Coumarin incorporated triazoles: A new class of anticonvulsants

Acta Poloniae Pharmaceutica - Drug Research

Volumn 68, Issue 6, 2011, Pages 889-895

  Bhat, Mashooq A ^a   Al Omar, Mohammed A ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

1,2,4 triazoles; Coumarin; MES test

Indexed keywords

CARBAMAZEPINE; COUMARIN DERIVATIVE; DEZINAMIDE; DIAZEPAM; ETHOSUXIMIDE; LAMOTRIGINE; PHENYTOIN; REMACEMIDE; RUFINAMIDE; TRIAZOLE DERIVATIVE; VALPROIC ACID; ZONISAMIDE;

ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; DRUG POTENTIATION; DRUG SCREENING; FEMALE; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; PHARMACOPHORE; THREE DIMENSIONAL IMAGING;

ANIMALS; ANTICONVULSANTS; COUMARINS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ELECTRIC STIMULATION; INJECTIONS, INTRAPERITONEAL; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MOTOR ACTIVITY; NEUROTOXICITY SYNDROMES; PENTYLENETETRAZOLE; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS; TRIAZOLES;

EID: 80355125863     PISSN: 00016837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Wasteralin, C.: in Basic Neurochemistry: Molecular, Cellular and Medical Aspects, Siegel G.J., Agranoff B.W., Albers B.W. Eds., p. 797, Raven Press, New York 1989.
2. th edn., p. 521, McGraw Hill, New York 2001.
3. Coatsworth J.J.: Studies on the clinical efficacy of marketed antiepileptic drugs, UNINDS Monograph No. 12, 73-15, HEW publication, U.S. Government Printing Office, Washington 1971.
4. Rana A., Siddiqui N., Khan S.A., Haque, S.E., Bhat M.A.: Eur. J. Med. Chem. 43, 1114 (2008).
5. Siddiqui N., Rana A., Khan S.A., Bhat M.A., Haque S.E.: Bioorg. Med. Chem. Lett. 17, 4178 (2007).
6. Siddiqui N., Pandeya S. N., Khan S.A., Stables J., Rana A., Alam M., Arshad M.F., Bhat M.A.: Bioorg. Med. Chem. Lett. 17, 255 (2007).
7. Bhat M.A., Siddiqui N., Khan S.A.: Acta Pol. Pharm. Drug Res. 65, 235 (2008).
8. Siddiqui N., Bhat M.A., Khan S.A., Ahsan W., Alam M.S.: J. Chinese Chem. Soc. 55, 1326 (2008).
9. Almsirad A., Tabatabai S.A., Faizi M.: Bioorg. Med. Chem. Lett. 14, 6057 (2004).
10. Shiradkar M.R., Ghodake M., Bothara K.G., Bhandari S.V., Nikalje A., Akula K.C. Desai N.C., Burange P.J.: Arkivoc 14, 58 (2007).
11. Anticonvulsant screening project, Antiepileptic Drug Development Program. National Institutes of Health, DHEW publ. (NIH), (US), pp. 78-1093 (1978).
12. Kupferberg H.J., Stables J.P.: in Challenge Epilepsy - New Antiepileptic Drugs. Stefen H., Kramer G., Mamoli B. Eds., p. 7, Blackwell Sciences, Berlin 1998.
13. Clark C.R., Wells M.J.M., Sansom, R.T., Norris G.N., Dockens R.C., Ravis W.R.: J. Med. Chem. 27, 779 (1984).
14. Yogeeswari P., Sriram D., Saraswat V., Ragavendran J. V., Kumar M.M., Murugesan S., Thirumurugan R., Stables J.P.: Eur. J. Pharm. Sci. 20, 341 (2003).
15. Farar V. A., Ciechanowicz-Rutkowska M., Grochowski J., Serda P., Pilati T., Filippini G., Hinko C.N. et al.: J. Med. Chem. 36, 3517 (1993).
16. Wong M.G., Defina J.A., Andrews P.R.: J. Med. Chem. 29, 562 (1986).
17. Brooks B.R., Bruccoleri R.E., Olafson B.D., States D.J., Swaminathan S., Karplus M.: J. Comput. Chem. 4, 187 (1983).
18. Cacic M., Trkovnik M., Cacic F., Has-Schon E.: Molecules 11, 134 (2006).
19. Bhat M. A., Siddiqui N., Khan S.A., Mohamed M.I.: Acta Pol. Pharm. Drug Res. 66, 625 (2009).
20. Lien E.J., Liao R.C.H., Shinouda H.G.: J. Pharm. Sci. 68, 463 (1979).
21. Pandeya S.N., Yogeeswari P., Stables J.P.: Eur. J. Med. Chem. 35, 879 (2000).