIPOPROTEIN; POTASSIUM; PROTEIN; SODIUM; TAP WATER; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; UROBILINOGEN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; AMYLASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; BLOOD LEVEL; BRAIN; CALCIUM BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; COLON; CONCENTRATION RESPONSE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; CREATININE BLOOD LEVEL; FECES ANALYSIS; HISTOPATHOLOGY; INTESTINE; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; LIVER; MOUSE; NONHUMAN; POTASSIUM BLOOD LEVEL; PROTEIN BLOOD LEVEL; SODIUM BLOOD LEVEL; SPLEEN; STOMACH; THYMUS; THYROID GLAND; TRIACYLGLYCEROL BLOOD LEVEL; TRIACYLGLYCEROL LIPASE BLOOD LEVEL; URINE VOLUME; UROBILINOGEN BLOOD LEVEL; WEIGHT GAIN; WEIGHT REDUCTION;

EID: 80555145059     PISSN: 14491907     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijms.8.653     Document Type: Article

References (38)

1. Anderson D, Cunningham W, Lindstrom T. Concentrations and intakes of H, B, S, K, Na, Cl and NaCl in foods. J Food Compost Anal 1994; 7: 59-82.
2. Altieri S, et al. Neutron autoradiography imaging of selective boron uptake in human metastatic tumors. Appl Radiat Isot 2008; 66: 1850-1855.
3. Hunter P. Not boring at all. Boron is the new carbon in the quest for novel drug candidates. EMBO Reports. 2009; 10:125-128.
4. Warrington K. The effects of boric acid and borax on the broad bean and certain other plants. Ann Bol 1923; 37: 629-672.
5. Rossi AF, Miles RD, Damron BL, Flunker LK. Effects of dietary boron suplementation on broilers. Poult Sci 1993; 72: 2124-2130.
6. Skinner JT, McHargue JS. Response of rats to boron supple-ments when fed rations low in potassium. Am J Physiol 1945; 143: 385-390.
7. Wilson JH, Ruszler PL. Effects of boron on growing pullets. Biol Trace Elem Res 1997; 56: 287-294.
8. Wilson JH, Ruszler PL. Long term effects of boron on layer bone strength and production parameters. Br J Poult 1998; 39: 11-15.
9. Armstrong TA, Spears JW, Crenshaw TD, Nielsen FH. Boron supplementation of a semipurified diet for weaning pigs im-proves feed efficiency and bone strength characteristics and al-ters plasma lipid metabolites. J Nutr 2000; 139: 2575-2581.
10. Hunt CD. Biochemical effects of physiological amounts of die-tary boron. J Trace Elem Exp Med 1996; 9: 185-213.
11. Nielsen FH, Hunt CD, Mullen LM, Hunt JR. Effects of dietary boron on mineral, estrogen, and testosteron metabolism in postmenopausal women. FASEB J 1987;1:394-397.
12. Almond JB, Cohen GM. Theproteasome: a novel target for cancer chemotherapy. Leukaemia 2002; 16: 433-443.
13. Dugger W. Boron in plant metabolism. In: Lauchli A, Bielesk R, eds. Encyclopedia of plant physiology, inorganic plant nutri-tion; Vol 15. Berlin: Springer Verlag. 1983: 626-650.
14. Deitrich R. Diphosphopyridine nucleotide-linked aldehyde dehydrogenase III. Sulfhydril characteristics of the enzyme. Arch Biochem Biophys 1967; 119: 253-263.
15. Roush A, Norris E. The inhibition of xanthine oxidase by bo-rates. Arch Biochem Biophys 1950; 29: 344-347.
16. Strittmatter P. Reversible direct hydrogen transfer from re-duced pyridine nucleotides to cytocrome b5 reductase. J Biol Chem 1964; 239: 3043-3050.
17. Johnson S, Smith K. The interaction of borate and sulfite with pyridine nucleotides. Biochemistry 1976; 15: 553-559.
18. Blevins DG, Lukaszewski KM. Proposed physiologic function of boron in plants pertinent to animal and human metabolism. Environ Health Perspect 1994; 102: 31-33.
19. Goldbach HE, Hartmann D, Rotzer T. Boron is required for the stimulation of the ferricyanide-induced proton release by auxin in suspension-cultured cells of Daucus carota and Lycopersicon esculentum. Physiol Plant 1990; 80: 114-118.
20. Ferrol N, Rodriguez-Rosales MP, Roldan M, Belver A, Donaire JP. Characterization of proton extrusion in sunflower cell cul-tures. Rev Esp Fisiol 1992; 48: 22-27.
21. Roldan M, Belver A, Rodriguez-Rosales MP, Ferrol N, Donaire JP. In vivo and in vitro effects of boron on the plasma mem-brane proton pump of sunflower roots. Physiol Plant 1992; 84: 49-54.
22. Belver A, Donaire JP. Partial purification of soluble lipoxygen-ase of sunflower cotyledons: action of boron on the enzyme and lipid constituents. Z Pflanzenphysiol 1983; 109: 309-317
23. Loomis WD, Durst RW. Chemistry and biology of boron. Bio-Factors 1992; 2: 229-239.
24. Barr R. The possible role of redox-associated proteins in growth of plant cells. J Bioenerg Biomembr 1991; 23: 443-467.
25. Morre DJ, Brightman AO. NADH oxidase of plasma mem-branes. J Bioenerg Biomembr 1991; 23: 469-489.
26. Hunt C, Nielsen F. Interaction between boron and cholecalcif-erol in the chick. In: Trace element metabolism in man and animals-vol 4. Gawthorne J, White C, eds. Canberra: Australian Academy of Science, 1981: 597-600.
27. NIH. Toxicology and carcinogenesis studies of boric acid (CAS no. 10043-35-3) in B6C3F1 mice (food studies). Research Trian-gle Park, NC: US Department of Health and Human Services, Public Health Service, National Institutes of Health, National Toxicology Program. 1987.
28. Weir RJJr, Fisher RS. Toxicologic studies on borax and boric acid. Toxicol Appl Pharmacol. 1972; 23: 351-364.
29. Benson WH, Birge WJ, Dorough HW. Absence of mutagenic activity of sodium borate (borax) and boric acid in the Salmo-nella preincubation test. Environ Toxicol Chem 1984; 3: 209-214.
30. Landolph JR. Cytotoxicity and negligible genotoxicity of borax and borax ores to cultured mammalian cells. Am J Ind Med 1985; 7: 31-43.
31. Willig H, Curtze A. Animal experiments in the therapy of obe-sity with boric acid. Dtsch Med J. 1952; 15: 483-485.
32. Lee IP, Sherins RJ, Dixon RL. Evidence for induction of germi-nal aplasia in male rats by environmental exposure to boron. Toxicol Appl Pharmacol, 1978; 45: 577-590.
33. Guaraldi F, Pagotto U, Pasquali R. Predictors of weight loss and maintenance in patients treated with antiobesity drugs. Diabe-tes Metab Syndr Obes. 2011;4:229-43.
34. Lafontan M, Langin D. Lipolysis and lipid mobilization in human adipose tissue. Prog Lipid Res 2009;48:275-297.
35. Jensen MD, Caruso M, Heiling V, Miles JM. Insulin regulation of lipolysis in nondiabetic and IDDM subjects. Diabetes 1989;38:1595-1601.
36. Lewis GF, Uffelman KD, Szeto LW, Steiner G. Effects of acute hyperinsulinemia on VLDL triglyceride and VLDL apoB pro-duction in normal weight and obese individuals. Diabetes 1993;42:833-842.
37. Cinti S, et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Li-pid Res. 2005; 46: 2347-2355.
38. Nishimura S, et al. Adipogenesis in obesity requires close in-terplay between differentiating adipocytes, stromal cells, and blood vessels. Diabetes. 2007; 56: 1517-1526.