Identifying the effects of BRCA1 mutations on homologous recombination using cells that express endogenous wild-type BRCA1

Journal of Visualized Experiments

Volumn , Issue 48, 2010, Pages

  Parvin, Jeffrey ^a   Chiba, Natsuko ^b   Ransburgh, Derek ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 80355132829     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/2468     Document Type: Article

References (14)

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11. Snouwaert, J. N. et al. BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a brca1 transgene. Oncogene 18, 7900-7907 (1999).
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