Hyperbaric oxygen therapy and promoting neurological recovery following nerve trauma

Undersea and Hyperbaric Medicine

Volumn 38, Issue 5, 2011, Pages 345-366

  Nazario, Juan ^a   Kuffler, Damien P ^b  

^a Dept of Hyperbaric Medicine   (Puerto Rico)

^b UNIVERSITY OF PUERTO RICO   (Puerto Rico)

Author keywords

[No Author keywords available]

Indexed keywords

SIGNAL PEPTIDE;

ANGIOGENESIS; ANIMAL; ANIMAL MODEL; BACTERIAL INFECTION; CENTRAL NERVOUS SYSTEM DISEASE; HUMAN; HYPERBARIC OXYGEN; INJURY; METHODOLOGY; NERVE FIBER; NERVE REGENERATION; PERIPHERAL NEUROPATHY; PHYSIOLOGY; RAT; REVIEW; WOUND HEALING;

ANIMALS; AXONS; BACTERIAL INFECTIONS; CENTRAL NERVOUS SYSTEM DISEASES; HUMANS; HYPERBARIC OXYGENATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, ANIMAL; NEOVASCULARIZATION, PHYSIOLOGIC; NERVE REGENERATION; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; WOUND HEALING; WOUNDS AND INJURIES;

EID: 80055092993     PISSN: 10662936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (241)

1. Das RH, van Osch GJ, Kreukniet M, Oostra J, Weinans H, Jahr H. Effects of individual control of pH and hypoxia in chondrocyte culture. J Orthop Res. 2010;4:537-545.
2. Qu CJ, Poytakangas T, Jauhiainen M, Auriola S, Lammi MJ. Glucosamine sulphate does not increase extracellular matrix production at low oxygen tension. Cell and Tissue Res. 2009;337:103-111.
3. Guaccio A, Borselli C, Oliviero O, Netti PA. Oxygen consumption of chondrocytes in agarose and collagen gels: a comparative analysis. Biomaterials. 2008;29:1484-1493.
4. Zeit, M, Ruiz-Torres A, Merker HJ. Collagen metabolism in granulating wounds of rat skin. Arch Dermatol Res. 1978;263:207-214. (Pubitemid 9051543)
5. Wu J, Reinhardt DP, Batmunkh C et al. Functional diversity of lysyl hydroxylase 2 in collagen synthesis of human dermal fibroblasts. Exp Cell Res. 2006;312:3485-3494. (Pubitemid 44470770)
6. Riches K, Morley ME, Turner NA et al. Chronic hypoxia inhibits MMP-2 activation and cellular invasion in human cardiac myofibroblasts. J Molec and Cell Cardiol. 2009;47:391-399.
7. Milovanova TN, Bhopale VM, Sorokina EM et al. Hyperbaric oxygen stimulates vasculogenic stem cell growth and differentiation in vivo. J Applied Physiol. 2009;106:711-728.
8. Kang TS, Gorti GK, Quan SY, Ho M, Koch RJ. Effect of hyperbaric oxygen on the growth factor profile of fibroblasts. Arch Facial Plast Surg. 2004;6:31-35.
9. Ruocco V, Bimonte D, Luongo C, Florio M. Hyperbaric oxygen treatment of toxic epidermal necrolysis. Cutis. 1986;38:267-271. (Pubitemid 16030537)
10. Melikian V, Laverson S, Zawacki B. Oxygen-derived free radical inhibition in the healing of experimental zone-of-stasis burns. J Trauma. 1987;27:151-154. (Pubitemid 17055748)
11. Doillon CJ, Silver FH. Collagen-based wound dressing: effects of hyaluronic acid and fibronectin on wound healing. Biomaterials. 1986;7:3-8. (Pubitemid 16151607)
12. Park MK, Myers RA, Marzella L. Oxygen tensions and infections: modulation of microbial growth, activity of antimicrobial agents, and immunologic responses. Clin Infect Dis. 1992;14:720-740.
13. Bugge DM, Hegaret H, Wikfors GH, Allam B. Oxidative burst in hard clam (Mercenaria mercenaria) haemocytes. Fish Shellfish Immunol. 2006;23:188-96.
14. Battistoni A, Ajello M, Ammendola S, Superti F, Rotilio G, Valenti P. Involvement of reactive oxygen species in bacterial killing within epithelial cells. Int J Immunopathol Pharmacol. 2004;17:71-76. (Pubitemid 39572190)
15. Dwyer DJ, Kohanski MA, Collins JJ. Role of reactive oxygen species in antibiotic action and resistance. Curr Opinion in Microbiol. 2009;12:482-489.
16. Cimsit M, Uzun G, Yildiz S. Hyperbaric oxygen therapy as an anti-infective agent. Expert Rev Anti Infect Ther. 2009;7:1015-1026.
17. Conconi MT, Baiguera S, Guidolin D et al. Effects of hyperbaric oxygen on proliferative and apoptotic activities and reactive oxygen species generation in mouse fibroblast 3T3/J2 cell line. J Investig Med. 2003;51:227-232. (Pubitemid 36870446)
18. Tompach PC, Lew D, Stoll JL. Cell response to hyperbaric oxygen treatment. Int J Oral Maxillofac Surg. 1997;26:82-86. (Pubitemid 127357220)
19. Diehr, S, Hamp A, Jamieson B, Mendoza M. Do topical antibiotics improve wound healing? J Fam Pract. 2007;56:140-144.
20. Leaper DJ. Silver dressings: their role in wound management. Int Wound J. 2006;3:282-294.
21. Dinh TL, Veves A. Treatment of diabetic ulcers. Dermatol Ther. 2006;19:348-355. (Pubitemid 44951040)
22. Thackham JA, McElwain DL, Long RJ. The use of hyperbaric oxygen therapy to treat chronic wounds: A review. Wound Repair Regen. 2008;16:321-330. (Pubitemid 351661571)
23. Kabon B, Rozum R, Marschalek C et al. Supplemental postoperative oxygen and tissue oxygen tension in morbidly obese patients. Obes Surg. 20:885-894.
24. Doillon CJ, Dunn MG, Berg RA, Silver FH. Collagen deposition during wound repair. Scan Electron Microsc. 1985;897-903. (Pubitemid 15002955)
25. Paternostro C, David E, Novo E, Parola M. Hypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases. World J Gastroenterol. 16:281-288.
26. Dong H, Wang Q, Zhang Y, Jiang B, Xu X, Zhang Z. Angiogenesis induced by hVEGF165 gene controlled by hypoxic response elements in rabbit ischemia myocardium. Exp Biol Med (Maywood). 2009;234:1417-1424.
27. Jeon O, Kang SW, Lim HW, Hyung Chung J, Kim BS. Long-term and zero-order release of basic fibroblast growth factor from heparin-conjugated poly (L-lactide-co-glycolide) nanospheres and fibrin gel. Biomaterials. 2006;27:1598-1607. (Pubitemid 41739585)
28. Bardoel JW, Stadelmann WK, Tobin GR et al. Use of the rectus abdominis muscle for abdominal stoma sphincter construction: an anatomical feasibility study. Plast Reconstr Surg. 2000;105:589-595. (Pubitemid 30110995)
29. McLachlan EM. Diversity of sympathetic vasoconstrictor pathways and their plasticity after spinal cord injury. Clin Auton Res. 2007;17:6-12.
30. Kawase T, Okuda K, Wolff LF, Yoshie H. Platelet-rich plasma-derived fibrin clot formation stimulates collagen synthesis in periodontal ligament and osteoblastic cells in vitro. J Periodontol. 2003;74:858-864. (Pubitemid 36874119)
31. Rughetti A, Giusti I, D'Ascenzo S et al. Platelet gelreleased supernatant modulates the angiogenic capability of human endothelial cells. Blood Transfus. 2008;6:12-17. (Pubitemid 352025972)
32. Creaney L, Hamilton B. Growth factor delivery methods in the management of sports injuries: the state of play. British Journal of Sports Medicine. 2008;42:314-320. (Pubitemid 351702675)
33. Wrotniak M, Bielecki T, Gazdzik TS. Current opinion about using the platelet-rich gel in orthopaedics and trauma surgery. Ortop Traumatol Rehabil. 2007;9:227-238. (Pubitemid 47523218)
34. Berg C, Hammarstrom S, Herbertsson H et al. Plateletinduced growth of human fibroblasts is associated with an increased expression of 5-lipoxygenase. Thromb Haemost. 2006;96:652-659. (Pubitemid 44782546)
35. Golz G, Uhlmann L, Ludecke D, Markgraf N, Nitsch R, Hendrix S. The cytokine/neurotrophin axis in peripheral axon outgrowth. Eur J Neurosci. 2006;24:2721-2730. (Pubitemid 44813823)
36. Wei X, Zhang J, Zhuang X. [The correlation of PDGF and TNF-alpha and HA and nasal mucosa healing after ESS]. Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2006;20:771-773.
37. Delavary BM, van der Veer WM, van Egmond M, Niessen FB, Beelen RH. Macrophages in skin injury and repair. Immunobiology.
38. Soomekh DJ. Current concepts for the use of platelet-rich plasma in the foot and ankle. Clin Podiatr Med Surg. 28:155-170.
39. Patel GK. The role of nutrition in the management of lower extremity wounds. Int J Low Extrem Wounds. 2005;4:12-22. (Pubitemid 41435503)
40. Russell L. The importance of patients' nutritional status in wound healing. Br J Nurs. 2001;10:S42, S44-49.
41. Langkamp-Henken B, Hudgens J, Stechmiller JK, Herrlinger-Garcia KA. Mini nutritional assessment and screening scores are associated with nutritional indicators in elderly people with pressure ulcers. J Am Diet Assoc. 2005;105:1590-1596. (Pubitemid 41393041)
42. Halligan TJ, Russell NG, Dunn WJ, Caldroney SJ, Skelton TB. Identification and treatment of scurvy: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100:688-692. (Pubitemid 41666944)
43. Lansdown AB, Sampson B, Rowe A. Experimental observations in the rat on the influence of cadmium on skin wound repair. Int J Exp Pathol. 2001;82:35-41. (Pubitemid 32578835)
44. Declair V. The usefulness of topical application of essential fatty acids (EFA) to prevent pressure ulcers. Ostomy Wound Manage. 1997;43:48-52.
45. Daousi C, Benbow SJ, MacFarlane IA. Electrical spinal cord stimulation in the long-term treatment of chronic painful diabetic neuropathy. Diabet Med. 2005;22:393-398. (Pubitemid 40516236)
46. Flegg JA, Byrne HM, McElwain DL. Mathematical model of hyperbaric oxygen therapy applied to chronic diabetic wounds. Bull Math Biol. 72:1867-1891.
47. Lazarus GS, Cooper DM, Knighton DR et al. Definitions and guidelines for assessment of wounds and evaluation of healing. Arch Dermatol. 1994;130:489-493. (Pubitemid 24123372)
48. Boerema I. Hyperbaric oxygenation: The large chamber. Ann N Y Acad Sci. 1965;117:883-890.
49. Boerema I. The use of hyperbaric oxygen. Am Heart J. 1965;69:289-292.
50. Brummelkamp WH. [Treatment of infections due to anaerobic germs by inhalation of hyperbaric oxygen]. Ann Chir Thorac Cardiovasc. 1966;5:607-610.
51. Boerema I, Meyne NG, Brummelkamp WH et al. [Life without blood.]. Ned Tijdschr Geneeskd. 1960;104:949-954.
52. Gajendrareddy PK, Sen CK, Horan MP, Marucha PT. Hyperbaric oxygen therapy ameliorates stress-impaired dermal wound healing. Brain, Behavior, and Immunity. 2005;19:217-222. (Pubitemid 40431536)
53. Eming SA, Brachvogel B, Odorisio T, Koch M. Regulation of angiogenesis: wound healing as a model. Progress in Histochem and Cytochem. 2007;42:115-170. (Pubitemid 350016248)
54. Agostoni P, Caldara G, Bussotti M et al. Continuous positive airway pressure increases haemoglobin O2 saturation after acute but not prolonged altitude exposure. Europ Heart J. 2009. 31:457-63
55. Gray A, Goodacre S, Newby DE, Masson M, Sampson F, Nicholl J. Noninvasive ventilation in acute cardiogenic pulmonary edema. New England J Med. 2008;359:142-151. (Pubitemid 351962037)
56. Whitney JD. The influence of tissue oxygen and perfusion on wound healing. AACN Clin Issues in Crit Care Nursing. 1990;1:578-584.
57. Eschenfelder CC, Krug R, Yusofi AF et al. Neuroprotection by oxygen in acute transient focal cerebral ischemia is dose dependent and shows superiority of hyperbaric oxygenation. Cerebrovasc Dis. 2008;25:193-201. (Pubitemid 351450421)
58. Liu Y, Cox SR, Morita T, Kourembanas S. Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer. Circ Res. 1995;77:638-643.
59. Lee CC, Chen SC, Tsai SC et al. Hyperbaric oxygen induces VEGF expression through ERK, JNK and c-Jun/AP-1 activation in human umbilical vein endothelial cells. J Biomed Sci. 2006;13:143-156.
60. Bayati S, Russell RC, Roth AC. Stimulation of angiogenesis to improve the viability of prefabricated flaps. Plast Reconstr Surg. 1998;101:1290-1295. (Pubitemid 28152705)
61. Mychaskiw G, 2nd, Pan J, Shah S et al. Effects of hyperbaric oxygen on skin blood flow and tissue morphology following sciatic nerve constriction. Pain Physician. 2005;8:157-161. (Pubitemid 40691826)
62. Davis JC, Dunn JM, Heimbach RD. Indications for hyperbaric oxygen therapy. Tex Med. 1980;76:44-47.
63. Bouachou, G, Cronier P, Gouello JP, Toulemonde JL, Talha A, Alquier P. Hyperbaric oxygen therapy in the management of crush injuries: a randomized double-blind placebo-controlled clinical trial. J Trauma. 1996;41:333-339. (Pubitemid 26271820)
64. Lebel D, Gortzak Y, Nyska M, Katz T, Atar D, Etzion Y. [Hyperbaric oxygen therapy for chronic diabetic wounds of the lower limbs-a review of the literature]. Harefuah. 2007;146:223-227.
65. Milerad J. Effects of theophylline on ventilatory response to hypoxic challenge. Arch of Disease in Childhood. 1987;62:1242-1246. (Pubitemid 18050230)
66. Grolman RE, Wilkerson DK, Taylor J, Allinson P, Zatina MA. Transcutaneous oxygen measurements predict a beneficial response to hyperbaric oxygen therapy in patients with nonhealing wounds and critical limb ischemia. Am Surg. 2011;67;1072-9; discussion 1080.
67. Boykin JV, Jr., Crossland MC, Cole LM. Wound healing management: enhancing patient outcomes and reducing costs. J Healthcare Resource Manag. 1997;15:22, 24-26.
68. Langham MC, Magland JF, Epstein CL, Floyd TF, Wehrli FW. Accuracy and precision of MR blood oximetry based on the long paramagnetic cylinder approximation of large vessels. Magn Reson Med. 2009;62:333-340.
69. Wolf U, Scholkmann F, Rosenberger R, Wolf M, Nelle M. Changes in hemodynamics and tissue oxygenation saturation in the brain and skeletal muscle induced by speech therapy - a near-infrared spectroscopy study. Sci World J. 2011;11:1206-1215.
70. Akiyama T, Ohira T, Kawase T, Kato T. TMS orientation for NIRS-functional motor mapping. Brain Topogr. 2006;19:1-9. (Pubitemid 44924067)
71. Omur-Ozbek P, Dietrich AM. Retronasal perception and flavour thresholds of iron and copper in drinking water. J Water Health 2011;9:1-9
72. Omur-Ozbek P, Gallagher DL, Dietrich AM. Determining human exposure and sensory detection of odorous compounds released during showering. Environ Sci Technol. 2011;45:468-473.
73. Cronje FJ. Oxygen therapy and wound healing - topical oxygen is not hyperbaric oxygen therapy. S Afr Med J. 2005;95:840. (Pubitemid 41684069)
74. Gordillo GM, Schlanger R, Wallace WA, Bergdall V, Bartlett R, Sen CK. Protocols for topical and systemic oxygen treatments in wound healing. Methods Enzymol. 2004;381:575-585. (Pubitemid 38401532)
75. Burghart K. The topical hyperbaric oxygen therapy debate. Ostomy Wound Manage. 2003;49:8; author reply 8.
76. Lipsky BA, Berendt AR, Deery HG et al. Diagnosis and treatment of diabetic foot infections. Plast Reconstr Surg. 2006;117:212S-238S. (Pubitemid 44334747)
77. Kalliainen LK, Gordillo GM, Schlanger R, Sen CK. Topical oxygen as an adjunct to wound healing: a clinical case series. Pathophysiol. 2003;9:81-87. (Pubitemid 37297329)
78. Feldmeier JJ, Hopf HW, Warriner RA, 3rd, Fife CE, Gesell LB, Bennett M. UHMS position statement: topical oxygen for chronic wounds. Undersea Hyperb Med. 2005;32:157-168. (Pubitemid 41003495)
79. Sander AL, Henrich D, Muth CM, Marzi I, Barker JH, Frank JM. In vivo effect of hyperbaric oxygen on wound angiogenesis and epithelization. Wound Repair and Regen. 2009;17:179-184.
80. Friedman HI, Fitzmaurice M, Lefaivre JF, Vecchiolla T, Clarke D. An evidence-based appraisal of the use of hyperbaric oxygen on flaps and grafts. Plast Reconstr Surg. 2006;117:175S-190S; discussion 191S-192S. (Pubitemid 44317783)
81. Kaid, CG, Khandelwal S. Hyperbaric oxygen: applications in infectious disease. Emerg Med Clinics of North America. 2008;26:571-595. (Pubitemid 351491562)
82. Kuffler DP. The role of hyperbaric oxygen therapy in enhancing the rate of wound healing with a focus on axon regeneration. PR Health Sci J. 2011;30:35-42.
83. Rockswold SB, Rockswold GL, Defillo A. Hyperbaric oxygen in traumatic brain injury. Neurol Res. 2007;29:162-172. (Pubitemid 46685269)
84. Allen BW, Demchenko IT, Piantadosi CA. Two faces of nitric oxide: implications for cellular mechanisms of oxygen toxicity. J Applied Physiol. 2009;106:662-667.
85. Mendis E, Kim MM, Rajapakse N, Kim SK. Sulfated glucosamine inhibits oxidation of biomolecules in cells via a mechanism involving intracellular free radical scavenging. Europ. J Pharmacol. 2008;579:74-85.
86. Berendt AR. Counterpoint: hyperbaric oxygen for diabetic foot wounds is not effective. Clin Infect Dis. 2006;43:193-198.
87. Al-Waili NS, Butler GJ, Beale J et al. Influences of hyperbaric oxygen on blood pressure, heart rate and blood glucose levels in patients with diabetes mellitus and hypertension. Arch Med Res. 2006;37:991-997. (Pubitemid 44540236)
88. Phillips JC. Understanding hyperbaric oxygen therapy and its use in the treatment of compromised skin grafts and flaps. Plast Surg Nurs. 2005;25:72-80; quiz 81-72.
89. Ren P, Kang Z, Gu G et al. Hyperbaric oxygen preconditioning promotes angiogenesis in rat liver after partial hepatectomy. Life Sciences. 2008;83:236-241.
90. Moutschen, MP, Scheen AJ, Lefebvre PJ. Impaired immune responses in diabetes mellitus: analysis of the factors and mechanisms involved. Relevance to the increased susceptibility of diabetic patients to specific infections. Diabete Metab. 1992;18:187-201.
91. Wieman TJ, Mercke YK, Cerrito PB, Taber SW. Resection of the metatarsal head for diabetic foot ulcers. Am J Surg. 1998;176:436-441. (Pubitemid 29021543)
92. Lyon KC. The case for evidence in wound care: investigating advanced treatment modalities in healing chronic diabetic lower extremity wounds. Journal of Wound, Ostomy and Continence Nursing. 2008;35:585-590.
93. Ong M. Hyperbaric oxygen therapy in the management of diabetic lower limb wounds. Singapore Med Journal. 2008;49:105-109. (Pubitemid 351488544)
94. Corbucci GG, Perrino C, Donato G et al. Transient and reversible deoxyribonucleic acid damage in human left ventricle under controlled ischemia and reperfusion. J Am Col Cardiol. 2004;43:1992-1999. (Pubitemid 38686792)
95. Zamboni WA, Browder LK, Martinez J. Hyperbaric oxygen and wound healing. Clin Plast Surg. 2003;30:67-75. (Pubitemid 36288302)
96. Moali C, Hulmes DJ. Extracellular and cell surface proteases in wound healing: new players are still emerging. Eur J Dermatol. 2009;19:552-564
97. Li J, Chen J, Kirsner R. Pathophysiology of acute wound healing. Clin Dermatol. 2007;25:9-18. (Pubitemid 46177460)
98. Madden JW, Peacock EE, Jr. Studies on the biology of collagen during wound healing. I. Rate of collagen synthesis and deposition in cutaneous wounds of the rat. Surgery. 1968;64:288-294.
99. DelBalso AM, Adrian JC. Collagen gel in osseous defects. A preliminary study. Oral Surg Oral Med Oral Pathol. 1976;42:562-569.
100. Bishop A. Role of oxygen in wound healing. J Wound Care. 2008;17:399-402.
101. Rodriguez, PG, Felix FN, Woodley DT, Shim EK. The role of oxygen in wound healing: a review of the literature. Dermatol Surgery. 2008;34:1159-1169.
102. Thackham JA, McElwain DL, Long RJ. The use of hyperbaric oxygen therapy to treat chronic wounds: A review. Wound Repair Regen. 2008;16:321-330. (Pubitemid 351661571)
103. Parsons KK, Maeda N, Yamauchi M, Banes AJ, Koller BH. Ascorbic acid-independent synthesis of collagen in mice. Am J Physiol Endocrinol Metab. 2006;290:E1131-1139. (Pubitemid 43847896)
104. Roberts GP, Harding KG. Stimulation of glycosaminoglycan synthesis in cultured fibroblasts by hyperbaric oxygen. Brit J Dermatol. 1994;131:630-633. (Pubitemid 24344046)
105. Mariggio MA, Cassano A, Vinella A et al. Enhancement of fibroblast proliferation, collagen biosynthesis and production of growth factors as a result of combining sodium hyaluronate and aminoacids. Int J Immunopathol Pharmacol. 2009;22:485-492.
106. Norstrom A. Acute effects of prostaglandins on the biosynthesis of connective tissue constituents in the non-pregnant human cervix uteri. Acta Obstet Gynecol Scand. 1984;63:169-173. (Pubitemid 14130521)
107. Alvarez RH, Kantarjian HM, Cortes JE. Biology of platelet-derived growth factor and its involvement in disease. Mayo Clin Proc. 2006;81:1241-1257. (Pubitemid 44316290)
108. Arii S, Teramoto K, Kawamura T. Current progress in the understanding of and therapeutic strategies for ischemia and reperfusion injury of the liver. J Hepatobiliary Pancreat Surg. 2003;10:189-194. (Pubitemid 37407502)
109. Halbertsma FJ, Vaneker M, Scheffer GJ, van der Hoeven JG. Cytokines and biotrauma in ventilator-induced lung injury: a critical review of the literature. Neth J Med. 2005;63:382-392. (Pubitemid 41723236)
110. Colic M, Gazivoda D, Vucevic D et al. Regulatory T-cells in periapical lesions. J Dent Res. 2009;88:997-1002.
111. Stadelmann WK, Digenis AG, Tobin GR. Physiology and healing dynamics of chronic cutaneous wounds. Am J Surg. 1998;176:26S-38S. (Pubitemid 28460655)
112. Raud J. Vasodilatation and inhibition of mediator release represent two distinct mechanisms for prostaglandin modulation of acute mast cell-dependent infammation. Br J Pharmacol. 1990;99:449-454. (Pubitemid 20069143)
113. Komoriya K, Ohmori H, Azuma A et al. Prostaglandin I2 as a potentiator of acute inflammation in rats. Prostaglandins. 1978;15:557-564. (Pubitemid 8333957)
114. Brain SD, Williams TJ. Inflammatory oedema induced by synergism between calcitonin gene-related peptide (CGRP) and mediators of increased vascular permeability. Br J Pharmacol. 1985;86:855-860. (Pubitemid 16211362)
115. Hirasawa N, Ohuchi K, Sugio K, Tsurufuji S, Watanabe M, Yoshino S. Vascular permeability responses and the role of prostaglandin E2 in an experimental allergic inflammation of air pouch type in rats. Br J Pharmacol. 1986;87:751-756. (Pubitemid 16047539)
116. Omata M, Watanabe M, Hirasawa N, Tsurufuji S, Mue S, Ohuchi K. A role of peripheral leukocytes in vascular permeability and edema formation in air pouch type allergic inflammation in rats. J Pharmacobiodyn. 1991;14:267-275.
117. Romanovsky AA, Almeida MC, Aronoff DM et al. Feverand hypothermia in systemic inflammation: recent discoveries and revisions. Front Biosci. 2005;10:2193-2216. (Pubitemid 40905292)
118. Rittner HL, Machelska H, Stein C. Leukocytes in the regulation of pain and analgesia. J Leukoc Biol. 2005;78:1215-1222. (Pubitemid 41779227)
119. Schaible HG, Ebersberger A, Von Banchet GS. Mechanisms of pain in arthritis. Ann N Y Acad Sci. 2002;966:343-354. (Pubitemid 34729193)
120. Cukjati D, Rebersek S, Karba R, Miklavcic D. Modelling of chronic wound healing dynamics. Med Biol Eng Comput. 2000;38:339-347. (Pubitemid 30352932)
121. Al-Waili NS, Butler GJ. Effects of hyperbaric oxygen on inflammatory response to wound and trauma: possible mechanism of action. ScientificWorldJournal. 2006;6:425-441.
122. Vilela DS, Lazarini PR, Da Silva CF. Effects of hyperbaric oxygen therapy on facial nerve regeneration. Acta Otolaryngol. 2008;128:1048-1052.
123. Muller A, Tal R, Donohue JF et al. The effect of hyperbaric oxygen therapy on erectile function recovery in a rat cavernous nerve injury model. J Sex Med. 2008;5:562-570. (Pubitemid 351337882)
124. Bajrovic FF, Sketelj J, Jug M, Gril I, Mekjavic IB. The effect of hyperbaric oxygen treatment on early regeneration of sensory axons after nerve crush in the rat. J Peripher Nerv Syst. 2002;7:141-148.
125. Santos PM. A functional model system of an hypoxic nerve injury and its evaluation. Laryngoscope. 2000;110:845-853. (Pubitemid 30266267)
126. Eguiluz-Ordonez R, Sanchez CE, Venegas A, Figueroa-Granados V, Hernandez-Pando R. Effects of hyperbaric oxygen on peripheral nerves. Plast Reconstr Surg. 2006;118:350-357; discussion 358-359. (Pubitemid 44162038)
127. Haapaniemi T, Nishiura Y, Dahlin LB. Effects of hyperbaric oxygen treatment on axonal outgrowth in sciatic nerve grafts in rats. Scand J Plast Reconstr Surg Hand Surg. 2001;35:7-11. (Pubitemid 32222645)
128. Nishiura Y, Haapaniemi T, Dahlin LB. Hyperbaric oxygen treatment has different effects on nerve regeneration in acellular nerve and muscle grafts. J Peripher Nerv Syst. 2001;6:73-78. (Pubitemid 32606887)
129. Zamboni WA, Brown RE, Roth AC, Mathur A, Stephenson LL. Functional evaluation of peripheral-nerve repair and the effect of hyperbaric oxygen. J Reconstr Microsurg. 1995;11:27-29; discussion 29-30.
130. Haapaniemi T, Nishiura Y, Dahlin LB. Functional evaluation after rat sciatic nerve injury followed by hyperbaric oxygen treatment. J Peripher Nerv Syst. 2002;7:149-154.
131. Nakajima M, Kuwabara S, Uchino F, Hirayama K. [Enhanced regeneration of terminal axons after hyperbaric oxygen therapy in a patient resembling progressive postpoliomyelitis muscular atrophy]. Rinsho Shinkeigaku. 1994;34:48-51. (Pubitemid 24135382)
132. Zhao DW. [Therapeutic effect of hyperbaric oxygen on recovery of surgically repaired peripheral nerve injury]. Zhonghua Wai Ke Za Zhi. 1991;29:118-120, 143.
133. Bajrovic FF, Sketelj J, Jug M, Gril I, Mekjavic IB. The effect of hyperbaric oxygen treatment on early regeneration of sensory axons after nerve crush in the rat. J Peripher Nerv Syst. 2002;7:141-148.
134. Haapaniemi T, Nylander G, Kanje M, Dahlin L. Hyperbaric oxygen treatment enhances regeneration of the rat sciatic nerve. Exp Neurol. 1998;149:433-438. (Pubitemid 28115081)
135. Nishiura Y, Haapaniemi T, Dahlin LB. Hyperbaric oxygen treatment has different effects on nerve regeneration in acellular nerve and muscle grafts. J Peripher Nerv Syst. 2001;6:73-78. (Pubitemid 32606887)
136. Eguiluz-Ordonez R, Sanchez CE, Venegas A, Figueroa-Granados V, Hernandez-Pando R. Effects of hyperbaric oxygen on peripheral nerves. Plast Reconstr Surg. 2006;118:350-357; discussion 358-359. (Pubitemid 44162038)
137. Bradshaw PO, Nelson AG, Fanton JW, Yates T, Kagan-Hallet KS. Effect of hyperbaric oxygenation on peripheral nerve regeneration in adult male rabbits. Undersea Hyperb Med. 1996;23:107-113. (Pubitemid 126499590)
138. Sanchez EC. Hyperbaric oxygenation in peripheral nerve repair and regeneration. Neurological Research. 2007;29:184-198. (Pubitemid 46685271)
139. Al-Waili NS, Butler GJ, Beale J et al. Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease. Adv Ther. 2005;22:659-678.
140. Al-Waili NS, Butler GJ, Beale J et al. Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease. Advances in Therapy. 2005;22:659-678.
141. Al-Waili NS, Butler GJ, Beale J et al. Hyperbaric oxygen and malignancies: a potential role in radiotherapy, chemotherapy, tumor surgery and phototherapy. Med Sci Monit. 2005;11:RA279-289. (Pubitemid 41330141)
142. Rossignol DA. Hyperbaric oxygen therapy might improve certain pathophysiological findings in autism. Med Hypotheses. 2007;68:1208-1227. (Pubitemid 46498438)
143. Al-Waili NS, Butler GJ, Petrillo RL, Carrey Z, Hamilton RW. Hyperbaric oxygen and lymphoid system function: a review supporting possible intervention in tissue transplantation. Technol Health Care. 2006;14:489-498. (Pubitemid 44885293)
144. Vlodavsky E, Palzur E, Soustiel JF. Hyperbaric oxygen therapy reduces neuroinflammation and expression of matrix metalloproteinase-9 in the rat model of traumatic brain injury. Neuropathol Appl Neurobiol. 2006;32:40-50.
145. Montgomery D, Goldberg J, Amar M et al. Effects of hyperbaric oxygen therapy on children with spastic diplegic cerebral palsy: a pilot project. Undersea Hyperb Med. 1999;26:235-242.
146. Harch PG, Kriedt C, Van Meter KW, Sutherland RJ. Hyperbaric oxygen therapy improves spatial learning and memory in a rat model of chronic traumatic brain injury. Brain Res. 2007;1174:120-129. (Pubitemid 47454729)
147. Baugh MA. HIV: reactive oxygen species, enveloped viruses and hyperbaric oxygen. Med Hypotheses. 2000;55:232-238.
148. Edwards ML. Hyperbaric oxygen therapy. Part 2: application in disease. J Vet Emerg Crit Care (San Antonio). 20:289-297.
149. Marcon RM, Cristante AF, de Barros Filho TE, de Oliveira RP, dos Santos GB. Potentializing the effects of GM1 by hyperbaric oxygen therapy in acute experimental spinal cord lesion in rats. Spinal Cord. 48:808-813.
150. Topuz K, Colak A, Cemil B et al. Combined hyperbaric oxygen and hypothermia treatment on oxidative stress parameters after spinal cord injury: an experimental study. Arch Med Res. 41:506-512.
151. Kahraman S, Duz B, Kayali H et al. Effects of methylprednisolone and hyperbaric oxygen on oxidative status after experimental spinal cord injury: a comparative study in rats. Neurochem Res. 2007;32:1547-1551. (Pubitemid 47094416)
152. Dave KR, Prado R, Busto R et al. Hyperbaric oxygen therapy protects against mitochondrial dysfunction and delays onset of motor neuron disease in Wobbler mice. Neuroscience. 2003;120:113-120. (Pubitemid 36782636)
153. Steele J, Matos LA, Lopez EA et al. Phase I safety study of hyperbaric oxygen therapy for amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord. 2004;5:250-254. (Pubitemid 40125194)
154. Yin D, Zhou C, Kusaka I et al. Inhibition of apoptosis by hyperbaric oxygen in a rat focal cerebral ischemic model. J Cereb Blood Flow Metab. 2003;23:855-864. (Pubitemid 36818693)
155. Wada K, Nishi D, Kitamura T et al. Hyperbaric oxygenation therapy enhances the protective effect of moderate hypothermia against forebrain ischemia in the gerbil hippocampus. Undersea Hyperb Med. 2006;33:399-405.
156. Calvert JW, Yin W, Patel M et al. Hyperbaric oxygenation prevented brain injury induced by hypoxia-ischemia in a neonatal rat model. Brain Res. 2002;951:1-8. (Pubitemid 35253890)
157. Chuba PJ, Aronin P, Bhambhani K et al. Hyperbaric oxygen therapy for radiation-induced brain injury in children. Cancer. 1997;80:2005-2012. (Pubitemid 27479797)
158. Bui QC, Lieber M, Withers HR, Corson K, van Rijnsoever M, Elsaleh H. The efficacy of hyperbaric oxygen therapy in the treatment of radiation-induced late side effects. Int J Radiat Oncol Biol Phys. 2004;60:871-878. (Pubitemid 39311768)
159. Yin D, Zhang JH. Delayed and multiple hyperbaric oxygen treatments expand therapeutic window in rat focal cerebral ischemic model. Neurocrit Care. 2005;2:206-211. (Pubitemid 41270868)
160. Van der Heide SJ, Seamon JP. Resolution of delayed altered mental status associated with hydrogen peroxide ingestion following hyperbaric oxygen therapy. Academic Emergency Medicine. 2003;10:998-1000. (Pubitemid 37093205)
161. Clifton GL. Hypothermia and hyperbaric oxygen as treatment modalities for severe head injury. New Horizons. 1995;3:474-478.
162. Iwatsuki N, Takahashi M, Ono K, Tajima T. Hyperbaric oxygen combined with nicardipine administration accelerates neurologic recovery after cerebral ischemia in a canine model. Critical Care Med. 1994;22:858-863. (Pubitemid 24151082)
163. Palzur E, Zaaroor M, Vlodavsky E, Milman F, Soustiel JF. Neuroprotective effect of hyperbaric oxygen therapy in brain injury is mediated by preservation of mitochondrial membrane properties. Brain Res. 2008;1221:126-133.
164. Nakajima M, Kuwabara S, Uchino F, Hirayama K. [Enhanced regeneration of terminal axons after hyperbaric oxygen therapy in a patient resembling progressive postpoliomyelitis muscular atrophy]. Rinsho Shinkeigaku Clinical Neurology. 1994;34:48-51. (Pubitemid 24135382)
165. Zamboni WA, Brown RE, Roth AC, Mathur A, Stephenson LL. Functional evaluation of peripheral-nerve repair and the effect of hyperbaric oxygen. J Reconstr Microsurg. 1995;11:27-29; discussion 29-30.
166. Budic I, Pavlovic D, Cvetkovic T et al. The effects of different anesthesia techniques on free radical production after tourniquet-induced ischemia-reperfusion injury at children's age. Vojnosanit Pregl. 67:659-664.
167. Kawamura N, Schmelzer JD, Wang Y, Schmeichel AM, Low PA. The therapeutic window of hypothermic neuroprotection in experimental ischemic neuropathy: protection in ischemic phase and potential deterioration in later reperfusion phase. Exp Neurol. 2005;195:305-312. (Pubitemid 41297783)
168. Prpa B, Huddleston PM, An KN, Wood MB. Revascularization of nerve grafts: a qualitative and quantitative study of the soft-tissue bed contributions to blood flow in canine nerve grafts. J Hand Surg Am. 2002;27:1041-1047. (Pubitemid 35439774)
169. Colen KL, Choi M, Chiu DT. Nerve grafts and conduits. Plast Reconstr Surg. 2009;124:e386-394.
170. Ostrowski RP, Graupner G, Titova E et al. The hyperbaric oxygen preconditioning-induced brain protection is mediated by a reduction of early apoptosis after transient global cerebral ischemia. Neurobiol of Disease. 2008;29:1-13. (Pubitemid 350180478)
171. Wood MD, Macewan MR, French AR et al. Fibrin matrices with affinity-based delivery systems and neurotrophic factors promote functional nerve regeneration. Biotechnol and Bioengineering. 106:970-979.
172. Gordon T. The physiology of neural injury and regeneration: The role of neurotrophic factors. J Commun Disorders. 43:265-273.
173. Gordon T, Chan KM, Sulaiman OA, Udina E, Amirjani N, Brushart TM. Accelerating axon growth to overcome limitations in functional recovery after peripheral nerve injury. J Neurosurg 2009;65:A132-44.
174. Chu TH, Li SY, Guo A, Wong WM, Yuan Q, Wu W. Implantation of neurotrophic factor-treated sensory nerve graft enhances survival and axonal regeneration of motoneurons after spinal root avulsion. Journal of Neuropathology and Exp Neurol. 2009;68:94-101.
175. Michalski B, Bain JR, M Fahnestock. Long-term changes in neurotrophic factor expression in distal nerve stump following denervation and reinnervation with motor or sensory nerve. J Neurochem. 2008;105:1244-1252. (Pubitemid 351590787)
176. Yu Y, Matsuyama Y, Yanase M et al. Effects of hyperbaric oxygen on GDNF expression and apoptosis in spinal cord injury. Neuroreport. 2004;15:2369-2373. (Pubitemid 39488922)
177. Tai PA, Chang CK, Niu KC, Lin MT, Chiu WT, Lin CM. Attenuating experimental spinal cord injury by hyperbaric oxygen: stimulating production of vasculoendothelial and glial cell line-derived neurotrophic growth factors and interleukin-10. J Neurotrauma. 27:1121-1127.
178. Asano T, Kaneko E, Shinozaki S et al. Hyperbaric oxygen induces basic fibroblast growth factor and hepatocyte growth factor expression, and enhances blood perfusion and muscle regeneration in mouse ischemic hind limbs. Circ J. 2007;71:405-411. (Pubitemid 46409546)
179. Thornton MR, Shawcross SG, Mantovani C, Kingham PJ, Birchall MA, Terenghi G. Neurotrophins 3 and 4 differentially regulate NCAM, L1 and N-cadherin expression during peripheral nerve regeneration. Biotechnol and Applied Biochem. 2008;49:165-174. (Pubitemid 351271081)
180. Fu C, Hong G, Wang F. Favorable effect of local VEGF gene injection on axonal regeneration in the rat sciatic nerve. J Huazhong Univ Sci Technolog Med Sci. 2007;27:186-189.
181. Hobson MI, Green CJ, Terenghi G. VEGF enhances intraneural angiogenesis and improves nerve regeneration after axotomy. J Anat. 2000;197 Pt 4:591-605. (Pubitemid 32051540)
182. Atkins S, Loescher AR, Boissonade FM et al. Interleukin-10 reduces scarring and enhances regeneration at a site of sciatic nerve repair. J Periph Nerv System. 2007;12:269-276. (Pubitemid 350179484)
183. Zhao LL, Davidson JD, Wee SC, Roth SI, Mustoe TA. Effect of hyperbaric oxygen and growth factors on rabbit ear ischemic ulcers. Archives of Surg. 1994;129:1043-1049. (Pubitemid 24320797)
184. Gu GJ, Li YP, Peng ZY et al. Mechanism of ischemic tolerance induced by hyperbaric oxygen preconditioning XJ involves upregulation of hypoxia-inducible factor-1alpha and erythropoietin in rats. J Applied Physiol. 2008;104:1185-1191.
185. Lykissas MG, Korompilias AV, Vekris MD, Mitsionis GI, Sakellariou E, Beris AE. The role of erythropoietin in central and peripheral nerve injury. Clin Neurol Neurosurg. 2007;109:639-644. (Pubitemid 47248036)
186. McLeod M, Hong M, Mukhida K, Sadi D, Ulalia R, Mendez I. Erythropoietin and GDNF enhance ventral mesencephalic fiber outgrowth and capillary proliferation following neural transplantation in a rodent model of Parkinson's disease. Europ J Neurosci. 2006;24:361-370. (Pubitemid 44100328)
187. Lohmeyer JA, Essmann E, Richerson SJ et al. Use of Erythropoietin as adjuvant therapy in nerve reconstruction. Langenbecks Arch Surgery. 2008;393:317-323.
188. Gorio A, Gokmen N, Erbayraktar S et al. Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord trauma. Proceedings of the Nat Acad Sci United States of Am. 2002;99:9450-9455. (Pubitemid 34764634)
189. Vitellaro-Zuccarello L, Mazzetti S, Madaschi L, Bosisio P, Gorio A, De Biasi S. Erythropoietin-mediated preservation of the white matter in rat spinal cord injury. Neurosci. 2007;144:865-877. (Pubitemid 46013988)
190. Vitellaro-Zuccarello L, Mazzetti S, Madaschi L et al. Chronic erythropoietin-mediated effects on the expression of astrocyte markers in a rat model of contusive spinal cord injury. Neurosci. 2008;151:452-466.
191. Pan HC, Chin CS, Yang DY et al. Human amniotic fluid mesenchymal stem cells in combination with hyperbaric oxygen augment peripheral nerve regeneration. Neurochem Res. 2009;34:1304-1316.
192. Gorio A, Madaschi L, Di Stefano B et al. Methylprednisolone neutralizes the beneficial effects of erythropoietin in experimental spinal cord injury. Proc Nat Acad Sciences United States of Am. 2005;102:16379-16384. (Pubitemid 41688922)
193. Voigt C, Forschler A, Jaeger M, Meixensberger J, Kuppers-Tiedt L, Schuhmann MU. Protective effect of hyperbaric oxygen therapy on experimental brain contusions. Acta Neurochir Suppl. 2008;102:441-445.
194. McDonagh M, Helfand M, Carson S, Russman BS. Hyperbaric oxygen therapy for traumatic brain injury: a systematic review of the evidence. Archives of Physical Med and Rehabil. 2004;85:1198-1204. (Pubitemid 38962384)
195. Bennett MH, Trytko B, Jonker B. Hyperbaric oxygen therapy for the adjunctive treatment of traumatic brain injury. Cochrane Database Syst Rev. 2004; CD004609.
196. Wu J, Yang H, Qiu Z, Zhang Q, Ding T, Geng D. Effect of combined treatment with methylprednisolone and nogo-a monoclonal antibody after rat spinal cord injury. J Int Med Res. 38:570-582.
197. Sribnic, EA, Samantaray S, Das A et al. Postinjury estrogen treatment of chronic spinal cord injury improves locomotor function in rats. J Neurosci Res. 88:1738-1750.
198. Munts AG, van der Plas AA, Ferrari MD, Teepe-Twiss IM, Marinus J, van Hilten JJ. Efficacy and safety of a single intrathecal methylprednisolone bolus in chronic complex regional pain syndrome. Eur J Pain. 14:523-528.
199. Fumagalli F, Madaschi L, Brenna P et al. Single exposure to erythropoietin modulates Nerve Growth Factor expression in the spinal cord following traumatic injury: comparison with methylprednisolone. Eur J Pharmacol. 2008;578:19-27. (Pubitemid 350179757)
200. Guo Q, S Li, Liang Y, Zhang Y et al. Effects of C3 deficiency on inflammation and regeneration following spinal cord injury in mice. Neurosci Lett. 485:32-36.
201. Matchett GA, Martin RD, Zhang JH. Hyperbaric oxygen therapy and cerebral ischemia: neuroprotective mechanisms. Neurol Res. 2009;31:114-121.
202. Poli S, Veltkamp R. Oxygen therapy in acute ischemic stroke - experimental efficacy and molecular mechanisms. Curr Mol Med. 2009;9:227-241.
203. Veltkamp R, Warner DS, Domoki F et al. Hyperbaric oxygen decreases infarct size and behavioral deficit after transient focal cerebral ischemia in rats. Brain Res. 2000;853:68-73. (Pubitemid 30016000)
204. Konda A, Baba S, Iwaki T et al. Hyperbaric oxygenation prevents delayed neuronal death following transient ischaemia in the gerbil hippocampus. Neuropath and Applied Neurobiol. 1996;22:350-360. (Pubitemid 26278839)
205. Helms AK, Whelan HT, Torbey MT. Hyperbaric oxygen therapy of cerebral ischemia. Cerebrovascular Diseases. 2005;20:417-426. (Pubitemid 41675018)
206. Veltkamp R, Siebing DA, Heiland S et al. Hyperbaric oxygen induces rapid protection against focal cerebral ischemia. Brain Res. 2005;1037:134-138. (Pubitemid 40362389)
207. Chang CF, Niu KC, Hoffer BJ, Wang Y, Borlongan CV. Hyperbaric oxygen therapy for treatment of postischemic stroke in adult rats. Exp Neurol. 2000;166:298-306.
208. Takahashi M, Iwatsuki N, Ono K, Tajima T, Akama M, Koga Y. Hyperbaric oxygen therapy accelerates neurologic recovery after 15-minute complete global cerebral ischemia in dogs. Critical Care Med. 1992;20:1588-1594.
209. Xue L, Yu Q, Zhang H, Liu Y, Wang C, Wang Y. Effect of large dose hyperbaric oxygenation therapy on prognosis and oxidative stress of acute permanent cerebral ischemic stroke in rats. Neurol Res. 2008;30:389-393. (Pubitemid 351881292)
210. Bennett MH, Wasiak J, Schnabel A, Kranke P, French C. Hyperbaric oxygen therapy for acute ischaemic stroke. Cochrane Database Syst Rev. 2005; CD004954.
211. Veltkamp R, Siebing DA, Sun L et al. Hyperbaric oxygen reduces blood-brain barrier damage and edema after transient focal cerebral ischemia. Stroke. 2005;36:1679-1683. (Pubitemid 41098761)
212. Rusyniak DE, Kirk MA, May JD et al. Hyperbaric oxygen therapy in acute ischemic stroke: results of the Hyperbaric Oxygen in Acute Ischemic Stroke Trial Pilot Study. Stroke. 2003;34:571-574. (Pubitemid 36206367)
213. Anderson DC, Bottini AG, Jagiella WM et al. A pilot study of hyperbaric oxygen in the treatment of human stroke. Stroke. 1991;22:1137-1142.
214. Jadhav V, Ostrowski RP, Tong W, Matus B, Chang C, Zhang JH. Hyperbaric oxygen preconditioning reduces postoperative brain edema and improves neurological outcomes after surgical brain injury. Acta Neurochir Suppl. 106:217-220.
215. Yamashita S, Hirata T, Mizukami Y et al. Repeated preconditioning with hyperbaric oxygen induces neuroprotection against forebrain ischemia via suppression of p38 mitogen activated protein kinase. Brain Res. 2009;1301:171-179.
216. Wang L, Li W, Kang Z et al. Hyperbaric oxygen preconditioning attenuates early apoptosis after spinal cord ischemia in rats. J Neurotrauma. 2009;26:55-66.
217. Kretz A, Happold CJ, Marticke JK, Isenmann S. Erythropoietin promotes regeneration of adult CNS neurons via Jak2/Stat3 and PI3K/AKT pathway activation. Molec and Cell Neurosci. 2005;29:569-579. (Pubitemid 40984698)
218. Peng Z, Ren P, Kang Z et al. Up-regulated HIF-1alpha is involved in the hypoxic tolerance induced by hyperbaric oxygen preconditioning. Brain Res. 2008;1212:71-78.
219. Li JS, Zhang W, Kang ZM et al. Hyperbaric oxygen preconditioning reduces ischemia-reperfusion injury by inhibition of apoptosis via mitochondrial pathway in rat brain. Neurosci. 2009;159:1309-1315.
220. Xiong L, Zhu Z, Dong H, Hu W, Hou L, Chen S. Hyperbaric oxygen preconditioning induces neuroprotection against ischemia in transient not permanent middle cerebral artery occlusion rat model. Chinese Med J. 2000;113:836-839.
221. Dong H, Xiong L, Zhu Z, Chen S, Hou L, Sakabe T. Preconditioning with hyperbaric oxygen and hyperoxia induces tolerance against spinal cord ischemia in rabbits. Anesthesiol. 2002;96:907-912. (Pubitemid 34266684)
222. Li J, Liu W, Ding S et al. Hyperbaric oxygen preconditioning induces tolerance against brain ischemia-reperfusion injury by upregulation of antioxidant enzymes in rats. Brain Res. 2008;1210:223-229.
223. Li Z, Liu W, Kang Z et al. Mechanism of hyperbaric oxygen preconditioning in neonatal hypoxia-ischemia rat model. Brain Res. 2008;1196:151-156.
224. Yang ZJ, Xie Y, Bosco GM, Chen C, Camporesi EM. Hyperbaric oxygenation alleviates MCAO-induced brain injury and reduces hydroxyl radical formation and glutamate release. Eur J Applied Physiol and Occupatioal Physiol. 108:513-522.
225. Zhong Y, Yao H, Deng L, Cheng Y, Zhou X. Promotion of neurite outgrowth and protective effect of erythropoietin on the retinal neurons of rats. Graefes Arch for Clin and Exp Ophthal. 2007;245:1859-1867. (Pubitemid 350154022)
226. Wang R, Xu J, Xie J et al. Hyperbaric oxygen preconditioning promotes survival of retinal ganglion cells in a rat model of optic nerve crush. J Neurotrauma. 27:763-770.
227. Tai PA, Chang CK, Niu KC, Lin MT, Chiu WT. Lin, CM. Attenuating experimental spinal cord injury by hyperbaric oxygen: stimulating production of vasculoendothelial and glial cell line-derived neurotrophic growth factors and interleukin-10. J Neurotrauma. 2010;27:1121-1127.
228. Arato E, Kurthy M, Sinay L et al. Effect of vitamin E on reperfusion injuries during reconstructive vascular operations on lower limbs. Clinical Hemorheology and Microcirc. 44:125-136.
229. Lucius R, Mentlein R, Sievers J. Riboflavin-mediated axonal degeneration of postnatal retinal ganglion cells in vitro is related to the formation of free radicals. Free Radical Biol and Med. 1998;24:798-808. (Pubitemid 28169567)
230. Al Moutaery K, Arshaduddin M, Tariq M, Al Deeb S. Functional recovery and vitamin E level following sciatic nerve crush injury in normal and diabetic rats. Intl J Neurosc. 1998;96:245-254. (Pubitemid 128508361)
231. Cameron NE, Cotter MA. Metabolic and vascular factors in the pathogenesis of diabetic neuropathy. Diabetes. 1997;46 Suppl 2:S31-37. (Pubitemid 27377395)
232. Lucius R, Sievers J. Postnatal retinal ganglion cells in vitro: protection against reactive oxygen species (ROS)-induced axonal degeneration by cocultured astrocytes. Brain Res. 1996;743:56-62. (Pubitemid 27028756)
233. Cheng H, Fu YS, Guo JW. Ability of GDNF to diminish free radical production leads to protection against kainate-induced excitotoxicity in hippocampus. Hippocampus. 2004;14:77-86. (Pubitemid 38351174)
234. Lykissas MG, Sakellariou E, Vekris MD et al. Axonal regeneration stimulated by erythropoietin: an experimental study in rats. J Neurosci Methods. 2007;164:107-115. (Pubitemid 46935973)
235. Berkingali N, Warnecke A, Gomes P et al. Neurite outgrowth on cultured spiral ganglion neurons induced by erythropoietin. Hearing Res. 2008;243:121-126.
236. Yin ZS, Zhang H, Gao W. Erythropoietin promotes functional recovery and enhances nerve regeneration after peripheral nerve injury in rats. AJNR. 31:509-515.
237. Aydin A, Ozden BC, Karamursel S, Solakoglu S, Aktas S, Erer M. Effect of hyperbaric oxygen therapy on nerve regeneration in early diabetes. Microsurg. 2004;24:255-261. (Pubitemid 38720809)
238. Bakker DJ. Hyperbaric oxygen therapy and the diabetic foot. Diabetes/Metabol Res and Reviews. 2000;16 Suppl 1:S55-58.
239. Tuma Junior P, Dias MD, Arrunategui G et al. Effect of hyperbaric oxygen on the regeneration of experimental crush injuries of nerves. Rev Hosp Clin Fac Med Sao Paulo. 1999;54:81-84.
240. Haapaniemi T, Nylander G, Kanje M, Dahlin L. Hyperbaric oxygen treatment enhances regeneration of the rat sciatic nerve. Exp Neurol. 1998;149:433-438. (Pubitemid 28115081)
241. Santos PM, Zamboni WA, Williams SL, Covey JF, Kienstra MA. Hyperbaric oxygen treatment after rat peroneal nerve transection and entubulation. Otolaryngol Head Neck Surg. 1996;114:424-434. (Pubitemid 26097132)