Improvement effect on the depth-dose distribution by CSF drainage and air infusion of a tumour-removed cavity in boron neutron capture therapy for malignant brain tumours

Physics in Medicine and Biology

Volumn 51, Issue 5, 2006, Pages 1173-1183

  Sakurai, Yoshinori ^a   Ono, Koji ^a   Miyatake, Shin Ichi ^b   Maruhashi, Akira ^a  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; BRAIN; CAVITATION; COMPUTER SIMULATION; CORRELATION METHODS; FLUES; NEUTRONS; TUMORS;

BORON NEUTRON CAPTURE THERAPY (BNCT); CEREBRO SPINAL FLUID (CSF); DEPTH DOSE DISTRIBUTION; MALIGNANT BRAIN TUMORS;

DISEASE CONTROL;

BORON;

ARTICLE; BRAIN CANCER; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID DRAINAGE; COMPUTER SIMULATION; CRANIOTOMY; DISEASE SIMULATION; INFUSION; NEUTRON CAPTURE THERAPY; NEUTRON THERAPY; PHANTOM; PRIORITY JOURNAL; RADIATION DEPTH DOSE; RADIATION DOSE DISTRIBUTION; SURGICAL TECHNIQUE;

AIR; BORON NEUTRON CAPTURE THERAPY; BRAIN NEOPLASMS; CEREBROSPINAL FLUID; CRANIOTOMY; DRAINAGE; HUMANS; PHANTOMS, IMAGING;

EID: 33144472539     PISSN: 00319155     EISSN: None     Source Type: Journal    
DOI: 10.1088/0031-9155/51/5/009     Document Type: Article

References (15)

1. Briesmeister J F 2000 MCNP-a general Monte Carlo n-particle transport code version 4C, LA-13709-M
2. Brugger R M, Constantine G, Harling O K and Wheeler F J 1990 Rapporteurs' report Neutron Beam Design, Development, and Performance for Neutron Capture Therapy ed O K Harling et al (New York: Plenum) pp 3-12
3. Hatanaka H and Urano Y 1986 Clinical experience of boron-neutron capture therapy for gliomas-a comparison with conventional chemo-immuno-radiotherapy Boron-Neutron Capture Therapy for Tumor ed H Hatanaka (Niigata: Nishimura) pp 349-416
4. Kawabata S, Miyatake S, Kajimoto Y, Kuroda Y, Kuroiwa T, Imahori Y, Kirihata M, Sakurai Y, Kobayashi T and Ono K 2003 The early successful treatment of glioblastoma patients with modified boron neutron capture therapy J. Neurol. Oncol. 65 159-66
5. Locher G L 1936 Biological effects and therapeutic possibilities of neutron Am. J. Roentgenol. 36 1-13
6. Miyatake S, Kajimoto Y, Kawabata S, Kuroda Y, Kuroiwa T, Imahori Y, Kirihata M, Sakurai Y, Kobayashi T and Ono K 2002 Experience of modified boron neutron capture therapy to a glioblastoma patient Research and Development in Neutron Capture Therapy ed W Sauerwein et al (Bologna: Monduzzi Editore) pp 1129-33
7. Ommaya A K 1984 Implantable devices for chronic access and drug delivery to the central nervous system Cancer Drug Deliv. 1 169-79
8. Ono K, Masunaga S, Suzuki M, Kinashi Y, Takagaki M and Akaboshi M 1999 The combined effect of boronophenylalanine and borocaptate in boron neutron capture therapy for SCCVII tumors in mice Int. J. Radiat. Oncol. Biol. Phys. 43 431-6
9. Ono K, Sakurai Y, Masunaga S, Kinashi Y, Takagaki M and Kobayashi T 2000 Improvement of B-10 dose distribution in water phantom irradiated with epithermal neutron beam and its assessment by colony formation assay Program and Abstracts of the 9th Int. Symp. on Neutron Capture Therapy for Cancer (Kyoto University Research Reactor Institute) pp 197-8
10. Sakurai Y 2004 Studies on depth-dose-distribution controls by deuteration and void formation in boron neutron capture therapy Phys. Med. Biol. 49 3367-78
11. Sakurai Y and Kobayashi T 2000 Characteristics of the KUR Heavy Water Neutron Irradiation Facility as a neutron irradiation field with variable energy spectra Nucl. Instrum. Methods A 453 569-96
12. Sakurai Y and Kobayashi T 2002 Controllability of depth dose distribution for neutron capture therapy at the Heavy Water Neutron Irradiation Facility of Kyoto University Research Reactor Med. Phys. 29 2328-37
13. Sakurai Y, Kobayashi T, Ono K, Sato T and Kanda K 1992 A study on the improvement of thermal neutron dose distribution in tissue for neutron capture therapy Annu. Rep. Res. Reactor Inst. Kyoto Univ. 25 63-77
14. Wessol D, Cohen M, Harkin G, Rossmeier M, Wemple C and Wheeler F 1999 SERA Workshop Lab Manual INEEL/EXT-99-00766
15. Yamamoto T, Matsumura A, Yamamoto K, Kumada H, Shibata Y and Nose T 2002 In-phantom two dimensional thermal neutron distribution for intraoperative boron neutron capture therapy of brain tumors Phys. Med. Biol. 47 2387-96