Use of Sulesomab, a radiolabeled antibody fragment, to detect osteomyelitis in diabetic patients with foot ulcers by leukoscintigraphy

Clinical Infectious Diseases

Volumn 28, Issue 6, 1999, Pages 1200-1205

  Harwood, Steven J ^a,b,c,d,e   Valdivia, Sonia ^a,b,c,d   Hung, Guo Long ^a,b,c,d   Quenzer, Ronald W ^a,b,c,d  

^a Bay Pines Dept of Veterans A M C   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c RANCHO LOS AMIGOS NATIONAL REHABILITATION CENTER   (United States)

^d UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^e Bay Pines VA Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; SULESOMAB; UNCLASSIFIED DRUG;

ADULT; ARTICLE; DIABETIC FOOT; DIAGNOSTIC ACCURACY; DIAGNOSTIC IMAGING; DRUG EFFICACY; DRUG SAFETY; FEMALE; HISTOPATHOLOGY; HUMAN; MALE; MICROBIOLOGICAL EXAMINATION; OSTEOMYELITIS; PRIORITY JOURNAL; SCINTIGRAPHY;

EID: 0032982060     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/514791     Document Type: Article

References (37)

1. 1. Newman LG, Waller J, Palestro CJ, et al. Unsuspected osteomyelitis in diabetic foot ulcers: diagnosis and monitoring by leukocyte scanning with In-111-oxyquinoline. JAMA 1991;26:1246-51.
2. 2. Bamberger DM, Daus GP, Gerding DN. Osteomyelitis in the feet of diabetic patients: long-term results, prognostic factors, and the role of antimicrobial and surgical therapy. Am J Med 1987;83:653-60.
3. 3. Ha Van G, Siney H, Danan JP, Sachon C, Grimaldi A. Treatment of osteomyelitis in the diabetic foot. Contribution of conservative surgery. Diabetes Care 1996; 19:1257-60.
4. 4. Gold RH, Tong DJ, Crim JR, Seeger LL. Imaging the diabetic foot. Skeletal Radiol 1995;24:563-71.
5. 5. Cevera JJ, Bolton LL, Kerstein MD. Options for diabetic patients with chronic heel ulcers. J Diabetes Complications 1997;11:358-66.
6. 6. Caputo GM, Cavanagh PR, Ulbrecht JS, Gibbons GW, Karchmer AW. Assessment and management of foot disease in patients with diabetes. N Engl J Med 1994;131:854-60.
7. 7. Crerand S, Dolan M, Laing P, Bird M, Smith ML, Klenerman L. Diagnosis of osteomyelitis in neuropathic foot ulcers. J Bone Joint Surg Br 1996; 78:51-5,
8. 8. Chantelau E, Tanudjaja T, Altenhofer F, Ersanli Z, Lacigova S, Metzger C. Antibiotic treatment for uncomplicated neuropathic forefoot ulcers in diabetes: a controlled trial. Diabet Med 1996; 13:156-9.
9. 9. Gold RH, Hawkins RA, Katz RD. Bacterial osteomyelitis: findings on plain radiography, CT, MR, and scintigraphy. Am J Roentgenol 1991 157:365-70.
10. 10. Sciuk J, Brandau W, Vollet B, et al. Comparison of technetium-99m polyclonal human immunoglobulin and technetium-99m monoclonal antibodies for imaging chronic osteomyelitis. Eur J Nucl Med 1991; 18:401-7.
11. 11. Seabold JE, Flickinger FW, Kao SCS, et al. Indium-111-leukocyte/technetium-99m-MDP bone und magnetic resonance imaging: difficulty of diagnosing osteomyelitis in patients with neuropathic osteoarthropathy. J Nucl Med 1990;31:549-56.
12. 12. Harvey J, Cohen MM. Technetium-99-labeled leukocytes in diagnosing diabetic osteomyelitis in the foot. J Foot Ankle Surg 1997;36:209-14.
13. 13. Wegener WA, Alavi A. Diagnostic imaging of musculoskeletal infection. Orthop Clin North Am 1991;22:401-18.
14. 14. Gupta NC, Prezio JA. Radionuclide imaging in osteomyelitis. Semin Nucl Med 1988; 18:287-99.
15. 15. Schauweeker DS, Park HM, Burt RW, et al. Combined bone scintigraphy and indium-111 leukocyte scans in neuropathic foot disease. J Nucl Med 1988;29:1651-5.
16. 16. Keenan AM, Tindel NL, Alavi A. Diagnosis of pedal osteomyelitis in diabetic patients using current scintigraphic techniques. Arch Intern Med 1989; 149:2262-6.
17. 17. Kolindou A, Liu Y, Ozker K, et al. In-111 WBC imaging of osteomyelitis in patients with underlying bone scan abnormalities. Clin Nucl Med 1996;21:183-91.
18. 18. Rojas-Burke J. Health officials reactions to infection mishaps. J Nucl Med 1992;33:13N-27N.
19. 19. Locher JT, Seybold K, Andres RY, et al. Imaging of inflammatory and infectious lesions after injection of radio-iodinated monoclonal antigranulocyte antibodies. Nucl Med Commun 1986;7:659-70.
20. 20. Joseph K, Höffken H, Damann V. In-vivo-Markierung von Granulozyten mit Tc-99in-markierten monoklonalen Antikorpern: Erste klinische Ergebnisse. European-American Communications in Nuclear Medicine 1987; 18:223-6.
21. 21. Becker W, Goldenberg DM, Wolf F. The use of monoclonal antibodies and antibody fragments in the imaging of infectious lesions. Semin Nucl Med 1994;24:142-53.
22. 22. Becker W, Palestro CJ, Winship J, et al. Rapid imaging of infections with a monoclonal antibody fragment (LeukoScan). Clin Orthop 1996; 329: 263-72.
23. 23. Harwood SJ, Camblin JG, Hakki S, et al. Use of technetium antigranulocyte monoclonal antibody Fab' fragments for the detection of osteomyelitis. Cell Biophys 1994;24/25:99-107.
24. 24. Hakki S, Harwood SJ, Morrissey MA, et al. Comparative study of monoclonal antibody scan in diagnosing orthopaedic infection. Clin Orthop 1997;335:275-85.
25. 25. Hansen HJ, Goldenberg DM, Newman ES, Grebenau R, Sharkey RM. Characterization of second-generation monoclonal antibodies against carcinoembryonic antigen. Cancer 1993;71:3478-85.
26. 26. Product information: ELISA test system for human antibodies to mouse IgG. Morris Plains, NJ: Immunomedics, 1990, brochure 10C016.
27. 27. Product information: ELISA test system for human antibodies to mouse IgG fragments. Morris Plains, NJ: Immunomedics, 1990; brochure 10C015.
28. 28. Weinstein D, Wang A, Chambers R, Stewart CA, Motz HA. Evaluation of magnetic resonance imaging in the diagnosis of osteomyelitis in diabetic foot infections. Foot Ankle 1993;14:18-22.
29. 29. Croll SD, Nicholas GG, Osborne MA, Wasser TE, Jones S. Role of magnetic resonance imaging in the diagnosis of osteomyelitis in diabetic foot infections. J Vasc Surg 1996;24:266-70.
30. 30. Horrowitz JD, Durham JR, Nease DB, Lukens ML, Wright JG, Smead WL. Prospective evaluation of magnetic resonance imaging in the management of acute diabetic foot infections. Ann Vasc Surg 1993;7:44-50.
31. 31. Levine SE, Neagle CE, Esterhai JL, Wright DG, Dalinka MK. Magnetic resonance imaging for the diagnosis of osteomyelitis in the diabetic patient with a foot ulcer. Foot Ankle Int 1994; 15:151-6.
32. 32. Wang A, Weinstein D, Greenfield L, et al. MRI and diabetic foot infections. Magn Reson Imaging 1990;8:805-9.
33. 33. Williamson MR, Quenzer RW, Rosenbergh RD, et al. Osteomyelitis: sensitivity of 0.064 T MRI, three-phase bone scanning and indium scanning with biopsy proof. Magn Reson Imaging 1991;9:945-8.
34. 34. Mader JT, Calhoun J. Osteomyelitis. In: Mandell GJ, Bennett JE, Dolin R, eds. Principles and practice of infectious disease. 4th ed. New York: Churchill Livingstone, 1995:1039-51.
35. 35. Newman LG, Waller J, Palestro CJ, et al. Leukocyte scanning with 111 In is superior to magnetic resonance imaging in diagnosis of clinically unsuspected osteomyelitis in diabetic foot ulcers. Diabetes Care 1992; 15:1527-30.
36. 36. Newman LG. Imaging techniques in the diabetic foot. Clin Podiatr Med Surg 1995; 12:75-86.
37. 37. Limpman BT, Colier BD, Carrera GF, et al. Detection of osteomyelitis in the neuropathic foot: nuclear medicine, MRI, and conventional radiography. Clin Nucl Med 1998;23:77-82.