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Volumn 44, Issue 3, 2011, Pages 437-450

Protein phosphatase 2A controls the order and dynamics of cell-cycle transitions

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN E; CYCLINE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN TYROSINE PHOSPHATASE;

EID: 80555135904     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2011.10.007     Document Type: Article
Times cited : (42)

References (50)
  • 1
    • 73949151141 scopus 로고    scopus 로고
    • The M phase kinase Greatwall (Gwl) promotes inactivation of PP2A/B55delta, a phosphatase directed against CDK phosphosites
    • Castilho P.V., Williams B.C., Mochida S., Zhao Y., Goldberg M.L. The M phase kinase Greatwall (Gwl) promotes inactivation of PP2A/B55delta, a phosphatase directed against CDK phosphosites. Mol. Biol. Cell 2009, 20:4777-4789.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 4777-4789
    • Castilho, P.V.1    Williams, B.C.2    Mochida, S.3    Zhao, Y.4    Goldberg, M.L.5
  • 2
    • 0037174861 scopus 로고    scopus 로고
    • Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex
    • Chou D.M., Petersen P., Walter J.C., Walter G. Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex. J. Biol. Chem. 2002, 277:40520-40527.
    • (2002) J. Biol. Chem. , vol.277 , pp. 40520-40527
    • Chou, D.M.1    Petersen, P.2    Walter, J.C.3    Walter, G.4
  • 3
    • 0027538301 scopus 로고
    • Dephosphorylation of cdc25-C by a type-2A protein phosphatase: specific regulation during the cell cycle in Xenopus egg extracts
    • Clarke P.R., Hoffmann I., Draetta G., Karsenti E. Dephosphorylation of cdc25-C by a type-2A protein phosphatase: specific regulation during the cell cycle in Xenopus egg extracts. Mol. Biol. Cell 1993, 4:397-411.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 397-411
    • Clarke, P.R.1    Hoffmann, I.2    Draetta, G.3    Karsenti, E.4
  • 4
    • 0024397415 scopus 로고
    • The structure and regulation of protein phosphatases
    • Cohen P. The structure and regulation of protein phosphatases. Annu. Rev. Biochem. 1989, 58:453-508.
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 453-508
    • Cohen, P.1
  • 5
    • 78650842310 scopus 로고    scopus 로고
    • Driving the cell cycle with a minimal CDK control network
    • Coudreuse D., Nurse P. Driving the cell cycle with a minimal CDK control network. Nature 2010, 468:1074-1079.
    • (2010) Nature , vol.468 , pp. 1074-1079
    • Coudreuse, D.1    Nurse, P.2
  • 6
    • 0025284348 scopus 로고
    • Completion of DNA replication is monitored by a feedback system that controls the initiation of mitosis in vitro: studies in Xenopus
    • Dasso M., Newport J.W. Completion of DNA replication is monitored by a feedback system that controls the initiation of mitosis in vitro: studies in Xenopus. Cell 1990, 61:811-823.
    • (1990) Cell , vol.61 , pp. 811-823
    • Dasso, M.1    Newport, J.W.2
  • 7
    • 70149108086 scopus 로고    scopus 로고
    • Essential global role of CDC14 in DNA synthesis revealed by chromosome underreplication unrecognized by checkpoints in cdc14 mutants
    • Dulev S., de Renty C., Mehta R., Minkov I., Schwob E., Strunnikov A. Essential global role of CDC14 in DNA synthesis revealed by chromosome underreplication unrecognized by checkpoints in cdc14 mutants. Proc. Natl. Acad. Sci. USA 2009, 106:14466-14471.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 14466-14471
    • Dulev, S.1    de Renty, C.2    Mehta, R.3    Minkov, I.4    Schwob, E.5    Strunnikov, A.6
  • 8
    • 0025058599 scopus 로고
    • Cdc2 H1 kinase is negatively regulated by a type 2A phosphatase in the Xenopus early embryonic cell cycle: evidence from the effects of okadaic acid
    • Félix M.A., Cohen P., Karsenti E. Cdc2 H1 kinase is negatively regulated by a type 2A phosphatase in the Xenopus early embryonic cell cycle: evidence from the effects of okadaic acid. EMBO J. 1990, 9:675-683.
    • (1990) EMBO J. , vol.9 , pp. 675-683
    • Félix, M.A.1    Cohen, P.2    Karsenti, E.3
  • 9
    • 0029670828 scopus 로고    scopus 로고
    • A single fission yeast mitotic cyclin B p34cdc2 kinase promotes both S-phase and mitosis in the absence of G1 cyclins
    • Fisher D.L., Nurse P. A single fission yeast mitotic cyclin B p34cdc2 kinase promotes both S-phase and mitosis in the absence of G1 cyclins. EMBO J. 1996, 15:850-860.
    • (1996) EMBO J. , vol.15 , pp. 850-860
    • Fisher, D.L.1    Nurse, P.2
  • 10
    • 0035911969 scopus 로고    scopus 로고
    • Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication
    • Furstenthal L., Kaiser B.K., Swanson C., Jackson P.K. Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication. J. Cell Biol. 2001, 152:1267-1278.
    • (2001) J. Cell Biol. , vol.152 , pp. 1267-1278
    • Furstenthal, L.1    Kaiser, B.K.2    Swanson, C.3    Jackson, P.K.4
  • 12
    • 0029039470 scopus 로고
    • Phosphorylation and activation of the Xenopus Cdc25 phosphatase in the absence of Cdc2 and Cdk2 kinase activity
    • Izumi T., Maller J.L. Phosphorylation and activation of the Xenopus Cdc25 phosphatase in the absence of Cdc2 and Cdk2 kinase activity. Mol. Biol. Cell 1995, 6:215-226.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 215-226
    • Izumi, T.1    Maller, J.L.2
  • 13
    • 33947304756 scopus 로고    scopus 로고
    • Substrate competition as a source of ultrasensitivity in the inactivation of Wee1
    • Kim S.Y., Ferrell J.E. Substrate competition as a source of ultrasensitivity in the inactivation of Wee1. Cell 2007, 128:1133-1145.
    • (2007) Cell , vol.128 , pp. 1133-1145
    • Kim, S.Y.1    Ferrell, J.E.2
  • 14
    • 0024996931 scopus 로고
    • Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle
    • Kinoshita N., Ohkura H., Yanagida M. Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle. Cell 1990, 63:405-415.
    • (1990) Cell , vol.63 , pp. 405-415
    • Kinoshita, N.1    Ohkura, H.2    Yanagida, M.3
  • 15
    • 0027176793 scopus 로고
    • Negative regulation of mitosis by the fission yeast protein phosphatase ppa2
    • Kinoshita N., Yamano H., Niwa H., Yoshida T., Yanagida M. Negative regulation of mitosis by the fission yeast protein phosphatase ppa2. Genes Dev. 1993, 7:1059-1071.
    • (1993) Genes Dev. , vol.7 , pp. 1059-1071
    • Kinoshita, N.1    Yamano, H.2    Niwa, H.3    Yoshida, T.4    Yanagida, M.5
  • 17
    • 40949152974 scopus 로고    scopus 로고
    • Cdk1 and Cdk2 activity levels determine the efficiency of replication origin firing in Xenopus
    • Krasinska L., Besnard E., Cot E., Dohet C., Méchali M., Lemaitre J.M., Fisher D. Cdk1 and Cdk2 activity levels determine the efficiency of replication origin firing in Xenopus. EMBO J. 2008, 27:758-769.
    • (2008) EMBO J. , vol.27 , pp. 758-769
    • Krasinska, L.1    Besnard, E.2    Cot, E.3    Dohet, C.4    Méchali, M.5    Lemaitre, J.M.6    Fisher, D.7
  • 18
    • 47249098992 scopus 로고    scopus 로고
    • Selective chemical inhibition as a tool to study Cdk1 and Cdk2 functions in the cell cycle
    • Krasinska L., Cot E., Fisher D. Selective chemical inhibition as a tool to study Cdk1 and Cdk2 functions in the cell cycle. Cell Cycle 2008, 7:1702-1708.
    • (2008) Cell Cycle , vol.7 , pp. 1702-1708
    • Krasinska, L.1    Cot, E.2    Fisher, D.3
  • 19
    • 0026719599 scopus 로고
    • Regulation of the cdc25 protein during the cell cycle in Xenopus extracts
    • Kumagai A., Dunphy W.G. Regulation of the cdc25 protein during the cell cycle in Xenopus extracts. Cell 1992, 70:139-151.
    • (1992) Cell , vol.70 , pp. 139-151
    • Kumagai, A.1    Dunphy, W.G.2
  • 21
    • 77954355722 scopus 로고    scopus 로고
    • Constant regulation of both the MPF amplification loop and the Greatwall-PP2A pathway is required for metaphase II arrest and correct entry into the first embryonic cell cycle
    • Lorca T., Bernis C., Vigneron S., Burgess A., Brioudes E., Labbé J.C., Castro A. Constant regulation of both the MPF amplification loop and the Greatwall-PP2A pathway is required for metaphase II arrest and correct entry into the first embryonic cell cycle. J. Cell Sci. 2010, 123:2281-2291.
    • (2010) J. Cell Sci. , vol.123 , pp. 2281-2291
    • Lorca, T.1    Bernis, C.2    Vigneron, S.3    Burgess, A.4    Brioudes, E.5    Labbé, J.C.6    Castro, A.7
  • 22
    • 77951763153 scopus 로고    scopus 로고
    • Periodic cyclin-Cdk activity entrains an autonomous Cdc14 release oscillator
    • Lu Y., Cross F.R. Periodic cyclin-Cdk activity entrains an autonomous Cdc14 release oscillator. Cell 2010, 141:268-279.
    • (2010) Cell , vol.141 , pp. 268-279
    • Lu, Y.1    Cross, F.R.2
  • 23
    • 0031022391 scopus 로고    scopus 로고
    • Cell cycle regulation of the replication licensing system: involvement of a Cdk-dependent inhibitor
    • Mahbubani H.M., Chong J.P., Chevalier S., Thömmes P., Blow J.J. Cell cycle regulation of the replication licensing system: involvement of a Cdk-dependent inhibitor. J. Cell Biol. 1997, 136:125-135.
    • (1997) J. Cell Biol. , vol.136 , pp. 125-135
    • Mahbubani, H.M.1    Chong, J.P.2    Chevalier, S.3    Thömmes, P.4    Blow, J.J.5
  • 24
    • 0242389822 scopus 로고    scopus 로고
    • PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation
    • Margolis S.S., Walsh S., Weiser D.C., Yoshida M., Shenolikar S., Kornbluth S. PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation. EMBO J. 2003, 22:5734-5745.
    • (2003) EMBO J. , vol.22 , pp. 5734-5745
    • Margolis, S.S.1    Walsh, S.2    Weiser, D.C.3    Yoshida, M.4    Shenolikar, S.5    Kornbluth, S.6
  • 26
    • 21044435818 scopus 로고    scopus 로고
    • Differential regulation of Cdc2 and Aurora-A in Xenopus oocytes: a crucial role of phosphatase 2A
    • Maton G., Lorca T., Girault J.A., Ozon R., Jessus C. Differential regulation of Cdc2 and Aurora-A in Xenopus oocytes: a crucial role of phosphatase 2A. J. Cell Sci. 2005, 118:2485-2494.
    • (2005) J. Cell Sci. , vol.118 , pp. 2485-2494
    • Maton, G.1    Lorca, T.2    Girault, J.A.3    Ozon, R.4    Jessus, C.5
  • 27
    • 0032190507 scopus 로고    scopus 로고
    • Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk
    • Mimura S., Takisawa H. Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk. EMBO J. 1998, 17:5699-5707.
    • (1998) EMBO J. , vol.17 , pp. 5699-5707
    • Mimura, S.1    Takisawa, H.2
  • 28
    • 70349210060 scopus 로고    scopus 로고
    • Regulated activity of PP2A-B55 delta is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts
    • Mochida S., Ikeo S., Gannon J., Hunt T. Regulated activity of PP2A-B55 delta is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts. EMBO J. 2009, 28:2777-2785.
    • (2009) EMBO J. , vol.28 , pp. 2777-2785
    • Mochida, S.1    Ikeo, S.2    Gannon, J.3    Hunt, T.4
  • 29
    • 78650366525 scopus 로고    scopus 로고
    • Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis
    • Mochida S., Maslen S.L., Skehel M., Hunt T. Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis. Science 2010, 330:1670-1673.
    • (2010) Science , vol.330 , pp. 1670-1673
    • Mochida, S.1    Maslen, S.L.2    Skehel, M.3    Hunt, T.4
  • 30
    • 34447280859 scopus 로고    scopus 로고
    • Synthesis and use of the protein phosphatase affinity matrices microcystin-sepharose and microcystin-biotin-sepharose
    • Moorhead G.B., Haystead T.A., MacKintosh C. Synthesis and use of the protein phosphatase affinity matrices microcystin-sepharose and microcystin-biotin-sepharose. Methods Mol. Biol. 2007, 365:39-45.
    • (2007) Methods Mol. Biol. , vol.365 , pp. 39-45
    • Moorhead, G.B.1    Haystead, T.A.2    MacKintosh, C.3
  • 31
    • 0028998865 scopus 로고
    • Cell cycle regulation of a Xenopus Wee1-like kinase
    • Mueller P.R., Coleman T.R., Dunphy W.G. Cell cycle regulation of a Xenopus Wee1-like kinase. Mol. Biol. Cell 1995, 6:119-134.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 119-134
    • Mueller, P.R.1    Coleman, T.R.2    Dunphy, W.G.3
  • 32
    • 0028836621 scopus 로고
    • The role of protein phosphorylation in the assembly of a replication competent nucleus: investigations in Xenopus egg extracts using the cyanobacterial toxin microcystin-LR
    • Murphy J., Crompton C.M., Hainey S., Codd G.A., Hutchison C.J. The role of protein phosphorylation in the assembly of a replication competent nucleus: investigations in Xenopus egg extracts using the cyanobacterial toxin microcystin-LR. J. Cell Sci. 1995, 108:235-244.
    • (1995) J. Cell Sci. , vol.108 , pp. 235-244
    • Murphy, J.1    Crompton, C.M.2    Hainey, S.3    Codd, G.A.4    Hutchison, C.J.5
  • 33
    • 0027716813 scopus 로고
    • Numerical analysis of a comprehensive model of M-phase control in Xenopus oocyte extracts and intact embryos
    • Novak B., Tyson J.J. Numerical analysis of a comprehensive model of M-phase control in Xenopus oocyte extracts and intact embryos. J. Cell Sci. 1993, 106:1153-1168.
    • (1993) J. Cell Sci. , vol.106 , pp. 1153-1168
    • Novak, B.1    Tyson, J.J.2
  • 35
    • 33644549654 scopus 로고    scopus 로고
    • Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint
    • Petersen P., Chou D.M., You Z., Hunter T., Walter J.C., Walter G. Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint. Mol. Cell. Biol. 2006, 26:1997-2011.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 1997-2011
    • Petersen, P.1    Chou, D.M.2    You, Z.3    Hunter, T.4    Walter, J.C.5    Walter, G.6
  • 36
    • 0345700833 scopus 로고    scopus 로고
    • Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2
    • Pomerening J.R., Sontag E.D., Ferrell J.E. Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2. Nat. Cell Biol. 2003, 5:346-351.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 346-351
    • Pomerening, J.R.1    Sontag, E.D.2    Ferrell, J.E.3
  • 41
    • 79251534050 scopus 로고    scopus 로고
    • Ultrasensitivity in the Regulation of Cdc25C by Cdk1
    • Trunnell N.B., Poon A.C., Kim S.Y., Ferrell J.E. Ultrasensitivity in the Regulation of Cdc25C by Cdk1. Mol. Cell 2011, 41:263-274.
    • (2011) Mol. Cell , vol.41 , pp. 263-274
    • Trunnell, N.B.1    Poon, A.C.2    Kim, S.Y.3    Ferrell, J.E.4
  • 43
    • 0030720062 scopus 로고    scopus 로고
    • Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A
    • Walsh A.H., Cheng A., Honkanen R.E. Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A. FEBS Lett. 1997, 416:230-234.
    • (1997) FEBS Lett. , vol.416 , pp. 230-234
    • Walsh, A.H.1    Cheng, A.2    Honkanen, R.E.3
  • 44
    • 0032015702 scopus 로고    scopus 로고
    • Regulated chromosomal DNA replication in the absence of a nucleus
    • Walter J., Sun L., Newport J. Regulated chromosomal DNA replication in the absence of a nucleus. Mol. Cell 1998, 1:519-529.
    • (1998) Mol. Cell , vol.1 , pp. 519-529
    • Walter, J.1    Sun, L.2    Newport, J.3
  • 47
    • 78651066539 scopus 로고    scopus 로고
    • The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase
    • Wicky S., Tjandra H., Schieltz D., Yates J., Kellogg D.R. The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase. Mol. Biol. Cell 2011, 22:20-32.
    • (2011) Mol. Biol. Cell , vol.22 , pp. 20-32
    • Wicky, S.1    Tjandra, H.2    Schieltz, D.3    Yates, J.4    Kellogg, D.R.5
  • 48
    • 67349134688 scopus 로고    scopus 로고
    • PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation
    • Wu J.Q., Guo J.Y., Tang W., Yang C.S., Freel C.D., Chen C., Nairn A.C., Kornbluth S. PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation. Nat. Cell Biol. 2009, 11:644-651.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 644-651
    • Wu, J.Q.1    Guo, J.Y.2    Tang, W.3    Yang, C.S.4    Freel, C.D.5    Chen, C.6    Nairn, A.C.7    Kornbluth, S.8
  • 49
    • 33645968394 scopus 로고    scopus 로고
    • Greatwall kinase participates in the Cdc2 autoregulatory loop in Xenopus egg extracts
    • Yu J., Zhao Y., Li Z., Galas S., Goldberg M.L. Greatwall kinase participates in the Cdc2 autoregulatory loop in Xenopus egg extracts. Mol. Cell 2006, 22:83-91.
    • (2006) Mol. Cell , vol.22 , pp. 83-91
    • Yu, J.1    Zhao, Y.2    Li, Z.3    Galas, S.4    Goldberg, M.L.5
  • 50
    • 0032562610 scopus 로고    scopus 로고
    • Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin
    • Zou L., Stillman B. Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. Science 1998, 280:593-596.
    • (1998) Science , vol.280 , pp. 593-596
    • Zou, L.1    Stillman, B.2


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