메뉴 건너뛰기




Volumn 7, Issue 11, 2011, Pages 1347-1357

Nanoscale delivery systems for multiple drug combinations in cancer

Author keywords

combination therapy; delivery systems; multiple drugs; nanotechnology; tumor

Indexed keywords

AMINOGLUTETHIMIDE; BEVACIZUMAB; CAMPTOTHECIN; CISPLATIN; COMBRETASTATIN A4; CPX 351; CYTARABINE; DAUNORUBICIN; DOXORUBICIN; FLOXURIDINE; FLUOROURACIL; GEMCITABINE; GONADORELIN; INTERLEUKIN 12; IRINOTECAN; MACROGOL; MITOMYCIN C; N (2 HYDROXYPROPYL)METHACRYLAMIDE; PACLITAXEL; UNCLASSIFIED DRUG; VINCRISTINE; WORTMANNIN;

EID: 80455126018     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon.11.109     Document Type: Review
Times cited : (13)

References (68)
  • 1
    • 1642362625 scopus 로고    scopus 로고
    • Drug delivery systems: Entering the mainstream
    • DOI 10.1126/science.1095833
    • Allen TM, Cullis PR. Drug delivery systems: entering the mainstream. Science 303(5665), 1818-1822 (2004). (Pubitemid 38374867)
    • (2004) Science , vol.303 , Issue.5665 , pp. 1818-1822
    • Allen, T.M.1    Cullis, P.R.2
  • 2
    • 51049090204 scopus 로고    scopus 로고
    • Nanoparticle therapeutics an emerging treatment modality for cancer
    • Davis ME, Chen Z, Shin DM. Nanoparticle therapeutics. an emerging treatment modality for cancer. Nat. Rev. Drug Discov. 7(9), 771-782 (2008).
    • (2008) Nat. Rev. Drug Discov. , vol.7 , Issue.9 , pp. 771-782
    • Davis, M.E.1    Chen, Z.2    Shin, D.M.3
  • 4
    • 68549132581 scopus 로고    scopus 로고
    • PEGylated PLGA nanoparticles for the improved delivery of doxorubicin
    • Park J, Fong PM, Lu J et al. PEGylated PLGA nanoparticles for the improved delivery of doxorubicin. Nanomedicine 5(4), 410-418 (2009).
    • (2009) Nanomedicine , vol.5 , Issue.4 , pp. 410-418
    • Park, J.1    Fong, P.M.2    Lu, J.3
  • 5
    • 77956647113 scopus 로고    scopus 로고
    • Targeted nanodelivery of drugs and diagnostics
    • Phillips MA, Gran ML, Peppas NA. Targeted nanodelivery of drugs and diagnostics. Nano Today 5(2), 143-159 (2010).
    • (2010) Nano Today , vol.5 , Issue.2 , pp. 143-159
    • Phillips, M.A.1    Gran, M.L.2    Peppas, N.A.3
  • 7
    • 79251529926 scopus 로고    scopus 로고
    • Drug delivery systems for differential release in combination therapy
    • Zhang H, Wang G, Yang H. Drug delivery systems for differential release in combination therapy. Expert Opin Drug Deliv. 8(2), 171-190 (2011).
    • (2011) Expert Opin Drug Deliv. , vol.8 , Issue.2 , pp. 171-190
    • Zhang, H.1    Wang, G.2    Yang, H.3
  • 8
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 144(5), 646-674 (2011).
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 9
    • 70349978292 scopus 로고    scopus 로고
    • Combination therapy opportunities and challenges for polymer-drug conjugates as anticancer nanomedicines
    • Greco F, Vicent MJ. Combination therapy. Opportunities and challenges for polymer-drug conjugates as anticancer nanomedicines. Adv. Drug Deliver. Rev. 61(13), 1203-1213 (2009).
    • (2009) Adv. Drug Deliver. Rev. , vol.61 , Issue.13 , pp. 1203-1213
    • Greco, F.1    Vicent, M.J.2
  • 10
    • 77956651717 scopus 로고    scopus 로고
    • Polymeric nanomedicines for image-guided drug delivery and tumor-targeted combination therapy
    • Lammers T, Subr V, Ulbrich K et al. Polymeric nanomedicines for image-guided drug delivery and tumor-targeted combination therapy. Nano Today 5(3), 197-212 (2010).
    • (2010) Nano Today , vol.5 , Issue.3 , pp. 197-212
    • Lammers, T.1    Subr, V.2    Ulbrich, K.3
  • 11
    • 77954277190 scopus 로고    scopus 로고
    • Economic evaluation of zoledronic acid for the prevention of fractures in postmenopausal women with early-stage breast cancer receiving aromatase inhibitors in the United Kingdom
    • Logman JF, Heeg BM, Botteman MF, Kaura S, van Hout BA. Economic evaluation of zoledronic acid for the prevention of fractures in postmenopausal women with early-stage breast cancer receiving aromatase inhibitors in the United Kingdom. Ann. Oncol. 21(7), 1529-1536 (2010).
    • (2010) Ann. Oncol. , vol.21 , Issue.7 , pp. 1529-1536
    • Logman, J.F.1    Heeg, B.M.2    Botteman, M.F.3    Kaura, S.4    Van Hout, B.A.5
  • 12
    • 78049452610 scopus 로고    scopus 로고
    • Delivering nanomedicine to solid tumors
    • Jain RK, Stylianopoulos T. Delivering nanomedicine to solid tumors. Nat. Rev. Clin. Oncol. 7(11), 653-664 (2010).
    • (2010) Nat. Rev. Clin. Oncol. , vol.7 , Issue.11 , pp. 653-664
    • Jain, R.K.1    Stylianopoulos, T.2
  • 13
    • 0035816204 scopus 로고    scopus 로고
    • Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS
    • DOI 10.1016/S0168-3659(01)00309-1, PII S0168365901003091
    • Maeda H, Sawa T, Konno T. Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS. J. Control. Release 74, 47-61 (2001). (Pubitemid 32727608)
    • (2001) Journal of Controlled Release , vol.74 , Issue.1-3 , pp. 47-61
    • Maeda, H.1    Sawa, T.2    Konno, T.3
  • 14
    • 68949104351 scopus 로고    scopus 로고
    • Multiscale measurements distinguish cellular and interstitial hindrances to diffusion in vivo
    • Chauhan VP, Lanning RM, Diop Frimpong B et al. Multiscale measurements distinguish cellular and interstitial hindrances to diffusion in vivo. Biophys. J. 97(1), 330-336 (2009).
    • (2009) Biophys. J. , vol.97 , Issue.1 , pp. 330-336
    • Chauhan, V.P.1    Lanning, R.M.2    Diop Frimpong, B.3
  • 15
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • DOI 10.1126/science.1104819
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307(5706), 58-62 (2005). (Pubitemid 40093472)
    • (2005) Science , vol.307 , Issue.5706 , pp. 58-62
    • Jain, R.K.1
  • 16
    • 79951953022 scopus 로고    scopus 로고
    • Materializing sequential killing of tumor vasculature and tumor cells via targeted polymeric micelle system
    • Wang Y, Yang T, Wang X et al. Materializing sequential killing of tumor vasculature and tumor cells via targeted polymeric micelle system. J. Control. Release 149(3), 299-306 (2011).
    • (2011) J. Control. Release , vol.149 , Issue.3 , pp. 299-306
    • Wang, Y.1    Yang, T.2    Wang, X.3
  • 17
    • 77954384048 scopus 로고    scopus 로고
    • A nanocapsular combinatorial sequential drug delivery system for antiangiogenesis and anticancer activities
    • Wang Z, Ho PC. A nanocapsular combinatorial sequential drug delivery system for antiangiogenesis and anticancer activities. Biomaterials 31(27), 7115-7123 (2010).
    • (2010) Biomaterials , vol.31 , Issue.27 , pp. 7115-7123
    • Wang, Z.1    Ho, P.C.2
  • 18
    • 23144456813 scopus 로고    scopus 로고
    • Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system
    • DOI 10.1038/nature03794
    • Sengupta S, Eavarone D, Capila I et al. Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system. Nature 436(7050), 568-572 (2005). (Pubitemid 41112931)
    • (2005) Nature , vol.436 , Issue.7050 , pp. 568-572
    • Sengupta, S.1    Eavarone, D.2    Capila, I.3    Zhao, G.4    Watson, N.5    Kiziltepe, T.6    Sasisekharan, R.7
  • 20
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Nature Rev. 2(1), 48-58 (2002). (Pubitemid 37328807)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.1 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 21
    • 34250219965 scopus 로고    scopus 로고
    • Chemotherapy-induced resistance by ATP-binding cassette transporter genes
    • DOI 10.1016/j.bbcan.2007.05.002, PII S0304419X07000054
    • Gillet JP, Efferth T, Remacle J. Chemotherapy-induced resistance by ATP-binding cassette transporter genes. Biochim. Biophys. Acta 1775(2), 237-262 (2007). (Pubitemid 46899341)
    • (2007) Biochimica et Biophysica Acta - Reviews on Cancer , vol.1775 , Issue.2 , pp. 237-262
    • Gillet, J.-P.1    Efferth, T.2    Remacle, J.3
  • 22
    • 19644369801 scopus 로고    scopus 로고
    • In vitro cytotoxicity of stealth liposomes co-encapsulating doxorubicin and verapamil on doxorubicin-resistant tumor cells
    • Wang JC, Goh BC, Lu WL et al. In vitro cytotoxicity of Stealth liposomes co-encapsulating doxorubicin and verapamil on doxorubicin-resistant tumor cells. Biol. Pharm. Bull. 28, 822-828 (2005).
    • (2005) Biol. Pharm. Bull. , vol.28 , pp. 822-828
    • Wang, J.C.1    Goh, B.C.2    Lu, W.L.3
  • 24
    • 67349243616 scopus 로고    scopus 로고
    • Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance
    • Patil Y, Sadhukha T, Ma L, Panyam J. Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance. J. Control. Release 136, 21-29 (2009).
    • (2009) J. Control. Release , vol.136 , pp. 21-29
    • Patil, Y.1    Sadhukha, T.2    Ma, L.3    Panyam, J.4
  • 25
    • 38549178381 scopus 로고    scopus 로고
    • PLGA nanoparticles simultaneously loaded with vincristine sulfate and verapamil hydrochloride: Systematic study of particle size and drug entrapment efficiency
    • DOI 10.1016/j.ijpharm.2007.08.034, PII S0378517307007314
    • Song XR, Zhao Y, Wu WB et al. PLGA nanoparticles simultaneously loaded with vincristine sulfate and verapamil hydrochloride. Systematic study of particle size and drug entrapment efficiency. Int. J. Pharm. 350, 320-329 (2008). (Pubitemid 351146679)
    • (2008) International Journal of Pharmaceutics , vol.350 , Issue.1-2 , pp. 320-329
    • Song, X.1    Zhao, Y.2    Wu, W.3    Bi, Y.4    Cai, Z.5    Chen, Q.6    Li, Y.7    Hou, S.8
  • 26
    • 43249096164 scopus 로고    scopus 로고
    • Dual agents loaded PLGA nanoparticles: Systematic study of particle size and drug entrapment efficiency
    • Song X, Zhao Y, Hou S et al. Dual agents loaded PLGA nanoparticles: systematic study of particle size and drug entrapment efficiency. Eur. J. Pharm. Biopharm. 69, 445-453 (2008).
    • (2008) Eur. J. Pharm. Biopharm. , vol.69 , pp. 445-453
    • Song, X.1    Zhao, Y.2    Hou, S.3
  • 27
    • 67349283551 scopus 로고    scopus 로고
    • Reversion of multidrug resistance by co-encapsulation of vincristine and verapamil in PLGA nanoparticles
    • Song XR, Cai Z, Zheng Y et al. Reversion of multidrug resistance by co-encapsulation of vincristine and verapamil in PLGA nanoparticles. Eur. J. Pharm. Sci. 37, 300-305 (2009).
    • (2009) Eur. J. Pharm. Sci. , vol.37 , pp. 300-305
    • Song, X.R.1    Cai, Z.2    Zheng, Y.3
  • 28
    • 57449093837 scopus 로고    scopus 로고
    • Effect of adjuvant paclitaxel and carboplatin for advanced stage epithelial ovarian cancer: A population-based cohort study of all patients in western Sweden with long-term follow-up
    • Akeson M, Zetterqvist BM, Dahllöf K, Brännström M, Horvath G. Effect of adjuvant paclitaxel and carboplatin for advanced stage epithelial ovarian cancer: a population-based cohort study of all patients in western Sweden with long-term follow-up. Acta Obstet. Gynecol. Scand. 87(12) 1343-1352 (2008).
    • (2008) Acta Obstet. Gynecol. Scand. , vol.87 , Issue.12 , pp. 1343-1352
    • Akeson, M.1    Zetterqvist, B.M.2    Dahllöf, K.3    Brännström, M.4    Horvath, G.5
  • 29
    • 77953650323 scopus 로고    scopus 로고
    • Toward delivery of multiple growth factors in tissue engineering
    • Chen FM, Zhang M, Wu ZF. Toward delivery of multiple growth factors in tissue engineering. Biomaterials 31(24), 6279-6308 (2010).
    • (2010) Biomaterials , vol.31 , Issue.24 , pp. 6279-6308
    • Chen, F.M.1    Zhang, M.2    Wu, Z.F.3
  • 30
    • 67349283045 scopus 로고    scopus 로고
    • Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers
    • Lammers T, Subr V, Ulbrich K et al. Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers. Biomaterials 30(20), 3466-3475 (2009).
    • (2009) Biomaterials , vol.30 , Issue.20 , pp. 3466-3475
    • Lammers, T.1    Subr, V.2    Ulbrich, K.3
  • 31
    • 34548607549 scopus 로고    scopus 로고
    • Mixed polymeric micelles for combination cancer chemotherapy through the concurrent delivery of multiple chemotherapeutic agents
    • DOI 10.1016/j.jconrel.2007.05.038, PII S0168365907002817, Proceedings of the Thirtheenth International Symposium on Recent Advances in Drug Delivery Systems
    • Bae Y, Diezi TA, Zhao A, Kwon GS. Mixed polymeric micelles for combination cancer chemotherapy through the concurrent delivery of multiple chemotherapeutic agents. J. Control. Release 122(3), 324-330 (2007). (Pubitemid 47404677)
    • (2007) Journal of Controlled Release , vol.122 , Issue.3 , pp. 324-330
    • Bae, Y.1    Diezi, T.A.2    Zhao, A.3    Kwon, G.S.4
  • 32
    • 77649185057 scopus 로고    scopus 로고
    • Targeted delivery of RGD-modified liposomes encapsulating both combretastatin A 4 and doxorubicin for tumor therapy in vitro and in vivo studies
    • Zhang YF, Wang JC, Bian DY, Zhang X, Zhang Q. Targeted delivery of RGD-modified liposomes encapsulating both combretastatin A 4 and doxorubicin for tumor therapy. in vitro and in vivo studies. Eur. J. Pharm. Biopharm. 74, 467-473 (2010).
    • (2010) Eur. J. Pharm. Biopharm. , vol.74 , pp. 467-473
    • Zhang, Y.F.1    Wang, J.C.2    Bian, D.Y.3    Zhang, X.4    Zhang, Q.5
  • 35
    • 33846549188 scopus 로고    scopus 로고
    • Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells
    • DOI 10.1016/j.jconrel.2006.10.012, PII S0168365906005542
    • Greco F, Vicent MJ, Gee S et al. Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-DOX-AGM in breast cancer cells. J. Control. Release 117(1), 28-39 (2007). (Pubitemid 46164864)
    • (2007) Journal of Controlled Release , vol.117 , Issue.1 , pp. 28-39
    • Greco, F.1    Vicent, M.J.2    Gee, S.3    Jones, A.T.4    Gee, J.5    Nicholson, R.I.6    Duncan, R.7
  • 36
    • 70349784954 scopus 로고    scopus 로고
    • Targeting bone metastases with a bispecific anticancer and antiangiogenic polymer-alendronate-taxane conjugate
    • Miller K, Erez R, Segal E, Shabat D, Satchi-Fainaro R. Targeting bone metastases with a bispecific anticancer and antiangiogenic polymer-alendronate- taxane conjugate. Angew. Chem. Int. Ed. Engl. 48, 2949-2954 (2009).
    • (2009) Angew. Chem. Int. Ed. Engl. , vol.48 , pp. 2949-2954
    • Miller, K.1    Erez, R.2    Segal, E.3    Shabat, D.4    Satchi-Fainaro, R.5
  • 37
    • 67349247858 scopus 로고    scopus 로고
    • HPMA-based polymer conjugates with drug combination
    • Krakovicova H, Etrych T, Ulbrich K. HPMA-based polymer conjugates with drug combination. Eur. J. Pharm. Sci. 37, 405-412 (2009).
    • (2009) Eur. J. Pharm. Sci. , vol.37 , pp. 405-412
    • Krakovicova, H.1    Etrych, T.2    Ulbrich, K.3
  • 38
    • 67249148559 scopus 로고    scopus 로고
    • A combined chemoimmunotherapy approach using a plasmid-doxorubicin complex
    • Bagalkot V, Lee IH, Yu MK et al. A combined chemoimmunotherapy approach using a plasmid-doxorubicin complex. Mol. Pharm. 6, 1019-1028 (2009).
    • (2009) Mol. Pharm. , vol.6 , pp. 1019-1028
    • Bagalkot, V.1    Lee, I.H.2    Yu, M.K.3
  • 40
    • 55849099605 scopus 로고    scopus 로고
    • Active targeting schemes for nanoparticle systems in cancer therapeutics
    • Byrne JD, Betancourt T, Brannon-Peppas L. Active targeting schemes for nanoparticle systems in cancer therapeutics. Adv. Drug Deliv. Rev. 60(15), 1615-1626 (2008).
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , Issue.15 , pp. 1615-1626
    • Byrne, J.D.1    Betancourt, T.2    Brannon-Peppas, L.3
  • 41
    • 79952315769 scopus 로고    scopus 로고
    • Why and how to prepare biodegradable monodispersed polymeric microparticles in the field of pharmacy
    • Tran VT, Benoit JP, Venier-Julienne MC. Why and how to prepare biodegradable, monodispersed, polymeric microparticles in the field of pharmacy? Int. J. Pharm. 407, 1-11 (2011).
    • (2011) Int. J. Pharm. , vol.407 , pp. 1-11
    • Tran, V.T.1    Benoit, J.P.2    Venier-Julienne, M.C.3
  • 42
    • 70449711530 scopus 로고    scopus 로고
    • Multi-drug loaded polymeric micelles for simultaneous delivery of poorly soluble anticancer drugs
    • Shin HC, Alani AWG, Rao DA, Rockich NC, Kwon GS. Multi-drug loaded polymeric micelles for simultaneous delivery of poorly soluble anticancer drugs. J. Control. Release 140, 294-300 (2009).
    • (2009) J. Control. Release , vol.140 , pp. 294-300
    • Shin, H.C.1    Alani, A.W.G.2    Rao, D.A.3    Rockich, N.C.4    Kwon, G.S.5
  • 43
    • 37349059289 scopus 로고    scopus 로고
    • The effects of irradiation on controlled drug delivery/controlled drug release systems
    • DOI 10.1016/j.radphyschem.2007.06.006, PII S0969806X07002824
    • Razem D, Katusin-Razem B. The effects of irradiation on controlled drug delivery/controlled drug release systems. Radiat. Phys. Chem. 77(3), 288-344 (2008). (Pubitemid 350297979)
    • (2008) Radiation Physics and Chemistry , vol.77 , Issue.3 , pp. 288-344
    • Razem, D.1    Katusin-Razem, B.2
  • 44
    • 33749983751 scopus 로고    scopus 로고
    • Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer
    • DOI 10.1038/nmat1737, PII NMAT1737
    • Wang Y, Gao S, Ye WH, Yoon HS, Yang YY. Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer. Nat. Mater. 5, 791-796 (2006). (Pubitemid 44570860)
    • (2006) Nature Materials , vol.5 , Issue.10 , pp. 791-796
    • Wang, Y.1    Gao, S.2    Ye, W.-H.3    Yoon, H.S.4    Yang, Y.-Y.5
  • 45
    • 57649124218 scopus 로고    scopus 로고
    • The co-delivery of paclitaxel and Herceptin using cationic micellar nanoparticles
    • Lee A, Wang Y, Cheng H, Pervaiz S, Yang YY. The co-delivery of paclitaxel and Herceptin using cationic micellar nanoparticles. Biomaterials 30, 919-927 (2009).
    • (2009) Biomaterials , vol.30 , pp. 919-927
    • Lee, A.1    Wang, Y.2    Cheng, H.3    Pervaiz, S.4    Yang, Y.Y.5
  • 46
    • 77954302022 scopus 로고    scopus 로고
    • Combinatorial drug conjugation enables nanoparticle dual-drug delivery
    • Aryal S, Hu C-MJ, Zhang L. Combinatorial drug conjugation enables nanoparticle dual-drug delivery. Small 6, 1442-1448 (2010).
    • (2010) Small , vol.6 , pp. 1442-1448
    • Aryal, S.1    Hu, C.-M.J.2    Zhang, L.3
  • 47
    • 0842333135 scopus 로고    scopus 로고
    • In Vitro and in Vivo Characterization of Doxorubicin and Vincristine Coencapsulated within Liposomes through Use of Transition Metal Ion Complexation and pH Gradient Loading
    • DOI 10.1158/1078-0432.CCR-1131-03
    • Abraham SA, McKenzie C, Masin D et al. In vitro and in vivo characterization of doxorubicin and vincristine coencapsulated within liposomes through use of transition metal ion complexation and pH gradient loading. Clin. Cancer Res. 10, 728-738 (2004). (Pubitemid 38174011)
    • (2004) Clinical Cancer Research , vol.10 , Issue.2 , pp. 728-738
    • Abraham, S.A.1    McKenzie, C.2    Masin, D.3    Ng, R.4    Harasym, T.O.5    Mayer, L.D.6    Bally, M.B.7
  • 49
    • 74849110624 scopus 로고    scopus 로고
    • A novel doxorubicin-mitomycin C co-encapsulated nanoparticle formulation exhibits anti-cancer synergy in multidrug resistant human breast cancer cells
    • Shuhendler AJ, Cheung RY, Manias J, Connor A, Rauth AM, Wu XY. A novel doxorubicin-mitomycin C co-encapsulated nanoparticle formulation exhibits anti-cancer synergy in multidrug resistant human breast cancer cells. Breast Cancer Res. Treat. 119, 255-269 (2009).
    • (2009) Breast Cancer Res. Treat. , vol.119 , pp. 255-269
    • Shuhendler, A.J.1    Cheung, R.Y.2    Manias, J.3    Connor, A.4    Rauth, A.M.5    Wu, X.Y.6
  • 50
    • 75549087162 scopus 로고    scopus 로고
    • Nanosystem drug targeting: Facing up to complex realities
    • Ruenraroengsak P, Cook JM, Florence AT. Nanosystem drug targeting: facing up to complex realities. J. Control. Release 141(3), 265-276 (2010).
    • (2010) J. Control. Release , vol.141 , Issue.3 , pp. 265-276
    • Ruenraroengsak, P.1    Cook, J.M.2    Florence, A.T.3
  • 51
    • 77955175216 scopus 로고    scopus 로고
    • Strategies in the design of nanoparticles for therapeutic applications
    • Petros RA, DeSimone JM. Strategies in the design of nanoparticles for therapeutic applications. Nat. Rev. Drug Discov. 9(8), 615-627 (2010).
    • (2010) Nat. Rev. Drug Discov. , vol.9 , Issue.8 , pp. 615-627
    • Petros, R.A.1    DeSimone, J.M.2
  • 52
    • 33644840292 scopus 로고    scopus 로고
    • Growth factor-delivery systems for tissue engineering materials perspective
    • Vasita R, Katti DS. Growth factor-delivery systems for tissue engineering. materials perspective. Expert Rev. Med. Devices 3(1), 29-47 (2006).
    • (2006) Expert Rev. Med. Devices , vol.3 , Issue.1 , pp. 29-47
    • Vasita, R.1    Katti, D.S.2
  • 54
    • 65949099436 scopus 로고    scopus 로고
    • Localized delivery of growth factors for periodontal tissue regeneration: Role strategies and perspectives
    • Chen FM, Shelton RM, Jin Y, Chapple IL. Localized delivery of growth factors for periodontal tissue regeneration: role, strategies, and perspectives. Med. Res. Rev. 29(3), 472-513 (2009).
    • (2009) Med. Res. Rev. , vol.29 , Issue.3 , pp. 472-513
    • Chen, F.M.1    Shelton, R.M.2    Jin, Y.3    Chapple, I.L.4
  • 55
    • 57749182923 scopus 로고    scopus 로고
    • Preparation of aspirin and probucol in combination loaded chitosan nanoparticles and in vitro release study
    • Wan A, Sun Y, Gao L, Li H. Preparation of aspirin and probucol in combination loaded chitosan nanoparticles and in vitro release study. Carbohydr. Polym. 75, 566-574 (2009).
    • (2009) Carbohydr. Polym. , vol.75 , pp. 566-574
    • Wan, A.1    Sun, Y.2    Gao, L.3    Li, H.4
  • 56
    • 70350662339 scopus 로고    scopus 로고
    • Promises facts and challenges for carbon nanotubes in imaging and therapeutics
    • Kostarelos K, Bianco A, Prato M. Promises, facts and challenges for carbon nanotubes in imaging and therapeutics. Nat. Nanotechnol. 4(10), 627-633 (2009).
    • (2009) Nat. Nanotechnol. , vol.4 , Issue.10 , pp. 627-633
    • Kostarelos, K.1    Bianco, A.2    Prato, M.3
  • 57
    • 73349141177 scopus 로고    scopus 로고
    • Co-delivery of doxorubicin and Bcl 2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells
    • Chen AM, Zhang M, Wei D et al. Co-delivery of doxorubicin and Bcl 2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells. Small 5, 2673-2677 (2009).
    • (2009) Small , vol.5 , pp. 2673-2677
    • Chen, A.M.1    Zhang, M.2    Wei, D.3
  • 59
    • 75749134040 scopus 로고    scopus 로고
    • Improving the efficacy of combined modality anticancer therapy using HPMA copolymer-based nanomedicine formulations
    • Lammers T. Improving the efficacy of combined modality anticancer therapy using HPMA copolymer-based nanomedicine formulations. Adv. Drug Deliv. Rev. 62(2), 203-230 (2009).
    • (2009) Adv. Drug Deliv. Rev. , vol.62 , Issue.2 , pp. 203-230
    • Lammers, T.1
  • 60
    • 61449184602 scopus 로고    scopus 로고
    • A Phase I and pharmacokinetic study of paclitaxel poliglumex and cisplatin in patients with advanced solid tumors
    • Verschraegen CF, Skubitz K, Daud A et al. A Phase I and pharmacokinetic study of paclitaxel poliglumex and cisplatin in patients with advanced solid tumors. Cancer Chemother. Pharmacol. 63(5), 903-910 (2009).
    • (2009) Cancer Chemother. Pharmacol. , vol.63 , Issue.5 , pp. 903-910
    • Verschraegen, C.F.1    Skubitz, K.2    Daud, A.3
  • 61
    • 79960594827 scopus 로고    scopus 로고
    • Liposomal encapsulation of a synergistic molar ratio of cytarabine and daunorubicin enhances selective toxicity for acute myeloid leukemia progenitors as compared to analogous normal hematopoietic cells
    • Kim HP, Gerhard B, Harasym TO et al. Liposomal encapsulation of a synergistic molar ratio of cytarabine and daunorubicin enhances selective toxicity for acute myeloid leukemia progenitors as compared to analogous normal hematopoietic cells. Exp. Hematol. 39, 741-750 (2011).
    • (2011) Exp. Hematol. , vol.39 , pp. 741-750
    • Kim, H.P.1    Gerhard, B.2    Harasym, T.O.3
  • 62
    • 79952757852 scopus 로고    scopus 로고
    • First-in-man study of CPX-351: A liposomal carrier containing cytarabine and daunorubicin in a fixed 5:1 molar ratio for the treatment of relapsed and refractory acute leukemia
    • Feldman EJ, Lancet JE, Kolitz JE et al. First-in-man study of CPX-351: a liposomal carrier containing cytarabine and daunorubicin in a fixed 5:1 molar ratio for the treatment of relapsed and refractory acute leukemia. J. Clin. Oncol. 29, 979-985 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , pp. 979-985
    • Feldman, E.J.1    Lancet, J.E.2    Kolitz, J.E.3
  • 63
    • 78649947932 scopus 로고    scopus 로고
    • Use of nanoscale delivery systems to maintain synergistic drug ratios in vivo
    • Dicko A, Mayer LD, Tardi PG. Use of nanoscale delivery systems to maintain synergistic drug ratios in vivo. Expert Opin. Drug Deliv. 12(7), 1329-1341 (2010).
    • (2010) Expert Opin. Drug Deliv. , vol.12 , Issue.7 , pp. 1329-1341
    • Dicko, A.1    Mayer, L.D.2    Tardi, P.G.3
  • 64
    • 74249095292 scopus 로고    scopus 로고
    • Lipid-based nanoparticulate systems for the delivery of anti-cancer drug cocktails: Implications on pharmacokinetics and drug toxicities
    • Chiu GNC, Wong MY, Ling LU et al. Lipid-based nanoparticulate systems for the delivery of anti-cancer drug cocktails: implications on pharmacokinetics and drug toxicities. Curr. Drug Metab. 10(8), 861-874(2009).
    • (2009) Curr. Drug Metab. , vol.10 , Issue.8 , pp. 861-874
    • Chiu, G.N.C.1    Wong, M.Y.2    Ling, L.U.3
  • 65
    • 77956281680 scopus 로고    scopus 로고
    • Optimization of vincristine-topotecan combination - Paving the way for improved chemotherapy regimens by nanoliposomes
    • Zucker D, Barenholz Y. Optimization of vincristine-topotecan combination - paving the way for improved chemotherapy regimens by nanoliposomes. J. Control. Release 146(3), 326-333 (2010).
    • (2010) J. Control. Release , vol.146 , Issue.3 , pp. 326-333
    • Zucker, D.1    Barenholz, Y.2
  • 66
    • 67651108720 scopus 로고    scopus 로고
    • Nanoparticulate assemblies of amphiphiles and diagnostically active materials for multimodality imaging
    • Mulder WJM, Strijkers GJ, van Tilborg GA et al. Nanoparticulate assemblies of amphiphiles and diagnostically active materials for multimodality imaging. Acc. Chem. Res. 42 (7), 904-914 (2009).
    • (2009) Acc. Chem. Res. , vol.42 , Issue.7 , pp. 904-914
    • Mulder, W.J.M.1    Strijkers, G.J.2    Van Tilborg, G.A.3
  • 67
    • 33846050010 scopus 로고    scopus 로고
    • Spatio-temporal VEGF and PDGF delivery patterns blood vessel formation and maturation
    • DOI 10.1007/s11095-006-9173-4
    • Chen RR, Silva EA, Yuen WW et al. Spatio-temporal VEGF and PDGF delivery patterns blood vessel formation and maturation. Pharm. Res. 24(2), 258-264 (2007). (Pubitemid 46072185)
    • (2007) Pharmaceutical Research , vol.24 , Issue.2 , pp. 258-264
    • Chen, R.R.1    Silva, E.A.2    Yuen, W.W.3    Mooney, D.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.