The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections

Journal of Allergy and Clinical Immunology

Volumn 128, Issue 5, 2011, Pages 1006-1014

  Howell, Michael D ^a,b   Gao, Peisong ^c   Kim, Byung Eui ^a   Lesley, Leighann J ^a   Streib, Joanne E ^a   Taylor, Patricia A ^a   Zaccaro, Daniel J ^d   Boguniewicz, Mark ^a,b   Beck, Lisa A ^e   Hanifin, Jon M ^f   Schneider, Lynda C ^g   Hata, Tissa R ^h   Gallo, Richard L ^h   Kaplan, Mark H ⁱ   Barnes, Kathleen C ^c   Leung, Donald Y M ^a,b  

^a DEPARTMENT OF MEDICINE   (United States)

^b Children's Hospital Colorado   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Rho Federal Systems Division Inc   (United States)

^e UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^f OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^g BOSTON CHILDREN S HOSPITAL   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Atopic dermatitis; eczema; infection; STAT6; virus

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 14; STAT6 PROTEIN;

ADULT; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; FEMALE; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; INFECTION RISK; KAPOSI VARICELLIFORM ERUPTION; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN BIOPSY; VACCINIA; VACCINIA VIRUS; VIRAL SKIN DISEASE; VIRUS REPLICATION;

ADULT; ANIMALS; DERMATITIS, ATOPIC; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KAPOSI VARICELLIFORM ERUPTION; MICE; MICE, TRANSGENIC; POLYMORPHISM, SINGLE NUCLEOTIDE; SKIN DISEASES, VIRAL; SMALLPOX VACCINE; STAT6 TRANSCRIPTION FACTOR; VACCINIA; VACCINIA VIRUS;

EID: 80055097824     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.06.003     Document Type: Article

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