A meta-analysis of fluorodeoxyglucose-positron emission tomography versus scintigraphy in the evaluation of suspected osteomyelitis

Nuclear Medicine Communications

Volumn 32, Issue 12, 2011, Pages 1134-1142

  Wang, Guo Lin ^a   Zhao, Kui ^a   Liu, Zhen Feng ^a   Dong, Meng Jie ^a   Yang, Shu Ye ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

diagnostic accuracy; FDG PET; meta analysis; suspected osteomyelitis scintigraphy

Indexed keywords

FLUORODEOXYGLUCOSE; IODINE 123; TECHNETIUM 99M;

ARTICLE; BONE RADIOGRAPHY; BONE SCINTISCANNING; COMPARATIVE STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; HUMAN; LEUKOCYTE SCINTIGRAPHY; META ANALYSIS; MONOCLONAL GRANULOCYTE ANTIBODY SCINTIGRAPHY; OSTEOMYELITIS; POSITRON EMISSION TOMOGRAPHY; SCINTIGRAPHY; SENSITIVITY AND SPECIFICITY; SYSTEMATIC REVIEW;

ANTIBODIES, MONOCLONAL; BONE AND BONES; FLUORODEOXYGLUCOSE F18; HUMANS; LEUKOCYTES; OSTEOMYELITIS; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; RADIONUCLIDE IMAGING; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 80455122934     PISSN: 01433636     EISSN: 14735628     Source Type: Journal    
DOI: 10.1097/MNM.0b013e32834b455c     Document Type: Article

References (45)

1. Concia E, Prandini N, Massari L, Ghisellini F, Consoli V, Menichetti F, Lazzeri E. Osteomyelitis: clinical update for practical guidelines. Nucl Med Commun 2006; 27:645-660.
2. Von Rothenburg T, Schaffstein J, Ludwig J, Vehling D, Kö ster O, Schmid G. Imaging osteomyelitis with Tc-99m-labeled antigranulocyte antibody Fab' fragments. Clin Nucl Med 2003; 28:643-647.
3. Guhlmann A, Brecht-Krauss D, Suger G, Glatting G, Kotzerke J, Kinzl L, Reske SN. Chronic osteomyelitis: detection with FDG PET and correlation with histopathologic findings. Radiology 1998; 206:749-754.
4. Bleeker-Rovers CP, De Kleijn EM, Corstens FH, van der Meer JW, Oyen WJ. Clinical value of FDG PET in patients with fever of unknown origin and patients suspected of focal infection or inflammation. Eur J Nucl Med Mol Imaging 2004; 31:29-37.
5. Kubota R, Yamada S, Kubota K, Ishiwata K, Tamahashi N, Ido T. Intratumoral distribution of fluorine-18-fluorodeoxyglucose in vivo: high accumulation in macrophages and granulation tissues studied by microautoradiography. J Nucl Med 1992; 33:1972-1980.
6. Yamada S, Kubota K, Kubota R, Ido T, Tamahashi N. High accumulation of fluorine-18-fluorodcoxyglucosc in turpentine-induced inflammatory tissue. J Nucl Med 1995; 36:1301-1306.
7. Termaat MF, Raijmakers PG, Scholten HJ, Bakker FC, Patka P, Haarman HJ. The accuracy of diagnostic imaging for the assessment of chronicosteomyelitis: a systematic review and meta-analysis. J Bone Joint Surg Am 2005; 87:2464-2471.
8. Whiting P, Rutjes AW, Reitsma JB, Glas AS, Bossuyt PM, Kleijnen J. The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol 2003; 3:25.
9. Delbeke D, Coleman RE, Guiberteau MJ, Glas AS, Bossuyt PM, Kleijnen J. Procedure guideline for tumor imaging with 18F-FDG PET/CT 1.0. J Nucl Med 2006; 47:885-895.
10. Irwig L, Macaskill P, Glasziou P, Fahey M. Meta-analytic methods for diagnostic test accuracy. J Clin Epidemiol 1995; 48:119-130.
11. Moses LE, Shapiro D, Littenberg B. Combining independent studies of a diagnostic test into a summary ROC curve: data-analytic approaches and some additional considerations. Stat Med 1993; 12:1293-1316.
12. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003; 327:557-560.
13. Zamora J, Abraira V, Muriel A, Khan K, Coomarasamy A. Meta-DiSc: a software for meta-analysis of test accuracy data. BMC Med Res Methodol 2006; 6:31.
14. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315:629-634.
15. Guhlmann A, Brecht-Krauss D, Suger G, Glatting G, Kotzerke J, Kinzl L, Reske SN. Fluorine-18-FDG PET and technetium-99m antigranulocyte antibody scintigraphy in chronic osteomyelitis. J Nucl Med 1998; 39: 2145-2152.
16. Zhuang H, Duarte PS, Pourdehand M, Shnier D, Alavi A. Exclusion of chronic osteomyelitis with F-18 fluorodeoxyglucose positron emission tomographic imaging. Clin Nucl Med 2000; 25:281-284.
17. Kalicke T, Schmitz A, Risse JH, Arens S, Keller E, Hansis M, et al. Fluorine-18 fluorodeoxyglucose PET in infectious bone diseases: results of histologically confirmed cases. Eur J Nucl Med Mol Imaging 2000; 27:524-528.
18. Chacko TK, Zhuang H, Nakhoda KZ, Moussavian B, Alavi A. Applications of fluorodeoxyglucose positron emission tomography in the diagnosis of infection. Nucl Med Commun 2003; 24:615-624.
19. Hartmann A, Eid K, Dora C, Trentz O, von Schulthess GK, Stumpe KD. Diagnostic value of 18F-FDG PET/CT in trauma patients with suspected chronic osteomyelitis. Eur J Nucl Med Mol Imaging 2007; 34:704-714.
20. Nawaz A, Torigian DA, Siegelman ES, Basu S, Chryssikos T, Alavi A. Diagnostic performance of FDG-PET, MRI, and plain film radiography (PFR) for the diagnosis of osteomyelitis in the diabetic foot. Mol Imaging Biol 2010; 12:335-342.
21. Harwood SJ, Valdivia S, Hung GL, Quenzer RW. Use of sulesomab, a radiolabeled antibody fragment, to detect osteomyelitis in diabetic patients with foot ulcers by leukoscintigraphy. Clin Infect Dis 1999; 28:1200-1205.
22. Devillers A, Garin E, Polard JL, Poirier JY, Arvieux C, Girault S, et al. Comparison of Tc-99m-labelled antileukocyte fragment Fab' and Tc-99m- HMPAO leukocyte scintigraphy in the diagnosis of bone and joint infections: a prospective study. Nucl Med Commun 2000; 21:747-753.
23. Kaim A, Ledermann HP, Bongartz G, Steinbrich W. Chronic post-traumatic osteomyelitis of the lower extremity: comparison of magnetic resonance imaging and combined bone scintigraphy/immunoscintigraphy with radiolabelled monoclonal antigranulocyte antibodies. Skeletal Radiol 2000; 29:378-386.
24. Vicente AG, Almoguera M, Alonso JC, Heffernan AJ, Gomez A, Contreras PI, Martin-Comin J. Diagnosis of orthopedic infection in clinical practice using Tc-99m sulesomab (antigranulocyte monoclonal antibody fragment Fab'2). Clin Nucl Med 2004; 29:781-785.
25. Rubello D, Casara D, Maran A, Avogaro A, Tiengo A, Muzzio PC. Role of anti-granulocyte Fab' fragment antibody scintigraphy (LeukoScan) in evaluating bone infection: acquisition protocol, interpretation criteria and clinical results. Nucl Med Commun 2004; 25:39-47.
26. Esterhai JL Jr, Goll SR, McCarthy KE, Velchik M, Alavi A, Brighton CT, Heppenstall RB. Indium-111 leukocyte scintigraphic detection of subclinical osteomyelitis complicating delayed and nonunion long bone fractures: a prospective study. J Orthop Res 1987; 5:1-6.
27. Krznaric E, Roo MD, Verbruggen A, Stuyck J, Mortelmans L. Chronic osteomyelitis: diagnosis with technetium-99m-d,l-hexamethylpropylene amine oxime labeled leucocytes. Eur J Nucl Med 1996; 23:792-797.
28. Hakim SG, Bruecker CW, Jacobsen H, Hermes D, Lauer I, Eckerle S, et al. The value of FDG-PET and bone scintigraphy with SPECT in the primary diagnosis and follow-up of patients with chronic osteomyelitis of the mandible. Int J Oral Maxillofac Surg 2006; 35:809-816.
29. Horger M, Eschmann SM, Pfannenberg C, Vonthein R, Besenfelder H, Claussen CD, Bares R. Added value of SPECT/CT in patients suspected of having bone infection: preliminary results. Arch Orthop Trauma Surg 2007; 127:211-221.
30. Scheidler J, Leinsinger G, Pfahler M, Kirsch CM. Diagnosis of osteomyelitis. Accuracy and limitations of antigranulocyte antibody imaging compared to three-phase bone scan. Clin Nucl Med 1994; 19:731-737.
31. Kaim A, Maurer T, Ochsner P, Jundt G, Mueller-Brand J. Chronic complicated osteomyelitis of the appendicular skeleton: diagnosis with technetium-99m labelled monoclonal antigranulocyte antibodyimmunoscintigraphy. Eur J Nucl Med 1997; 24:732-738.
32. Nijhof MW, Oyen WJ, Van Kampen A, Claessens RA, van der Meer JW, Corstens FH. Evaluation of infections of the locomotor system with indium- 111-labeled human IgG scintigraphy. J Nucl Med 1997; 38:1300-1305.
33. Williamson MR, Quenzer RW, Rosenberg RD, Meholic AJ, Eisenberg B, Espinosa MC, Hartshorne MF. Osteomyelitis: sensitivity of 0.064 T MRI, three-phase bone scanning and indium scanning with biopsy proof. Magn Reson Imaging 1991; 9:945-948.
34. Palestro CJ, Kim CK, Swyer AJ, Vallabhajosula S, Goldsmith SJ. Radionuclide diagnosis of vertebral osteomyelitis: indium-111-leukocyte and technetium-99m-methylene diphosphonate bone scintigraphy. J Nucl Med 1991; 32:1861-1865.
35. Palestro CJ, Kipper SL, Weiland FL, Love C, Tomas MB. Osteomyelitis: diagnosis with (99m)Tc-labeled antigranulocyte antibodies compared with diagnosis with (111)In-labeled leukocytes - initial experience. Radiology 2002; 223:758-764.
36. Van der Bruggen W, Bleeker-Rovers CP, Boerman OC, Gotthardt M, Oyen WJ. PET and SPECT in osteomyelitis and prosthetic bone and joint infections: a systematic review. Semin Nucl Med 2010; 40:3-15.
37. Seybold K, Frey LD, Locher J. Immunoscintigraphy of infections using 123I and 99mTc labeled monoclonal antibodies: advanced experiences in 230 patients. Angiology 1992; 43:85-90.
38. Becker W, Bair J, Behr T, Repp R, Streckenbach H, Beck H, et al. Detection of soft-tissue infections and osteomyelitis using a technetium-99m-labeled anti-granulocyte monoclonal antibody fragment. J Nucl Med 1994; 35:1436-1443.
39. Pakos EE, Koumoulis HD, Fotopoulos AD, Ioannidis JP. Osteomyelitis: antigranulocyte scintigraphy with 99mTc radiolabeled monoclonal antibodies for diagnosis: meta-analysis. Radiology 2007; 245:732-741.
40. Borregaard N, Herlin T. Energy metabolism of human neutrophils during phagocytosis. J Clin Invest 1982; 70:550-557.
41. Sugawara Y, Braun D, Kison P, Russo JE, Zasadny KR, Wahl RL. Rapid detection of human infections with fluorine-18 fluorodeoxyglucose and positron emission tomography: preliminary results. Eur J Nucl Med 1998; 25:1238-1243.
42. Kjaer A, Lebech AM, Eigtved A, Højgaard L. Fever of unknown origin: prospective comparison of diagnostic value of 18F-FDG PET and 111Ingranulocyte scintigraphy. Eur J Nucl Med Mol Imaging 2004; 31: 1342-1343.
43. Schiesser M, Stumpe KD, Trentz O, Kossmann T, Von Schulthess GK. Detection of metallic implant associated infections with FDG PET in patients with trauma: correlation with microbiologic results. Radiology 2003; 226:391-398.
44. De Winter F, Van de Wiele C, Vogelaers D, de Smet K, Verdonk R, Dierckx RA. Fluorine-18 fluorodeoxyglucose-position emission tomography: a highly accurate imaging modality for the diagnosis of chronic musculoskeletal infections. J Bone Joint Surg Am 2001; 83:651-660.
45. Som P, Atkins HL, Bandoypadhyah D, Fowler JS, MacGregor RR, Matsui K, et al. A fluorinated glucose analog, 2-fluoro-2-deoxy-D-glucose (F-18): nontoxic tracer for rapid tumor detection. J Nucl Med 1980; 21:670-675.