Anti-tumor activity of curcumin against androgen-independent prostate cancer cells via inhibition of NF-κB and AP-1 pathway in vitro

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 31, Issue 4, 2011, Pages 530-534

  Liu, Shuanglin ^a,b   Wang, Zhihua ^a   Hu, Zhiquan ^a   Zeng, Xing ^a   Li, Youyuan ^a   Su, Yaowu ^c   Zhang, Chuanhua ^b   Ye, Zhangqun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Wuhan First Hospital   (China)

^c Beilun People's Hospital   (China)

Author keywords

Androgen independent prostate cancer; AP 1; Curcumin; NF B

Indexed keywords

ANDROGEN; ANTINEOPLASTIC AGENT; CURCUMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR AP 1;

ARTICLE; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; MALE; METABOLISM; PROSTATE TUMOR; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANDROGENS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CURCUMIN; HUMANS; MALE; NF-KAPPA B; PROSTATIC NEOPLASMS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 80455155235     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-011-0485-1     Document Type: Article

References (22)

1. Crawford ED. Epidemiology of prostate cancer. Urology, 2003,62(6):3-12 (Pubitemid 38050194)
2. Dai B, Ye DW, Kong YY, et al. Individualized prostate biopsy strategy for Chinese patients with different prostate- specific antigen levels. Asian J Androl, 2008,10(2): 325-331 (Pubitemid 351337998)
3. Schutz FA, Oh WK. Neoadjuvant and adjuvant therapies in prostate cancer. Urol Clin North Am, 2010,37(1): 97-104
4. Dorai T, Cao YC, Dorai B, et al. Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo. Prostate, 2001,47(4):293-303 (Pubitemid 32521749)
5. Zeigler CM, Rennert H, Mittal RD, et al. Evaluation of prostate cancer characteristics in four populations worldwide. Can J Urol, 2008,15(3):4056-4064
6. Thangapazham RL, Sharma A, Maheshwari RK. Multiple molecular targets in cancer chemoprevention by curcumin. AAPS J, 2006,8(3):443-449
7. Stacewicz-Sapuntzakis M, Borthakur G, Burns JL, et al. Correlations of dietary patterns with prostate health. Mol Nutr Food Res, 2008,52(1):114-130 (Pubitemid 351216992)
8. Perabo FG, Von Löw EC, Ellinger J, et al. Soy isoflavone genistein in prevention and treatment of prostate cancer. Prostate Cancer Prostatic Dis, 2008,11(1):6-12 (Pubitemid 351250324)
9. Trump DL, Deeb KK, Johnson CS. Vitamin D: considerations in the continued development as an agent for cancer prevention and therapy. Cancer J, 2010,16(1):1-9
10. Oh WK, Small EJ. Complementary and alternative therapies in prostate cancer. Semin Oncol, 2002,29(6):575-584 (Pubitemid 36134980)
11. Aggarwal BB. Prostate cancer and curcumin: add spice to your life. Cancer Biol Ther, 2008,7:1436-1440
12. Chendil D, Ranga RS, Meigooni D, et al. Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3. Oncogene, 2004,23(8):1599-1607 (Pubitemid 38406523)
13. Cui SX, Qu XJ, Xie YY, et al. Curcumin inhibits telomerase activity in human cancer cell lines. Int J Mol Med, 2006,18(2):227-231
14. Kunnumakkara AB, Anand P, Aggarwal BB. Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cancer Lett, 2008,269(2):199-225
15. Claudio E, Saret S, Wang H, et al. Cell-autonomous role for NF-kappa B in immature bone marrow B cells. J Immunol, 2009,182(6):3406-3413
16. Crispen PL, Uzzo RG, Golovine K, et al. Vitamin E succinate inhibits NF-κB and prevents the development of a metastatic phenotype in prostate cancer cells: implications for chemoprevention. Prostate, 2007,67(6):582-590 (Pubitemid 46685277)
17. Suh J, Rabson AB. NF-kappa B activation in human prostate cancer: important mediator or epiphenomenon? J Cell Biochem, 2004,91(1):100-117
18. Zhang L, Altuwaijri S, Deng F, et al. NF-kappaB regulates androgen receptor expression and prostate cancer growth. Am J Pathol, 2009,175(2):489-499
19. Matthews CP, Colburn NH, Young MR. AP-1 a target for cancer prevention. Curr Cancer Drug Targets, 2007,7(4): 317-324 (Pubitemid 46849236)
20. Mukhopadhyay A, Bueso-Ramos C, Chatterjee D, et al. Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines. Oncogene, 2001,20(52): 7597-7609 (Pubitemid 33111860)
21. Jacobs-Helber SM, Wickrema A, Birrer MJ, et al. AP1 regulation of proliferation and initiation of apoptosis in erythropoietin-dependent erythroid cells. Mol Cell Biol, 1998,18(7):3699-3707 (Pubitemid 28287891)
22. Ripple MO, Henry WF, Schwarze SR, et al. Effect of antioxidants on androgen-induced AP-1 and NF-kappaB DNA-binding activity in prostate carcinoma cells. J Natl Cancer Inst, 1999,91(14):1227-1232. (Pubitemid 29357189)