Loss of membrane phospholipid asymmetry in platelets and red cells may be associated with calcium-induced shedding of plasma membrane and inhibition of aminophospholipid translocase

BBA - Biomembranes

Volumn 1026, Issue 2, 1990, Pages 153-160

  Comfurius, Paul ^a   Senden, Joan M G ^a   Tilly, Roland H J ^a   Schroit, Alan J ^b   Bevers, Edouard M ^a   Zwaal, Robert F A ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Aminophospholipid translocase; Erythrocyte; Flip flop; Lipid asymmetry; Membrane shedding; Platelet; Prothrombinase

Indexed keywords

AMINOPHOSPHOLIPID; CALCIUM; MEMBRANE LIPID;

ARTICLE; CELL MEMBRANE; ERYTHROCYTE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; THROMBOCYTE;

ADENOSINE TRIPHOSPHATE; BLOOD PLATELETS; CALCIMYCIN; CALCIUM; CALPAIN; CARRIER PROTEINS; CELL COMPARTMENTATION; EGTAZIC ACID; ENZYME ACTIVATION; ERYTHROCYTE MEMBRANE; HUMAN; IN VITRO; MEMBRANE LIPIDS; MEMBRANE PROTEINS; PHOSPHATIDYLSERINES; PHOSPHOLIPIDS; PLATELET ACTIVATION; SULFHYDRYL COMPOUNDS; SUPPORT, NON-U.S. GOV'T; THROMBOPLASTIN;

EID: 0025301753     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/0005-2736(90)90058-V     Document Type: Article

References (48)

1. Bidirectional transbilayer lipid movement in human platelets as vizualized by the fluorescent membrane probe 1-[4-(trimethylammonio)phenyl]-6-phenyl-1,3,5-hexatriene.