Survival benefit from boron neutron capture therapy for the newly diagnosed glioblastoma patients

Applied Radiation and Isotopes

Volumn 67, Issue 7-8 SUPPL., 2009, Pages

  Kawabata, Shinji ^a   Miyatake, Shin Ichi ^a   Nonoguchi, Naosuke ^a   Hiramatsu, Ry ^a   Iida, Kyoko ^a   Miyata, Shiro ^a   Yokoyama, Kunio ^a   Doi, Atsushi ^a   Kuroda, Yuzo ^a   Kuroiwa, Toshihiko ^a   Michiue, Hiroyuki ^b   Kumada, Hiroaki ^c   Kirihata, Mitsunori ^d   Imahori, Yoshio ^e   Maruhashi, Akira ^f   Sakurai, Yoshinori ^f   Suzuki, Minoru ^f   Masunaga, Shin Ichiro ^f   Ono, Koji ^f  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c JAPAN ATOMIC ENERGY AGENCY   (Japan)

^d Osaka Prefecture University   (Japan)

^e Cancer Intelligence Care Systems Inc   (Japan)

^f KYOTO UNIVERSITY   (Japan)

Author keywords

Boron neutron capture therapy; BPA; BSH; External beam X ray irradiation; Glioblastoma

Indexed keywords

BORON NEUTRON CAPTURE THERAPY; BPA; BSH; EXTERNAL BEAM X-RAY IRRADIATION; GLIOBLASTOMA;

AMINO ACIDS; BORON; BORON COMPOUNDS; CHEMOTHERAPY; NEUTRONS; PATIENT MONITORING; SODIUM; X RAYS;

NEUTRON IRRADIATION;

4 BORONOPHENYLALANINE; BOROCAPTATE; NIMUSTINE;

ARTICLE; CANCER SURGERY; CANCER SURVIVAL; CLINICAL ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; EXTERNAL BEAM RADIOTHERAPY; GLIOBLASTOMA; HUMAN; NEUTRON CAPTURE THERAPY; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; RADIATION SICKNESS;

BOROHYDRIDES; BORON COMPOUNDS; BORON NEUTRON CAPTURE THERAPY; BRAIN NEOPLASMS; CLINICAL PROTOCOLS; COMBINED MODALITY THERAPY; GLIOBLASTOMA; HUMANS; JAPAN; PHENYLALANINE; PROGNOSIS; RADIATION-SENSITIZING AGENTS; SULFHYDRYL COMPOUNDS; SURVIVAL RATE;

EID: 67649390794     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apradiso.2009.03.015     Document Type: Article

References (11)

1. Barth R.F., Coderre J.A., Vicente M.G., and Blue T.E. Boron neutron capture therapy of cancer: current status and future prospects. Clin. Cancer Res. 11 (2005) 3987-4002
2. Barth R.F., Grecula J.C., Yang W., Rotaru J.H., Nawrocky M., Gupta N., Albertson B.J., Ferketich A.K., Moeschberger M.L., Coderre J.A., and Rofstad E.K. Combination of boron neutron capture therapy and external beam radiotherapy for brain tumors. Int. J. Radiat. Oncol. Biol. Phys. 58 (2004) 267-277
3. Curran Jr. W.J., Scott C.B., Horton J., Nelson J.S., Weinstein A.S., Fischbach A.J., Chang C.H., Rotman M., Asbell S.O., Krisch R.E., and Nelson D.F. Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials. J. Natl. Cancer Inst. 85 (1993) 704-710
4. Doi A., Kawabata S., Iida K., Yokoyama K., Kajimoto Y., Kuroiwa T., Shirakawa T., Kirihata M., Kasaoka S., Maruyama K., Kumada H., Sakurai Y., Masunaga S., Ono K., and Miyatake S. Tumor-specific targeting of sodium borocaptate (BSH) to malignant glioma by transferrin-PEG liposomes: a modality for boron neutron capture therapy. J. Neuro-Oncol. 87 (2008) 287-294
5. Imahori Y., Ueda S., Ohmori Y., Sakae K., Kusuki T., Kobayashi T., Takagaki M., Ono K., Ido T., and Fujii R. Positron emission tomography-based boron neutron capture therapy using boronophenylalanine for high-grade gliomas: part I and II. Clin. Cancer Res. 4 (1998) 1825-1841
6. Kawabata S., Miyatake S., Kajimoto Y., Kuroda Y., Kuroiwa T., Imahori Y., Kirihata M., Sakurai Y., Kobayashi T., and Ono K. The early successful treatment of glioblastoma patients with modified boron neutron capture therapy. Report of two cases. J Neuro-Oncol. 65 (2003) 159-165
7. Miyatake S., Kawabata S., Kajimoto Y., Aoki A., Yokoyama K., Yamada M., Kuroiwa T., Tsuji M., Imahori Y., Kirihata M., Sakurai Y., Masunaga S., Nagata K., Maruhashi A., and Ono K. Modified boron neutron capture therapy for malignant gliomas performed using epithermal neutron and two boron compounds with different accumulation mechanisms: an efficacy study based on findings on neuroimages. J. Neurosurg. 103 (2005) 1000-1009
8. Ono K., Masunaga S., Suzuki M., Kinashi Y., Takagaki M., and Akaboshi M. The combined effect of boronophenylalanine and borocaptate in boron neutron capture therapy for SCCVII tumors in mice. Int. J. Radiat. Oncol. Biol. Phys. 43 (1999) 431-436
9. Ono, K., Sakurai, Y., Masunaga, S., Kinashi, Y., Takagaki, M., Kobayashi, T., 2000. Improvement of B-10 dose distribution in water phantom irradiated with epithermal neutron beam and its assessment by colony formation assay. In: Program and Abstracts of the Ninth International Symposium on Neutron Capture Therapy for Cancer. Kyoto University Research Reactor Institute, Osaka, Japan, pp. 197-198.
10. Sakurai Y., Ono K., Miyatake S., and Maruhashi A. Improvement effect on the depth-dose distribution by CSF drainage and air infusion of a tumour-removed cavity in boron neutron capture therapy for malignant brain tumours. Phys. Med. Biol. 51 (2006) 1173-1183
11. Yokoyama K., Miyatake S., Kajimoto Y., Kawabata S., Doi A., Yoshida T., Asano T., Kirihata M., Ono K., and Kuroiwa T. Pharmacokinetic study of BSH and BPA in simultaneous use for BNCT. J. Neuro-Oncol. 78 (2006) 227-232