Fast simultaneous quantitative analysis of FTY720 and its metabolite FTY720-P in human blood by on-line solid phase extraction coupled with liquid chromatography-tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 58, Issue 1, 2012, Pages 102-112

  Emotte, Corinne ^a   Deglave, Fany ^a   Heudi, Olivier ^a   Picard, Franck ^a   Kretz, Olivier ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

FTY720; FTY720 P; Human blood; LC MS MS; On line SPE

Indexed keywords

ACETONITRILE; FINGOLIMOD; METHANOL; PHOSPHORIC ACID;

ACCURACY; ARTICLE; BLOOD; BLOOD SAMPLING; CONTROLLED STUDY; DILUTION; DRUG DETERMINATION; DRUG STABILITY; ELECTROSPRAY; FREEZE THAWING; HUMAN; HUMAN TISSUE; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; RELIABILITY; REPRODUCIBILITY; ROOM TEMPERATURE; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; STRUCTURE ACTIVITY RELATION; TANDEM MASS SPECTROMETRY;

CALIBRATION; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; HUMANS; PHOSPHORIC ACID ESTERS; PROPYLENE GLYCOLS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPHINGOSINE; TANDEM MASS SPECTROMETRY;

EID: 80255130592     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.09.021     Document Type: Article

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