Human beta-defensin-3 (hBD-3) upregulated by LPS via epidermal growth factor receptor (EGFR) signaling pathways to enhance lymphatic invasion of oral squamous cell carcinoma

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology

Volumn 112, Issue 5, 2011, Pages 616-625

  Shuyi, Yu ^a,b   Feng, Wang ^b   Jing, Tang ^b   Hongzhang, Huang ^c   Haiyan, Wang ^b   Pingping, Ma ^b   Liwu, Zheng ^b,d   Zwahlen, Roger A ^b,d   Hongyu, Yang ^b,d  

^a Biomedical Research Institute   (China)

^b PEKING UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN; BETA DEFENSIN 3, HUMAN; BETA-DEFENSIN 3, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR; LIPOPOLYSACCHARIDE;

ARTICLE; CANCER INVASION; CHEMOTAXIS; DRUG EFFECT; GENE EXPRESSION REGULATION; HUMAN; IMMUNOLOGY; LYMPH NODE METASTASIS; LYMPHANGIOGENESIS; METABOLISM; MOUTH TUMOR; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; TUMOR CELL CULTURE;

BETA-DEFENSINS; CARCINOMA, SQUAMOUS CELL; CHEMOTAXIS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIPOPOLYSACCHARIDES; LYMPHANGIOGENESIS; LYMPHATIC METASTASIS; MOUTH NEOPLASMS; NEOPLASM INVASIVENESS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 80055085570     PISSN: 10792104     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tripleo.2011.02.053     Document Type: Article

References (23)

1. S. Pushalkar, S.P. Mane, X. Ji, Y. Li, C. Evans, and O.R. Crasta Microbial diversity in saliva of oral squamous cell carcinoma FEMS Immunol Med Microbiol 61 2011 269 277
2. L. Guillot, S. Medjane, K. Le-Barillec, V. Balloy, C. Danel, and M. Chignard Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: evidence for an intracellular compartmentalization of TLR4 J Biol Chem 279 2004 2712 2718 (Pubitemid 38114260)
3. K. Harada, S. Ohira, K. Isse, S. Ozaki, Y. Zen, and Y. Sato Lipopolysaccharide activates nuclear factor-κβ through Toll-like receptors and related molecules in cultured biliary epithelial cells Lab Invest 83 2003 1657 1667 (Pubitemid 37421106)
4. M.X. Shao, I.F. Ueki, and J.A. Nadel Tumor necrosis factor α-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells Proc Natl Acad Sci U S A 100 2003 11618 11623 (Pubitemid 37205985)
5. L. Finzi, X.G. Matt, F. Shao, C. Housset, and J.A. Nadel Lipopolysaccharide initiates a positive feedback of epidermal growth factor receptor signaling by prostaglandin E2 in human biliary carcinoma cells J Immunol 82 2009 2269 2276
6. S.J. Hooper, S.J. Crean, M.J. Fardy, M.A. Lewis, D.A. Spratt, and W.G. Wade A molecular analysis of the bacteria present within oral squamous cell carcinoma J Med Microbiol 56 2007 1651 1659 (Pubitemid 350276516)
7. K.G. Kohlgraf, L.C. Pingel, D.E. Dietrich, and K.A. Brogden Defensins as anti-inflammatory compounds and mucosal adjuvants Future Microbiol 5 2010 99 113
8. O.E. Sørensen, D.R. Thapa, A. Rosenthal, L. Liu, A.A. Roberts, and T. Ganz Differential regulation of beta-defensin expression in human skin by microbial stimuli J Immunol 174 2005 4870 4879
9. L. Yin, T. Chino, O.V. Horst, B.M. Hacker, E.A. Clark, and B.A. Dale Differential and coordinated expression of defensins and cytokines by gingival epithelial cells and dendritic cells in response to oral bacteria BMC Immunol 11 2010 37
10. P. Chadebech, D. Goidin, C. Jacquet, J. Viac, D. Schmitt, and M.J. Staquet Use of human reconstructed epidermis to analyze the regulation of beta-defensin hBD-1, hBD-2, and hBD-3 expression in response to LPS Cell Biol Toxicol 19 2003 313 324 (Pubitemid 38002151)
11. H. Takada Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines Mol Immunol 45 2008 3505 3507
12. N. Steubesand, K. Kiehne, G. Brunke, R. Pahl, K. Reiss, and K.H. Herzig The expression of the β-defensins hBD-2 and hBD-3 is differentially regulated by NF-κB and MAPK/AP-1 pathways in an in vitro model of Candida esophagitis BMC Immunol 10 2009 36 42
13. S. Joly, L.M. Compton, C. Pujol, Z.B. Kurago, and J.M. Guthmiller Loss of human beta-defensin 1, 2, and 3 expression in oral squamous cell carcinoma Oral Microbiol Immunol 24 2009 353 360
14. T. Yoshimoto, T. Yamaai, N. Mizukawa, K. Sawaki, M. Nakano, and E. Yamachika Different expression patterns of beta-defensins in human squamous cell carcinomas Anticancer Res 23 2003 4629 4633 (Pubitemid 38173877)
15. J.J. Sheu, C.H. Hua, L. Wan, Y.J. Lin, M.T. Lai, and H.C. Tseng Functional genomic analysis identified epidermal growth factor receptor activation as the most common genetic event in oral squamous cell carcinoma Cancer Res 69 2009 2568 2576
16. M.R. Kesting, D.J. Loeffelbein, R.J. Hasler, K.D. Wolff, A. Rittig, and M. Schulte Expression profile of human beta-defensin 3 in oral squamous cell carcinoma Cancer Invest 27 2009 575 581
17. H.I. Kawsar, A. Weinberg, S.A. Hirsch, A. Venizelos, S. Howell, and G. Jin Overexpression of human b-defensin-3 in oral dysplasia: potential role in macrophage trafficking Oral Oncol 45 2009 12 17
18. G. Jin, H.I. Kawsar, S.A. Hirsch, C. Zeng, X. Jia, and Z. Feng An antimicrobial peptide regulates tumor-associated macrophage trafficking via the chemokine receptor CCR2, a model for tumorigenesis PLoS ONE 5 2010 1 14
19. S.A. Sarkis, B.H. Abdullah, B.A. Majeed, and N.G. Talabani Immunohistochemical expression of epidermal growth factor receptor (EGFR) in oral squamous cell carcinoma in relation to proliferation, apoptosis, angiogenesis and lymphangiogenesis Head Neck Oncol 2 2010 13 21
20. A. De Luca, A. Carotenuto, A. Rachiglio, M. Gallo, M.R. Maiello, and D. Aldinucci The role of the EGFR signaling in tumor microenvironment J Cell Physiol 214 2008 559 567 (Pubitemid 351224199)
21. N. Normanno, C. Bianco, D.A. Luca, and D.S. Salomon The role of EGF-related peptides in tumor growth Front Biosci 6 2001 D685 D707
22. S. Bauer, T. Mller, and S. Hamm Pattern recognition by Toll-like receptors Adv Exp Med Biol 653 2009 15 34
23. M.J. Szczepanski, M. Czystowska, M. Szajnik, M. Harasymczuk, M. Boyiadzis, and A. Kruk-Zagajewska Triggering of Toll-like receptor 4 expressed on human head and neck squamous cell carcinoma promotes tumor development and protects the tumor from immune attack Cancer Res 69 2009 3105 3113