Effect of salt concentration on the conformation of TAR RNA and its association with aminoglycoside antibiotics

Biochemistry

Volumn 50, Issue 44, 2011, Pages 9434-9445

  Smith, Amy L ^a   Kassman, Joseph ^b   Srour, Khalid J ^a   Soto, Ana Maria ^a  

^a TOWSON UNIVERSITY   (United States)

^b The College of New Jersey   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO GROUP; AMINOGLYCOSIDE ANTIBIOTICS; BINDING AFFINITIES; BINDING SPECIFICITIES; BIOLOGICAL TARGETS; BOUND LIGANDS; CELLULAR PROCESS; CHARGE-CHARGE INTERACTIONS; ELECTROSTATIC CONTRIBUTIONS; GENTAMYCIN; NON-COVALENT INTERACTION; POSITIVE CHARGES; PROTONATED; SALT CONCENTRATION; SPECIFIC BINDING; TOBRAMYCIN; VAN DER WAALS;

ANTIBIOTICS; BINDING ENERGY; ELECTROSTATICS; HYDROGEN; HYDROGEN BONDS; OPTIMIZATION; TAR; VAN DER WAALS FORCES;

RNA;

AMINOGLYCOSIDE ANTIBIOTIC AGENT; GENTAMICIN; KANAMYCIN B; PAROMOMYCIN; SODIUM CHLORIDE; TOBRAMYCIN;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; HYDROGEN BOND; PRIORITY JOURNAL; PROTON TRANSPORT; RNA BINDING; RNA CONFORMATION; STATIC ELECTRICITY;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; HYDROCHLORIC ACID; HYDROXIDES; MAGNESIUM CHLORIDE; NUCLEIC ACID CONFORMATION; POTASSIUM COMPOUNDS; PROTEIN BINDING; REV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; RNA, VIRAL; STATIC ELECTRICITY;

EID: 80155166051     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200835t     Document Type: Article

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