In vivo assessment of local effects after application of bone screws delivering bisphosphonates into a compromised cancellous bone site

Clinical Biomechanics

Volumn 26, Issue 10, 2011, Pages 1039-1043

  Roshan Ghias, Alireza ^a   Arnoldi, Joerg ^b,c   Procter, Philip ^b,d   Pioletti, Dominique P ^a  

^a EPFL   (Switzerland)

^b Stryker Osteosynthesis ^*  (Switzerland)

^c SAHLGRENSKA ACADEMY AT UNIVERSITY OF GOTHENBURG   (Sweden)

^d BRUNEL UNIVERSITY   (United Kingdom)

Author keywords

Biomechanics; Bone screws; Cancellous bone; Drug delivery; Histology

Indexed keywords

BISPHOSPHONATES; BONE SCREW; BONE SCREWS; BONE VOLUME FRACTION; CANCELLOUS BONE; CONTROL GROUPS; IN-VIVO; LOCAL DELIVERY; LOCAL DRUG DELIVERY; LOCAL EFFECTS; MICRO CT; PULL-OUT FORCE; SCREW FIXATION; TIME POINTS;

ANIMALS; BIOMECHANICS; BONE; COMPUTERIZED TOMOGRAPHY; DRUG DELIVERY; MECHANICAL TESTING; TITRATION;

SCREWS;

BISPHOSPHONIC ACID DERIVATIVE; ZOLEDRONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MASS; BONE SCREW; BONE TRANSPLANTATION; CANCELLOUS BONE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; IN VIVO STUDY; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BONE AND BONES; BONE DENSITY CONSERVATION AGENTS; BONE SCREWS; COATED MATERIALS, BIOCOMPATIBLE; DIPHOSPHONATES; IMIDAZOLES; MATERIALS TESTING; PROSTHESIS IMPLANTATION; RABBITS; SURFACE PROPERTIES;

EID: 80055095812     PISSN: 02680033     EISSN: 18791271     Source Type: Journal    
DOI: 10.1016/j.clinbiomech.2011.06.004     Document Type: Article

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