Novel mouse xenograft models reveal a critical role of CD4 + T cells in the proliferation of ebv-infected T and NK cells

PLoS Pathogens

Volumn 7, Issue 10, 2011, Pages

  Imadome, Ken Ichi ^a   Yajima, Misako ^a   Arai, Ayako ^b   Nakazawa, Atsuko ^c   Kawano, Fuyuko ^a   Ichikawa, Sayumi ^a,b   Shimizu, Norio ^b   Yamamoto, Naoki ^d   Morio, Tomohiro ^b   Ohga, Shouichi ^e   Nakamura, Hiroyuki ^a   Ito, Mamoru ^f   Miura, Osamu ^b   Komano, Jun ^d   Fujiwara, Shigeyoshi ^a  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^d NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^e KYUSHU UNIVERSITY   (Japan)

^f CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; EPSTEIN BARR VIRUS ANTIGEN 1; GAMMA INTERFERON; INTERLEUKIN 8; LATENT MEMBRANE PROTEIN 1; LATENT MEMBRANE PROTEIN 2; OKT 4; RANTES;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHILD; CONTROLLED STUDY; CYTOKINE STORM; ENGRAFTMENT; EPSTEIN BARR VIRUS; EPSTEIN BARR VIRUS INFECTION; FEMALE; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; IN VIVO STUDY; LYMPHOCYTE CLONE; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SCHOOL CHILD; XENOTRANSPLANTATION; ANIMAL; CANCER TRANSPLANTATION; CELL CULTURE; CELL PROLIFERATION; CHRONIC DISEASE; DISEASE MODEL; HOST PATHOGEN INTERACTION; IMMUNOLOGY; INFANT; MIDDLE AGED; MOUSE MUTANT; NONOBESE DIABETIC MOUSE; PHYSIOLOGY; VIROLOGY; XENOGRAFT;

ANIMALIA; HERPESVIRIDAE; HUMAN HERPESVIRUS 4; MUS;

ADOLESCENT; ADULT; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; CHILD; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; HERPESVIRUS 4, HUMAN; HOST-PATHOGEN INTERACTIONS; HUMANS; INFANT; KILLER CELLS, NATURAL; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MALE; MICE; MICE, INBRED NOD; MICE, SCID; MIDDLE AGED; NEOPLASM TRANSPLANTATION; TRANSPLANTATION, HETEROLOGOUS;

EID: 80055085376     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002326     Document Type: Article

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