Mycobacterium tuberculosis Ku can bind to nuclear DNA damage and sensitize mammalian cells to bleomycin sulfate

Mutagenesis

Volumn 26, Issue 6, 2011, Pages 795-803

  Castore, Reneau ^a   Hughes, Cameron ^a   Debeaux, Austin ^a   Sun, Jingxin ^b   Zeng, Cailing ^b   Wang, Shih Ya ^b   Tatchell, Kelly ^c   Shi, Runhua ^a   Lee, Kyung Jong ^b   Chen, David J ^b   Harrison, Lynn ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c Department of Biochemistry and Molecular Biology ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN SULFATE; DOUBLE STRANDED DNA; ENHANCED GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; HYDROGEN PEROXIDE; KU ANTIGEN;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL NUCLEUS; CHEMOSENSITIVITY; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DRUG CYTOTOXICITY; ESCHERICHIA COLI; GENE OVEREXPRESSION; GROWTH RATE; HUMAN; HUMAN CELL; IN VITRO STUDY; LASER; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PROTEIN INTERACTION; RADIOSENSITIVITY; TRANSIENT TRANSFECTION; ULTRAVIOLET RADIATION;

ANIMALS; ANTIGENS, NUCLEAR; BACTERIAL PROTEINS; BLEOMYCIN; CELL LINE; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; DNA DAMAGE; DNA END-JOINING REPAIR; DNA LIGASES; DNA, CIRCULAR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; GREEN FLUORESCENT PROTEINS; HUMANS; MAMMALS; MYCOBACTERIUM TUBERCULOSIS; PLASMIDS; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS;

BACTERIA (MICROORGANISMS); MAMMALIA; MYCOBACTERIUM TUBERCULOSIS;

EID: 80455178850     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/ger049     Document Type: Article

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