Phase II clinical study of boron neutron capture therapy combined with X-ray radiotherapy/temozolomide in patients with newly diagnosed glioblastoma multiforme-Study design and current status report

Applied Radiation and Isotopes

Volumn 69, Issue 12, 2011, Pages 1796-1799

  Kawabata, Shinji ^a   Miyatake, Shin Ichi ^a   Hiramatsu, Ryo ^a   Hirota, Yuki ^a   Miyata, Shiro ^a   Takekita, Yoko ^a   Kuroiwa, Toshihiko ^a   Kirihata, Mitsunori ^b   Sakurai, Yoshinori ^c   Maruhashi, Akira ^c   Ono, Koji ^c  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b Osaka Prefecture University   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Boron neutron capture therapy; Fractionated X ray irradiation; Glioblastoma; Phase II clinical study; Temozolomide

Indexed keywords

BORON NEUTRON CAPTURE THERAPY; GLIOBLASTOMAS; PHASE II; TEMOZOLOMIDE; X RAY IRRADIATION;

BORON; BORON COMPOUNDS; IRRADIATION; NEUTRONS; SODIUM; X RAYS;

PATIENT TREATMENT;

4 BORONOPHENYLALANINE; BORON DERIVATIVE; SODIUM BOROCAPATE; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

ARTICLE; BLOOD TOXICITY; BONE MARROW TOXICITY; BRAIN EDEMA; BRAIN NECROSIS; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL EFFECTIVENESS; CLINICAL PROTOCOL; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG SAFETY; EXTERNAL BEAM RADIOTHERAPY; GLIOBLASTOMA; HUMAN; JAPAN; NEUTRON CAPTURE THERAPY; OVERALL SURVIVAL; PRIORITY JOURNAL; RADIATION DOSE; SEIZURE; SIDE EFFECT; SURVIVAL TIME; X IRRADIATION;

ANTINEOPLASTIC AGENTS; BORON NEUTRON CAPTURE THERAPY; BRAIN NEOPLASMS; COMBINED MODALITY THERAPY; DACARBAZINE; GLIOBLASTOMA; HUMANS;

EID: 80055090949     PISSN: 09698043     EISSN: 18729800     Source Type: Journal    
DOI: 10.1016/j.apradiso.2011.03.014     Document Type: Article

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