Synthesis and anticonvulsant activity of sulfonamide derivatives-hydrophobic domain

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 1, 2007, Pages 255-259

  Siddiqui, Nadeem ^a   Pandeya, Surendra N ^b   Khan, Suroor A ^a   Stables, James ^c   Rana, Arpana ^a   Alam, Mahfuz ^a   Arshad, Md Faiz ^a   Bhat, Mashooq A ^a  

^a HAMDARD UNIVERSITY   (India)

^b Dr KNModi Institute of Pharmaceutical Education & Research Modinagar   (India)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Anticonvulsant; Benzothiazole; Sulfonamide

Indexed keywords

CARBAMAZEPINE; ETHOSUXIMIDE; N (3 CHLOROPHENYL) 4 [[(METHYLAMINO)CARBONOTHIONYL]AMINO]BENZENE SULFONAMIDE; N (6 FLUORO 1,3 BENZOTHIAZOL 2 YL) 4 [[AMINO)CARBONOTHIOYL]AMINO]BENZENE SULFONAMIDE; SULFONAMIDE; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROPHOBICITY; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; RAT; SPECTROSCOPY;

ANIMALS; ANTICONVULSANTS; HYDROPHOBICITY; MALE; MICE; MICE, INBRED STRAINS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; SULFONAMIDES;

EID: 33845603888     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.09.053     Document Type: Article

References (12)

1. van Bebenburg W., Steinmetz G., and Thielek K. Chem. Ztg. 103 (1979) 387
2. Shank R.P., Gordoeki J.F., and Streter A.J. Epilepsia 41 (2000) 53
3. Kubota M., Nishi-Nagase M., and Sakakihora Y. Brain Dev. 22 (2000) 230
4. French J.A. Epilepsia 40 (1999) 11
5. Micale N., Zappala M., Zuccala G., Menniti F.S., Ferreri G., De Sarro G., and Grasso S. Farmaco 60 (2005) 231
6. Yogeeswari P., Sriram D., Thirumurugan R., Raghavendran J.V., Sudhan K., Pavana R.K., and Stables J. J. Med. Chem. 48 (2005) 6202
7. Pandeya S.N., Senthil Raja A., and Stables J.P. J. Pharm. Pharmaceut. Sci. 5 (2002) 266
8. Nadkarni A.B., Kamath R.V., and Khadse G.B. Ind. J. Heterocycl. Chem. 9 (2000) 309
9. 3): 7.20-7.84 (m, 7H, Ar-H); 12.31 (s, 3H, NH).
10. 3); 10.07(s, 3H, NH, NHC{double bond, long}S).
11. Krall R.L., Penry J.K., White B.G., Kupferberg H.J., and Swinyard E.A. Epilepsia 19 (1978) 409
12. Pandeya S.N., Kohli S., Siddiqui N., and Stables J.P. Pol. J. Pharmacol. 55 (2003) 565