Tumour necrosis factor-stimulated gene (TSG)-6 controls epithelial-mesenchymal transition of proximal tubular epithelial cells

International Journal of Biochemistry and Cell Biology

Volumn 43, Issue 12, 2011, Pages 1739-1746

  Bommaya, Girish ^a   Meran, Soma ^a   Krupa, Aleksandra ^a   Phillips, Aled Owain ^a   Steadman, Robert ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

CD44; Fibrosis; Hyaladherin; Hyaluronan; Myofibroblast; TSG 6

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CELL PROTEIN; HERMES ANTIGEN; HYALURONIC ACID; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; TUMOUR NECROSIS FACTOR STIMULATED PROTEIN 6; UNCLASSIFIED DRUG; UVOMORULIN;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY FIBROSIS; KIDNEY TUBULE CELL; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROXIMAL TUBULAR EPITHELIAL CELL;

ANTIGENS, CD44; CADHERINS; CELL ADHESION MOLECULES; CELL LINE; CELL MOVEMENT; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; HYALURONIC ACID; KIDNEY TUBULES, PROXIMAL; RNA, SMALL INTERFERING; TRANSFORMING GROWTH FACTOR BETA1;

EID: 80255129362     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2011.08.009     Document Type: Article

References (56)

1. S. Banerji, A.J. Wright, M. Noble, D.J. Mahoney, I.D. Campbell, and A.J. Day Structures of the Cd44-hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction Nat Struct Mol Biol 14 2007 234 239 (Pubitemid 46355571)
2. A. Bohle, H. Mackensen-Haen, and H.V. Gise Significance of tubulointerstitial changes in the renal cortex for the excretory function and concentration ability of the kidney: a morphometric contribution Am J Nephrol 7 1987 421 433 (Pubitemid 18025635)
3. A. Bohle, S. Mackensen-Haen, H. von Gise, K.E. Grund, M. Wehrmann, and C. Batz The consequences of tubulo-interstitial changes for renal function in glomerulopathies. A morphometric and cytological analysis Pathol Res Pract 186 1990 135 144 (Pubitemid 20097957)
4. J. Cheng, and J.P. Grande Transforming growth factor-beta signal transduction and progressive renal disease Exp Biol Med (Maywood) 227 2002 943 956 (Pubitemid 36008302)
5. A.J. Day, and C.A. de la Motte Hyaluronan cross-linking: a protective mechanism in inflammation? Trends Immunol 26 2005 637 643 (Pubitemid 41628196)
6. A.J. Day, and G.D. Prestwich Hyaluronan-binding proteins: tying up the giant J Biol Chem 277 2002 4585 4588 (Pubitemid 34968483)
7. A. Desmouliere, I.A. Darby, and G. Gabbiani Normal and pathologic soft tissue remodeling: role of the myofibroblast, with special emphasis on liver and kidney fibrosis LAb Invest 83 2003 1689 1707 (Pubitemid 38018532)
8. A. Desmouliere, and G. Gabbiani Myofibroblast differentiation during fibrosis Exp Nephrol 3 1995 134 139
9. M. Essawy, O. Soylemezoglu, E.C. Muchaneta-Kubara, J. Shortland, C.B. Brown, and A.M. el Nahas Myofibroblasts and the progression of diabetic nephropathy Nephrol Dial Transplant 12 1997 43 50 (Pubitemid 27046200)
10. S.P. Evanko, M.I. Tammi, R.H. Tammi, and T.N. Wight Hyaluronan-dependent pericellular matrix Adv Drug Deliv Rev 59 2007 1351 1365 (Pubitemid 350088257)
11. M. Fragiadaki, and R.M. Mason Epithelial-mesenchymal transition in renal fibrosis - evidence for and against Int J Exp Pathol 92 2011 143 150
12. G. Gabbiani The myofibroblast in wound healing and fibrocontractive diseases J Pathol 200 2003 500 503 (Pubitemid 36818250)
13. D.S. Goumenos, C.B. Brown, J. Shortland, and A.M. El Nahas Myofibroblasts, predictors of progression of mesangial IgA nephropathy? Nephrol Dial Transplant 9 1994 1418 1425 (Pubitemid 24310284)
14. J. Grande, D. Melder, A. Zinsmeister, and P. Killen Transforming growth factor beta 1 induces collagen IV gene expression in NIH-3T3 cells Lab Invest 69 1993 387 395
15. M. Grande, A. Franzen, J.O. Karlsson, L.E. Ericson, N.E. Heldin, and M. Nilsson Transforming growth factor-beta and epidermal growth factor synergistically stimulate epithelial to mesenchymal transition (EMT) through a MEK-dependent mechanism in primary cultured pig thyrocytes J Cell Sci 115 2002 4227 4236 (Pubitemid 35460694)
16. B. Hinz, and G. Gabbiani Cell-matrix and cell-cell contacts of myofibroblasts: role in connective tissue remodeling Thromb Haemost 90 2003 993 1002 (Pubitemid 38004416)
17. T. Ito, J.D. Williams, S. Al-Assaf, G.O. Phillips, and A.O. Phillips Hyaluronan and proximal tubular cell migration Kidney Int 65 2004 823 833 (Pubitemid 38251058)
18. T. Ito, J.D. Williams, D. Fraser, and A.O. Phillips Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells Am J Pathol 164 2004 1979 1988 (Pubitemid 38669347)
19. T. Ito, J.D. Williams, D.J. Fraser, and A.O. Phillips Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalization J Biol Chem 279 2004 25326 25332 (Pubitemid 38756787)
20. M. Iwano, D. Plieth, T.M. Danoff, C. Xue, H. Okada, and E.G. Neilson Evidence that fibroblasts derive from epithelium during tissue fibrosis J Clin Invest 110 2002 341 350 (Pubitemid 34847966)
21. W. Knudson, D.J. Aguiar, Q. Hua, and C.B. Knudson CD44-anchored hyaluronan-rich pericellular matrices: an ultrastructural and biochemical analysis Exp Cell Res 228 1996 216 228 (Pubitemid 26384652)
22. W. Kriz, B. Kaissling, and M. Le Hir Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy? J Clin Invest 121 2011 468 474
23. A.J. Lewington, B.J. Padanilam, D.R. Martin, and M.R. Hammerman Expression of CD44 in kidney after acute ischemic injury in rats Am J Physiol Regul Integr Comp Physiol 278 2000 R247 R254
24. A. Lewis, R. Steadman, P. Manley, K. Craig, C. de la Motte, and V. Hascall Diabetic nephropathy, inflammation, hyaluronan and interstitial fibrosis Histol Histopathol 23 2008 731 739 (Pubitemid 351552358)
25. S. Mackensen-Haen, R. Bader, K.E. Grund, and A. Bohle Correlations between renal cortical interstitial fibrosis, atrophy of the proximal tubules and impairment of the glomerular filtration rate Clin Nephrol 15 1981 167 1721
26. S. Meran, and R. Steadman Fibroblasts and myofibroblasts in renal fibrosis Int J Exp Pathol 92 2011 158 167
27. S. Meran, D. Thomas, P. Stephens, J. Martin, T. Bowen, and A. Phillips Involvement of hyaluronan in regulation of fibroblast phenotype J Biol Chem 282 2007 25687 25697 (Pubitemid 47372811)
28. S. Meran, D.W. Thomas, P. Stephens, S. Enoch, J. Martin, and R. Steadman Hyaluronan facilitates transforming growth factor-beta1-mediated fibroblast proliferation J Biol Chem 283 2008 6530 6545
29. M.F. Meyer, and G. Kreil Cells expressing the DG42 gene from early Xenopus embryos synthesize hyaluronan Proc Natl Acad Sci USA 93 1996 4543 4547 (Pubitemid 26162798)
30. Y.Y. Ng, T.P. Huang, W.C. Yang, Z.P. Chen, A.H. Yang, and W. Mu Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats Kidney Int 54 1998 864 876 (Pubitemid 28397404)
31. H. Okada, T. Inoue, H. Suzuki, F. Strutz, and E.G. Neilson Epithelial-mesenchymal transformation of renal tubular epithelial cells in vitro and in vivo Nephrol Dial Transplant 6 Suppl. 15 2000 44 46
32. I.S. Roberts, C. Burrows, J.H. Shanks, M. Venning, and L.J. McWilliam Interstitial myofibroblasts: predictors of progression in membranous nephropathy J Clin Pathol 50 1997 123 127 (Pubitemid 27093027)
33. J.-P. Salier, P. Rouet, G. Raguenez, and M. Daveau The inter-α-inhibitor family: from structure to regulation Biochem J 315 1996 1 9
34. N. Sano, K. Kitazawa, and T. Sugisaki Localization and roles of CD44, hyaluronic acid and osteopontin in IgA nephropathy Nephron 89 2001 416 421 (Pubitemid 33135821)
35. W. Selbi, A.J. Day, M.S. Rugg, C. Fulop, C.A. de la Motte, and T. Bowen Overexpression of hyaluronan synthase 2 alters hyaluronan distribution and function in proximal tubular epithelial cells J Am Soc Nephrol 17 2006 1553 1567 (Pubitemid 43794658)
36. W. Selbi, C. de la Motte, V. Hascall, and A. Phillips BMP-7 modulates hyaluronan-mediated proximal tubular cell-monocyte interaction J Am Soc Nephrol 15 2004 1199 1211 (Pubitemid 38526001)
37. W. Selbi, C.A. de la Motte, V.C. Hascall, A.J. Day, T. Bowen, and A.O. Phillips Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells Kidney Int 70 2006 1287 1295 (Pubitemid 44435180)
38. V. Sibalic, X. Fan, J. Loffing, and R.P. Wuthrich Upregulated renal tubular CD44, hyaluronan, and osteopontin in kdkd mice with interstitial nephritis Nephrol Dial Transplant 12 1997 1344 1353 (Pubitemid 27353022)
39. R.M. Simpson, S. Meran, D. Thomas, P. Stephens, T. Bowen, and R. Steadman Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation Am J Pathol 175 2009 1915 1928
40. R.M. Simpson, A. Wells, D. Thomas, P. Stephens, R. Steadman, and A. Phillips Aging fibroblasts resist phenotypic maturation because of impaired hyaluronan-dependent CD44/epidermal growth factor receptor signaling Am J Pathol 176 2010 1215 1228
41. A.P. Spicer, M.L. Augustine, and J.A. McDonald Molecular cloning and charaterization of a putative mouse hyaluronan synthase J Biol Chem 271 1996 23400 23406 (Pubitemid 26314788)
42. A.P. Spicer, and J.A. McDonald Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family J Biol Chem 273 1998 1923 1932 (Pubitemid 28069235)
43. F. Strutz Novel aspects of renal fibrogenesis Nephrol Dial Transplant 10 1995 1526 1532
44. F. Strutz, and G.A. Muller Renal fibrosis and the origin of the renal fibroblast Nephrol Dial Transplant 21 2006 3368 3370 (Pubitemid 44817082)
45. F. Strutz, G.A. Muller, and E.G. Neilson Transdifferentiation: a new angle on renal fibrosis Exp Nephrol 4 1996 267 270 (Pubitemid 26342895)
46. F.M. Strutz EMT and proteinuria as progression factors Kidney Int 75 2009 475 481
47. Y.C. Tian, D. Fraser, L. Attisano, and A.O. Phillips TGF-beta1-mediated alterations of renal proximal tubular epithelial cell phenotype Am J Physiol Renal Physiol 285 2003 F130 F142
48. Y.C. Tian, and A.O. Phillips Interaction between the transforming growth factor-beta type II receptor/Smad pathway and beta-catenin during transforming growth factor-beta1-mediated adherens junction disassembly Am J Pathol 160 2002 1619 1628 (Pubitemid 34525642)
49. J. Webber, R.H. Jenkins, S. Meran, A. Phillips, and R. Steadman Modulation of TGFbeta1-dependent myofibroblast differentiation by hyaluronan Am J Pathol 175 2009 148 160
50. J. Webber, S. Meran, R. Steadman, and A. Phillips Hyaluronan orchestrates transforming growth factor-beta1-dependent maintenance of myofibroblast phenotype J Biol Chem 284 2009 9083 9092
51. A. Wells, E. Larsson, E. Hanas, T. Laurent, R. Hallgren, and G. Tufveson Increased hyaluronan in acutely rejecting human kidney grafts Transplantation 55 1993 1346 1349 (Pubitemid 23183249)
52. A.F. Wells, E. Larsson, A. Tengblad, B. Fellstrom, G. Tufveson, and L. Klareskog The localization of hyaluronan in normal and rejected human kidneys Transplantation 50 1990 240 243 (Pubitemid 20259169)
53. J. Yang, and Y. Liu Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis Am J Pathol 159 2001 1465 1475 (Pubitemid 32947976)
54. M. Zeisberg, G. Bonner, Y. Maeshima, P. Colorado, G.A. Muller, and F. Strutz Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation Am J Pathol 159 2001 1313 1321 (Pubitemid 32947961)
55. X.L. Zhang, W. Selbi, C. de la Motte, V. Hascall, and A. Phillips Renal proximal tubular epithelial cell transforming growth factor-beta1 generation and monocyte binding Am J Pathol 165 2004 763 773 (Pubitemid 39129284)
56. X.L. Zhang, N. Topley, T. Ito, and A. Phillips Interleukin-6 regulation of transforming growth factor (TGF)-beta receptor compartmentalization and turnover enhances TGF-beta1 signaling J Biol Chem 280 2005 12239 12245