Nuclear localization of γ-tubulin affects E2F transcriptional activity and S-phase progression

FASEB Journal

Volumn 25, Issue 11, 2011, Pages 3815-3827

  Höög, Greta ^a   Zarrizi, Reihaneh ^a   Von Stedingk, Kristoffer ^a   Jonsson, Kristina ^a   Alvarado Kristensson, Maria ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Cell cycle progression; Cell signaling; Signal transduction

Indexed keywords

ALPHA TUBULIN; CYCLIN E; GAMMA TUBULIN; HISTONE; MUTANT PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR E2F2; TRANSCRIPTION FACTOR E2F3; TRANSCRIPTION FACTOR E2F6;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL NUCLEUS; CENTROSOME; COMPLEX FORMATION; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MAMMAL CELL; MICROTUBULE; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE, TUMOR; CHROMATIN; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; HUMANS; MICE; NIH 3T3 CELLS; NUCLEAR LOCALIZATION SIGNALS; OSTEOSARCOMA; S PHASE; TRANSCRIPTIONAL ACTIVATION; TUBULIN;

MAMMALIA;

EID: 80355148509     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-187484     Document Type: Article

References (36)

1. Trimarchi, J. M., and Lees, J. A. (2002) Sibling rivalry in the E2F family. Nat. Rev. Mol. Cell. Biol. 3, 11-20 (Pubitemid 135709914)
2. Schiebel, E. (2000) gamma-Tubulin complexes: binding to the centrosome, regulation and microtubule nucleation. Curr. Opin. Cell Biol. 12, 113-118
3. Alvarado-Kristensson, M., Rodriguez, M. J., Silio, V., Valpuesta, J. M., and Carrera, A. C. (2009) SADB phosphorylation of gamma-tubulin regulates centrosome duplication. Nat. Cell Biol. 11, 1081-1092
4. Muller, H., Fogeron, M. L., Lehmann, V., Lehrach, H., and Lange, B. M. (2006) A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint. Science 314, 654-657 (Pubitemid 44646391)
5. Moudjou, M., Bordes, N., Paintrand, M., and Bornens, M. (1996) gamma-Tubulin in mammalian cells: the centrosomal and the cytosolic forms. J. Cell Sci. 109(Pt. 4), 875-887 (Pubitemid 26134390)
6. Lesca, C., Germanier, M., Raynaud-Messina, B., Pichereaux, C., Etievant, C., Emond, S., Burlet-Schiltz, O., Monsarrat, B., Wright, M., and Defais, M. (2005) DNA damage induce gammatubulin- RAD51 nuclear complexes in mammalian cells. Oncogene 24, 5165-5172 (Pubitemid 41192433)
7. Korver, W., Guevara, C., Chen, Y., Neuteboom, S., Bookstein, R., Tavtigian, S., and Lees, E. (2003) The product of the candidate prostate cancer susceptibility gene ELAC2 interacts with the gamma-tubulin complex. Int. J. Cancer 104, 283-288 (Pubitemid 36249810)
8. Andersen, J. S., Lyon, C. E., Fox, A. H., Leung, A. K., Lam, Y. W., Steen, H., Mann, M., and Lamond, A. I. (2002) Directed proteomic analysis of the human nucleolus. Curr. Biol. 12, 1-11
9. Mendez, J., and Stillman, B. (2000) Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis. Mol. Cell. Biol. 20, 8602-8612
10. Kramer, A., Mailand, N., Lukas, C., Syljuasen, R. G., Wilkinson, C. J., Nigg, E. A., Bartek, J., and Lukas, J. (2004) Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase. Nat. Cell Biol. 6, 884-891 (Pubitemid 39207253)
11. Black, E. P., Hallstrom, T., Dressman, H. K., West, M., and Nevins, J. R. (2005) Distinctions in the specificity of E2F function revealed by gene expression signatures. Proc. Natl. Acad. Sci. U. S. A. 102, 15948-15953 (Pubitemid 41552848)
12. Muller, H., Bracken, A. P., Vernell, R., Moroni, M. C., Christians, F., Grassilli, E., Prosperini, E., Vigo, E., Oliner, J. D., and Helin, K. (2001) E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis. Genes Dev. 15, 267-285 (Pubitemid 32155143)
13. Lees, J. A., Saito, M., Vidal, M., Valentine, M., Look, T., Harlow, E., Dyson, N., and Helin, K. (1993) The retinoblastoma protein binds to a family of E2F transcription factors. Mol. Cell. Biol. 13, 7813-7825 (Pubitemid 23354306)
14. Gaubatz, S., Wood, J. G., and Livingston, D. M. (1998) Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6. Proc. Natl. Acad. Sci. U. S. A. 95, 9190-9195 (Pubitemid 28506207)
15. Liu, K., Luo, Y., Lin, F. T., and Lin, W. C. (2004) TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival. Genes Dev. 18, 673-686 (Pubitemid 38489935)
16. Alvarado-Kristensson, M., Melander, F., Leandersson, K., Ronnstrand, L., Wernstedt, C., and Andersson, T. (2004) p38- MAPK signals survival by phosphorylation of caspase-8 and caspase-3 in human neutrophils. J. Exp. Med. 199, 449-458 (Pubitemid 38233829)
17. Alvarado-Kristensson, M., Porn-Ares, M. I., Grethe, S., Smith, D., Zheng, L., and Andersson, T. (2002) p38 Mitogen-activated protein kinase and phosphatidylinositol 3-kinase activities have opposite effects on human neutrophil apoptosis. FASEB J. 16, 129-131
18. Hiebert, S. W., Chellappan, S. P., Horowitz, J. M., and Nevins, J. R. (1992) The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev. 6, 177-185
19. Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S., and Mesirov, J. P. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. U. S. A. 102, 15545-15550 (Pubitemid 41528093)
20. Jamshidi-Parsian, A., Dong, Y., Zheng, X., Zhou, H. S., Zacharias, W., and McMasters, K. M. (2005) Gene expression profiling of E2F-1-induced apoptosis. Gene 344, 67-77 (Pubitemid 40126794)
21. Dennis, G., Jr., Sherman, B. T., Hosack, D. A., Yang, J., Gao, W., Lane, H. C., and Lempicki, R. A. (2003) DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol. 4, P3
22. Huang da, W., Sherman, B. T., and Lempicki, R. A. (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57
23. Qin, X. Q., Chittenden, T., Livingston, D. M., and Kaelin, W. G., Jr. (1992) Identification of a growth suppression domain within the retinoblastoma gene product. Genes Dev. 6, 953-964
24. Weinmann, A. S., and Farnham, P. J. (2002) Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation. Methods 26, 37-47 (Pubitemid 34969216)
25. Hosack, D. A., Dennis, G., Jr., Sherman, B. T., Lane, H. C., and Lempicki, R. A. (2003) Identifying biological themes within lists of genes with EASE[b]. Genome Biol. 4, R70
26. Wan, Z., Zhi, N., Wong, S., Keyvanfar, K., Liu, D., Raghavachari, N., Munson, P. J., Su, S., Malide, D., Kajigaya, S., and Young, N. S. (2010) Human parvovirus B19 causes cell cycle arrest of human erythroid progenitors via deregulation of the E2F family of transcription factors. J. Clin. Invest. 120, 3530-3544
27. Geng, Y., Eaton, E. N., Picon, M., Roberts, J. M., Lundberg, A. S., Gifford, A., Sardet, C., and Weinberg, R. A. (1996) Regulation of cyclin E transcription by E2Fs and retinoblastoma protein. Oncogene 12, 1173-1180 (Pubitemid 26127247)
28. Q01094 (E2F1-HUMAN). UniProt Protein Knowledgebase. Retrieved December 2, 2010, from http://www.uniprot.org/uniprot/Q01094
29. Helin, K., Wu, C. L., Fattaey, A. R., Lees, J. A., Dynlacht, B. D., Ngwu, C., and Harlow, E. (1993) Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative transactivation. Genes Dev. 7, 1850-1861 (Pubitemid 23312940)
30. Vidal, M., Braun, P., Chen, E., Boeke, J. D., and Harlow, E. (1996) Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system. Proc. Natl. Acad. Sci. U. S. A. 93, 10321-10326 (Pubitemid 26314620)
31. Mudryj, M., Hiebert, S. W., and Nevins, J. R. (1990) A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway. EMBO J. 9, 2179-2184
32. Jorissen, R. N., Gibbs, P., Christie, M., Prakash, S., Lipton, L., Desai, J., Kerr, D., Aaltonen, L. A., Arango, D., Kruhoffer, M., Orntoft, T. F., Andersen, C. L., Gruidl, M., Kamath, V. P., Eschrich, S., Yeatman, T. J., and Sieber, O. M. (2009) Metastasis-associated gene expression changes predict poor outcomes in patients with Dukes stage B and C colorectal cancer. Clin. Cancer Res. 15, 7642-7651
33. Sancar, A., Lindsey-Boltz, L. A., Unsal-Kacmaz, K., and Linn, S. (2004) Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu. Rev. Biochem. 73, 39-85 (Pubitemid 39050363)
34. Giacinti, C., and Giordano, A. (2006) RB and cell cycle progression. Oncogene 25, 5220-5227 (Pubitemid 44299080)
35. Doxsey, S., McCollum, D., and Theurkauf, W. (2005) Centrosomes in cellular regulation. Annu. Rev. Cell Dev. Biol. 21, 411-434 (Pubitemid 41740641)
36. Carrera, A. C., and Alvarado-Kristensson, M. (2009) SADB kinases license centrosome replication. Cell. Cycle 8, 4005-4006