Fatal cytotoxic T-cell proliferation in chronic active Epstein-Barr virus infection in childhood

American Journal of Clinical Pathology

Volumn 117, Issue 2, 2002, Pages 283-290

  Nakagawa, Atsuko ^a   Ito, Masafumi ^a   Saga, Shinsuke ^a  

^a AICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Childhood; Chronic active Epstein Barr virus infection; Cytotoxic T cell; Immunohistochemistry; Lymphoproliferative disorder

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; EPSTEIN BARR VIRUS ANTIGEN; EPSTEIN BARR VIRUS NUCLEAR ANTIGEN 2; LATENT MEMBRANE PROTEIN 1; RNA; UNCLASSIFIED DRUG;

ARTICLE; AUTOPSY; BONE MARROW; CELL PROLIFERATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DISEASE ASSOCIATION; DISEASE SEVERITY; EPSTEIN BARR VIRUS; FEMALE; GENE REARRANGEMENT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KIDNEY; LIVER; LUNG; LYMPH NODE; LYMPHOCYTIC INFILTRATION; MALE; MALIGNANT NEOPLASTIC DISEASE; MORTALITY; ONSET AGE; PRIORITY JOURNAL; SKIN DEFECT; SOUTHERN BLOTTING; SPLEEN; T LYMPHOCYTE; VASCULITIS; VIRUS INFECTION;

ANTIBODIES, VIRAL; ANTIGENS, CD3; ANTIGENS, CD8; CELL DIVISION; CELL NUCLEUS; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; DISEASE PROGRESSION; EPSTEIN-BARR VIRUS INFECTIONS; FATAL OUTCOME; FEMALE; GENE REARRANGEMENT, T-LYMPHOCYTE; HUMANS; IMMUNOPHENOTYPING; MALE; ORGAN SPECIFICITY; RNA, VIRAL; SEROLOGIC TESTS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0036325572     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/9PPA-BKB7-YKAQ-ALX5     Document Type: Article

References (36)

1. Chronic, symptomatic Epstein-Barr virus infection
2. Persistent Epstein-Barr virus infection in a child with hypergammaglobulinemia and immunoblastic proliferation associated with a selective defect in immune interferon secretion
3. Chronic active Epstein-Barr virus infection in children in Japan
4. Severe chronic active Epstein-Barr virus infection syndrome
5. Prolonged atypical illness associated with serological evidence of persistent Epstein-Barr virus infection
6. Evidence for active Epstein-Barr virus infection in patients with persistent unexpected illnesses: Elevated anti-early antigen antibodies
7. Pathogenesis of chronic active Epstein-Barr virus infection
8. Epstein-Barr virus genome-positive T lymphocytes in a boy with chronic active EBV infection, associated with Kawasaki like disease
9. Fulminant EBV(+) T-cell lymphoproliferative disorder following acute/chronic EBV infection: A distinct clinicopathologic syndrome
10. Clonal T-cell lymphoproliferation containing Epstein-Barr (EB) virus DNA in a patient with chronic active EB virus infection
11. Clinico- pathological study of severe chronic active Epstein-Barr virus infection that developed in association with lymphoproliferative disorder and/or hemophagocytic syndrome
12. Persistent active Epstein-Barr virus infection and atypical lymphoproliferation: Report of two cases
13. T-cell lymphomas containing Epstein-Barr viral DVA in patients with chronic Epstein-Barr virus infections
14. EBV infection induced transformation of benign T lymphoproliferative state in patient with chronic active EBV infection into malignant lymphoma: Implication of EBV infection as additive oncogenic factor in tumorigenesis
15. A syndrome of peripheral blood T-cell infection with Epstein-Barr virus (EBV) followed by EBV-positive T-cell lymphoma
16. Severe chronic EBV infection associated with specific EBV immunodeficiency and an EBNA+ T-cell lymphoma containing linear EBV DNA
17. Chronic active Epstein- Barr virus infection with giant coronary aneurysms
18. Detection and localization of Epstein-Barr viral genomes in angioimmunoblastic lymphadenopathy and angioimmunoblastic lymphadenopathy-like lymphoma
19. NIH conference: Epstein-Barr virus infections: Biology, pathogenesis, and management
20. Epstein-Barr virus-associated peripheral T-cell lymphoma of activated CD8 phenotype
21. A novel form of Epstein-Barr virus latency in normal B cells in vivo
22. Epstein-Barr virus-infected B cells of males with the X-linked lymphoproliferative syndrome stimulate and are susceptible to T-cell-mediated lysis
23. Characterization of the T cell-mediated cellular cytotoxicity during acute infectious mononucleosis
24. Epstein-Barr virus replication in oropharyngeal epithelial cells
25. Evidence for lytic infection by Epstein-Barr virus in mucosal lymphocytes instead of nasopharyngeal epithelial cells in normal individuals
26. Analysis of the pathogenesis in patients with chronic active EBV infection
27. Fatal infectious mononucleosis: A critical review
28. Fatal infectious mononucleosis and virus associated hemophagocytic syndrome
29. X-linked lymphoproliferative syndrome
30. Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene
31. X-linked lymphoproliferative disease: Pathology and diagnosis
32. X-linked lymphoproliferative syndrome: An immunodeficiency disorder with acquired agammaglobulinemia, fatal infectious mononucleosis, or malignant lymphoma
33. Expression of Epstein-Barr virus-encoded proteins and B-cell markers in fatal infectious mononucleosis
34. Immunohistological studies of lymphoproliferative lesions in a fatal case of Epstein-Barr virus infection
35. Hepatitis in fatal infectious mononucleosis
36. Lymphocytic vasculitis in X-linked lymphoproliferative disease