Spectral classifier design with ensemble classifiers and misclassification-rejection: Application to elastic-scattering spectroscopy for detection of colonic neoplasia

Journal of Biomedical Optics

Volumn 16, Issue 6, 2011, Pages

  Rodriguez Diaz, Eladio ^a   Castanon, David A ^b   Singh, Satish K ^a,b   Bigioa, Irving J ^a,b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Boston University   (United States)

Author keywords

Colorectal cancer screening; Diagnostic algorithms; Elastic scattering spectroscopy; Endoscopic diagnosis; Ensemble classifiers; Error rejection; Neoplasia; Support vector machines

Indexed keywords

COLORECTAL CANCER; DIAGNOSTIC ALGORITHMS; ELASTIC-SCATTERING SPECTROSCOPY; ENDOSCOPIC DIAGNOSIS; ENSEMBLE CLASSIFIERS; NEOPLASIA; SUPPORT VECTOR;

ALGORITHMS; DISEASES; ENDOSCOPY; FEATURE EXTRACTION; PRINCIPAL COMPONENT ANALYSIS; SUPPORT VECTOR MACHINES;

SCATTERING;

ALGORITHM; ARTICLE; ARTIFICIAL INTELLIGENCE; COLON POLYP; COLON TUMOR; COLONOSCOPY; ELASTOGRAPHY; EQUIPMENT DESIGN; HUMAN; IMAGE PROCESSING; INSTRUMENTATION; METHODOLOGY; PATHOLOGY; PRINCIPAL COMPONENT ANALYSIS; REPRODUCIBILITY;

ALGORITHMS; ARTIFICIAL INTELLIGENCE; COLONIC NEOPLASMS; COLONIC POLYPS; COLONOSCOPY; ELASTICITY IMAGING TECHNIQUES; EQUIPMENT DESIGN; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; PRINCIPAL COMPONENT ANALYSIS; REPRODUCIBILITY OF RESULTS;

EID: 80455176497     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3592488     Document Type: Article

References (61)

1. A. Dhar, K. S. Johnson, M. R. Novelli, S. G. Bown, I. J. Bigio, L. B. Lovat, and S. L. Bloom, "Elastic scattering spectroscopy for the diagnosis of colonic lesions: initial results of a novel optical biopsy technique," Gastrointest. Endosc. 63(2), 257-261 (2006). (Pubitemid 43113194)
2. Z. Ge, K. T. Schomacker, and N. S. Nishioka, "Identification of colonic dysplasia and neoplasia by diffuse reflectance spectroscopy and pattern recognition techniques," Appl. Spectrosc. 52(6), 833-839 (1998). (Pubitemid 128619588)
3. J. R. Mourant, I. J. Bigio, J. Boyer, T. M. Johnson, J. A. Lacey, A. G. Bohorfoush, and M. Mellow, "Elastic scattering spectroscopy as a diagnostic tool for differentiating pathologies in the gastrointestinal tract: preliminary testing," J. Biomed. Opt. 1, 192-199 (1996). (Pubitemid 126649853)
4. G. Zonios, L. T. Perelman, V. Backman, R. Manoharan, M. Fitzmaurice, J.VanDam, and M. S. Feld, "Diffuse reflectance spectroscopy of human adenomatous colon polyps in vivo," Appl. Opt. 38, 6628-6637 (1999). (Pubitemid 129567570)
5. I. J. Bigio, S. G. Bown, G. Briggs, C. Kelley, S. Lakhani, D. Pickard, P. M. Ripley, I. G. Rose, and C. Saunders, "Diagnosis of breast cancer using elastic-scattering spectroscopy: preliminary clinical results," J. Biomed. Opt. 5(2), 221-228 (2000).
6. K. S. Johnson, D. W. Chicken, D. C. Pickard, A. C. Lee, G. Briggs, M. Falzon, I. J. Bigio, M. R. Keshtgar, and S. G. Bown, "Elastic scattering spectroscopy for intraoperative determination of sentinel lymph node status in the breast," J. Biomed. Opt. 9(6), 1122-1128, (2004). (Pubitemid 40168125)
7. L. B. Lovat, K. Johnson, G. D. Mackenzie, B. R. Clark, M. R. Novelli, S. Davies, M. O'Donovan, C. Selvasekar, S. M. Thorpe, D. Pickard, R. Fitzgerald, T. Fearn, I. Bigio, and S. G. Bown, "Elastic scattering spectroscopy accurately detects high grade dysplasia and cancer in Barrett's oesophagus," Gut 55(8), 1078-1083 (2006). (Pubitemid 44085671)
8. D. K. Rex, C. Kahi, M. O'Brien, T. R. Levin, H. Pohl, A. Rastogi, L. Burgart, T. Imperiale, U. Ladabaum, J. Cohen, and D. A. Lieberman, "The American Society for Gastrointestinal Endoscopy PIVI (Preservation and Incorporation of Valuable Endoscopic Innovations) on realtime endoscopic assessment of the histology of diminutive colorectal polyps," Gastrointest. Endosc. 73(3), 419-422 (2011).
9. M. Aksela and J. Laaksonen, "Using diversity of errors for selecting members of a committee classifier," Pattern Recogn. 39(4), 608-623 (2006). (Pubitemid 43199459)
10. R. P. Duin and M. Skurichina, "Combining feature subsets in feature selection," in Multiple Classifier Systems, pp. 165-175, Springer, Berlin (2005).
11. L. Kuncheva, Combining Pattern Classifiers: Methods and Algorithms, Wiley, Hoboken, NJ (2004).
12. K. Tumer, N. Ramanujam, J. Ghosh, and R. Richards-Kortum, "Ensembles of radial basis function networks for spectroscopic detection of cervical precancer," IEEE Trans. Biomed. Eng. 45(8), 953-961 (1998). (Pubitemid 28354470)
13. R. O. Duda, P. E. Hart, and D. G. Stork, Pattern Classification, Wiley, Hoboken, NJ (2001).
14. Y. Freund and R. E. Schapire, "A decision-theoretic generalization of online learning and an application to boosting," J. Comput. Syst. Sci. 55(1), 119-139 (1997). (Pubitemid 127433398)
15. R. E. Schapire, "Theoretical views of boosting," in Proc. of Computational Learning Theory: 4th European Conf., EuroCOLT'99 (1999).
16. S. K. Majumder, N. Ghosh, and P. K.Gupta, "Relevance vectormachine for optical diagnosis of cancer," Lasers Surg. Med. 36(4), 323-333 (2005). (Pubitemid 40578025)
17. N. Ramanujam,M. F.Mitchell, A. Mahadevan, S. Thomsen, A. Malpica, T. Wright, N. Atkinson, and R. Richards-Kortum, "Development of a multivariate statistical algorithm to analyze human cervical tissue fluorescence spectra acquired in vivo," Lasers Surg. Med. 19(1), 46-62 (1996). (Pubitemid 26286498)
18. C. Chow, "On optimum recognition error and reject tradeoff," IEEE Trans. Inf. Theory 16(1), 41-46 (1970).
19. G. Fumera, F. Roli, and G. Giacinto, "Multiple reject thresholds for improving classification reliability," Advances in Pattern Recognition, pp. 863-871, Springer, Berlin, (2000).
20. L. K. Hansen, C. Liisberg, and P. Salamon, "The error-reject tradeoff," Open Syst. Inf. Dyn. 4(2), 159-184 (1997). (Pubitemid 127533737)
21. L. P. Cordella, C. De Stefano, F. Tortorella, and M. Vento, "A method for improving classification reliability of multilayer perceptrons," IEEE Trans. Neural Networks 6(5), 1140-1147 (1995).
22. C. De Stefano, C. Sansone, and M. Vento, "To reject or not to reject: that is the question-an answer in caseof neural classifiers," IEEE Trans. Syst., Man. Cybern., Part C 30(1), 84-94 (2000).
23. A. David and B. Lerner, "Support vector machine-based image classification for genetic syndrome diagnosis," Pattern Recogn. Lett. 26(8), 1029-1038 (2005). (Pubitemid 40556472)
24. S. Mukherjee, P. Tamayo, D. Slonim, A. Verri, T. Golub, J. Mesirov, and T. Poggio, "Support vector machine classification of microarray data," Center for Biological and Computational Learning Paper No. 182/AI Memo No. 1677, Vol. 182, Massachusetts Inst. of Technol., Cambridge, MA (1999).
25. J. Platt, "Probabilistic outputs for support vector machines and comparisons to regularized likelihood methods.," Advances in Large Margin Classifiers, pp. 61-74, MIT Press, Cambridge, MA (1999).
26. F. Tortorella and I. Cassino, "A ROC-Based Reject Rule for Support Vector Machines," Machine Learning and Data Mining in Pattern Recognition, pp. 106-120, Springer, Berlin (2003). (Pubitemid 36904948)
27. C. Yuan and D. Casasent, "A Novel Support Vector Classifier with Better Rejection Performance," in Proc. of IEEE Comput. Soc. Conf. on Computer Vision and Pattern Recognition, Vol. 1, 419-424 (2003).
28. G. Fumera and F. Roli, "Support vector machines with embedded reject option," in SVM '02: Proc. of 1st Int, Workshop on Pattern Recognition with Support Vector Machines, pp. 68-82 (2002).
29. G. Fumera and F. Roli, "Cost-sensitive learning in support vector machines," VIII Convegno Associazione Italiana per L'Intelligenza Artificiale (2002).
30. E. Rodriguez-Diaz and D. A. Castanon, "Support vector machine classifiers for sequential decision problems," in Proc. of 48th IEEE Conf. on Decision and Control, pp. 2558-2563 (2009).
31. Y. Zhu, T. Fearn, D. Samuel, A. Dhar,O.Hameed, S.G. Bown, and L. B. Lovat, "Error removal by orthogonal subtraction (EROS): a customised pre-treatment for spectroscopic data," J. Chemomet. 22(2), 130-134 (2008).
32. Y. Zhu, T. Fearn, G. Mackenzie, B. Clark, J. M. Dunn, I. J. Bigio, S. G. Bown, and L. B. Lovat, "Elastic scattering spectroscopy for detection of cancer risk in Barrett's esophagus: experimental and clinical validation of error removal by orthogonal subtraction for increasing accuracy," J. Biomed. Opt. 14(4), 044022 (2009).
33. A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu, T. Murray, and M. J. Thun, "Cancer statistics, 2008," CA: Cancer J. Clinicians 58(2), 71-96 (2008).
34. R. A. Smith, V. Cokkinides, and O. W. Brawley, "Cancer screening in the United States, 2009: a review of current American Cancer Society guidelines and issues in cancer screening," CA: Cancer J. Clinicians 59(1), 27-41 (2009).
35. D. K. Rex, J. L. Petrini, T. H. Baron, A. Chak, J. Cohen, S. E. Deal, B. Hoffman, B. C. Jacobson, K. Mergener, B. T. Petersen, M. A. Safdi, D. O. Faigel, and I. M. Pike, "Quality indicators for colonoscopy," Gastrointest. Endosc. 63(4 Suppl), S16-28, (2006).
36. G. Postic, D. Lewin, C. Bickerstaff, and M. B. Wallace, "Colonoscopic miss rates determined by direct comparison of colonoscopy with colon resection specimens," Am. J. Gastroenterol. 97(12), 3182-3185 (2002). (Pubitemid 35424594)
37. D. K. Rex, C. S. Cutler, G. T. Lemmel, E. Y. Rahmani, D. W. Clark, D. J. Helper, G. A. Lehman, and D. G. Mark, "Colonoscopic miss rates of adenomas determined by back-to-back colonoscopies," Gastroenterology 112(1), 24-28 (1997). (Pubitemid 27008981)
38. J. R. Mourant, I. J. Bigio, J. Boyer, R. L. Conn, T. Johnson, and T. Shimada, "Spectroscopic diagnosis of bladder cancer with elastic light scattering," Lasers Surg. Med. 17(4), 350-357 (1995).
39. I. J. Bigio, S. G. Bown,C.Kelley, L. Lovat, D. Pickard, and P.M.Ripley, "Developments in endoscopic technology for oesophageal cancer," J. R. Coll. Surg. Edinburgh 45(4), 267-268 (2000).
40. L. Lovat and S. Bown, "Elastic scattering spectroscopy for detection of dysplasia in Barrett's esophagus," Gastrointest. Endosc. Clin. N Am. 14(3), 507-517, ix (2004). (Pubitemid 38903215)
41. L. B. Lovat, K. Johnson, M. R. Novelli, M. O'Donovan, S. Davies, C. R. Selvasekar, S. Thorpe, I. J. Bigio, and S. G. Bown, "Optical biopsy using elastic scattering spectroscopy can detect high grade dysplasia and cancer in Barrett's esophagus," Gastroenterology 126(4), A22-A39 (2004).
42. J. M. Dunn, Y. Jiao,M. Austwick, C. A. Mosse, D. Oukrif, S. Thorpe, M. Novelli, M. R. Banks, S.G. Bown, and L. Lovat, "Elastic scattering spectroscopy is highly accurate for the detection of high grade dysplasia and DNA ploidy arising in Barrett's esophagus using a red enhanced spectrometer," Gastroenterology 138(5), S-664 (2010).
43. J. P. Baak, F. J. ten Kate, G. J. Offerhaus, J. J. van Lanschot, and G. A. Meijer, "Routine morphometrical analysis can improve reproducibility of dysplasia grade in Barrett's oesophagus surveillance biopsies," J. Clin. Pathol. 55(12), 910-916 (2002). (Pubitemid 35454492)
44. H. Fang, M. Ollero, E. Vitkin, L. M. Kimerer, P. B. Cipolloni, M. M. Zaman, S. D. Freedman, I. J. Bigio, I. Itzkan, E. B. Hanlon, and L. T. Perelman, "Noninvasive sizing of subcellular organelles with light scattering spectroscopy," IEEE J. Sel. Top. Quantum Electron. 9(2), 267-276 (2003).
45. I. Georgakoudi, B. C. Jacobson, J. Van Dam, V. Backman, M. B. Wallace, M. G. Müller, Q. Zhang, K. Badizadegan, D. Sun, G. A. Thomas, L. T. Perelman, and M. S. Feld, "Fluorescence, reflectance, and light-scattering spectroscopy for evaluating dysplasia in patients with Barrett's esophagus," Gastroenterology 120(7), 1620-1629 (2001). (Pubitemid 32523481)
46. M. B. Wallace, L. T. Perelman, V. Backman, J. M. Crawford, M. Fizmaurice, M. Seiler, K. Badizadegan, I. Itzkan, R. R. Dasari, J. Van Dam, and M. S. Feld, "Endoscopic detection of dysplasia in patients with Barrett's esophagus using light-scattering spectroscopy," Gastroenterology 119(3), 677-682 (2000).
47. E. Rodriguez-Diaz, I. J. Bigio, and S. K. Singh, "Integrated Optical Tools For Minimally Invasive Diagnosis and Treatment at Gastrointestinal Endoscopy," Robot. Comput. Integr. Manuf. 27(2), 249-256 (2011).
48. G. H. Golub, and C. F. V. Loan, Matrix Computations, 3rd ed., p. 694, Johns Hopkins University Press, Baltimore (1996).
49. C. J. C. Burges, "A tutorial on support vector machines for pattern recognition," Data Mining Knowl. Discov. 2(2), 121-167, (1998). (Pubitemid 128695475)
50. C. Cortes and V. Vapnik, "Support-vector networks," Mach. Learning 20(3), 273-297 (1995).
51. V. N. Vapnik, Statistical Learning Theory,Wiley, Hoboken, NJ (1998).
52. S. K. Chang, Y. N. Mirabal, E. N. Atkinson, D. Cox, A. Malpica, M. Follen, and R. Richards-Kortum, "Combined reflectance and fluorescence spectroscopy for in vivo detection of cervical pre-cancer," J. Biomed. Opt. 10(2), 024031 (2005).
53. D. C. de Veld, M. Skurichina, M. J. Witjes, R. P. Duin, H. J. Sterenborg, and J. L. Roodenburg, "Autofluorescence and diffuse reflectance spectroscopy for oral oncology," Lasers Surg. Med. 36(5), 356-364 (2005). (Pubitemid 40942149)
54. W. Lin, X. Yuan, P. Yuen, W. I. Wei, J. Sham, P. Shi, and J. Qu, "Classification of in vivo autofluorescence spectra using support vector machines," J. Biomed. Opt. 9(1), 180-186, (2004).
55. S. K. Majumder, N. Ghosh, and P. K. Gupta, "Support vector machine for optical diagnosis of cancer," J. Biomed. Opt. 10(2), 024034 (2005).
56. G. M. Palmer, C. Zhu, T. M. Breslin, F. Xu, K. W. Gilchrist, and N. Ramanujam, "Comparison of multiexcitation fluorescence and diffuse reflectance spectroscopy for the diagnosis of breast cancer (March 2003)," IEEE Trans. Biomed. Eng. 50(11), 1233-1242 (2003). (Pubitemid 37339398)
57. N. Ramanujam, M. F. Mitchell, A. Mahadevan-Jansen, S. L. Thomsen, G. Staerkel, A. Malpica, T. Wright, N. Atkinson, and R. Richards- Kortum, "Cervical precancer detection using a multivariate statistical algorithm based on laser-induced fluorescence spectra at multiple excitation wavelengths," Photochem. Photobiol. 64(4), 720-735 (1996). (Pubitemid 27004992)
58. K. Fukunaga, Introduction to Statistical Pattern Recognition, Academic Press, New York (1990).
59. C. Lee and D. A. Landgrebe, "Analyzing high-dimensional multispectral data," IEEE Trans. Geosci. Remote Sens. 31(4), 792-800 (1993).
60. A. Ignjatovic, J. E. East, N. Suzuki, M. Vance, T. Guenther, and B. P. Saunders, "Optical diagnosis of small colorectal polyps at routine colonoscopy (Detect InSpect ChAracterise Resect and Discard; DISCARD trial): a prospective cohort study," Lancet Oncol. 10(12), 1171-1178 (2009).
61. R. Reif, O. A'Amar, and I. J. Bigio, "Analytical model of light reflectance for extraction of the optical properties in small volumes of turbid media," Appl. Opt. 46(29), 7317-7328 (2007).