Antimalarial β-carboline and indolactam alkaloids from Marinactinospora thermotolerans, a deep sea isolate

Journal of Natural Products

Volumn 74, Issue 10, 2011, Pages 2122-2127

  Huang, Hongbo ^a   Yao, Yueliang ^a   He, Zhengxiang ^b   Yang, Tingting ^c   Ma, Junying ^a   Tian, Xinpeng ^a   Li, Yayong ^b   Huang, Caiguo ^c   Chen, Xiaoping ^b   Li, Wenjun ^d   Zhang, Si ^a   Zhang, Changsheng ^a   Ju, Jianhua ^a  

^a SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY   (China)

^b GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

^d YUNNAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 ACETYL BETA CARBOLINE; 13 N DEMETHYL METHYLPENDOLMYCIN; ALKALOID; ANTIMALARIAL AGENT; BETA CARBOLINE; INDOLACTAM ALKALOID; MARINACARBOLINE A; MARINACARBOLINE B; MARINACARBOLINE C; MARINACARBOLINE D; METHYLPENDOLMYCIN; METHYLPENDOLMYCIN 14ALPHA GLUCOSIDE; PENDOLMYCIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG ISOLATION; DRUG STRUCTURE; FERMENTATION; IC 50; MARINACTINOSPORA THERMOTOLERANS; MASS SPECTROMETRY; NOCARDIACEAE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLASMODIUM FALCIPARUM; X RAY CRYSTALLOGRAPHY;

ACTINOMYCETALES; ALKALOIDS; ANTIMALARIALS; ANTINEOPLASTIC AGENTS; CARBOLINES; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MARINE BIOLOGY; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PLASMODIUM FALCIPARUM;

NOCARDIOPSACEAE; PLASMODIUM FALCIPARUM;

EID: 80055091302     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np200399t     Document Type: Article

References (30)

1. Berdy, J. J. Antibiot. 2005, 58, 1-26
2. Fenical, W.; Jensen, P. R. Nat. Chem. Biol. 2006, 2, 666-673
3. Lam, K. S. Curr. Opin. Microbiol. 2006, 9, 245-251
4. Williams, P. G.; Buchanan, G. O.; Feling, R. H.; Kauffman, C. A.; Jensen, P. R.; Fenical, W. J. Org. Chem. 2005, 70, 6196-6203
5. Riedlinger, J.; Reicke, A.; Zähner, H.; Krismer, B.; Bull, A. T.; Maldonado, L. A.; Ward, A. C.; Goodfellow, M.; Bister, B.; Bischoff, D.; Süssmuth, R. D.; Fiedler, H. P. J. Antibiot. 2004, 57, 271-279
6. Bister, B.; Bischoff, D.; Ströbele, M.; Riedlinger, J.; Reicke, A.; Wolter, F.; Bull, A. T.; Zähner, H.; Fiedler, H.-P.; Süssmuth, R. D. Angew. Chem., Int. Ed. 2004, 43, 2574-2576
7. Kwon, H. C.; Kauffman, C. A.; Jensen, P. R.; Fenical, W. J. Am. Chem. Soc. 2006, 128, 1622-1632
8. Tian, X. P.; Tang, S. K.; Dong, J. D.; Zhang, Y. Q.; Xu, L. H.; Zhang, S.; Li, W. J. Int. J. Syst. Evol. Microbiol. 2009, 59, 948-952
9. Tian, X. P.; Zhi, X. Y.; Qiu, Y. Q.; Zhang, Y. Q.; Tang, S. K.; Xu, L. H.; Zhang, S.; Li, W. J. Int. J. Syst. Evol. Microbiol. 2009, 59, 222-228
10. Tian, X. P.; Zhang, Y. Q.; Li, Q. X.; Zhi, X. Y.; Tang, S. K.; Zhang, S.; L, W. J. Int. J. Syst. Evol. Microbiol. 2009, 59, 745-749
11. Duan, C.; Yao, Y.; Wang, Z.; Tian, X.; Zhang, S.; Zhang, C.; Ju, J. Chin. J. Mar. Drugs 2010, 29, 12-20
12. Shin, H. J.; Lee, H.-S.; Lee, D.-S. J. Microbiol. Biotechnol. 2010, 20, 501-505
13. Sun, H. H.; White, C. B.; Dedinas, J.; Cooper, R.; Sedlock, D. M. J. Nat. Prod. 1991, 54, 1440-1443
14. Yamashita, T.; Imoto, M.; Isshiki, K.; Sawa, T.; Naganawa, H.; Kurasawa, S.; Zhu, B.-Q.; Umezawa, K. J. Nat. Prod. 1988, 51, 1184-1187
15. Sun, B.; Morikawa, T.; Matsuda, H.; Tewtrakul, S.; Wu, L. J.; Harima, S.; Yoshikawa, M. J. Nat. Prod. 2004, 67, 1464-1469
16. Wang, W.; Nam, S.-J.; Lee, B.-C.; Kang, H. J. Nat. Prod. 2008, 71, 163-166
17. Aimi, N.; Odaka, H.; Sakai, S.; Fujiki, H.; Suganuma, M.; Moore, R. E.; Patterson, G. M. L. J. Nat. Prod. 1990, 53, 1593-1596
18. Edwards, D. J.; Gerwick, W. H. J. Am. Chem. Soc. 2004, 126, 11432-11433
19. Endo, Y.; Hasegawa, M.; Itai, A.; Shudo, K. Tetrahedron 1987, 43, 3695-3704
20. Cao, R.; Peng, W.; Wang, Z.; Xu, A. Curr. Med. Chem. 2007, 14, 479-500
21. Ang, K. K.; Holmes, M. J.; Higa, T.; Hamann, M. T.; Kara, U. A. Antimicrob. Agents Chemother. 2000, 44, 1645-1649
22. Rottmann, M.; McNamara, C.; Yeung, B. K. S.; Le, M. C. S.; Zou, B.; Russell, B.; Seitz, P.; Plouffe, D. M.; Dharia, N. V.; Tan, J.; Cohen, S. B.; Spencer, K. R.; González-Páez, G. E.; Lakshminarayana, S. B.; Goh, A.; Suwanarusk, R.; Jegla, T.; Schmitt, E. K.; Beck, H. P.; Brun, R.; Nosten, F.; Renia, L.; Dartois, V.; Keller, T. H.; Fidock, D. A.; Winzeler, E. A.; Diagana, T. T. Science 2010, 329, 1175-1180
23. Cardellina, J. H., II; Marner, F.-J.; Moore, R. E. Science 1979, 204, 193-195
24. Sakai, S.; Aimi, N.; Yamaguchi, K.; Hitotsuyanagi, Y.; Watanabe, C.; Yokose, K.; Koyama, Y.; Shudo, K.; Itai, A. Chem. Pharm. Bull. 1984, 32, 354-357
25. Izumikawa, M.; Khan, S. T.; Komaki, H.; Takagi, M.; Shin-ya, K. J. Antibiot. 2010, 63, 33-36
26. Fujiki, H.; Mori, M.; Nakayasu, M.; Terada, M.; Sugimura, T.; Moore, R. E. Proc. Natl. Acad. Sci. U.S.A. 1981, 78, 3872-3876
27. Nakagawa, Y.; Irie, K.; Yanagita, R. C.; Ohigashi, H.; Tsuda, K. J. Am. Chem. Soc. 2005, 127, 5746-5747
28. Mosmann, T. J. Immunol. Methods 1983, 65, 55-63
29. He, Z.; Chen, L.; You, J.; Qin, L.; Chen, X. Int. J. Antimicrob. Agents 2010, 35, 191-193
30. Sheldrick, G. M. SHELXTL-97, Program for Crystal Structure Solution and Refinement; University of Göttingen, Göttingen, Germany, 1997.